1G13
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HUMAN GM2 ACTIVATOR STRUCTURE
Descriptor:GANGLIOSIDE M2 ACTIVATOR PROTEIN
Authors:Wright, C.S., Li, S.C., Rastinejad, F.
Deposit date:2000-10-10
Release date:2001-04-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of human GM2-activator protein with a novel beta-cup topology.
J.Mol.Biol., 304, 2000
1NEP
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CRYSTAL STRUCTURE ANALYSIS OF THE BOVINE NPC2 (NIEMANN-PICK C2) PROTEIN
Descriptor:Epididymal secretory protein E1
Authors:Friedland, N., Liou, H.-L., Lobel, P., Stock, A.M.
Deposit date:2002-12-11
Release date:2003-01-28
Modification date:2011-11-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of a Cholesterol-binding Protein Deficient in Niemann-Pick Type C2 Disease
Proc.Natl.Acad.Sci.USA, 100, 2003
1PU5
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GM2-ACTIVATOR PROTEIN CRYSTAL STRUCTURE
Descriptor:Ganglioside GM2 activator
Authors:Wright, C.S., Zhao, Q., Rastinejad, F.
Deposit date:2003-06-24
Release date:2004-06-29
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of lipid complexes of GM2-activator protein.
J.Mol.Biol., 331, 2003
1PUB
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GM2-ACTIVATOR PROTEIN CRYSTAL STRUCTURE
Descriptor:GM2-activator protein
Authors:Wright, C.S., Zhao, Q., Rastinejad, F.
Deposit date:2003-06-24
Release date:2004-06-29
Modification date:2009-09-01
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural analysis of lipid complexes of GM2-activator protein.
J.Mol.Biol., 331, 2003
1TJJ
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HUMAN GM2 ACTIVATOR PROTEIN PAF COMPLEX
Descriptor:Ganglioside GM2 activator
Authors:Wright, C.S., Mi, L.-Z., Rastinejad, F.
Deposit date:2004-06-04
Release date:2004-12-07
Modification date:2013-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Evidence for lipid packaging in the crystal structure of the GM2-activator complex with platelet activating factor
J.Mol.Biol., 342, 2004
2AF9
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CRYSTAL STRUCTURE ANALYSIS OF GM2-ACTIVATOR PROTEIN COMPLEXED WITH PHOSPHATIDYLCHOLINE
Descriptor:Ganglioside GM2 activator
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-25
Release date:2005-10-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AG2
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CRYSTAL STRUCTURE ANALYSIS OF GM2-ACTIVATOR PROTEIN COMPLEXED WITH PHOSPHATIDYLCHOLINE
Descriptor:Ganglioside GM2 activator
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AG4
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CRYSTAL STRUCTURE ANALYSIS OF GM2-ACTIVATOR PROTEIN COMPLEXED WITH PHOSPHATIDYLCHOLINE
Descriptor:Ganglioside GM2 activator
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AG9
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CRYSTAL STRUCTURE OF THE Y137S MUTANT OF GM2-ACTIVATOR PROTEIN
Descriptor:Ganglioside GM2 activator
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AGC
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CRYSTAL STRUCTURE OF MOUSE GM2- ACTIVATOR PROTEIN
Descriptor:Ganglioside GM2 activator
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2E56
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CRYSTAL STRUCTURE OF HUMAN MD-2
Descriptor:Lymphocyte antigen 96
Authors:Ohto, U., Satow, Y.
Deposit date:2006-12-19
Release date:2007-06-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa.
Science, 316, 2007
2E59
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CRYSTAL STRUCTURE OF HUMAN MD-2 IN COMPLEX WITH LIPID IVA
Descriptor:Lymphocyte antigen 96
Authors:Ohto, U., Satow, Y.
Deposit date:2006-12-19
Release date:2007-06-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa
Science, 316, 2007
2HKA
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CRYSTAL STRUCTURE OF BOVINE NPC2 AND CHOLESTEROL SULFATE COMPLEX
Descriptor:CRYSTAL STRUCTURE OF BOVINE NPC2 AND CHOLESTEROL SULFATE COMPLEX
Authors:Xu, S., Gu, L., Benoff, B., Stock, A.M.
Deposit date:2006-07-03
Release date:2007-06-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease
J.Biol.Chem., 282, 2007
3M7O
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CRYSTAL STRUCTURE OF MOUSE MD-1 IN COMPLEX WITH PHOSPHATIDYLCHOLINE
Descriptor:Lymphocyte antigen 86
Authors:Harada, H., Ohto, U., Satow, Y.
