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1DL2
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CRYSTAL STRUCTURE OF CLASS I ALPHA-1,2-MANNOSIDASE FROM SACCHAROMYCES CEREVISIAE AT 1.54 ANGSTROM RESOLUTION
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CLASS I ALPHA-1,2-MANNOSIDASE, ...
Authors:Vallee, F, Lipari, F, Yip, P, Herscovics, A, Howell, P.L.
Deposit date:1999-12-08
Release date:2000-02-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Crystal structure of a class I alpha1,2-mannosidase involved in N-glycan processing and endoplasmic reticulum quality control.
EMBO J., 19, 2000
1FMI
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CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE
Descriptor: CALCIUM ION, ENDOPLASMIC RETICULUM ALPHA-MANNOSIDASE I, SULFATE ION
Authors:Vallee, F, Karaveg, K, Herscovics, A, Moremen, K.W, Howell, P.L.
Deposit date:2000-08-17
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.
J.Biol.Chem., 275, 2000
1FO3
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CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH KIFUNENSINE
Descriptor: ALPHA1,2-MANNOSIDASE, CALCIUM ION, KIFUNENSINE, ...
Authors:Vallee, F, Karaveg, K, Moremen, K.W, Herscovics, A, Howell, P.L.
Deposit date:2000-08-24
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.
J.Biol.Chem., 275, 2000
1FO2
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CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH 1-DEOXYMANNOJIRIMYCIN
Descriptor: 1-DEOXYMANNOJIRIMYCIN, ALPHA1,2-MANNOSIDASE, CALCIUM ION, ...
Authors:Vallee, F, Karaveg, K, Moremen, K.W, Herscovics, A, Howell, P.L.
Deposit date:2000-08-24
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.
J.Biol.Chem., 275, 2000
1G6I
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Crystal structure of the yeast alpha-1,2-mannosidase with bound 1-deoxymannojirimycin at 1.59 A resolution
Descriptor: 1-DEOXYMANNOJIRIMYCIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Herscovics, A, Lipari, F, Sleno, B, Romera, P.A, Vallee, F, Yip, P, Howell, P.A.
Deposit date:2000-11-06
Release date:2003-06-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structure and function of Class I a1,2-mannosidases involved in glycoprotein biosynthesis.
CARBOHYDRATE BIOENGINEERING. INTERDISCIPLINARY APPROACHES., 2002
1HCU
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BU of 1hcu by Molmil
alpha-1,2-mannosidase from Trichoderma reesei
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-1,2-MANNOSIDASE, CALCIUM ION
Authors:Van Petegem, F, Contreras, H, Contreras, R, Van Beeumen, J.
Deposit date:2001-05-09
Release date:2001-10-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Trichoderma Reesei Alpha-1,2-Mannosidase: Structural Basis for the Cleavage of Four Consecutive Mannose Residues
J.Mol.Biol., 312, 2001
1KKT
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BU of 1kkt by Molmil
Structure of P. citrinum alpha 1,2-mannosidase reveals the basis for differences in specificity of the ER and Golgi Class I enzymes
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mannosyl-oligosaccharide alpha-1,2-mannosidase, ...
Authors:Lobsanov, Y.D, Vallee, F, Imberty, A, Yoshida, T, Yip, P, Herscovics, A, Howell, P.L.
Deposit date:2001-12-10
Release date:2002-01-23
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Penicillium citrinum alpha 1,2-mannosidase reveals the basis for differences in specificity of the endoplasmic reticulum and Golgi class I enzymes.
J.Biol.Chem., 277, 2002
1KRF
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STRUCTURE OF P. CITRINUM ALPHA 1,2-MANNOSIDASE REVEALS THE BASIS FOR DIFFERENCES IN SPECIFICITY OF THE ER AND GOLGI CLASS I ENZYMES
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, KIFUNENSINE, ...
Authors:Lobsanov, Y.D, Vallee, F, Imberty, A, Yoshida, T, Yip, P, Herscovics, A, Howell, P.L.
Deposit date:2002-01-09
Release date:2002-02-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Penicillium citrinum alpha 1,2-mannosidase reveals the basis for differences in specificity of the endoplasmic reticulum and Golgi class I enzymes.
