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1IRS
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1irs
IRS-1 PTB DOMAIN COMPLEXED WITH A IL-4 RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:IRS-1, IL-4 RECEPTOR PHOSPHOPEPTIDE
Authors:Zhou, M.-M., Huang, B., Olejniczak, E.T., Meadows, R.P., Shuker, S.B., Miyazaki, M., Trub, T., Shoelson, S.E., Feisk, S.W.
Deposit date:1996-03-22
Release date:1997-05-15
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain.
Nat.Struct.Biol., 3, 1996
1J0W
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1j0w
CRYSTAL STRUCTURE ANALYSIS OF THE DOK-5 PTB DOMAIN
Descriptor:downstream of tyrosine kinase 5 (E.C.2.7.1.112)
Authors:Shi, N., Ding, Y., Qiang, B.Q., Yuan, J.G., Rao, Z.H.
Deposit date:2002-11-25
Release date:2003-12-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure Analysis of the Dok-5 PTB Domain
To be Published
1P5T
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1p5t
CRYSTAL STRUCTURE OF DOK1 PTB DOMAIN
Descriptor:Docking protein 1
Authors:Shi, N., Ye, S., Liu, Y., Zhou, W., Ding, Y., Lou, Z., Qiang, B., Yuan, J., Rao, Z.
Deposit date:2003-04-28
Release date:2004-02-17
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain
J.BIOL.CHEM., 279, 2004
1UEF
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1uef
CRYSTAL STRUCTURE OF DOK1 PTB DOMAIN COMPLEX
Descriptor:Docking protein 1/Proto-oncogene tyrosine-protein kinase receptor ret (E.C.2.7.1.112)
Authors:Shi, N., Ye, S., Liu, Y., Zhou, W., Ding, Y., Lou, Z., Qiang, B., Yan, J., Rao, Z.
Deposit date:2003-05-14
Release date:2004-05-25
Modification date:2009-09-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain
J.Biol.Chem., 279, 2004
1XR0
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1xr0
STRUCTURAL BASIS OF SNT PTB DOMAIN INTERACTIONS WITH DISTINCT NEUROTROPHIC RECEPTORS
Descriptor:Basic fibroblast growth factor receptor 1, FGFR signalling adaptor SNT-1
Authors:Dhalluin, C., Yan, K.S., Plotnikova, O., Lee, K.W., Zeng, L., Kuti, M., Mujtaba, S., Goldfarb, M.P., Zhou, M.-M.
Deposit date:2004-10-13
Release date:2004-11-02
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors
Mol.Cell, 6, 2000
2DLW
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2dlw
SOLUTION STRUCTURE OF THE IRS DOMAIN OF HUMAN DOCKING PROTEIN 2, ISOFORM A
Descriptor:Docking protein 2, isoform a
Authors:Zhang, H.P., Kurosaki, C., Yoshida, M., Hayashi, F., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-20
Release date:2006-10-20
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the IRS domain of human docking protein 2, isoform a
to be published
2G35
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2g35
NMR STRUCTURE OF TALIN-PTB IN COMPLEX WITH PIPKI
Descriptor:Talin-1
Authors:Kong, X., Wang, X., Misra, S., Qin, J.
Deposit date:2006-02-17
Release date:2006-05-02
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structural Basis for the Phosphorylation-regulated Focal Adhesion Targeting of Type Igamma Phosphatidylinositol Phosphate Kinase (PIPKIgamma) by Talin.
J.Mol.Biol., 359, 2006
2K00
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2k00
SOLUTION STRUCTURE OF THE TALIN F3 IN COMPLEX WITH LAYILIN CYTODOMAIN
Descriptor:Talin-1, Layilin
Authors:Wegener, K.L., Barsukov, I.L.
