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4BJQ
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4bjq
CRYSTAL STRUCTURE OF E. COLI PENICILLIN BINDING PROTEIN 3, DOMAIN V88- S165
Descriptor:PENICILLIN BINDING PROTEIN TRANSPEPTIDASE DOMAIN PROTEIN (E.C.2.4.1.129)
Authors:Sauvage, E., Joris, M., Herman, R., Kerff, F., Rocaboy, M., Charlier, P.
Deposit date:2013-04-19
Release date:2014-05-07
Modification date:2014-06-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Penicillin-Binding Protein 3 (Pbp3) from Escherichia Coli.
Plos One, 9, 2014
1K25
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1k25
PBP2X FROM A HIGHLY PENICILLIN-RESISTANT STREPTOCOCCUS PNEUMONIAE CLINICAL ISOLATE
Descriptor:low-affinity Penicillin-binding protein 2X
Authors:Dessen, A., Mouz, N., Hopkins, J., Dideberg, O.
Deposit date:2001-09-26
Release date:2001-10-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutations.
J.Biol.Chem., 276, 2001
1PMD
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1pmd
PENICILLIN-BINDING PROTEIN 2X (PBP-2X)
Descriptor:PEPTIDOGLYCAN SYNTHESIS MULTIFUNCTIONAL ENZYME
Authors:Pares, S., Mouz, N., Dideberg, O.
Deposit date:1996-02-05
Release date:1997-02-05
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme.
Nat.Struct.Biol., 3, 1996
1PYY
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1pyy
DOUBLE MUTANT PBP2X T338A/M339F FROM STREPTOCOCCUS PNEUMONIAE STRAIN R6 AT 2.4 A RESOLUTION
Descriptor:Penicillin-binding protein 2X
Authors:Chesnel, L., Pernot, L., Lemaire, D., Champelovier, D., Croize, J., Dideberg, O., Vernet, T., Zapun, A.
Deposit date:2003-07-09
Release date:2003-09-30
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:The Structural Modifications Induced by the M339F Substitution in PBP2x from Streptococcus pneumoniae Further Decreases the Susceptibility to beta-Lactams of Resistant Strains
J.Biol.Chem., 278, 2003
1QME
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1qme
PENICILLIN-BINDING PROTEIN 2X (PBP-2X)
Descriptor:PENICILLIN-BINDING PROTEIN 2X
Authors:Gordon, E.J., Mouz, N., Duee, E., Dideberg, O.
Deposit date:1999-09-28
Release date:2000-05-25
Modification date:2013-01-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of the Penicillin-Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance.
J.Mol.Biol., 299, 2000
1QMF
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1qmf
PENICILLIN-BINDING PROTEIN 2X (PBP-2X) ACYL-ENZYME COMPLEX
Descriptor:PENICILLIN-BINDING PROTEIN 2X
Authors:Gordon, E.J., Mouz, N., Duee, E., Dideberg, O.
Deposit date:1999-09-28
Release date:2000-05-25
Modification date:2013-04-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Crystal Structure of the Penicillin Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance
J.Mol.Biol., 299, 2000
1RP5
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1rp5
PBP2X FROM STREPTOCOCCUS PNEUMONIAE STRAIN 5259 WITH REDUCED SUSCEPTIBILITY TO BETA-LACTAM ANTIBIOTICS
Descriptor:penicillin-binding protein 2x (E.C.3.4.-.-.)
Authors:Pernot, L., Chesnel, L., Legouellec, A., Croize, J., Vernet, T., Dideberg, O., Dessen, A.
Deposit date:2003-12-03
Release date:2004-02-03
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:A PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics.
J.Biol.Chem., 279, 2004
2WAD
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2wad
PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN 5204)
Descriptor:PENICILLIN-BINDING PROTEIN 2B (E.C.3.4.-.-)
Authors:Contreras-Martel, C., Dahout-Gonzalez, C., Dos-Santos-Martins, A., Kotnik, M., Dessen, A.
Deposit date:2009-02-05
Release date:2009-02-24
Modification date:2014-02-19
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci
J.Mol.Biol., 387, 2009
2WAE
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2wae
PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN 5204)
Descriptor:PENICILLIN-BINDING PROTEIN 2B (E.C.3.4.-.-)
Authors:Contreras-Martel, C., Dahout-Gonzalez, C., Dos-Santos-Martins, A., Kotnik, M., Dessen, A.
Deposit date:2009-02-05
Release date:2009-02-24
Modification date:2014-02-19
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci
J.Mol.Biol., 387, 2009
2WAF
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2waf
PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN R6)
Descriptor:PENICILLIN-BINDING PROTEIN 2B (E.C.3.4.-.-)
Authors:Contreras-Martel, C., Dahout-Gonzalez, C., Dos-Santos-Martins, A., Kotnik, M., Dessen, A.
Deposit date:2009-02-05
Release date:2009-02-24
Modification date:2014-02-19
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci
J.Mol.Biol., 387, 2009
2Z2L
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2z2l
PENICILLIN-BINDING PROTEIN 2X (PBP2X) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:Penicillin-binding protein 2X
Authors:Yamada, M., Watanabe, T., Takeuchi, Y.
