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1AKO
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BU of 1ako by Molmil
EXONUCLEASE III FROM ESCHERICHIA COLI
Descriptor: EXONUCLEASE III
Authors:Mol, C.D, Kuo, C.-F, Thayer, M.M, Cunningham, R.P, Tainer, J.A.
Deposit date:1997-05-26
Release date:1997-08-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and function of the multifunctional DNA-repair enzyme exonuclease III.
Nature, 374, 1995
1BIX
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BU of 1bix by Molmil
THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ABASIC SITES
Descriptor: AP ENDONUCLEASE 1, PLATINUM (II) ION, SAMARIUM (III) ION
Authors:Gorman, M.A, Morera, S, Rothwell, D.G, De La Fortelle, E, Mol, C.D, Tainer, J.A, Hickson, I.D, Freemont, P.S.
Deposit date:1998-06-19
Release date:1999-06-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites.
EMBO J., 16, 1997
1I9Y
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BU of 1i9y by Molmil
CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 5-PHOSPHATASE DOMAIN (IPP5C) OF SPSYNAPTOJANIN
Descriptor: PHOSPHATIDYLINOSITOL PHOSPHATE PHOSPHATASE
Authors:Tsujishita, Y, Guo, S, Stolz, L, York, J.D, Hurley, J.H.
Deposit date:2001-03-21
Release date:2001-05-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase.
Cell(Cambridge,Mass.), 105, 2001
1I9Z
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BU of 1i9z by Molmil
CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 5-PHOSPHATASE DOMAIN (IPP5C) OF SPSYNAPTOJANIN IN COMPLEX WITH INOSITOL (1,4)-BISPHOSPHATE AND CALCIUM ION
Descriptor: CALCIUM ION, D-MYO-INOSITOL-1,4-BISPHOSPHATE, PHOSPHATIDYLINOSITOL PHOSPHATE PHOSPHATASE
Authors:Tsujishita, Y, Guo, S, Stolz, L, York, J.D, Hurley, J.H.
Deposit date:2001-03-21
Release date:2001-05-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase.
Cell(Cambridge,Mass.), 105, 2001
2O3H
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BU of 2o3h by Molmil
Crystal structure of the human C65A Ape
Descriptor: ACETATE ION, DNA-(apurinic or apyrimidinic site) lyase, SAMARIUM (III) ION
Authors:Georgiadis, M.M, Gaur, R.K, Delaplane, S, Svenson, J.
Deposit date:2006-12-01
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
Mutat.Res., 643, 2008
2O3C
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BU of 2o3c by Molmil
Crystal structure of zebrafish Ape
Descriptor: APEX nuclease 1, LEAD (II) ION
Authors:Georgiadis, M.M, Gaur, R.K, Delaplane, S, Svenson, J.
Deposit date:2006-12-01
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
Mutat.Res., 643, 2008
1VYB
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BU of 1vyb by Molmil
Endonuclease domain of human LINE1 ORF2p
Descriptor: GLYCEROL, ORF2 CONTAINS A REVERSE TRANSCRIPTASE DOMAIN, SULFATE ION, ...
Authors:Weichenrieder, O, Repanas, K, Perrakis, A.
Deposit date:2004-04-25
Release date:2004-06-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the targeting endonuclease of the human LINE-1 retrotransposon.
Structure, 12, 2004
3DNI
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BU of 3dni by Molmil
CRYSTALLOGRAPHIC REFINEMENT AND STRUCTURE OF DNASE I AT 2 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, DEOXYRIBONUCLEASE I, alpha-D-galactopyranose-(1-6)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Oefner, C, Suck, D.
Deposit date:1992-08-20
Release date:1994-01-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic refinement and structure of DNase I at 2 A resolution.
J.Mol.Biol., 192, 1986
7TR7
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BU of 7tr7 by Molmil
APE1 product complex with abasic ssDNA
Descriptor: DNA (5'-D(P*(3DR)P*CP*GP*AP*TP*GP*C)-3'), DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION
Authors:Freudenthal, B.D, Hoitsma, N.M.
Deposit date:2022-01-28
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanistic insight into AP-endonuclease 1 cleavage of abasic sites at stalled replication fork mimics.
Nucleic Acids Res., 51, 2023
4LND
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BU of 4lnd by Molmil
Crystal structure of human apurinic/apyrimidinic endonuclease 1 with essential Mg2+ cofactor
Descriptor: DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION
Authors:Manvilla, B.A, Pozharski, E, Toth, E.A, Drohat, A.C.
Deposit date:2013-07-11
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg(2+) cofactor.
Acta Crystallogr.,Sect.D, 69, 2013
4PUQ
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BU of 4puq by Molmil
Mus Musculus Tdp2 reaction product complex with 5'-phosphorylated RNA/DNA, glycerol, and Mg2+
Descriptor: ACETATE ION, DNA/RNA hybrid, GLYCEROL, ...
Authors:Schellenberg, M.J, Williams, R.S.
Deposit date:2014-03-13
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2DNA and Top2RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2).
J.Biol.Chem., 289, 2014
2V0R
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BU of 2v0r by Molmil
crystal structure of a hairpin exchange variant (LTx) of the targeting LINE-1 retrotransposon endonuclease
Descriptor: LTX, SULFATE ION
Authors:Repanas, K, Zingler, N, Layer, L.E, Schumann, G.G, Perrakis, A, Weichenrieder, O.
