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1L9L
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BU of 1l9l by Molmil
GRANULYSIN FROM HUMAN CYTOLYTIC T LYMPHOCYTES
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ETHANOL, Granulysin, ...
Authors:Anderson, D.H, Sawaya, M.R, Cascio, D, Ernst, W, Krensky, A, Modlin, R, Eisenberg, D.
Deposit date:2002-03-25
Release date:2002-11-06
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Granulysin Crystal Structure and a Structure-Derived Lytic Mechanism
J.Mol.Biol., 325, 2002
3BQP
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BU of 3bqp by Molmil
Crystal Structure of Human Saposin D (orthorhombic)
Descriptor: MAGNESIUM ION, Proactivator polypeptide
Authors:Prive, G.G, Popovic, K.
Deposit date:2007-12-20
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structures of the human ceramide activator protein saposin D.
Acta Crystallogr.,Sect.D, 64, 2008
5U85
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BU of 5u85 by Molmil
Murine saposin-D (SapD), open conformation
Descriptor: Saposin-D
Authors:Gebai, A, Gorelik, A, Illes, K, Nagar, B.
Deposit date:2016-12-13
Release date:2018-06-13
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of saposin D in an open conformation.
J. Struct. Biol., 204, 2018
5W7D
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BU of 5w7d by Molmil
Murine acyloxyacyl hydrolase (AOAH), S262A mutant
Descriptor: 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorelik, A, Illes, K, Nagar, B.
Deposit date:2017-06-19
Release date:2018-01-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the mammalian lipopolysaccharide detoxifier.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6VZ0
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BU of 6vz0 by Molmil
C-terminal domain of mouse surfactant protein B crystallized at high pH
Descriptor: Pulmonary surfactant-associated protein B, ZINC ION
Authors:Rapoport, T.A, Bodnar, N.O.
Deposit date:2020-02-27
Release date:2020-11-25
Last modified:2021-01-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mechanism of Lamellar Body Formation by Lung Surfactant Protein B.
Mol.Cell, 81, 2021
4UEX
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BU of 4uex by Molmil
Structure of human Saposin A at lysosomal pH
Descriptor: PROSAPOSIN
Authors:Hill, C.H, Read, R.J, Deane, J.E.
Deposit date:2014-12-20
Release date:2015-07-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Human Saposin a at Lysosomal Ph.
Acta Crystallogr.,Sect.D, 71, 2015
5W7E
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BU of 5w7e by Molmil
Murine acyloxyacyl hydrolase (AOAH), S262A mutant, with dimyristoyl phosphatidylcholine
Descriptor: (2S)-3-hydroxypropane-1,2-diyl ditetradecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acyloxyacyl hydrolase, ...
Authors:Gorelik, A, Illes, K, Nagar, B.
Deposit date:2017-06-19
Release date:2018-01-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structure of the mammalian lipopolysaccharide detoxifier.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6VZD
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BU of 6vzd by Molmil
N-terminal domain of mouse surfactant protein B (K46E/R51E mutant) with bound lipid
Descriptor: (7Z,19R,22R)-25-amino-22-hydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphapentacos-7-en-19-yl (9Z)-octadec-9-enoate, Pulmonary surfactant-associated protein B
Authors:Rapoport, T.A, Bodnar, N.O.
Deposit date:2020-02-28
Release date:2020-11-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Mechanism of Lamellar Body Formation by Lung Surfactant Protein B.
Mol.Cell, 81, 2021
5W7B
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BU of 5w7b by Molmil
Rabbit acyloxyacyl hydrolase (AOAH), proteolytically processed, S262A mutant, with LPS
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorelik, A, Illes, K, Nagar, B.
Deposit date:2017-06-19
Release date:2018-01-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the mammalian lipopolysaccharide detoxifier.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6VZE
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BU of 6vze by Molmil
C-terminal domain of mouse surfactant protein B crystallized at low pH
Descriptor: Pulmonary surfactant-associated protein B, SULFATE ION
Authors:Rapoport, T.A, Bodnar, N.O.
Deposit date:2020-02-28
Release date:2020-11-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of Lamellar Body Formation by Lung Surfactant Protein B.
Mol.Cell, 81, 2021
4DDJ
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BU of 4ddj by Molmil
Crystal structure of saposin A in complex with lauryldimethylamine-N-oxide (LDAO)
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, Saposin-A
Authors:Popovic, K, Prive, G.G.
Deposit date:2012-01-18
Release date:2012-02-15
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of saposin A lipoprotein discs.
Proc.Natl.Acad.Sci.USA, 109, 2012
3RFI
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BU of 3rfi by Molmil
Crystal structure of the saposin-like domain of plant aspartic protease from Solanum tuberosum
Descriptor: Asp
Authors:Bhaumik, P, Wlodawer, A.
Deposit date:2011-04-06
Release date:2011-06-15
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Mechanism of the Saposin-like Domain of a Plant Aspartic Protease.
