Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1PMD
DownloadVisualize
BU of 1pmd by Molmil
PENICILLIN-BINDING PROTEIN 2X (PBP-2X)
Descriptor: PEPTIDOGLYCAN SYNTHESIS MULTIFUNCTIONAL ENZYME
Authors:Pares, S, Mouz, N, Dideberg, O.
Deposit date:1996-02-05
Release date:1997-02-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme.
Nat.Struct.Biol., 3, 1996
1QMF
DownloadVisualize
BU of 1qmf by Molmil
PENICILLIN-BINDING PROTEIN 2X (PBP-2X) ACYL-ENZYME COMPLEX
Descriptor: 2-[CARBOXY-(2-FURAN-2-YL-2-METHOXYIMINO-ACETYLAMINO)-METHYL]-5-METHYL-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, CEFUROXIME (OCT-3-ENE FORM), PENICILLIN-BINDING PROTEIN 2X
Authors:Gordon, E.J, Mouz, N, Duee, E, Dideberg, O.
Deposit date:1999-09-28
Release date:2000-05-25
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Crystal Structure of the Penicillin Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance
J.Mol.Biol., 299, 2000
1QME
DownloadVisualize
BU of 1qme by Molmil
PENICILLIN-BINDING PROTEIN 2X (PBP-2X)
Descriptor: PENICILLIN-BINDING PROTEIN 2X, SULFATE ION
Authors:Gordon, E.J, Mouz, N, Duee, E, Dideberg, O.
Deposit date:1999-09-28
Release date:2000-05-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of the Penicillin-Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance.
J.Mol.Biol., 299, 2000
1K25
DownloadVisualize
BU of 1k25 by Molmil
PBP2x from a Highly Penicillin-resistant Streptococcus pneumoniae Clinical Isolate
Descriptor: low-affinity PENICILLIN-BINDING PROTEIN 2X
Authors:Dessen, A, Mouz, N, Hopkins, J, Dideberg, O.
Deposit date:2001-09-26
Release date:2001-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutations.
J.Biol.Chem., 276, 2001
1MWT
DownloadVisualize
BU of 1mwt by Molmil
Structure of penicillin G acyl-Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 2.45 A resolution.
Descriptor: CADMIUM ION, CHLORIDE ION, OPEN FORM - PENICILLIN G, ...
Authors:Lim, D.C, Strynadka, N.C.J.
Deposit date:2002-10-01
Release date:2002-11-06
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus.
Nat.Struct.Biol., 9, 2002
1MWR
DownloadVisualize
BU of 1mwr by Molmil
Structure of SeMet Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r (trigonal form) at 2.45 A resolution.
Descriptor: CADMIUM ION, CHLORIDE ION, penicillin-binding protein 2a
Authors:Lim, D.C, Strynadka, N.C.J.
Deposit date:2002-10-01
Release date:2002-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus.
Nat.Struct.Biol., 9, 2002
1MWS
DownloadVisualize
BU of 1mws by Molmil
Structure of nitrocefin acyl-Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 2.00 A resolution.
Descriptor: CADMIUM ION, CHLORIDE ION, penicillin-binding protein 2a
Authors:Lim, D.C, Strynadka, N.C.J.
Deposit date:2002-10-01
Release date:2002-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus.
Nat.Struct.Biol., 9, 2002
1MWU
DownloadVisualize
BU of 1mwu by Molmil
Structure of methicillin acyl-Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 2.60 A resolution.
Descriptor: (2R,4S)-2-[(1R)-1-{[(2,6-dimethoxyphenyl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CADMIUM ION, CHLORIDE ION, ...
Authors:Lim, D.C, Strynadka, N.C.J.
Deposit date:2002-10-01
Release date:2002-11-06
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus.
Nat.Struct.Biol., 9, 2002
1PYY
DownloadVisualize
BU of 1pyy by Molmil
Double mutant PBP2x T338A/M339F from Streptococcus pneumoniae strain R6 at 2.4 A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 6-O-octanoyl-beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, Penicillin-binding protein 2X, ...
Authors:Chesnel, L, Pernot, L, Lemaire, D, Champelovier, D, Croize, J, Dideberg, O, Vernet, T, Zapun, A.
