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2CEX
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Structure of a sialic acid binding protein (SiaP) in the presence of the sialic acid acid analogue Neu5Ac2en
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, GLYCEROL, PROTEIN HI0146, ...
Authors:Muller, A, Severi, E, Mulligan, C, Watts, A.G, Kelly, D.J, Wilson, K.S, Wilkinson, A.J, Thomas, G.H.
Deposit date:2006-02-10
Release date:2006-05-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conservation of Structure and Mechanism in Primary and Secondary Transporters Exemplified by Siap, a Sialic Acid Binding Virulence Factor from Haemophilus Influenzae
J.Biol.Chem., 281, 2006
2CEY
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Apo Structure of SiaP
Descriptor: PROTEIN HI0146, ZINC ION
Authors:Muller, A, Severi, E, Mulligan, C, Watts, A.G, Kelly, D.J, Wilson, K.S, Wilkinson, A.J, Thomas, G.H.
Deposit date:2006-02-11
Release date:2006-05-15
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conservation of Structure and Mechanism in Primary and Secondary Transporters Exemplified by Siap, a Sialic Acid Binding Virulence Factor from Haemophilus Influenzae
J.Biol.Chem., 281, 2006
2HPG
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The crystal structure of a thermophilic TRAP periplasmic binding protein
Descriptor: ABC transporter, periplasmic substrate-binding protein
Authors:Cuneo, M.J, Hellinga, H.W.
Deposit date:2006-07-17
Release date:2007-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of a periplasmic binding protein in the tripartite ATP-independent transporter family reveals a tetrameric assembly that may have a role in ligand transport.
J.Biol.Chem., 283, 2008
2HZK
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Crystal structures of a sodium-alpha-keto acid binding subunit from a TRAP transporter in its open form
Descriptor: GLYCEROL, TRAP-T family sorbitol/mannitol transporter, periplasmic binding protein, ...
Authors:Gonin, S, Arnoux, P, Pierru, B, Alonso, B, Sabaty, M, Pignol, D.
Deposit date:2006-08-09
Release date:2007-04-03
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of an Extracytoplasmic Solute Receptor from a TRAP transporter in its open and closed forms reveal a helix-swapped dimer requiring a cation for alpha-keto acid binding.
Bmc Struct.Biol., 7, 2007
2HZL
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Crystal structures of a sodium-alpha-keto acid binding subunit from a TRAP transporter in its closed forms
Descriptor: PYRUVIC ACID, SODIUM ION, TRAP-T family sorbitol/mannitol transporter, ...
Authors:Gonin, S, Arnoux, P, Pierru, B, Alonso, B, Sabaty, M, Pignol, D.
Deposit date:2006-08-09
Release date:2007-04-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structures of an Extracytoplasmic Solute Receptor from a TRAP transporter in its open and closed forms reveal a helix-swapped dimer requiring a cation for alpha-keto acid binding.
Bmc Struct.Biol., 7, 2007
2PFY
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Crystal structure of DctP7, a Bordetella pertussis extracytoplasmic solute receptor binding pyroglutamic acid
Descriptor: PYROGLUTAMIC ACID, Putative exported protein
Authors:Rucktooa, P.
Deposit date:2007-04-06
Release date:2007-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structures of two Bordetella pertussis Periplasmic Receptors Contribute to Defining a Novel Pyroglutamic Acid Binding DctP Subfamily.
J.Mol.Biol., 370, 2007
2PFZ
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Crystal structure of DctP6, a Bordetella pertussis extracytoplasmic solute receptor binding pyroglutamic acid
Descriptor: PYROGLUTAMIC ACID, Putative exported protein
Authors:Rucktooa, P.
Deposit date:2007-04-06
Release date:2007-06-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of two Bordetella pertussis Periplasmic Receptors Contribute to Defining a Novel Pyroglutamic Acid Binding DctP Subfamily.
J.Mol.Biol., 370, 2007
2V4C
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Structure of sialic acid binding protein (SiaP) in the presence of KDN
Descriptor: SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP, deamino-beta-neuraminic acid
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2008-09-18
Release date:2010-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Water networks can determine the affinity of ligand binding to proteins.
J.Am.Chem.Soc., 2019
2VPN
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High-resolution structure of the periplasmic ectoine-binding protein from TeaABC TRAP-transporter of Halomonas elongata
Descriptor: (4S)-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, MAGNESIUM ION, PERIPLASMIC SUBSTRATE BINDING PROTEIN
Authors:Kuhlmann, S.I, Terwisscha van Scheltinga, A.C, Bienert, R, Kunte, H.J, Ziegler, C.
Deposit date:2008-03-03
Release date:2008-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:1.55 A Structure of the Ectoine Binding Protein Teaa of the Osmoregulated Trap-Transporter Teaabc from Halomonas Elongata.
Biochemistry, 47, 2008
2VPO
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High resolution structure of the periplasmic binding protein TeaA from TeaABC TRAP transporter of Halomonas elongata in complex with hydroxyectoine
Descriptor: (4S,5S)-5-HYDROXY-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, MAGNESIUM ION, PERIPLASMIC SUBSTRATE BINDING PROTEIN
Authors:Kuhlmann, S.I, Terwisscha van Scheltinga, A.C, Bienert, R, Kunte, H.J, Ziegler, C.
Deposit date:2008-03-03
Release date:2008-08-26
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:1.55 A Structure of the Ectoine Binding Protein Teaa of the Osmoregulated Trap-Transporter Teaabc from Halomonas Elongata.