Deposit date:2008-01-23
Release date:2008-09-09
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structural basis for the interaction between the cytoplasmic domain of the hyaluronate receptor layilin and the talin F3 subdomain
J.Mol.Biol., 382, 2008
2KGX
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2kgx
HADDOCK STRUCTURE OF THE TALIN F3 DOMAIN IN COMPLEX WITH TALIN 1655-1822
Descriptor:Talin-1, MKIAA1027 protein
Authors:Goult, B.T., Gingras, A.R., Bate, N., Critchley, D.R., Barsukov, I.L.
Deposit date:2009-03-23
Release date:2009-03-31
Modification date:2009-07-07
Method:SOLUTION NMR
Cite:The structure of an interdomain complex that regulates talin activity.
J.Biol.Chem., 284, 2009
2KUP
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2kup
SOLUTION STRUCTURE OF THE COMPLEX OF THE PTB DOMAIN OF SNT-2 AND 19-RESIDUE PEPTIDE (AA 1571-1589) OF HALK
Descriptor:Fibroblast growth factor receptor substrate 3, 19-residue peptide from ALK tyrosine kinase receptor
Authors:Li, H., Koshiba, S., Inoue, M., Kigawa, T., Yokoyama, S.
Deposit date:2010-02-24
Release date:2010-05-26
Modification date:2014-02-12
Method:SOLUTION NMR
Cite:Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
J.Struct.Funct.Genom., 11, 2010
2KUQ
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2kuq
SOLUTION STRUCTURE OF THE CHIMERA OF THE PTB DOMAIN OF SNT-2 AND 19-RESIDUE PEPTIDE (AA 1571-1589) OF HALK
Descriptor:Fibroblast growth factor receptor substrate 3, LINKER, 19-residue peptide from ALK tyrosine kinase receptor
Authors:Li, H., Koshiba, S., Tomizawa, T., Watanabe, S., Harada, T., Kigawa, T., Yokoyama, S.
Deposit date:2010-02-24
Release date:2010-05-26
Modification date:2014-02-12
Method:SOLUTION NMR
Cite:Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
J.Struct.Funct.Genom., 11, 2010
2MFQ
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2mfq
NMR SOLUTION STRUCTURES OF FRS2A PTB DOMAIN WITH NEUROTROPHIN RECEPTOR TRKB
Descriptor:Fibroblast growth factor receptor substrate 2, BDNF/NT-3 growth factors receptor (E.C.2.7.10.1)
Authors:Zeng, L., Zhou, M.
Deposit date:2013-10-18
Release date:2014-03-05
Modification date:2014-06-25
Method:SOLUTION NMR
Cite:Structural insights into FRS2 alpha PTB domain recognition by neurotrophin receptor TrkB.
Proteins, 82, 2014
2V76
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2v76
CRYSTAL STRUCTURE OF THE HUMAN DOK1 PTB DOMAIN
Descriptor:DOCKING PROTEIN 1
Authors:Oxley, C.L., Anthis, N.J., Lowe, E.D., Campbell, I.D., Wegener, K.L.
Deposit date:2007-07-26
Release date:2008-01-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:An Integrin Phosphorylation Switch: The Effect of {Beta}3 Integrin Tail Phosphorylation on Dok1 and Talin Binding.
J.Biol.Chem., 283, 2008
2YS5
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2ys5
SOLUTION STRUCTURE OF THE COMPLEX OF THE PTB DOMAIN OF SNT-2 AND 19-RESIDUE PEPTIDE (AA 1571-1589) OF HALK
Descriptor:Fibroblast growth factor receptor substrate 3, ALK tyrosine kinase receptor (E.C.2.7.10.1)
Authors:Li, H., Koshiba, S., Inoue, M., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-03
Release date:2008-04-08
Modification date:2014-02-12
Method:SOLUTION NMR
Cite:Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
J.Struct.Funct.Genom., 11, 2010
2YT2
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2yt2
SOLUTION STRUCTURE OF THE CHIMERA OF THE PTB DOMAIN OF SNT-2 AND 19-RESIDUE PEPTIDE (AA 1571-1589) OF HALK
Descriptor:Fibroblast growth factor receptor substrate 3 and ALK tyrosine kinase receptor
Authors:Li, H., Koshiba, S., Tomizawa, T., Watanabe, S., Harada, T., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2008-04-08
Modification date:2014-02-12
Method:SOLUTION NMR
Cite:Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
J.Struct.Funct.Genom., 11, 2010
3ML4
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3ml4
CRYSTAL STRUCTURE OF A COMPLEX BETWEEN DOK7 PH-PTB AND THE MUSK JUXTAMEMBRANE REGION
Descriptor:Protein Dok-7, Muscle, skeletal receptor tyrosine-protein kinase
Authors:Bergamin, E., Hubbard, S.R.