Deposit date:2003-07-09
Release date:2003-09-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:The Structural Modifications Induced by the M339F Substitution in PBP2x from Streptococcus pneumoniae Further Decreases the Susceptibility to beta-Lactams of Resistant Strains
J.Biol.Chem., 278, 2003
1RP5
DownloadVisualize
BU of 1rp5 by Molmil
PBP2x from Streptococcus pneumoniae strain 5259 with reduced susceptibility to beta-lactam antibiotics
Descriptor: SULFATE ION, penicillin-binding protein 2x
Authors:Pernot, L, Chesnel, L, Legouellec, A, Croize, J, Vernet, T, Dideberg, O, Dessen, A.
Deposit date:2003-12-03
Release date:2004-02-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:A PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics.
J.Biol.Chem., 279, 2004
1VQQ
DownloadVisualize
BU of 1vqq by Molmil
Structure of Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 1.80 A resolution.
Descriptor: CADMIUM ION, CHLORIDE ION, penicillin-binding protein mecA, ...
Authors:Lim, D, Strynadka, N.C.J.
Deposit date:2004-12-17
Release date:2004-12-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus.
Nat.Struct.Biol., 9, 2002
2Z2M
DownloadVisualize
BU of 2z2m by Molmil
Cefditoren-Acylated Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae
Descriptor: (2R)-2-[(1R)-1-{[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-(METHOXYIMINO)ACETYL]AMINO}-2-OXOETHYL]-5-[(Z)-2-(4-METHYL-1,3-THIAZOL-5-YL)VINYL]-3,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC ACID, Penicillin-binding protein 2X, SULFATE ION
Authors:Yamada, M, Watanabe, T, Takeuchi, Y.
Deposit date:2007-05-23
Release date:2007-09-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Cefditoren Complexed with Streptococcus pneumoniae Penicillin-Binding Protein 2X: Structural Basis for its High Antimicrobial Activity
Antimicrob.Agents Chemother., 51, 2007
2Z2L
DownloadVisualize
BU of 2z2l by Molmil
Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae
Descriptor: Penicillin-binding protein 2X, SULFATE ION
Authors:Yamada, M, Watanabe, T, Takeuchi, Y.
Deposit date:2007-05-23
Release date:2007-09-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structure of Cefditoren Complexed with Streptococcus pneumoniae Penicillin-Binding Protein 2X: Structural Basis for its High Antimicrobial Activity
Antimicrob.Agents Chemother., 51, 2007
2ZC4
DownloadVisualize
BU of 2zc4 by Molmil
Penicillin-binding protein 2X (PBP 2X) acyl-enzyme complex (tebipenem) from Streptococcus pneumoniae
Descriptor: (4R,5S)-3-(1-(4,5-dihydrothiazol-2-yl)azetidin-3-ylthio)-5-((2S,3R)-3-hydroxy-1-oxobutan-2-yl)-4-methyl-4,5- dihydro-1H-pyrrole-2-carboxylic acid, Penicillin-binding protein 2X, SULFATE ION
Authors:Yamada, M, Watanabe, T, Takeuchi, Y.
Deposit date:2007-11-02
Release date:2008-04-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniae
Antimicrob.Agents Chemother., 52, 2008
2ZC3
DownloadVisualize
BU of 2zc3 by Molmil
Penicillin-binding protein 2X (PBP 2X) acyl-enzyme complex (biapenem) from Streptococcus pneumoniae
Descriptor: (4R,5S)-3-(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-ylsulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-meth yl-4,5-dihydro-1H-pyrrole-2-carboxylate, Penicillin-binding protein 2X, SULFATE ION
Authors:Yamada, M, Watanabe, T, Takeuchi, Y.
Deposit date:2007-11-02
Release date:2008-04-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniae
Antimicrob.Agents Chemother., 52, 2008
3EQU
DownloadVisualize
BU of 3equ by Molmil
Crystal structure of penicillin-binding protein 2 from Neisseria gonorrhoeae
Descriptor: GLYCEROL, Penicillin-binding protein 2, SULFATE ION
Authors:Powell, A.J, Deacon, A.M, Nicholas, R.A, Davies, C.
Deposit date:2008-10-01
Release date:2008-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance.
J.Biol.Chem., 284, 2009
3EQV
DownloadVisualize
BU of 3eqv by Molmil
Crystal structure of penicillin-binding protein 2 from Neisseria gonorrhoeae containing four mutations associated with penicillin resistance
Descriptor: GLYCEROL, Penicillin-binding protein 2, SULFATE ION
Authors:Powell, A.J, Deacon, A.M, Nicholas, R.A, Davies, C.
