1AHM
 
 | | DER F 2, THE MAJOR MITE ALLERGEN FROM DERMATOPHAGOIDES FARINAE, NMR, 10 STRUCTURES | | Descriptor: | DER F 2 | | Authors: | Ichikawa, S, Hatanaka, H, Yuuki, T, Iwamoto, N, Ogura, K, Okumura, Y, Inagaki, F. | | Deposit date: | 1997-04-07 | | Release date: | 1998-04-08 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | Solution structure of Der f 2, the major mite allergen for atopic diseases.
J.Biol.Chem., 273, 1998
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1AHK
 | | DER F 2, THE MAJOR MITE ALLERGEN FROM DERMATOPHAGOIDES FARINAE, NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | DER F 2 | | Authors: | Ichikawa, S, Hatanaka, H, Yuuki, T, Iwamoto, N, Ogura, K, Okumura, Y, Inagaki, F. | | Deposit date: | 1997-04-07 | | Release date: | 1998-04-08 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | Solution structure of Der f 2, the major mite allergen for atopic diseases.
J.Biol.Chem., 273, 1998
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1A9V
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1G13
 | | HUMAN GM2 ACTIVATOR STRUCTURE | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GANGLIOSIDE M2 ACTIVATOR PROTEIN | | Authors: | Wright, C.S, Li, S.C, Rastinejad, F. | | Deposit date: | 2000-10-10 | | Release date: | 2001-04-11 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of human GM2-activator protein with a novel beta-cup topology.
J.Mol.Biol., 304, 2000
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1KTJ
 | | X-ray Structure Of Der P 2, The Major House Dust Mite Allergen | | Descriptor: | ALLERGEN DER P 2 | | Authors: | Derewenda, U, Li, J, Derewenda, Z, Dauter, Z, Mueller, G.A, Rule, G.S, Benjamin, D.C. | | Deposit date: | 2002-01-16 | | Release date: | 2002-05-15 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | The crystal structure of a major dust mite allergen Der p 2, and its biological implications.
J.Mol.Biol., 318, 2002
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1NEP
 | | Crystal Structure Analysis of the Bovine NPC2 (Niemann-Pick C2) Protein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Epididymal secretory protein E1, PHOSPHATE ION | | Authors: | Friedland, N, Liou, H.-L, Lobel, P, Stock, A.M. | | Deposit date: | 2002-12-11 | | Release date: | 2003-01-28 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of a Cholesterol-binding Protein Deficient in Niemann-Pick Type C2 Disease
Proc.Natl.Acad.Sci.USA, 100, 2003
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1PU5
 | | GM2-activator Protein crystal structure | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ganglioside GM2 activator | | Authors: | Wright, C.S, Zhao, Q, Rastinejad, F. | | Deposit date: | 2003-06-24 | | Release date: | 2004-06-29 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural analysis of lipid complexes of GM2-activator protein.
J.Mol.Biol., 331, 2003
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1PUB
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1TJJ
 | | Human GM2 Activator Protein PAF complex | | Descriptor: | (2R)-2-(acetyloxy)-3-(hexadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Wright, C.S, Mi, L.-Z, Rastinejad, F. | | Deposit date: | 2004-06-04 | | Release date: | 2004-12-07 | | Last modified: | 2013-10-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Evidence for lipid packaging in the crystal structure of the GM2-activator complex with platelet activating factor
J.Mol.Biol., 342, 2004
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1WRF
 | | Refined solution structure of Der f 2, The Major Mite Allergen from Dermatophagoides farinae | | Descriptor: | Mite group 2 allergen Der f 2 | | Authors: | Ichikawa, S, Takai, T, Inoue, T, Yuuki, T, Okumura, Y, Ogura, K, Inagaki, F, Hatanaka, H. | | Deposit date: | 2004-10-15 | | Release date: | 2005-04-19 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | NMR Study on the Major Mite Allergen Der f 2: Its Refined Tertiary Structure, Epitopes for Monoclonal Antibodies and Characteristics Shared by ML Protein Group Members
J.Biochem.(Tokyo), 137, 2005
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1XWV
 | | Structure of the house dust mite allergen Der f 2: Implications for function and molecular basis of IgE cross-reactivity | | Descriptor: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Der f II | | Authors: | Johannessen, B.R, Skov, L.K, Kastrup, J.S, Kristensen, O, Bolwig, C, Larsen, J.N, Spangfort, M, Lund, K, Gajhede, M. | | Deposit date: | 2004-11-02 | | Release date: | 2004-12-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Structure of the house dust mite allergen Der f 2: implications for function and molecular basis of IgE cross-reactivity.
