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3L5W
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BU of 3l5w by Molmil
Crystal structure of the complex between IL-13 and C836 FAB
Descriptor: C836 HEAVY CHAIN, C836 LIGHT CHAIN, GLYCEROL, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2009-12-22
Release date:2010-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human framework adaptation of a mouse anti-human IL-13 antibody.
J.Mol.Biol., 398, 2010
7REW
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BU of 7rew by Molmil
Crystal Structure of IL-13 in complex with MMAb3 Fab
Descriptor: IL13, anti-cyno interleukin 13 Fab heavy chain, anti-cyno interleukin 13 Fab light chain
Authors:Sudom, A, Min, X.
Deposit date:2021-07-13
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Development of a potent high-affinity human therapeutic antibody via novel application of recombination signal sequence-based affinity maturation.
J.Biol.Chem., 298, 2022
8BLQ
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BU of 8blq by Molmil
Cryo-EM structure of the CODV-IL13-RefAb triple complex
Descriptor: CODV-Fab, heavy chain, light chain, ...
Authors:Fernandez-Martinez, D, Kandiah, E.
Deposit date:2022-11-10
Release date:2023-06-07
Method:ELECTRON MICROSCOPY (3.97 Å)
Cite:Structural insights into the bi-specific cross-over dual variable antibody architecture by cryo-EM.
Sci Rep, 13, 2023
4I77
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BU of 4i77 by Molmil
Lebrikizumab Fab bound to IL-13
Descriptor: Interleukin-13, Lebrikizumab heavy chain, Lebrikizumab light chain
Authors:Eigenbrot, C, Ultsch, M.
Deposit date:2012-11-30
Release date:2013-02-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis of Signaling Blockade by Anti-IL-13 Antibody Lebrikizumab.
J.Mol.Biol., 425, 2013
1GA3
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BU of 1ga3 by Molmil
NMR STRUCTURE OF INTERLEUKIN-13
Descriptor: Interleukin-13
Authors:Eisenmesser, E.Z, Horita, D.A, Altieri, A.S, Byrd, R.A.
Deposit date:2000-11-29
Release date:2001-07-04
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of interleukin-13 and insights into receptor engagement
J.Mol.Biol., 310, 2001
4PS4
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BU of 4ps4 by Molmil
Crystal structure of the complex between IL-13 and M1295 FAB
Descriptor: Interleukin-13, M1295 HEAVY CHAIN, M1295 LIGHT CHAIN
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2014-03-06
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human Framework Adaptation of a Mouse Anti-Human Il-13 Antibody.
J.Mol.Biol., 398, 2010
5KNH
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BU of 5knh by Molmil
CRYSTAL STRUCTURE OF DARPIN 6G9 IN COMPLEX WITH CYNO IL-13
Descriptor: ACETATE ION, DARPIN 6G9, IL13
Authors:Teplyakov, A, Malia, T, Obmolova, G, Gilliland, G.
Deposit date:2016-06-28
Release date:2016-12-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Conformational flexibility of an anti-IL-13 DARPin.
Protein Eng. Des. Sel., 30, 2017
5L6Y
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BU of 5l6y by Molmil
il13 in complex with tralokinumab
Descriptor: FORMIC ACID, Interleukin-13, tralokinumab FAb digest VH, ...
Authors:Breed, J.
Deposit date:2016-06-01
Release date:2016-12-21
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13R alpha 1 and IL-13R alpha 2.
J. Mol. Biol., 429, 2017
1IJZ
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BU of 1ijz by Molmil
Solution Structure of Human IL-13
Descriptor: INTERLEUKIN-13
Authors:Moy, F.J, Diblasio, E, Wilhelm, J, Powers, R.
Deposit date:2001-05-01
Release date:2002-05-01
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of human IL-13 and implication for receptor binding.
J.Mol.Biol., 310, 2001
1IK0
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BU of 1ik0 by Molmil
Solution Structure of Human IL-13
Descriptor: INTERLEUKIN-13
Authors:Moy, F.J, Diblasio, E, Wilhelm, J, Powers, R.
Deposit date:2001-05-01
Release date:2002-05-01
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of human IL-13 and implication for receptor binding.
J.Mol.Biol., 310, 2001
3G6D
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BU of 3g6d by Molmil
Crystal structure of the complex between CNTO607 Fab and IL-13
Descriptor: CNTO607 Fab Heavy chain, CNTO607 Fab Light chain, Interleukin-13, ...
Authors:Teplyakov, A, Obmolova, G, Gilliland, G.L.
Deposit date:2009-02-06
Release date:2009-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Epitope mapping of anti-interleukin-13 neutralizing antibody CNTO607.
J.Mol.Biol., 389, 2009
3L5X
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BU of 3l5x by Molmil
Crystal structure of the complex between IL-13 and H2L6 FAB
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, H2L6 HEAVY CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2009-12-22
Release date:2010-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Human framework adaptation of a mouse anti-human IL-13 antibody.
J.Mol.Biol., 398, 2010
3BPO
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BU of 3bpo by Molmil
Crystal structure of the IL13-IL4R-IL13Ra ternary complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin 13, ...
Authors:Garcia, K.C.
Deposit date:2007-12-18
Release date:2008-02-05
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Cell(Cambridge,Mass.), 132, 2008
5E4E
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BU of 5e4e by Molmil
Engineered Interleukin-13 bound to receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-13, Interleukin-13 receptor subunit alpha-1, ...
Authors:Moraga, I, Thomas, C, Jude, K.M, Garcia, K.C.
Deposit date:2015-10-05
Release date:2015-12-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.
Sci.Signal., 8, 2015
3LB6
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BU of 3lb6 by Molmil
The structure of IL-13 in complex with IL-13Ralpha2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Interleukin-13, ...
Authors:Lupardus, P.J, Garcia, K.C, Birnbaum, M.E.
Deposit date:2010-01-07
Release date:2010-03-16
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Molecular basis for shared cytokine recognition revealed in the structure of an unusually high affinity complex between IL-13 and IL-13Ralpha2.
Structure, 18, 2010

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