Deposit date:2007-05-23
Release date:2007-09-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structure of Cefditoren Complexed with Streptococcus pneumoniae Penicillin-Binding Protein 2X: Structural Basis for its High Antimicrobial Activity
Antimicrob.Agents Chemother., 51, 2007
2Z2M
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2z2m
CEFDITOREN-ACYLATED PENICILLIN-BINDING PROTEIN 2X (PBP2X) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:Penicillin-binding protein 2X
Authors:Yamada, M., Watanabe, T., Takeuchi, Y.
Deposit date:2007-05-23
Release date:2007-09-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Cefditoren Complexed with Streptococcus pneumoniae Penicillin-Binding Protein 2X: Structural Basis for its High Antimicrobial Activity
Antimicrob.Agents Chemother., 51, 2007
2ZC3
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2zc3
PENICILLIN-BINDING PROTEIN 2X (PBP 2X) ACYL-ENZYME COMPLEX (BIAPENEM) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:Penicillin-binding protein 2X
Authors:Yamada, M., Watanabe, T., Takeuchi, Y.
Deposit date:2007-11-02
Release date:2008-04-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniae
Antimicrob.Agents Chemother., 52, 2008
2ZC4
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2zc4
PENICILLIN-BINDING PROTEIN 2X (PBP 2X) ACYL-ENZYME COMPLEX (TEBIPENEM) FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:Penicillin-binding protein 2X
Authors:Yamada, M., Watanabe, T., Takeuchi, Y.
Deposit date:2007-11-02
Release date:2008-04-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniae
Antimicrob.Agents Chemother., 52, 2008
3EQU
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3equ
CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 2 FROM NEISSERIA GONORRHOEAE
Descriptor:Penicillin-binding protein 2 (E.C.3.4.16.4)
Authors:Powell, A.J., Deacon, A.M., Nicholas, R.A., Davies, C.
Deposit date:2008-10-01
Release date:2008-10-21
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance.
J.Biol.Chem., 284, 2009
3EQV
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3eqv
CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 2 FROM NEISSERIA GONORRHOEAE CONTAINING FOUR MUTATIONS ASSOCIATED WITH PENICILLIN RESISTANCE
Descriptor:Penicillin-binding protein 2 (E.C.3.4.16.4)
Authors:Powell, A.J., Deacon, A.M., Nicholas, R.A., Davies, C.
Deposit date:2008-10-01
Release date:2008-10-21
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance.
J.Biol.Chem., 284, 2009
3OC2
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3oc2
CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA
Descriptor:Penicillin-binding protein 3
Authors:Sainsbury, S., Bird, L., Stuart, D.I., Owens, R.J., Ren, J., Oxford Protein Production Facility (OPPF)
Deposit date:2010-08-09
Release date:2010-11-10
Modification date:2014-03-26
Method:X-RAY DIFFRACTION (1.968 Å)
Cite:Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms
J.Mol.Biol., 405, 2011
3OCL
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3ocl
CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH CARBENICILLIN
Descriptor:Penicillin-binding protein 3
Authors:Sainsbury, S., Bird, L., Stuart, D.I., Owens, R.J., Ren, J., Oxford Protein Production Facility (OPPF)
Deposit date:2010-08-10
Release date:2010-11-10
Modification date:2014-03-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms
J.Mol.Biol., 405, 2011
3OCN
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3ocn
CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH CEFTAZIDIME
Descriptor:penicillin-binding protein 3
Authors:Sainsbury, S., Bird, L., Stuart, D.I., Owens, R.J., Ren, J., Oxford Protein Production Facility (OPPF)
Deposit date:2010-08-10
Release date:2010-11-10
Modification date:2014-03-26
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms
J.Mol.Biol., 405, 2011
3PBN
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3pbn
CRYSTAL STRUCTURE OF APO PBP3 FROM PSEUDOMONAS AERUGINOSA
Descriptor:Penicillin-binding protein 3
Authors:Han, S.
Deposit date:2010-10-20
Release date:2010-12-22
Modification date:2011-01-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 107, 2010
3PBO
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3pbo
CRYSTAL STRUCTURE OF PBP3 COMPLEXED WITH CEFTAZIDIME
Descriptor:Penicillin-binding protein 3
Authors:Han, S.
Deposit date:2010-10-20
Release date:2010-12-22
Modification date:2011-01-05
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 107, 2010
3PBQ
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3pbq
CRYSTAL STRUCTURE OF PBP3 COMPLEXED WITH IMIPENEM
Descriptor:Penicillin-binding protein 3
Authors:Han, S.
Deposit date:2010-10-20
Release date:2010-12-22
Modification date:2011-08-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 107, 2010
3PBR
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3pbr
CRYSTAL STRUCTURE OF PBP3 COMPLEXED WITH MEROPENEM
Descriptor:Penicillin-binding protein 3
Authors:Han, S.
Deposit date:2010-10-20
Release date:2010-12-22
Modification date:2012-05-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 107, 2010
3PBS
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3pbs
CRYSTAL STRUCTURE OF PBP3 COMPLEXED WITH AZTREONAM
Descriptor:Penicillin-binding protein 3
Authors:Han, S.
Deposit date:2010-10-20
Release date:2010-12-22
Modification date:2011-08-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 107, 2010
3PBT
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3pbt
CRYSTAL STRUCTURE OF PBP3 COMPLEXED WITH MC-1
Descriptor:Penicillin-binding protein 3
Authors:Han, S., Evdokimov, A.
Deposit date:2010-10-20
Release date:2010-12-22
Modification date:2012-02-08
Method:X-RAY DIFFRACTION (1.641 Å)
Cite:Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 107, 2010
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