Deposit date:2008-10-01
Release date:2008-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance.
J.Biol.Chem., 284, 2009
2WAD
DownloadVisualize
BU of 2wad by Molmil
PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN 5204)
Descriptor: PENICILLIN-BINDING PROTEIN 2B, ZINC ION
Authors:Contreras-Martel, C, Dahout-Gonzalez, C, Dos-Santos-Martins, A, Kotnik, M, Dessen, A.
Deposit date:2009-02-05
Release date:2009-02-24
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci
J.Mol.Biol., 387, 2009
2WAF
DownloadVisualize
BU of 2waf by Molmil
PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN R6)
Descriptor: CHLORIDE ION, PENICILLIN-BINDING PROTEIN 2B
Authors:Contreras-Martel, C, Dahout-Gonzalez, C, Dos-Santos-Martins, A, Kotnik, M, Dessen, A.
Deposit date:2009-02-05
Release date:2009-02-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci
J.Mol.Biol., 387, 2009
2WAE
DownloadVisualize
BU of 2wae by Molmil
PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN 5204)
Descriptor: PENICILLIN-BINDING PROTEIN 2B, ZINC ION
Authors:Contreras-Martel, C, Dahout-Gonzalez, C, Dos-Santos-Martins, A, Kotnik, M, Dessen, A.
Deposit date:2009-02-05
Release date:2009-02-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci
J.Mol.Biol., 387, 2009
3OC2
DownloadVisualize
BU of 3oc2 by Molmil
Crystal structure of penicillin-binding protein 3 from Pseudomonas aeruginosa
Descriptor: CHLORIDE ION, Penicillin-binding protein 3
Authors:Sainsbury, S, Bird, L, Stuart, D.I, Owens, R.J, Ren, J, Oxford Protein Production Facility (OPPF)
Deposit date:2010-08-09
Release date:2010-11-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.968 Å)
Cite:Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms
J.Mol.Biol., 405, 2011
3OCN
DownloadVisualize
BU of 3ocn by Molmil
Crystal structure of penicillin-binding protein 3 from Pseudomonas aeruginosa in complex with ceftazidime
Descriptor: 1-({(2R)-2-[(1R)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-oxoethyl]-4-carboxy-3,6-dihydro-2H-1,3-thiazin-5-yl}methyl)pyridinium, penicillin-binding protein 3
Authors:Sainsbury, S, Bird, L, Stuart, D.I, Owens, R.J, Ren, J, Oxford Protein Production Facility (OPPF)
Deposit date:2010-08-10
Release date:2010-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms
J.Mol.Biol., 405, 2011
3OCL
DownloadVisualize
BU of 3ocl by Molmil
Crystal structure of penicillin-binding protein 3 from Pseudomonas aeruginosa in complex with carbenicillin
Descriptor: (2R,4S)-2-[(1R)-1-{[(2S)-2-carboxy-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, GLYCEROL, ...
Authors:Sainsbury, S, Bird, L, Stuart, D.I, Owens, R.J, Ren, J, Oxford Protein Production Facility (OPPF)
Deposit date:2010-08-10
Release date:2010-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms
J.Mol.Biol., 405, 2011
3PBO
DownloadVisualize
BU of 3pbo by Molmil
Crystal structure of PBP3 complexed with ceftazidime
Descriptor: ACYLATED CEFTAZIDIME, Penicillin-binding protein 3
Authors:Han, S.
Deposit date:2010-10-20
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 107, 2010
3PBT
DownloadVisualize
BU of 3pbt by Molmil
Crystal structure of PBP3 complexed with MC-1
Descriptor: (4S,7Z)-7-(2-amino-1,3-thiazol-4-yl)-1-[({4-[(2R)-2,3-dihydroxypropyl]-3-(4,5-dihydroxypyridin-2-yl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl}sulfonyl)amino]-4-formyl-10,10-dimethyl-1,6-dioxo-9-oxa-2,5,8-triazaundec-7-en-11-oate, Penicillin-binding protein 3
Authors:Han, S, Evdokimov, A.
Deposit date:2010-10-20
Release date:2010-12-22
Last modified:2012-02-08
Method:X-RAY DIFFRACTION (1.641 Å)
Cite:Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 107, 2010

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon