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1AXC
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HUMAN PCNA
Descriptor: P21/WAF1, PCNA
Authors:Gulbis, J.M, Kuriyan, J.
Deposit date:1997-10-14
Release date:1998-01-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA.
Cell(Cambridge,Mass.), 87, 1996
4RJF
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Crystal structure of the human sliding clamp at 2.0 angstrom resolution
Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen
Authors:Kroker, A.J, Bruning, J.B.
Deposit date:2014-10-09
Release date:2015-08-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.0072 Å)
Cite:p21 Exploits Residue Tyr151 as a Tether for High-Affinity PCNA Binding.
Biochemistry, 54, 2015
7WP3
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Crystal structure of the complex of proliferating cell nuclear antigen (PCNA) from Leishmania donovani with 1,5-Bis (4-amidinophenoxy) pentane (PNT) at 2.95 A resolution
Descriptor: 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, Proliferating cell nuclear antigen
Authors:Ahmad, M.I, Yadav, S.P, Singh, P.K, Sharma, P, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2022-01-22
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.954 Å)
Cite:Crystal structure of the complex of proliferating cell nuclear antigen (PCNA) from Leishmania donovani with 1,5-Bis (4-amidinophenoxy) pentane (PNT) at 2.95 A resolution
To Be Published
7BUP
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BU of 7bup by Molmil
Crystal structure of PCNA from pathogenic yeast Candida albicans
Descriptor: Proliferating cell nuclear antigen
Authors:sundaram, R, Vasudevan, D.
Deposit date:2020-04-07
Release date:2021-02-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analyses of PCNA from the fungal pathogen Candida albicans identify three regions with species-specific conformations.
Febs Lett., 595, 2021
4HK1
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Crystal Structure of PCNA from Drosophila melanogaster
Descriptor: Proliferating cell nuclear antigen
Authors:Wang, K, Shi, Z.B, Zhou, Z.C.
Deposit date:2012-10-14
Release date:2013-04-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structure of PCNA from Drosophila melanogaster.
Acta Crystallogr.,Sect.F, 69, 2013
1GE8
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PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) HOMOLOG FROM PYROCOCCUS FURIOSUS
Descriptor: PROLIFERATION CELL NUCLEAR ANTIGEN
Authors:Matsumiya, S, Ishino, Y, Morikawa, K.
Deposit date:2000-10-18
Release date:2001-01-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of an archaeal DNA sliding clamp: proliferating cell nuclear antigen from Pyrococcus furiosus.
Protein Sci., 10, 2001
6VVO
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Structure of the human clamp loader (Replication Factor C, RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen, PCNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Gaubitz, C, Liu, X, Stone, N.P, Kelch, B.A.
Deposit date:2020-02-18
Release date:2020-02-26
Last modified:2020-03-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism
Biorxiv, 2020
6WAC
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FF248-249AA PCNA mutant defective in BIR
Descriptor: Proliferating cell nuclear antigen
Authors:Ripley, B.M, Washington, M.T.
Deposit date:2020-03-25
Release date:2020-09-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural analysis of PCNA mutant proteins defective in BIR, FF248-249AA and R80A
To be Published
4L60
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Structure of C81R Mutant PCNA Protein Defective in Mismatch Repair
Descriptor: Proliferating cell nuclear antigen
Authors:Washington, T, Boehm, E.
Deposit date:2013-06-11
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Distinct structural alterations in proliferating cell nuclear antigen block DNA mismatch repair.
Biochemistry, 52, 2013
4L6P
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Structure of C22Y Mutant PCNA protein defective in DNA mismatch repair
Descriptor: GLYCEROL, Proliferating cell nuclear antigen
Authors:Washington, T, Boehm, E.
Deposit date:2013-06-12
Release date:2014-10-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Distinct structural alterations in proliferating cell nuclear antigen block DNA mismatch repair.
Biochemistry, 52, 2013
7O1F
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PCNA from Chaetomium thermophilum in complex with PolD4 PIP peptide
Descriptor: Peptide fragment from PolD4, Proliferating cell nuclear antigen, SODIUM ION
Authors:Alphey, M.A, MacNeill, S, Yang, D.
Deposit date:2021-03-29
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Non-canonical binding of the Chaetomium thermophilum PolD4 N-terminal PIP motif to PCNA involves Q-pocket and compact 2-fork plug interactions but no 3 10 helix.
Febs J., 290, 2023
7O1E
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Crystal structure of PCNA from Chaetomium thermophilum
Descriptor: Proliferating cell nuclear antigen
Authors:Alphey, M.A, MacNeill, S, Yang, D.
Deposit date:2021-03-29
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Non-canonical binding of the Chaetomium thermophilum PolD4 N-terminal PIP motif to PCNA involves Q-pocket and compact 2-fork plug interactions but no 3 10 helix.
Febs J., 290, 2023
2NTI
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Crystal structure of PCNA123 heterotrimer.
Descriptor: 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, BROMIDE ION, DNA polymerase sliding clamp A, ...
Authors:Hlinkova, V, Ling, H.