J.Biol.Chem., 277, 2002
1KRE
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STRUCTURE OF P. CITRINUM ALPHA 1,2-MANNOSIDASE REVEALS THE BASIS FOR DIFFERENCES IN SPECIFICITY OF THE ER AND GOLGI CLASS I ENZYMES
Descriptor: 1-DEOXYMANNOJIRIMYCIN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Lobsanov, Y.D, Vallee, F, Imberty, A, Yoshida, T, Yip, P, Herscovics, A, Howell, P.L.
Deposit date:2002-01-09
Release date:2002-02-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Penicillium citrinum alpha 1,2-mannosidase reveals the basis for differences in specificity of the endoplasmic reticulum and Golgi class I enzymes.
J.Biol.Chem., 277, 2002
1NXC
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BU of 1nxc by Molmil
Structure of mouse Golgi alpha-1,2-mannosidase IA reveals the molecular basis for substrate specificity among Class I enzymes (family 47 glycosidases)
Descriptor: CALCIUM ION, Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Tempel, W, Liu, Z.-J, Karaveg, K, Rose, J, Moremen, K.W, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-02-10
Release date:2004-05-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Structure of mouse Golgi alpha-mannosidase IA reveals the molecular basis for substrate specificity among class 1 (family 47 glycosylhydrolase) alpha1,2-mannosidases
J.Biol.Chem., 279, 2004
1X9D
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BU of 1x9d by Molmil
Crystal Structure Of Human Class I alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue
Descriptor: 1,4-BUTANEDIOL, CALCIUM ION, Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, ...
Authors:Karaveg, K, Tempel, W, Liu, Z.J, Siriwardena, A, Moremen, K.W, Wang, B.C.
Deposit date:2004-08-20
Release date:2005-02-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Mechanism of class 1 (glycosylhydrolase family 47) {alpha}-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control.
J.Biol.Chem., 280, 2005
2RI9
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BU of 2ri9 by Molmil
Penicillium citrinum alpha-1,2-mannosidase in complex with a substrate analog
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Lobsanov, Y.D, Yoshida, T, Desmet, T, Nerinckx, W, Yip, P, Claeyssens, M, Herscovics, A, Howell, P.L.
Deposit date:2007-10-10
Release date:2008-03-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Modulation of activity by Arg407: structure of a fungal alpha-1,2-mannosidase in complex with a substrate analogue.
Acta Crystallogr.,Sect.D, 64, 2008
2RI8
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Penicillium citrinum alpha-1,2-mannosidase complex with glycerol
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
Authors:Lobsanov, Y.D, Yoshida, T, Desmet, T, Nerinckx, W, Yip, P, Claeyssens, M, Herscovics, A, Howell, P.L.
Deposit date:2007-10-10
Release date:2008-03-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Modulation of activity by Arg407: structure of a fungal alpha-1,2-mannosidase in complex with a substrate analogue.
Acta Crystallogr.,Sect.D, 64, 2008
4AYP
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BU of 4ayp by Molmil
Structure of The GH47 processing alpha-1,2-mannosidase from Caulobacter strain K31 in complex with thiomannobioside
Descriptor: CALCIUM ION, MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE, SODIUM ION, ...
Authors:Thompson, A.J, Dabin, J, Iglesias-Fernandez, J, Iglesias-Fernandez, A, Dinev, Z, Williams, S.J, Siriwardena, A, Moreland, C, Hu, T.C, Smith, D.K, Gilbert, H.J, Rovira, C, Davies, G.J.
Deposit date:2012-06-21
Release date:2013-01-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:The Reaction Coordinate of a Bacterial Gh47 Alpha-Mannosidase: A Combined Quantum Mechanical and Structural Approach.
Angew.Chem.Int.Ed.Engl., 51, 2012
4AYQ
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BU of 4ayq by Molmil
Structure of The GH47 processing alpha-1,2-mannosidase from Caulobacter strain K31 in complex with mannoimidazole
Descriptor: (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Thompson, A.J, Dabin, J, Iglesias-Fernandez, J, Iglesias-Fernandez, A, Dinev, Z, Williams, S.J, Siriwardena, A, Moreland, C, Hu, T.C, Smith, D.K, Gilbert, H.J, Rovira, C, Davies, G.J.
Deposit date:2012-06-21
Release date:2013-01-30
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Reaction Coordinate of a Bacterial Gh47 Alpha-Mannosidase: A Combined Quantum Mechanical and Structural Approach.