Febs Lett., 579, 2005
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2AF9
 | | Crystal Structure analysis of GM2-Activator protein complexed with phosphatidylcholine | | Descriptor: | Ganglioside GM2 activator, ISOPROPYL ALCOHOL, LAURIC ACID, ... | | Authors: | Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F. | | Deposit date: | 2005-07-25 | | Release date: | 2005-10-25 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
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2AG2
 | | Crystal Structure Analysis of GM2-activator protein complexed with Phosphatidylcholine | | Descriptor: | (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE, 2-(((R)-2,3-DIHYDROXYPROPYL)PHOSPHORYLOXY)-N,N,N-TRIMETHYLETHANAMINIUM, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F. | | Deposit date: | 2005-07-26 | | Release date: | 2005-10-25 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
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2AG9
 | | Crystal Structure of the Y137S mutant of GM2-Activator Protein | | Descriptor: | Ganglioside GM2 activator, ISOPROPYL ALCOHOL, MYRISTIC ACID | | Authors: | Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F. | | Deposit date: | 2005-07-26 | | Release date: | 2005-10-25 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
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2AGC
 | | Crystal Structure of mouse GM2- activator Protein | | Descriptor: | Ganglioside GM2 activator, LAURIC ACID, MYRISTIC ACID | | Authors: | Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F. | | Deposit date: | 2005-07-26 | | Release date: | 2005-10-25 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
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2AG4
 | | Crystal Structure Analysis of GM2-activator protein complexed with phosphatidylcholine | | Descriptor: | (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE, Ganglioside GM2 activator, ISOPROPYL ALCOHOL, ... | | Authors: | Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F. | | Deposit date: | 2005-07-26 | | Release date: | 2005-10-25 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
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2F08
 | | Crystal structure of a major house dust mite allergen, Derf 2 | | Descriptor: | O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, mite allergen Der f II | | Authors: | Mikami, B, Tanaka, Y, Minato, N, Suzuki, M, Korematsu, S. | | Deposit date: | 2005-11-12 | | Release date: | 2005-11-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure and some properties of a major house dust mite allergen, Derf 2
Biochem.Biophys.Res.Commun., 339, 2006
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2HKA
 | | Crystal structure of bovine NPC2 and cholesterol sulfate complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CHOLEST-5-EN-3-YL HYDROGEN SULFATE, ... | | Authors: | Xu, S, Gu, L, Benoff, B, Stock, A.M. | | Deposit date: | 2006-07-03 | | Release date: | 2007-06-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease
J.Biol.Chem., 282, 2007
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2E59
 | | Crystal structure of human MD-2 in complex with lipid IVa | | Descriptor: | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-4-O-phosphono-beta-D-glucopyranose, ... | | Authors: | Ohto, U, Satow, Y. | | Deposit date: | 2006-12-19 | | Release date: | 2007-06-26 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa
Science, 316, 2007
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2E56
 | | Crystal structure of human MD-2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, MYRISTIC ACID | | Authors: | Ohto, U, Satow, Y. | | Deposit date: | 2006-12-19 | | Release date: | 2007-06-26 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa.
Science, 316, 2007
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2Z65
 | | Crystal structure of the human TLR4 TV3 hybrid-MD-2-Eritoran complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-O-DECYL-2-DEOXY-6-O-{2-DEOXY-3-O-[(3R)-3-METHOXYDECYL]-6-O-METHYL-2-[(11Z)-OCTADEC-11-ENOYLAMINO]-4-O-PHOSPHONO-BETA-D-GLUCOPYRANOSYL}-2-[(3-OXOTETRADECANOYL)AMINO]-1-O-PHOSPHONO-ALPHA-D-GLUCOPYRANOSE, Lymphocyte antigen 96, ... | | Authors: | Lee, J.-O, Kim, H.M, Park, B.S. | | Deposit date: | 2007-07-22 | | Release date: | 2007-09-18 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
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3FXI
 | | Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-HYDROXY-TETRADECANOIC ACID, ... | | Authors: | Park, B.S, Song, D.H, Kim, H.M, Lee, J.-O. | | Deposit date: | 2009-01-21 | | Release date: | 2009-03-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
Nature, 458, 2009
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3M7O
 | | Crystal structure of mouse MD-1 in complex with phosphatidylcholine | | Descriptor: | (2S)-3-(octadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, BENZAMIDINE, ... | | Authors: | Harada, H, Ohto, U, Satow, Y. | | Deposit date: | 2010-03-17 | | Release date: | 2010-06-09 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal structure of mouse MD-1 with endogenous phospholipid bound in its cavity
J.Mol.Biol., 400, 2010
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3MTX
 | | Crystal structure of chicken MD-1 | | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, GLYCEROL, Protein MD-1, ... | | Authors: | Yoon, S.I, Hong, M, Han, G.W, Wilson, I.A. | | Deposit date: | 2010-05-01 | | Release date: | 2010-06-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of soluble MD-1 and its interaction with lipid IVa.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3MU3
 | | Crystal structure of chicken MD-1 complexed with lipid IVa | | Descriptor: | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-4-O-phosphono-beta-D-glucopyranose, GLYCEROL, ... | | Authors: | Yoon, S.I, Hong, M, Han, G.W, Wilson, I.A. | | Deposit date: | 2010-05-01 | | Release date: | 2010-06-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of soluble MD-1 and its interaction with lipid IVa.
Proc.Natl.Acad.Sci.USA, 107, 2010
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