Deposit date:2010-03-17
Release date:2010-06-09
Modification date:2014-01-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of mouse MD-1 with endogenous phospholipid bound in its cavity
J.Mol.Biol., 400, 2010
3MTX
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CRYSTAL STRUCTURE OF CHICKEN MD-1
Descriptor:Protein MD-1
Authors:Yoon, S.I., Hong, M., Han, G.W., Wilson, I.A.
Deposit date:2010-05-01
Release date:2010-06-09
Modification date:2010-07-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of soluble MD-1 and its interaction with lipid IVa.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MU3
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CRYSTAL STRUCTURE OF CHICKEN MD-1 COMPLEXED WITH LIPID IVA
Descriptor:Protein MD-1
Authors:Yoon, S.I., Hong, M., Han, G.W., Wilson, I.A.
Deposit date:2010-05-01
Release date:2010-06-09
Modification date:2010-07-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of soluble MD-1 and its interaction with lipid IVa.
Proc.Natl.Acad.Sci.USA, 107, 2010
3RG1
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CRYSTAL STRUCTURE OF THE RP105/MD-1 COMPLEX
Descriptor:CD180 molecule, LY86 protein
Authors:Yoon, S.I., Hong, M., Wilson, I.A.
Deposit date:2011-04-07
Release date:2011-08-31
Modification date:2011-09-21
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:An unusual dimeric structure and assembly for TLR4 regulator RP105-MD-1.
Nat.Struct.Mol.Biol., 18, 2011
2Z64
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CRYSTAL STRUCTURE OF MOUSE TLR4 AND MOUSE MD-2 COMPLEX
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96
Authors:Lee, J.-O., Kim, H.M., Park, B.S.
Deposit date:2007-07-22
Release date:2007-09-18
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
2Z65
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CRYSTAL STRUCTURE OF THE HUMAN TLR4 TV3 HYBRID-MD-2-ERITORAN COMPLEX
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B, Lymphocyte antigen 96
Authors:Lee, J.-O., Kim, H.M., Park, B.S.
Deposit date:2007-07-22
Release date:2007-09-18
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
3B2D
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CRYSTAL STRUCTURE OF HUMAN RP105/MD-1 COMPLEX
Descriptor:CD180 antigen, Lymphocyte antigen 86
Authors:Ohto, U., Shimizu, T.
Deposit date:2011-07-29
Release date:2011-11-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structures of Mouse and Human RP105/MD-1 Complexes Reveal Unique Dimer Organization of the Toll-Like Receptor Family.
J.Mol.Biol., 413, 2011
3FXI
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CRYSTAL STRUCTURE OF THE HUMAN TLR4-HUMAN MD-2-E.COLI LPS RA COMPLEX
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96
Authors:Park, B.S., Song, D.H., Kim, H.M., Lee, J.-O.
Deposit date:2009-01-21
Release date:2009-03-03
Modification date:2012-06-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
Nature, 458, 2009
3T6Q
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CRYSTAL STRUCTURE OF MOUSE RP105/MD-1 COMPLEX
Descriptor:CD180 antigen, Lymphocyte antigen 86
Authors:Ohto, U., Shimizu, T.
Deposit date:2011-07-28
Release date:2011-11-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structures of Mouse and Human RP105/MD-1 Complexes Reveal Unique Dimer Organization of the Toll-Like Receptor Family.
J.Mol.Biol., 413, 2011
3ULA
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CRYSTAL STRUCTURE OF THE TV3 MUTANT F63W-MD-2-ERITORAN COMPLEX
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B, Lymphocyte antigen 96
Authors:Kim, H.J., Cheong, H.K., Jeon, Y.H.
Deposit date:2011-11-10
Release date:2012-04-04
Modification date:2013-10-09
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
3VQ1
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CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LIPID IVA COMPLEX
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96
Authors:Ohto, U., Shimizu, T.
Deposit date:2012-03-17
Release date:2012-05-09
Modification date:2013-07-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2
Proc.Natl.Acad.Sci.USA, 109, 2012
3VQ2
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CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LPS COMPLEX
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96
Authors:Ohto, U., Shimizu, T.
Deposit date:2012-03-17
Release date:2012-05-09
Modification date:2013-07-17
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2
Proc.Natl.Acad.Sci.USA, 109, 2012
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