J.Biol.Chem., 286, 2011
3BQQ
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BU of 3bqq by Molmil
Crystal Structure of Human Saposin D (triclinic)
Descriptor: PROACTIVATOR POLYPEPTIDE
Authors:Prive, G.G, Popovic, K.
Deposit date:2007-12-20
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the human ceramide activator protein saposin D.
Acta Crystallogr.,Sect.D, 64, 2008
2DOB
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BU of 2dob by Molmil
Crystal Structure of Human Saposin A
Descriptor: CALCIUM ION, Proactivator polypeptide
Authors:Prive, G.G, Ahn, V.E.
Deposit date:2006-04-28
Release date:2006-07-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of saposins A and C.
Protein Sci., 15, 2006
2RB3
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BU of 2rb3 by Molmil
Crystal Structure of Human Saposin D
Descriptor: GLYCEROL, Proactivator polypeptide, SULFATE ION
Authors:Maier, T, Rossman, M, Saenger, W.
Deposit date:2007-09-18
Release date:2008-04-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
4V2O
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BU of 4v2o by Molmil
Structure of saposin B in complex with chloroquine
Descriptor: N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE, SAPOSIN-B
Authors:Zubieta, C, Lai, X, Doyle, R.P.
Deposit date:2014-10-13
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:The Lysosomal Protein Saposin B Binds Chloroquine.
Chemmedchem, 11, 2016
7MBK
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BU of 7mbk by Molmil
N-terminal domain of mouse surfactant protein B, 6W mutant
Descriptor: Pulmonary surfactant-associated protein B
Authors:Milicic, G, Rapoport, T.A.
Deposit date:2021-03-31
Release date:2021-04-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Mechanism of Lamellar Body Formation by Lung Surfactant Protein B.
Mol.Cell, 81, 2021
6VYN
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BU of 6vyn by Molmil
N-terminal domain of mouse surfactant protein B with bound lipid, wild type
Descriptor: (7Z,19R,22R)-25-amino-22-hydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphapentacos-7-en-19-yl (9Z)-octadec-9-enoate, Pulmonary surfactant-associated protein B
Authors:Rapoport, T.A, Bodnar, N.O.
Deposit date:2020-02-27
Release date:2020-11-25
Last modified:2021-01-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of Lamellar Body Formation by Lung Surfactant Protein B.
Mol.Cell, 81, 2021
1N69
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BU of 1n69 by Molmil
Crystal structure of human saposin B
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, SAPOSIN B
Authors:Ahn, V.E, Faull, K.F, Whitelegge, J.P, Fluharty, A.L, Prive, G.G.
Deposit date:2002-11-08
Release date:2003-01-07
Last modified:2021-06-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of saposin B reveals a dimeric shell for lipid binding
Proc.Natl.Acad.Sci.USA, 100, 2003
1QDM
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BU of 1qdm by Molmil
CRYSTAL STRUCTURE OF PROPHYTEPSIN, A ZYMOGEN OF A BARLEY VACUOLAR ASPARTIC PROTEINASE.
Descriptor: PROPHYTEPSIN
Authors:Kervinen, J, Tobin, G.J, Costa, J, Waugh, D.S, Wlodawer, A, Zdanov, A.
Deposit date:1999-05-19
Release date:1999-07-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of plant aspartic proteinase prophytepsin: inactivation and vacuolar targeting.
EMBO J., 18, 1999
5W7A
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BU of 5w7a by Molmil
Rabbit acyloxyacyl hydrolase (AOAH), proteolytically processed, S262A mutant, with LPS (low quality saposin domain)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-HYDROXY-TETRADECANOIC ACID, ...
Authors:Gorelik, A, Illes, K, Nagar, B.
Deposit date:2017-06-19
Release date:2018-01-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the mammalian lipopolysaccharide detoxifier.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6W1B
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BU of 6w1b by Molmil
N-terminal domain of mouse surfactant protein B with bound lipid, Y59A/H79A mutant
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Pulmonary surfactant-associated protein B
Authors:Rapoport, T.A, Bodnar, N.O.
Deposit date:2020-03-04
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Mechanism of Lamellar Body Formation by Lung Surfactant Protein B.
Mol.Cell, 81, 2021
6SLR
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BU of 6slr by Molmil
Structure of saposin B in complex with atovaquone
Descriptor: 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, GLYCEROL, Prosaposin
Authors:Zubieta, C, Milliken, B, Doyle, R.
Deposit date:2019-08-20
Release date:2020-09-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure of saposin B in complex with atovaquone
To Be Published
2GTG
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BU of 2gtg by Molmil
Crystal Structure of Human Saposin C
Descriptor: Proactivator polypeptide
Authors:Prive, G.G, Ahn, V.E.
Deposit date:2006-04-28
Release date:2006-07-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of saposins A and C.
Protein Sci., 15, 2006
2QYP
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BU of 2qyp by Molmil
Orthorhombic Crystal Structure of Human Saposin C Dimer in Open Conformation
Descriptor: Proactivator polypeptide
Authors:Rossmann, M, Saenger, W, Maier, T.
Deposit date:2007-08-15
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008

 

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