1F45
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1f45
HUMAN INTERLEUKIN-12
Descriptor:INTERLEUKIN-12 BETA CHAIN COMPLEX WITH INTERLEUKIN-12 ALPHA CHAIN
Authors:Yoon, C., Johnston, S.C., Tang, J., Tobin, J.F., Somers, W.S.
Deposit date:2000-06-07
Release date:2001-06-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12.
EMBO J., 19, 2000
3HMX
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3hmx
CRYSTAL STRUCTURE OF USTEKINUMAB FAB/IL-12 COMPLEX
Descriptor:Interleukin-12 subunit beta, Interleukin-12 subunit alpha, USTEKINUMAB FAB LIGHT CHAIN, USTEKINUMAB FAB HEAVY CHAIN
Authors:Luo, J.
Deposit date:2009-05-29
Release date:2010-06-09
Modification date:2015-07-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the dual recognition of IL-12 and IL-23 by ustekinumab.
J.Mol.Biol., 402, 2010
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