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1NKL
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NK-LYSIN FROM PIG, NMR, 20 STRUCTURES
Descriptor: NK-LYSIN
Authors:Otting, G, Liepinsh, E.
Deposit date:1997-04-17
Release date:1997-06-16
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Saposin fold revealed by the NMR structure of NK-lysin.
Nat.Struct.Biol., 4, 1997
1QDM
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BU of 1qdm by Molmil
CRYSTAL STRUCTURE OF PROPHYTEPSIN, A ZYMOGEN OF A BARLEY VACUOLAR ASPARTIC PROTEINASE.
Descriptor: PROPHYTEPSIN
Authors:Kervinen, J, Tobin, G.J, Costa, J, Waugh, D.S, Wlodawer, A, Zdanov, A.
Deposit date:1999-05-19
Release date:1999-07-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of plant aspartic proteinase prophytepsin: inactivation and vacuolar targeting.
EMBO J., 18, 1999
1L9L
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GRANULYSIN FROM HUMAN CYTOLYTIC T LYMPHOCYTES
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ETHANOL, Granulysin, ...
Authors:Anderson, D.H, Sawaya, M.R, Cascio, D, Ernst, W, Krensky, A, Modlin, R, Eisenberg, D.
Deposit date:2002-03-25
Release date:2002-11-06
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Granulysin Crystal Structure and a Structure-Derived Lytic Mechanism
J.Mol.Biol., 325, 2002
1N69
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Crystal structure of human saposin B
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, SAPOSIN B
Authors:Ahn, V.E, Faull, K.F, Whitelegge, J.P, Fluharty, A.L, Prive, G.G.
Deposit date:2002-11-08
Release date:2003-01-07
Last modified:2021-06-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of saposin B reveals a dimeric shell for lipid binding
Proc.Natl.Acad.Sci.USA, 100, 2003
1M12
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BU of 1m12 by Molmil
NMR solution structure of human Saposin C
Descriptor: SAPOSIN C
Authors:de Alba, E, Weiler, S, Tjandra, N.
Deposit date:2002-06-17
Release date:2003-07-29
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of human saposin C: pH-dependent interaction with phospholipid vesicles.
Biochemistry, 42, 2003
1OF9
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Solution structure of the pore forming toxin of entamoeba histolytica (Amoebapore A)
Descriptor: PORE-FORMING PEPTIDE AMEOBAPORE A
Authors:Hecht, O, Schleinkofer, K, Bruhn, H, Leippe, M, Van Nuland, N, Dingley, A.J, Grotzinger, J.
Deposit date:2003-04-09
Release date:2004-02-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the Pore-Forming Protein of Entamoeba Histolytica
J.Biol.Chem., 279, 2004
1SN6
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NMR solution structure of human Saposin C in SDS micelles
Descriptor: Proactivator polypeptide
Authors:Hawkins, C.A, de Alba, E, Tjandra, N.
Deposit date:2004-03-10
Release date:2005-03-01
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of human saposin C in a detergent environment.
J.Mol.Biol., 346, 2005
2GTG
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Crystal Structure of Human Saposin C
Descriptor: Proactivator polypeptide
Authors:Prive, G.G, Ahn, V.E.
Deposit date:2006-04-28
Release date:2006-07-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of saposins A and C.
Protein Sci., 15, 2006
2DOB
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BU of 2dob by Molmil
Crystal Structure of Human Saposin A
Descriptor: CALCIUM ION, Proactivator polypeptide
Authors:Prive, G.G, Ahn, V.E.
Deposit date:2006-04-28
Release date:2006-07-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of saposins A and C.
Protein Sci., 15, 2006
3BQP
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Crystal Structure of Human Saposin D (orthorhombic)
Descriptor: MAGNESIUM ION, Proactivator polypeptide
Authors:Prive, G.G, Popovic, K.
Deposit date:2007-12-20
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structures of the human ceramide activator protein saposin D.
Acta Crystallogr.,Sect.D, 64, 2008
3BQQ
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Crystal Structure of Human Saposin D (triclinic)
Descriptor: PROACTIVATOR POLYPEPTIDE
Authors:Prive, G.G, Popovic, K.
Deposit date:2007-12-20
Release date:2008-02-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the human ceramide activator protein saposin D.
Acta Crystallogr.,Sect.D, 64, 2008
2QYP
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BU of 2qyp by Molmil
Orthorhombic Crystal Structure of Human Saposin C Dimer in Open Conformation
Descriptor: Proactivator polypeptide
Authors:Rossmann, M, Saenger, W, Maier, T.
