2QP2
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STRUCTURE OF A MACPF/PERFORIN-LIKE PROTEIN
Descriptor:Unknown protein
Authors:Rosado, C.J., Buckle, A.M., Law, R.H.P., Butcher, R.E., Kan, W.T., Bird, C.H., Ung, K., Browne, K.A., Baran, K., Bashtannyk-Puhalovich, T.A., Faux, N.G., Wong, W., Porter, C.J., Pike, R.N., Ellisdon, A.M., Pearce, M.C., Bottomley, S.P., Emsley, J., Smith, A.I., Rossjohn, J., Hartland, E.L., Voskoboinik, I., Trapani, J.A., Bird, P.I., Dunstone, M.A., Whisstock, J.C.
Deposit date:2007-07-22
Release date:2007-09-04
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A common fold mediates vertebrate defense and bacterial attack
Science, 317, 2007
2QQH
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STRUCTURE OF C8A-MACPF REVEALS MECHANISM OF MEMBRANE ATTACK IN COMPLEMENT IMMUNE DEFENSE
Descriptor:Complement component C8 alpha chain
Authors:Hadders, M.A., Gros, P.
Deposit date:2007-07-26
Release date:2007-09-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense.
Science, 317, 2007
3KK7
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CRYSTAL STRUCTURE OF PUTATIVE CELL INVASION PROTEIN WITH MAC/PERFORIN DOMAIN (NP_812351.1) FROM BACTERIODES THETAIOTAOMICRON VPI-5482 AT 2.46 A RESOLUTION
Descriptor:Putative cell invasion protein with MAC/Perforin domain
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2009-11-04
Release date:2009-11-24
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron.
Acta Crystallogr.,Sect.F, 66, 2010
5J67
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STRUCTURE OF ASTROTACTIN-2, A CONSERVED VERTEBRATE-SPECIFIC AND PERFORIN-LIKE MEMBRANE PROTEIN INVOLVED IN NEURONAL DEVELOPMENT
Descriptor:Astrotactin-2
Authors:Ni, T., Harlos, K., Gilbert, R.J.C.
Deposit date:2016-04-04
Release date:2016-05-25
Modification date:2016-06-15
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.
Open Biology, 6, 2016
5J68
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STRUCTURE OF ASTROTACTIN-2, A CONSERVED VERTEBRATE-SPECIFIC AND PERFORIN-LIKE MEMBRANE PROTEIN INVOLVED IN NEURONAL DEVELOPMENT
Descriptor:Astrotactin-2
Authors:Ni, T., Harlos, K., Gilbert, R.J.C.
Deposit date:2016-04-04
Release date:2016-05-25
Modification date:2016-06-15
Method:X-RAY DIFFRACTION (5.221 Å)
Cite:Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.
Open Biology, 6, 2016
5J69
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STRUCTURE OF ASTROTACTIN-2, A CONSERVED VERTEBRATE-SPECIFIC AND PERFORIN-LIKE MEMBRANE PROTEIN INVOLVED IN NEURONAL DEVELOPMENT
Descriptor:Astrotactin-2
Authors:Ni, T., Harlos, K., Gilbert, R.J.C.
Deposit date:2016-04-04
Release date:2016-05-25
Modification date:2016-06-15
Method:X-RAY DIFFRACTION (3.63 Å)
Cite:Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.
Open Biology, 6, 2016
2RD7
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HUMAN COMPLEMENT MEMBRANE ATTACK PROTEINS SHARE A COMMON FOLD WITH BACTERIAL CYTOLYSINS
Descriptor:Complement component C8 alpha chain, Complement component 8, gamma polypeptide
Authors:Slade, D.J., Lovelace, L.L., Chruszcz, M., Minor, W., Lebioda, L., Sodetz, J.M.
Deposit date:2007-09-21
Release date:2008-05-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of the MACPF Domain of Human Complement Protein C8alpha in Complex with the C8gama Subunit
J.Mol.Biol., 379, 2008
5FMW
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THE POLY-C9 COMPONENT OF THE COMPLEMENT MEMBRANE ATTACK COMPLEX
Descriptor:POLYC9
Authors:Dudkina, N.V., Spicer, B.A., Reboul, C.F., Conroy, P.J., Lukoyanova, N., Elmlund, H., Law, R.H.P., Ekkel, S.M., Kondos, S.C., Goode, R.J.A., Ramm, G., Whisstock, J.C., Saibil, H.R., Dunstone, M.A.
Deposit date:2015-11-10
Release date:2016-02-17
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Structure of the Poly-C9 Component of the Complement Membrane Attack Complex
Nat.Commun., 7, 2016
3OJY
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT COMPONENT C8
Descriptor:Complement component C8 alpha chain, Complement component C8 beta chain, Complement component C8 gamma chain
Authors:Lovelace, L.L., Cooper, C.L., Sodetz, J.M., Lebioda, L.
Deposit date:2010-08-23
Release date:2011-04-13
Modification date:2014-04-16
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
J.Biol.Chem., 286, 2011
3NSJ
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THE X-RAY CRYSTAL STRUCTURE OF LYMPHOCYTE PERFORIN
Descriptor:Perforin-1
Authors:Law, R.H., Whisstock, J.C., Caradoc-Davies, T.T.
Deposit date:2010-07-01
Release date:2010-11-03
Modification date:2010-12-15
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The structural basis for membrane binding and pore formation by lymphocyte perforin.
Nature, 468, 2010
3T5O
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT COMPONENT C6
Descriptor:Complement component C6
Authors:Aleshin, A.E., Stec, B., Bankston, L.A., DiScipio, R.G., Liddington, R.C.
Deposit date:2011-07-27
Release date:2012-02-01
Modification date:2012-04-11
Method:X-RAY DIFFRACTION (2.869 Å)
Cite:Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC).
J.Biol.Chem., 287, 2012
4A5W
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CRYSTAL STRUCTURE OF C5B6
Descriptor:COMPLEMENT C5, COMPLEMENT COMPONENT C6
Authors:Hadders, M.A., Bubeck, D., Forneris, F., Pangburn, M., Llorca, O., Lea, S.M., Gros, P.
Deposit date:2011-10-28
Release date:2012-03-14
Modification date:2012-10-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
Cell Rep., 1, 2012
4E0S
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CRYSTAL STRUCTURE OF C5B-6
Descriptor:Complement C5, Complement component C6
Authors:Aleshin, A.E., Stec, B., DiScipio, R., Liddington, R.C.
Deposit date:2012-03-05
Release date:2012-04-18
Modification date:2012-06-20
Method:X-RAY DIFFRACTION (4.21 Å)
Cite:Crystal structure of c5b-6 suggests structural basis for priming assembly of the membrane attack complex.
J.Biol.Chem., 287, 2012
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