Biochemistry, 47, 2008
2WX9
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Crystal structure of the sialic acid binding periplasmic protein SiaP
Descriptor: N-glycolyl-beta-neuraminic acid, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2009-11-05
Release date:2011-01-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Water networks can determine the affinity of ligand binding to proteins.
J.Am.Chem.Soc., 2019
2WYK
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SiaP in complex with Neu5Gc
Descriptor: N-glycolyl-beta-neuraminic acid, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP, THIOCYANATE ION
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2009-11-16
Release date:2011-01-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Water networks can determine the affinity of ligand binding to proteins.
J.Am.Chem.Soc., 2019
2WYP
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BU of 2wyp by Molmil
Crystal structure of sialic acid binding protein
Descriptor: SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP, deamino-beta-neuraminic acid
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2009-11-18
Release date:2011-01-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Water networks can determine the affinity of ligand binding to proteins.
J.Am.Chem.Soc., 2019
2XA5
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BU of 2xa5 by Molmil
Structure of substrate binding protein SiaP (A11N) in complex with Neu5Ac
Descriptor: N-acetyl-beta-neuraminic acid, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2010-03-26
Release date:2011-04-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Water networks can determine the affinity of ligand binding to proteins.
J.Am.Chem.Soc., 2019
2XWI
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SiaP R147K mutant in complex with Neu5Ac
Descriptor: N-acetyl-beta-neuraminic acid, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2010-11-04
Release date:2011-11-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.195 Å)
Cite:Tripartite ATP-Independent Periplasmic (Trap) Transporters Use an Arginine-Mediated Selectivity Filter for High Affinity Substrate Binding.
J.Biol.Chem., 290, 2015
2XWK
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SiaP R147A mutant in complex with Neu5Ac
Descriptor: N-acetyl-beta-neuraminic acid, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2010-11-04
Release date:2011-11-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Tripartite ATP-Independent Periplasmic (Trap) Transporters Use an Arginine-Mediated Selectivity Filter for High Affinity Substrate Binding.
J.Biol.Chem., 290, 2015
2XWO
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SiaP R147E mutant in complex with sialylamide
Descriptor: (2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxamide, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2010-11-04
Release date:2011-11-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Tripartite ATP-Independent Periplasmic (Trap) Transporters Use an Arginine-Mediated Selectivity Filter for High Affinity Substrate Binding.
J.Biol.Chem., 290, 2015
2XWV
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SiaP complex
Descriptor: N-acetyl-beta-neuraminic acid, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2010-11-05
Release date:2011-11-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Tripartite ATP-Independent Periplasmic (Trap) Transporters Use an Arginine-Mediated Selectivity Filter for High Affinity Substrate Binding.
J.Biol.Chem., 290, 2015
2XXK
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SiaP complex
Descriptor: N-acetyl-beta-neuraminic acid, SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2010-11-10
Release date:2011-11-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Siap Complex
To be Published
2ZZV
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Crystal Structure of a Periplasmic Substrate Binding Protein in Complex with Calcium and Lactate
Descriptor: ABC transporter, solute-binding protein, CALCIUM ION, ...
Authors:Akiyama, N, Takeda, K, Miki, K.
Deposit date:2009-02-27
Release date:2009-08-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of a periplasmic substrate-binding protein in complex with calcium lactate
J.Mol.Biol., 392, 2009
2ZZW
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Crystal Structure of a Periplasmic Substrate Binding Protein in Complex with Zinc and Lactate
Descriptor: ABC transporter, solute-binding protein, LACTIC ACID, ...
Authors:Akiyama, N, Takeda, K, Miki, K.
Deposit date:2009-02-27
Release date:2009-08-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of a periplasmic substrate-binding protein in complex with calcium lactate
J.Mol.Biol., 392, 2009
2ZZX
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Crystal Structure of a Periplasmic Substrate Binding Protein in Complex with Lactate
Descriptor: ABC transporter, solute-binding protein, CALCIUM ION, ...
Authors:Akiyama, N, Takeda, K, Miki, K.
Deposit date:2009-02-27
Release date:2009-08-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of a periplasmic substrate-binding protein in complex with calcium lactate
J.Mol.Biol., 392, 2009
3B50
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Structure of H. influenzae sialic acid binding protein bound to Neu5Ac.
Descriptor: N-acetyl-beta-neuraminic acid, Sialic acid-binding periplasmic protein siaP
Authors:Ramaswamy, S, Coussens, N.P, Apicella, M.A, Johnston, J.W.
Deposit date:2007-10-25
Release date:2007-11-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Characterization of the N-Acetyl-5-neuraminic Acid-binding Site of the Extracytoplasmic Solute Receptor (SiaP) of Nontypeable Haemophilus influenzae Strain 2019
J.Biol.Chem., 283, 2008
3FXB
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Crystal structure of the ectoine-binding protein UehA
Descriptor: (4S)-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, TRAP dicarboxylate transporter, DctP subunit
Authors:Lecher, J, Pittelkow, M, Bursy, J, Smits, S.H.J, Schmitt, L, Bremer, E.
Deposit date:2009-01-20
Release date:2009-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of UehA in complex with ectoine-A comparison with other TRAP-T binding proteins.
J.Mol.Biol., 389, 2009
3GYY
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The ectoine binding protein of the TeaABC TRAP transporter TeaA in the Apo-State
Descriptor: Periplasmic substrate binding protein, ZINC ION
Authors:Kuhlmann, S.I, Terwisscha Van Scheltinga, A.C, Ziegler, C.
Deposit date:2009-04-06
Release date:2010-04-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Evidence for an allosteric mechanism of substrate release from membrane-transporter accessory binding proteins
Proc.Natl.Acad.Sci.USA, 108, 2011

217705

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