5CFB
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CRYSTAL STRUCTURE OF HUMAN GLYCINE RECEPTOR ALPHA-3 BOUND TO STRYCHNINE
Descriptor:Glycine receptor subunit alpha-3
Authors:Shaffer, P.L., Huang, X., Chen, H.
Deposit date:2015-07-08
Release date:2015-09-30
Modification date:2015-10-21
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Crystal structure of human glycine receptor-alpha 3 bound to antagonist strychnine.
Nature, 526, 2015
3JAD
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STRUCTURE OF ALPHA-1 GLYCINE RECEPTOR BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY, STRYCHNINE-BOUND STATE
Descriptor:zebra fish alpha1 glycine receptor
Authors:Du, J., Lu, W., Wu, S.P., Cheng, Y.F., Gouaux, E.
Deposit date:2015-06-08
Release date:2015-09-09
Modification date:2015-10-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015
3JAE
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STRUCTURE OF ALPHA-1 GLYCINE RECEPTOR BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY, GLYCINE-BOUND STATE
Descriptor:zebra fish alpha1 glycine receptor
Authors:Du, J., Lu, W., Wu, S.P., Cheng, Y.F., Gouaux, E.
Deposit date:2015-06-08
Release date:2015-09-09
Modification date:2015-10-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015
3JAF
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STRUCTURE OF ALPHA-1 GLYCINE RECEPTOR BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY, GLYCINE/IVERMECTIN-BOUND STATE
Descriptor:zebra fish alpha1 glycine receptor
Authors:Du, J., Lu, W., Wu, S.P., Cheng, Y.F., Gouaux, E.
Deposit date:2015-06-08
Release date:2015-09-09
Modification date:2015-10-14
Method:ELECTRON MICROSCOPY (3.801 Å)
Cite:Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015
4X5T
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ALPHA 1 GLYCINE RECEPTOR TRANSMEMBRANE STRUCTURE FUSED TO THE EXTRACELLULAR DOMAIN OF GLIC
Descriptor:transmembrane human alpha 1 glycine receptor fused to the extracellular domain of GLIC
Authors:Sauguet, L., Corringer, P.J., Huon, C., Delarue, M.
Deposit date:2014-12-05
Release date:2015-02-25
Modification date:2015-03-18
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Allosteric and hyperekplexic mutant phenotypes investigated on an alpha 1 glycine receptor transmembrane structure.
Proc.Natl.Acad.Sci.USA, 112, 2015
4U90
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GEPHE IN COMPLEX WITH PEG CROSSLINKED GABA RECEPTOR ALPHA3 SUBUNIT DERIVED DIMERIC PEPTIDE
Descriptor:Gephyrin E domain , GABA receptor derived peptide
Authors:Kasaragod, V.B., Maric, H.M., Schindelin, H.
Deposit date:2014-08-05
Release date:2014-12-10
Modification date:2015-02-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors.
Angew.Chem.Int.Ed.Engl., 54, 2015
4TNV
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C. ELEGANS GLUTAMATE-GATED CHLORIDE CHANNEL (GLUCL) IN COMPLEX WITH FAB IN A NON-CONDUCTING CONFORMATION
Descriptor:Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, Mouse monoclonal Fab fragment, heavy chain, Mouse monoclonal Fab fragment, light chain
Authors:Althoff, T., Hibbs, R.E., Banerjee, S., Gouaux, E.
Deposit date:2014-06-05
Release date:2014-08-13
Modification date:2014-09-03
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.
Nature, 512, 2014
4TNW
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C. ELEGANS GLUTAMATE-GATED CHLORIDE CHANNEL (GLUCL) IN COMPLEX WITH FAB AND POPC IN A LIPID-MODULATED CONFORMATION
Descriptor:Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, Mouse monoclonal Fab fragment, heavy chain, Mouse monoclonal Fab fragment, light chain
Authors:Althoff, T., Hibbs, R.E., Banerjee, S., Gouaux, E.
Deposit date:2014-06-05
Release date:2014-08-13
Modification date:2014-09-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.
Nature, 512, 2014
4TK1
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GEPH E IN COMPLEX WITH A GABA RECEPTOR ALPHA3 SUBUNIT DERIVED PEPTIDE IN SPACE GROUP P21212
Descriptor:Gephyrin E domain , GABA receptor alpha3 subunit derived peptide
Authors:Kasaragod, V.B., Maric, H.M., Schindelin, H.
Deposit date:2014-05-25
Release date:2014-12-24
Modification date:2015-02-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of the alternative recruitment of GABAA versus glycine receptors through gephyrin.