Deposit date:2007-08-15
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2R0R
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BU of 2r0r by Molmil
Crystal Structure of Human Saposin D variant SapD K9E
Descriptor: Proactivator polypeptide, SULFATE ION
Authors:Rossmann, M, Saenger, W, Maier, T.
Deposit date:2007-08-21
Release date:2008-04-29
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2Z9A
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BU of 2z9a by Molmil
Crystal Structure of Human Saposin C Dimer in Open Conformation
Descriptor: GLYCEROL, Proactivator polypeptide
Authors:Rossmann, M, Saenger, W, Maier, T.
Deposit date:2007-09-18
Release date:2008-04-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2R1Q
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Crystal Structure of Iodinated Human Saposin D in Space Group C2221
Descriptor: Proactivator polypeptide
Authors:Maier, T, Rossman, M, Saenger, W.
Deposit date:2007-08-23
Release date:2008-04-29
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2RB3
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BU of 2rb3 by Molmil
Crystal Structure of Human Saposin D
Descriptor: GLYCEROL, Proactivator polypeptide, SULFATE ION
Authors:Maier, T, Rossman, M, Saenger, W.
Deposit date:2007-09-18
Release date:2008-04-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2JSA
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BU of 2jsa by Molmil
Solution structure of Caenopore-5 (81 Pro Trans confomer)
Descriptor: Saposin-like protein family protein 5
Authors:Mysliwy, J, Grotzinger, J.
Deposit date:2007-07-02
Release date:2008-10-14
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Caenopore-5: the three-dimensional structure of an antimicrobial protein from Caenorhabditis elegans.
Dev.Comp.Immunol., 34, 2010
2JS9
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Structure of caenopore-5 (81 Pro cis conformer)
Descriptor: Saposin-like protein family protein 5
Authors:Mysliwy, J, Grotzinger, J.
Deposit date:2007-07-02
Release date:2008-10-14
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Caenopore-5: the three-dimensional structure of an antimicrobial protein from Caenorhabditis elegans.
Dev.Comp.Immunol., 34, 2010
3RFI
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BU of 3rfi by Molmil
Crystal structure of the saposin-like domain of plant aspartic protease from Solanum tuberosum
Descriptor: Asp
Authors:Bhaumik, P, Wlodawer, A.
Deposit date:2011-04-06
Release date:2011-06-15
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Mechanism of the Saposin-like Domain of a Plant Aspartic Protease.
J.Biol.Chem., 286, 2011
4DDJ
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BU of 4ddj by Molmil
Crystal structure of saposin A in complex with lauryldimethylamine-N-oxide (LDAO)
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, Saposin-A
Authors:Popovic, K, Prive, G.G.
Deposit date:2012-01-18
Release date:2012-02-15
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of saposin A lipoprotein discs.
Proc.Natl.Acad.Sci.USA, 109, 2012
4UEX
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BU of 4uex by Molmil
Structure of human Saposin A at lysosomal pH
Descriptor: PROSAPOSIN
Authors:Hill, C.H, Read, R.J, Deane, J.E.
Deposit date:2014-12-20
Release date:2015-07-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Human Saposin a at Lysosomal Ph.
Acta Crystallogr.,Sect.D, 71, 2015
4V2O
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BU of 4v2o by Molmil
Structure of saposin B in complex with chloroquine
Descriptor: N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE, SAPOSIN-B
Authors:Zubieta, C, Lai, X, Doyle, R.P.
Deposit date:2014-10-13
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:The Lysosomal Protein Saposin B Binds Chloroquine.
Chemmedchem, 11, 2016
5NXB
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Mouse galactocerebrosidase in complex with saposin A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Graham, S.C, Hill, C.H, Deane, J.E.
Deposit date:2017-05-09
Release date:2017-05-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The mechanism of glycosphingolipid degradation revealed by a GALC-SapA complex structure.
Nat Commun, 9, 2018
5W7E
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Murine acyloxyacyl hydrolase (AOAH), S262A mutant, with dimyristoyl phosphatidylcholine
Descriptor: (2S)-3-hydroxypropane-1,2-diyl ditetradecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acyloxyacyl hydrolase, ...
Authors:Gorelik, A, Illes, K, Nagar, B.
Deposit date:2017-06-19
Release date:2018-01-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structure of the mammalian lipopolysaccharide detoxifier.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5W7A
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Rabbit acyloxyacyl hydrolase (AOAH), proteolytically processed, S262A mutant, with LPS (low quality saposin domain)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-HYDROXY-TETRADECANOIC ACID, ...
Authors:Gorelik, A, Illes, K, Nagar, B.
Deposit date:2017-06-19
Release date:2018-01-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the mammalian lipopolysaccharide detoxifier.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

 

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