Deposit date:2007-05-17
Release date:2007-07-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Determinants for DNA Target Structure Selectivity of the Human Line-1 Retrotransposon Endonuclease
Nucleic Acids Res., 35, 2007
2V0S
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BU of 2v0s by Molmil
crystal structure of a hairpin exchange variant (LR1) of the targeting LINE-1 retrotransposon endonuclease
Descriptor: GLYCEROL, LR1, MANGANESE (II) ION, ...
Authors:Repanas, K, Zingler, N, Layer, L.E, Schumann, G.G, Perrakis, A, Weichenrieder, O.
Deposit date:2007-05-17
Release date:2007-07-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Determinants for DNA Target Structure Selectivity of the Human Line-1 Retrotransposon Endonuclease.
Nucleic Acids Res., 35, 2007
2UYR
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BU of 2uyr by Molmil
Crystal structure of Bacillus cereus sphingomyelinase mutant :N57A
Descriptor: MAGNESIUM ION, SPHINGOMYELINASE C
Authors:Oda, M, Tsuge, H, Sakurai, J.
Deposit date:2007-04-12
Release date:2008-05-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Bacillus Cereus Sphingomyelinase Mutant : N57A
To be Published
4QHE
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BU of 4qhe by Molmil
Crystal structure of Mg2+ bound human APE1
Descriptor: 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION
Authors:He, H, Chen, Q, Georgiadis, M.M.
Deposit date:2014-05-28
Release date:2014-11-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.
Biochemistry, 53, 2014
4QH9
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BU of 4qh9 by Molmil
Crystal structure of Mn2+ bound human APE1
Descriptor: 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase, MANGANESE (II) ION
Authors:Chen, Q, He, H, Georgiadis, M.M.
Deposit date:2014-05-27
Release date:2014-11-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.175 Å)
Cite:High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.
Biochemistry, 53, 2014
4QHD
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BU of 4qhd by Molmil
Crystal structure of apo human APE1
Descriptor: 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase
Authors:He, H, Chen, Q, Georgiadis, M.M.
Deposit date:2014-05-28
Release date:2014-11-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.
Biochemistry, 53, 2014
3MPR
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BU of 3mpr by Molmil
Crystal Structure of endonuclease/exonuclease/phosphatase family protein from Bacteroides thetaiotaomicron, Northeast Structural Genomics Consortium Target BtR318A
Descriptor: ACETIC ACID, BROMIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Kuzin, A, Su, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-04-27
Release date:2010-05-26
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Northeast Structural Genomics Consortium Target BtR318A
To be Published
6P94
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BU of 6p94 by Molmil
Human APE1 C65A AP-endonuclease product complex
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Whitaker, A.W, Stark, W.J, Freudenthal, B.D.
Deposit date:2019-06-09
Release date:2020-01-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance.
Mutagenesis, 35, 2020
6P93
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BU of 6p93 by Molmil
Human APE1 K98A AP-endonuclease product complex
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Whitaker, A.W, Stark, W.J, Freudenthal, B.D.
Deposit date:2019-06-09
Release date:2020-01-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance.
Mutagenesis, 35, 2020
2VOA
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BU of 2voa by Molmil
Structure of an AP Endonuclease from Archaeoglobus fulgidus
Descriptor: 5'-D(*CP*GP*GP*CP*TP*AP*CP*CP*GP*CP)-3', 5'-D(*GP*CP*GP*GP*TP*AP*GP*CP*CP*GP)-3', EXODEOXYRIBONUCLEASE III
Authors:Kuettner, E.B, Schmiedel, R, Greiner-Stoffele, T, Strater, N.
Deposit date:2008-02-11
Release date:2008-12-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and Function of the Abasic Site Specificity Pocket of an Ap Endonuclease from Archaeoglobus Fulgidus.
DNA Repair, 8, 2009
3NGO
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BU of 3ngo by Molmil
Crystal structure of the human CNOT6L nuclease domain in complex with poly(A) DNA
Descriptor: 5'-D(*AP*AP*AP*A)-3', CCR4-NOT transcription complex subunit 6-like, MAGNESIUM ION
Authors:Wang, H, Morita, M, Yang, W, Bartlam, M, Yamamoto, T, Rao, Z.
Deposit date:2010-06-12
Release date:2010-07-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Embo J., 2010
3NGQ
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BU of 3ngq by Molmil
Crystal structure of the human CNOT6L nuclease domain
Descriptor: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, CCR4-NOT transcription complex subunit 6-like, MAGNESIUM ION
Authors:Wang, H, Morita, M, Yang, W, Bartlam, M, Yamamoto, T, Rao, Z.
Deposit date:2010-06-13
Release date:2010-07-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Embo J., 2010
3NGN
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BU of 3ngn by Molmil
Crystal structure of the human CNOT6L nuclease domain in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, CCR4-NOT transcription complex subunit 6-like
Authors:Wang, H, Morita, M, Yang, W, Bartlam, M, Yamamoto, T, Rao, Z.
Deposit date:2010-06-12
Release date:2010-07-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Embo J., 2010
4RUW
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BU of 4ruw by Molmil
The crystal structure of endonuclease/exonuclease/phosphatase from Beutenbergia cavernae DSM 12333
Descriptor: Endonuclease/exonuclease/phosphatase, GLYCEROL, ZINC ION
Authors:Wu, R, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2014-11-23
Release date:2014-12-24
Method:X-RAY DIFFRACTION (1.281 Å)
Cite:The crystal structure of endonuclease/exonuclease/phosphatase from Beutenbergia cavernae DSM 12333
To be Published

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