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2MFQ
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BU of 2mfq by Molmil
NMR solution structures of FRS2a PTB domain with neurotrophin receptor TrkB
Descriptor: BDNF/NT-3 growth factors receptor, Fibroblast growth factor receptor substrate 2
Authors:Zeng, L, Zhou, M.
Deposit date:2013-10-18
Release date:2014-03-05
Last modified:2014-06-25
Method:SOLUTION NMR
Cite:Structural insights into FRS2 alpha PTB domain recognition by neurotrophin receptor TrkB.
Proteins, 82, 2014
3ML4
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BU of 3ml4 by Molmil
Crystal structure of a complex between Dok7 PH-PTB and the MuSK juxtamembrane region
Descriptor: Muscle, skeletal receptor tyrosine-protein kinase, Protein Dok-7
Authors:Bergamin, E, Hubbard, S.R.
Deposit date:2010-04-16
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Cytoplasmic Adaptor Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization.
Mol.Cell, 39, 2010
5U1M
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BU of 5u1m by Molmil
Structure of the IRS-1 PTB Domain Bound to the Juxtamembrane Region of the Insulin Receptor
Descriptor: Insulin receptor, Insulin receptor substrate 1
Authors:Eck, M.J, Dhe-Paganon, S.
Deposit date:2016-11-28
Release date:2017-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression.
Nat Commun, 8, 2017
2DLW
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BU of 2dlw by Molmil
Solution structure of the IRS domain of human docking protein 2, isoform a
Descriptor: Docking protein 2, isoform a
Authors:Zhang, H.P, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-20
Release date:2006-10-20
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the IRS domain of human docking protein 2, isoform a
to be published
1J0W
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BU of 1j0w by Molmil
Crystal Structure Analysis of the Dok-5 PTB Domain
Descriptor: downstream of tyrosine kinase 5
Authors:Shi, N, Ding, Y, Qiang, B.Q, Yuan, J.G, Rao, Z.H.
Deposit date:2002-11-25
Release date:2003-12-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure Analysis of the Dok-5 PTB Domain
To be Published
1UEF
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BU of 1uef by Molmil
Crystal Structure of Dok1 PTB Domain Complex
Descriptor: 13-mer peptide from Proto-oncogene tyrosine-protein kinase receptor ret, Docking protein 1
Authors:Shi, N, Ye, S, Liu, Y, Zhou, W, Ding, Y, Lou, Z, Qiang, B, Yan, J, Rao, Z.
Deposit date:2003-05-14
Release date:2004-05-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain
J.Biol.Chem., 279, 2004
1P5T
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BU of 1p5t by Molmil
Crystal Structure of Dok1 PTB Domain
Descriptor: Docking protein 1
Authors:Shi, N, Ye, S, Liu, Y, Zhou, W, Ding, Y, Lou, Z, Qiang, B, Yuan, J, Rao, Z.
Deposit date:2003-04-28
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain
J.BIOL.CHEM., 279, 2004
1IRS
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BU of 1irs by Molmil
IRS-1 PTB DOMAIN COMPLEXED WITH A IL-4 RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: IL-4 RECEPTOR PHOSPHOPEPTIDE, IRS-1
Authors:Zhou, M.-M, Huang, B, Olejniczak, E.T, Meadows, R.P, Shuker, S.B, Miyazaki, M, Trub, T, Shoelson, S.E, Feisk, S.W.
Deposit date:1996-03-22
Release date:1997-05-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain.
Nat.Struct.Biol., 3, 1996
1XR0
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BU of 1xr0 by Molmil
Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors
Descriptor: Basic fibroblast growth factor receptor 1, FGFR signalling adaptor SNT-1
Authors:Dhalluin, C, Yan, K.S, Plotnikova, O, Lee, K.W, Zeng, L, Kuti, M, Mujtaba, S, Goldfarb, M.P, Zhou, M.-M.
Deposit date:2004-10-13
Release date:2004-11-02
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors
Mol.Cell, 6, 2000
2KUP
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BU of 2kup by Molmil
Solution structure of the complex of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of HALK
Descriptor: 19-residue peptide from ALK tyrosine kinase receptor, Fibroblast growth factor receptor substrate 3
Authors:Li, H, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2010-02-24
Release date:2010-05-26
Last modified:2014-02-12
Method:SOLUTION NMR
Cite:Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
J.Struct.Funct.Genom., 11, 2010
2KUQ
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BU of 2kuq by Molmil
Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of HALK
Descriptor: Fibroblast growth factor receptor substrate 3,LINKER,ALK tyrosine kinase receptor
Authors:Li, H, Koshiba, S, Tomizawa, T, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2010-02-24
Release date:2010-05-26
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
J.Struct.Funct.Genom., 11, 2010
2V76
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BU of 2v76 by Molmil
Crystal structure of the human dok1 PTB domain
Descriptor: 1,2-ETHANEDIOL, DOCKING PROTEIN 1, GLYCEROL, ...
Authors:Oxley, C.L, Anthis, N.J, Lowe, E.D, Campbell, I.D, Wegener, K.L.
Deposit date:2007-07-26
Release date:2008-01-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:An Integrin Phosphorylation Switch: The Effect of {Beta}3 Integrin Tail Phosphorylation on Dok1 and Talin Binding.
J.Biol.Chem., 283, 2008
2YS5
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BU of 2ys5 by Molmil
Solution structure of the complex of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK
Descriptor: ALK tyrosine kinase receptor, Fibroblast growth factor receptor substrate 3
Authors:Li, H, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-03
Release date:2008-04-08
Last modified:2014-02-12
Method:SOLUTION NMR
Cite:Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
J.Struct.Funct.Genom., 11, 2010
2YT2
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BU of 2yt2 by Molmil
Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK
Descriptor: Fibroblast growth factor receptor substrate 3 and ALK tyrosine kinase receptor
Authors:Li, H, Koshiba, S, Tomizawa, T, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2008-04-08
Last modified:2014-02-12
Method:SOLUTION NMR
Cite:Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
J.Struct.Funct.Genom., 11, 2010
1QQG
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BU of 1qqg by Molmil
CRYSTAL STRUCTURE OF THE PH-PTB TARGETING REGION OF IRS-1
Descriptor: INSULIN RECEPTOR SUBSTRATE 1
Authors:Dhe-Paganon, S, Shoelson, S.E.
Deposit date:1999-06-04
Release date:1999-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1.
Proc.Natl.Acad.Sci.USA, 96, 1999

217705

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