8GHG
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8GHF
| cryo-EM structure of hSlo1 in plasma membrane vesicles | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL, ... | Authors: | Tao, X, Zhao, C, MacKinnon, R. | Deposit date: | 2023-03-10 | Release date: | 2023-05-10 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Membrane protein isolation and structure determination in cell-derived membrane vesicles. Proc.Natl.Acad.Sci.USA, 120, 2023
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8GH9
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8HKK
| ion channel | Descriptor: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | Authors: | Jiang, D.H, Zhang, J.T. | Deposit date: | 2022-11-27 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HKM
| ion channel | Descriptor: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION, ... | Authors: | Jiang, D.H, Zhang, J.T. | Deposit date: | 2022-11-27 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HKQ
| ion channel | Descriptor: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | Authors: | Jiang, D.H, Zhang, J.T. | Deposit date: | 2022-11-27 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HK6
| potassium channel | Descriptor: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION | Authors: | Jiang, D.H, Zhang, J.T. | Deposit date: | 2022-11-25 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HKF
| ion channel | Descriptor: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION | Authors: | Jiang, D.H, Zhang, Z.T. | Deposit date: | 2022-11-25 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HIR
| potassium channels | Descriptor: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | Authors: | Jiang, D.H, Zhang, J.T. | Deposit date: | 2022-11-21 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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7YO3
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7YO2
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7YO1
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7YO0
| Cryo-EM structure of human Slo1-LRRC26 complex with Symmetry Expansion | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Calcium-activated potassium channel subunit alpha-1, ... | Authors: | Yamanouchi, D, Nureki, O. | Deposit date: | 2022-08-01 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for dual allosteric gating modulation of Slo1-LRRC channel complex To Be Published
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7YO5
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7YNZ
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7YO4
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7PXH
| Emodepside-bound Drosophila Slo channel | Descriptor: | (3~{S},6~{R},9~{S},12~{R},15~{S},18~{R},21~{S},24~{R})-4,6,10,16,18,22-hexamethyl-3,9,15,21-tetrakis(2-methylpropyl)-12,24-bis[(4-morpholin-4-ylphenyl)methyl]-1,7,13,19-tetraoxa-4,10,16,22-tetrazacyclotetracosane-2,5,8,11,14,17,20,23-octone, (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, ... | Authors: | Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S. | Deposit date: | 2021-10-08 | Release date: | 2021-12-15 | Last modified: | 2021-12-22 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM. Nat Commun, 12, 2021
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7PXG
| Verruculogen-bound Drosophila Slo channel | Descriptor: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ... | Authors: | Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S. | Deposit date: | 2021-10-08 | Release date: | 2021-12-15 | Last modified: | 2021-12-22 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM. Nat Commun, 12, 2021
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7PXF
| Ca2+ free Drosophila Slo channel | Descriptor: | Isoform J of Calcium-activated potassium channel slowpoke, MAGNESIUM ION, POTASSIUM ION | Authors: | Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S. | Deposit date: | 2021-10-08 | Release date: | 2021-12-15 | Last modified: | 2021-12-22 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM. Nat Commun, 12, 2021
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7PXE
| Ca2+ bound Drosophila Slo channel | Descriptor: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ... | Authors: | Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S. | Deposit date: | 2021-10-08 | Release date: | 2021-12-15 | Last modified: | 2021-12-22 | Method: | ELECTRON MICROSCOPY (2.38 Å) | Cite: | Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM. Nat Commun, 12, 2021
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7RK6
| Aplysia Slo1 with Barium | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BARIUM ION, BK channel, ... | Authors: | Zhu, J, Srivastava, S, Cachau, R, Holmgren, M. | Deposit date: | 2021-07-22 | Release date: | 2022-06-22 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (2.91 Å) | Cite: | CryoEM structure of Aplysia Slo1 with 0 mM Ba2+ at 2.91 A To Be Published
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7RJT
| Aplysia Slo1 with Barium | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BARIUM ION, BK channel, ... | Authors: | Zhu, J, Srivastava, S, Cachau, R, Holmgren, M. | Deposit date: | 2021-07-21 | Release date: | 2022-06-22 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | CryoEM structure of Aplysia Slo1 with 10 mM Ba2+ at 2.93 A To Be Published
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6V5A
| Crystal structure of the human BK channel gating ring L390P mutant | Descriptor: | CALCIUM ION, Calcium-activated potassium channel subunit alpha-1, SULFATE ION | Authors: | Deng, Z, Yuan, P. | Deposit date: | 2019-12-03 | Release date: | 2020-07-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Coupling of Ca2+and voltage activation in BK channels through the alpha B helix/voltage sensor interface. Proc.Natl.Acad.Sci.USA, 117, 2020
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6V3G
| Cryo-EM structure of Ca2+-free hsSlo1 channel | Descriptor: | Calcium-activated potassium channel subunit alpha-1 | Authors: | Tao, X, MacKinnon, R. | Deposit date: | 2019-11-25 | Release date: | 2019-12-25 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Molecular structures of the human Slo1 K + channel in complex with beta 4. Elife, 8, 2019
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6V35
| Cryo-EM structure of Ca2+-free hsSlo1-beta4 channel complex | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | Authors: | Tao, X, MacKinnon, R. | Deposit date: | 2019-11-25 | Release date: | 2019-12-25 | Last modified: | 2020-10-07 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular structures of the human Slo1 K + channel in complex with beta 4. Elife, 8, 2019
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