Deposit date:2010-04-16
Release date:2010-07-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Cytoplasmic Adaptor Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization.
Mol.Cell, 39, 2010
2H7D
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2h7d
SOLUTION STRUCTURE OF THE TALIN F3 DOMAIN IN COMPLEX WITH A CHIMERIC BETA3 INTEGRIN-PIP KINASE PEPTIDE
Descriptor:Talin-1, Chimera of 24-mer peptide from Integrin beta-3 and 10-mer peptide from Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
Authors:Wegener, K.L.
Deposit date:2006-06-02
Release date:2007-01-30
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structural basis of integrin activation by talin
CELL(CAMBRIDGE,MASS.), 128, 2007
2H7E
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2h7e
SOLUTION STRUCTURE OF THE TALIN F3 DOMAIN IN COMPLEX WITH A CHIMERIC BETA3 INTEGRIN-PIP KINASE PEPTIDE- MINIMIZED AVERAGE STRUCTURE
Descriptor:Talin-1, Chimera of 24-mer peptide from Integrin beta-3 and 10-mer peptide from Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
Authors:Wegener, K.L.
Deposit date:2006-06-02
Release date:2007-01-30
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structural basis of integrin activation by talin
CELL(CAMBRIDGE,MASS.), 128, 2007
1MIX
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1mix
CRYSTAL STRUCTURE OF A FERM DOMAIN OF TALIN
Descriptor:Talin
Authors:Garcia-Alvarez, B., de Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MIZ
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1miz
CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor:integrin beta3/Talin
Authors:Garcia-Alvarez, B., de Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MK7
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1mk7
CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor:Integrin Beta3/Talin
Authors:Garcia-Alvarez, B., De Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1MK9
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1mk9
CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor:Integrin Beta3/talin
Authors:Garcia-Alvarez, B., De Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1QQG
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1qqg
CRYSTAL STRUCTURE OF THE PH-PTB TARGETING REGION OF IRS-1
Descriptor:INSULIN RECEPTOR SUBSTRATE 1
Authors:Dhe-Paganon, S., Shoelson, S.E.
Deposit date:1999-06-04
Release date:1999-08-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1.
Proc.Natl.Acad.Sci.USA, 96, 1999
1Y19
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1y19
STRUCTURAL BASIS FOR PHOSPHATIDYLINOSITOL PHOSPHATE KINASE TYPE I-GAMMA BINDING TO TALIN AT FOCAL ADHESIONS
Descriptor:Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1
Authors:de Pereda, J.M., Wegener, K., Santelli, E., Bate, N., Ginsberg, M.H., Critchley, D.R., Campbell, I.D., Liddington, R.C.
Deposit date:2004-11-17
Release date:2005-01-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
J.Biol.Chem., 280, 2005
3G9W
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3g9w
CRYSTAL STRUCTURE OF TALIN2 F2-F3 IN COMPLEX WITH THE INTEGRIN BETA1D CYTOPLASMIC TAIL
Descriptor:Talin-2, Integrin beta-1D
Authors:Anthis, N.J., Wegener, K.L., Ye, F., Kim, C., Lowe, E.D., Vakonakis, I., Bate, N., Critchley, D.R., Ginsberg, M.H., Campbell, I.D.
Deposit date:2009-02-15
Release date:2009-10-20
Modification date:2014-02-05
Method:X-RAY DIFFRACTION (2.165 Å)
Cite:The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
Embo J., 28, 2009
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104537
entries available on 2014-10-29
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