Deposit date:2006-11-07
Release date:2007-12-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
2OD8
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BU of 2od8 by Molmil
Structure of a peptide derived from Cdc9 bound to PCNA
Descriptor: DNA ligase I, mitochondrial precursor, Proliferating cell nuclear antigen
Authors:Chapados, B.R, Tainer, J.A.
Deposit date:2006-12-21
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase.
Nucleic Acids Res., 35, 2007
4CS5
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Crystal Structure of PCNA from Litopenaeus vannamei
Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN
Authors:Carrasco-Miranda, J.S, Lopez-Zavala, A.A, De-La-Mora, E, Rudino-Pinera, E, Brieba, L.G, Sotelo-Mundo, R.R.
Deposit date:2014-03-04
Release date:2014-04-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of the Shrimp Proliferating Cell Nuclear Antigen: Structural Complementarity with Wssv DNA Polymerase Pip-Box.
Plos One, 9, 2014
4D2G
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BU of 4d2g by Molmil
Crystal structure of human PCNA in complex with p15 peptide
Descriptor: P15, PROLIFERATING CELL NUCLEAR ANTIGEN
Authors:DeBiasio, A, Ibanez, A, Mortuza, G, Molina, R, Cordeiro, T.N, Castillo, F, Villate, M, Merino, N, Lelli, M, Diercks, T, Luque, I, Bernardo, P, Montoya, G, Blanco, F.J.
Deposit date:2014-05-09
Release date:2015-03-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair.
Nat.Commun., 6, 2015
1IZ4
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Pyrococcus furiosus PCNA mutant (Met73Leu/Asp143Ala): tetragonal form
Descriptor: Proliferating cell nuclear antigen
Authors:Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K.
Deposit date:2002-09-21
Release date:2003-04-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA
PROTEIN SCI., 12, 2003
7EFA
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BU of 7efa by Molmil
Crystal structure of the complex between the C-terminal domain of mouse MUTYH and human PCNA
Descriptor: Adenine DNA glycosylase, Proliferating cell nuclear antigen
Authors:Nakamura, T, Nakabeppu, Y, Yamagata, Y.
Deposit date:2021-03-21
Release date:2021-06-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer.
Nucleic Acids Res., 49, 2021
4YHR
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BU of 4yhr by Molmil
Crystal Structure of Yeast Proliferating Cell Nuclear Antigen
Descriptor: Proliferating cell nuclear antigen
Authors:Litman, J.M, Nguyen, V.Q, Kondratick, C.M, Powers, K.T, Schnieders, M.J, Washington, M.T.
Deposit date:2015-02-27
Release date:2015-03-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9502 Å)
Cite:Dead-End Elimination with a Polarizable Force Field Repacks PCNA Models from Low-Resolution X-ray Diffraction into Atomic Resolution Structures
To be published
1ISQ
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Pyrococcus furiosus PCNA complexed with RFCL PIP-box peptide
Descriptor: Proliferating Cell Nuclear Antigen, replication factor C large subunit
Authors:Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K.
Deposit date:2001-12-19
Release date:2002-10-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Physical interaction between proliferating cell nuclear antigen and replication factor C from Pyrococcus furiosus
Genes Cells, 7, 2002
1IZ5
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Pyrococcus furiosus PCNA mutant (Met73Leu, Asp143Ala, Asp147Ala): orthorhombic form
Descriptor: Proliferating cell nuclear antigen
Authors:Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K.
Deposit date:2002-09-23
Release date:2003-04-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA
PROTEIN SCI., 12, 2003
7EP8
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Crystal structure of PCNA from Neurospora crassa
Descriptor: Proliferating cell nuclear antigen
Authors:Sundaram, R, Vasudevan, D.
Deposit date:2021-04-26
Release date:2021-06-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Interdomain connecting loop and J loop structures determine cross-species compatibility of PCNA.
J.Biol.Chem., 297, 2021
4ZTD
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Crystal Structure of Human PCNA in complex with a TRAIP peptide
Descriptor: ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen
Authors:Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A.
Deposit date:2015-05-14
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.
J.Cell Biol., 212, 2016
5A6D
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Proliferating Cell Nuclear Antigen, PCNA, from Thermococcus gammatolerans
Descriptor: DNA POLYMERASE SLIDING CLAMP
Authors:Venancio-Landeros, A, Cardona-Felix, C.S, Rudino-Pinera, E.
Deposit date:2015-06-25
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Cloning, recombinant production and crystallographic structure of Proliferating Cell Nuclear Antigen from radioresistant archaeon Thermococcus gammatolerans.
Biochem Biophys Rep, 8, 2016
7KC0
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Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a primer/template and the PCNA clamp
Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*CP*AP*TP*GP*AP*TP*TP*AP*CP*GP*AP*AP*TP*TP*GP*C)-3'), ...
Authors:Zheng, F, Georgescu, R, Li, H, O'Donnell, M.E.
Deposit date:2020-10-04
Release date:2020-12-02
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of eukaryotic DNA polymerase delta bound to the PCNA clamp while encircling DNA.
Proc.Natl.Acad.Sci.USA, 117, 2020

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