Angew.Chem.Int.Ed.Engl., 51, 2012
4AYO
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BU of 4ayo by Molmil
Structure of The GH47 processing alpha-1,2-mannosidase from Caulobacter strain K31
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE, ...
Authors:Thompson, A.J, Dabin, J, Iglesias-Fernandez, J, Iglesias-Fernandez, A, Dinev, Z, Williams, S.J, Siriwardena, A, Moreland, C, Hu, T.C, Smith, D.K, Gilbert, H.J, Rovira, C, Davies, G.J.
Deposit date:2012-06-21
Release date:2013-01-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:The Reaction Coordinate of a Bacterial Gh47 Alpha-Mannosidase: A Combined Quantum Mechanical and Structural Approach.
Angew.Chem.Int.Ed.Engl., 51, 2012
4AYR
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Structure of The GH47 processing alpha-1,2-mannosidase from Caulobacter strain K31 in complex with noeuromycin
Descriptor: (3S,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-2-ONE, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CALCIUM ION, ...
Authors:Thompson, A.J, Dabin, J, Iglesias-Fernandez, J, Iglesias-Fernandez, A, Dinev, Z, Williams, S.J, Siriwardena, A, Moreland, C, Hu, T.C, Smith, D.K, Gilbert, H.J, Rovira, C, Davies, G.J.
Deposit date:2012-06-21
Release date:2013-01-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Reaction Coordinate of a Bacterial Gh47 Alpha-Mannosidase: A Combined Quantum Mechanical and Structural Approach.
Angew.Chem.Int.Ed.Engl., 51, 2012
5KIJ
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BU of 5kij by Molmil
Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase and Man9GlcNAc2-PA complex
Descriptor: 1,4-BUTANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, ...
Authors:Karaveg, K, Xiang, Y, Moremen, K.W.
Deposit date:2016-06-16
Release date:2017-05-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5KKB
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BU of 5kkb by Molmil
Structure of mouse Golgi alpha-1,2-mannosidase IA and Man9GlcNAc2-PA complex
Descriptor: 1,4-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ...
Authors:Xiang, Y, Moremen, K.W.
Deposit date:2016-06-21
Release date:2016-12-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.774 Å)
Cite:Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5KK7
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Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase T688A mutant and Thio-disaccharide substrate analog complex
Descriptor: 1,4-BUTANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ACETATE ION, ...
Authors:Karaveg, K, Xiang, Y, Moremen, K.W.
Deposit date:2016-06-21
Release date:2017-05-10
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.7324 Å)
Cite:Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5MEH
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BU of 5meh by Molmil
Crystal structure of alpha-1,2-mannosidase from Caulobacter K31 strain in complex with 1-deoxymannojirimycin
Descriptor: 1-DEOXYMANNOJIRIMYCIN, ACETATE ION, CALCIUM ION, ...
Authors:Males, A, Davies, G.J.
Deposit date:2016-11-14
Release date:2016-12-21
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Conformational Behaviour of Azasugars Based on Mannuronic Acid.
Chembiochem, 18, 2017
5NE5
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BU of 5ne5 by Molmil
Crystal structure of family 47 alpha-1,2-mannosidase from Caulobacter K31 strain in complex with kifunensine
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, KIFUNENSINE, ...
Authors:Males, A, Davies, G.J.
Deposit date:2017-03-09
Release date:2017-03-29
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Conformational Analysis of the Mannosidase Inhibitor Kifunensine: A Quantum Mechanical and Structural Approach.
Chembiochem, 18, 2017
8B5M
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Crystal structure of GH47 alpha-1,2-mannosidase from Caulobacter K31 strain in complex with cyclosulfamidate inhibitor
Descriptor: (3aR,4S,5S,6R,7R,7aS)-7-(hydroxymethyl)-2,2-bis(oxidanylidene)-3a,4,5,6,7,7a-hexahydro-3H-benzo[d][1,2,3]oxathiazole-4,5,6-triol, CALCIUM ION, Mannosyl-oligosaccharide 1,2-alpha-mannosidase, ...
Authors:Males, A, Davies, G.J.
Deposit date:2022-09-23
Release date:2023-10-04
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:GH47 and Cyclosulfamidate
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