Nat Commun, 5, 2014
4TK2
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GEPH E IN COMPLEX WITH A GABA RECEPTOR ALPHA3 SUBUNIT DERIVED PEPTIDE IN SPACE GROUP P61
Descriptor:Gephyrin E domain, GABA Receptor aplha3 subunit peptide
Authors:Kasaragod, V.B., Maric, H.M., Schindelin, H.
Deposit date:2014-05-25
Release date:2014-12-24
Modification date:2015-02-04
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Molecular basis of the alternative recruitment of GABAA versus glycine receptors through gephyrin.
Nat Commun, 5, 2014
4TK3
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GEPH E IN COMPLEX WITH A GABA RECEPTOR ALPHA3 DERIVED DOUBLE MUTANT PEPTIDE IN SPACEGROUP P21212
Descriptor:Gephyrin E domain , GABA receptor alpha3 subunit derived double mutant peptide
Authors:Kasaragod, V.B., Maric, H.M., Schindelin, H.
Deposit date:2014-05-25
Release date:2014-12-24
Modification date:2015-02-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of the alternative recruitment of GABAA versus glycine receptors through gephyrin.
Nat Commun, 5, 2014
4TK4
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GEPHE IN COMPLEX WITH A GABA RECEPTOR ALPHA3 SUBUNIT DERIVED DOUBLE MUTANT PEPTIDE IN SPACE GROUP P61
Descriptor:Gephyrin E domain , GABA receptor aplha3 subunit derived double mutant peptide
Authors:Kasaragod, V.B., Maric, H.M., Schindelin, H.
Deposit date:2014-05-25
Release date:2014-12-24
Modification date:2015-02-04
Method:X-RAY DIFFRACTION (3.601 Å)
Cite:Molecular basis of the alternative recruitment of GABAA versus glycine receptors through gephyrin.
Nat Commun, 5, 2014
4PIR
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X-RAY STRUCTURE OF THE MOUSE SEROTONIN 5-HT3 RECEPTOR
Descriptor:mouse 5-HT3 receptor subunit A, VHH15
Authors:Hassaine, G., Deluz, C., Grasso, L., Wyss, R., Tol, M.B., Hovius, R., Graff, A., Stahlberg, H., Tomizaki, T., Desmyter, A., Moreau, C., Li, X.-D., Poitevin, F., Vogel, H., Nury, H.
Deposit date:2014-05-09
Release date:2014-08-06
Modification date:2014-09-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:X-ray structure of the mouse serotonin 5-HT3 receptor.
Nature, 512, 2014
4PD1
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STRUCTURE OF GEPHYRIN E DOMAIN WITH GLYCINE-BETA RECEPTOR PEPTIDE
Descriptor:E- domain of Gephyrin , Glycine receptor betaloop peptide
Authors:Kasaragod, V.B., Maric, H.M., Schindelin, H.
Deposit date:2014-04-17
Release date:2014-08-27
Modification date:2014-12-03
Method:X-RAY DIFFRACTION (1.975 Å)
Cite:Modulation of gephyrin-glycine receptor affinity by multivalency.
Acs Chem.Biol., 9, 2014
4COF
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CRYSTAL STRUCTURE OF A HUMAN GAMMA-AMINOBUTYRIC ACID RECEPTOR, THE GABA(A)R-BETA3 HOMOPENTAMER
Descriptor:GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3
Authors:Miller, P.S., Aricescu, A.R.
Deposit date:2014-01-28
Release date:2014-06-04
Modification date:2014-08-27
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Crystal Structure of a Human Gabaa Receptor
Nature, 512, 2014
2MAW
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NMR STRUCTURES OF THE ALPHA7 NACHR TRANSMEMBRANE DOMAIN.
Descriptor:CHRNA7-FAM7A fusion protein
Authors:Bondarenko, V., Mowrey, D., Xu, Y., Tang, P.
Deposit date:2013-07-19
Release date:2013-11-13
Modification date:2014-05-07
Method:SOLUTION NMR
Cite:Insights into distinct modulation of alpha 7 and alpha 7 beta 2 nicotinic acetylcholine receptors by the volatile anesthetic isoflurane.
J.Biol.Chem., 288, 2013
2M6I
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PUTATIVE PENTAMERIC OPEN-CHANNEL STRUCTURE OF FULL-LENGTH TRANSMEMBRANE DOMAINS OF HUMAN GLYCINE RECEPTOR ALPHA1 SUBUNIT
Descriptor:Full-Length Transmembrane Domains of Human Glycine Receptor alpha1 Subunit
Authors:Mowrey, D., Cui, T., Jia, Y., Ma, D., Makhov, A.M., Zhang, P., Tang, P., Xu, Y.
Deposit date:2013-03-29
Release date:2013-09-04
Modification date:2013-10-30
Method:SOLUTION NMR
Cite:Open-Channel Structures of the Human Glycine Receptor alpha 1 Full-Length Transmembrane Domain.
Structure, 21, 2013
2M6B
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STRUCTURE OF FULL-LENGTH TRANSMEMBRANE DOMAINS OF HUMAN GLYCINE RECEPTOR ALPHA1 MONOMER SUBUNIT
Descriptor:Full-Length Transmembrane Domains of Human Glycine Receptor alpha1 Subunit
Authors:Mowrey, D., Cui, T., Jia, Y., Ma, D., Makhov, A.M., Zhang, P., Tang, P., Xu, Y.
Deposit date:2013-03-28
Release date:2013-09-04
Modification date:2013-10-30
Method:SOLUTION NMR
Cite:Open-Channel Structures of the Human Glycine Receptor alpha 1 Full-Length Transmembrane Domain.
Structure, 21, 2013
2LLY
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NMR STRUCTURES OF THE TRANSMEMBRANE DOMAINS OF THE NACHR A4 SUBUNIT
Descriptor:Neuronal acetylcholine receptor subunit alpha-4
Authors:Bondarenko, V., Mowrey, D., Tillman, T., Cui, T., Liu, L.T., Xu, Y., Tang, P.
Deposit date:2011-11-18
Release date:2012-03-28
Method:SOLUTION NMR
Cite:NMR structures of the transmembrane domains of the a4b2 nAChR.
Biochim.Biophys.Acta, 1818, 2012
2LM2
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NMR STRUCTURES OF THE TRANSMEMBRANE DOMAINS OF THE ACHR B2 SUBUNIT
Descriptor:Neuronal acetylcholine receptor subunit beta-2
Authors:Bondarenko, V., Mowrey, D., Tillman, T., Cui, T., Liu, L.T., Xu, Y., Tang, P.
Deposit date:2011-11-18
Release date:2012-03-28
Method:SOLUTION NMR
Cite:NMR structures of the transmembrane domains of the a4b2 nAChR.
Biochim.Biophys.Acta, 1818, 2012
2LKG
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WSA MAJOR CONFORMATION
Descriptor:Acetylcholine receptor
Authors:Xu, Y., Mowrey, D., Cui, T., Perez-Aguilar, J.M., Saven, J.G., Eckenhoff, R., Tang, P.
Deposit date:2011-10-11
Release date:2012-01-11
Modification date:2012-02-01
Method:SOLUTION NMR
Cite:NMR structure and dynamics of a designed water-soluble transmembrane domain of nicotinic acetylcholine receptor.
Biochim.Biophys.Acta, 1818, 2011
2LKH
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WSA MINOR CONFORMATION
Descriptor:Acetylcholine receptor
Authors:Xu, Y., Mowrey, D., Cui, T., Perez-Aguilar, J., Saven, J.G., Eckenhoff, R., Tang, P.
Deposit date:2011-10-11
Release date:2012-01-11
Modification date:2012-02-01
Method:SOLUTION NMR
Cite:NMR structure and dynamics of a designed water-soluble transmembrane domain of nicotinic acetylcholine receptor.
Biochim.Biophys.Acta, 1818, 2011
2KSR
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NMR STRUCTURES OF TM DOMAIN OF THE N-ACETYLCHOLINE RECEPTOR B2 SUBUNIT
Descriptor:Neuronal acetylcholine receptor subunit beta-2
Authors:Bondarenko, V., Tillman, T., Xu, Y., Tang, P.
Deposit date:2010-01-12
Release date:2010-06-16
Modification date:2010-06-30
Method:SOLUTION NMR
Cite:NMR structure of the transmembrane domain of the n-acetylcholine receptor beta2 subunit.
Biochim.Biophys.Acta, 1798, 2010
2K58
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NMR STRUCTURES OF THE FIRST TRANSMEMBRANE DOMAIN OF THE NEURONAL ACETYLCHOLINE RECEPTOR BETA 2 SUBUNIT
Descriptor:Neuronal acetylcholine receptor subunit beta-2
Authors:Bondarenko, V., Tang, P., Xu, Y.
Deposit date:2008-06-25
Release date:2008-07-08
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structure of the first transmembrane domain of the neuronal acetylcholine receptor beta 2 subunit
Biophys.J., 92, 2007
2K59
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NMR STRUCTURES OF THE SECOND TRANSMEMBRANE DOMAIN OF THE NEURONAL ACETYLCHOLINE RECEPTOR BETA 2 SUBUNIT
Descriptor:Neuronal acetylcholine receptor subunit beta-2
Authors:Bondarenko, V., Tang, P., Xu, Y., Yushmanov, V.
Deposit date:2008-06-25
Release date:2008-07-08
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:NMR structure and dynamics of the second transmembrane domain of the neuronal acetylcholine receptor beta 2 subunit
Biochemistry, 42, 2003
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