1CHP
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SURPRISING LEADS FOR A CHOLERA TOXIN RECEPTOR BINDING ANTAGONIST; CRYSTALLOGRAPHIC STUDIES OF CTB MUTANTS
Descriptor:CHOLERA TOXIN B PENTAMER
Authors:Merritt, E.A., Hol, W.G.J.
Deposit date:1995-02-15
Release date:1996-03-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Surprising leads for a cholera toxin receptor-binding antagonist: crystallographic studies of CTB mutants.
Structure, 3, 1995
1CT1
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CHOLERA TOXIN B-PENTAMER MUTANT G33R BOUND TO RECEPTOR PENTASACCHARIDE
Descriptor:CHOLERA TOXIN
Authors:Merritt, E.A., Hol, W.G.J.
Deposit date:1997-06-03
Release date:1997-10-15
Modification date:2009-08-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural studies of receptor binding by cholera toxin mutants.
Protein Sci., 6, 1997
1FGB
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TOXIN
Descriptor:CHOLERA TOXIN B SUBUNIT PENTAMER
Authors:Zhang, R.-G., Westbrook, E.
Deposit date:1996-02-21
Release date:1996-12-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The 2.4 A crystal structure of cholera toxin B subunit pentamer: choleragenoid.
J.Mol.Biol., 251, 1995
1G8Z
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HIS57ALA MUTANT OF CHOLERA TOXIN B-PENATMER
Descriptor:CHOLERA TOXIN B PROTEIN
Authors:Aman, A.T., Fraser, S., Merritt, E.A., Rodigherio, C., Kenny, M.
Deposit date:2000-11-21
Release date:2001-07-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:A mutant cholera toxin B subunit that binds GM1- ganglioside but lacks immunomodulatory or toxic activity.
Proc.Natl.Acad.Sci.USA, 98, 2001
1JR0
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CHOLERA TOXIN B-PENTAMER WITH LIGAND BMSC-0011
Descriptor:cholera toxin B subunit
Authors:Merritt, E.A., Hol, W.G.J.
Deposit date:2001-08-09
Release date:2002-05-08
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Anchor-based design of improved cholera toxin and E. coli heat-labile enterotoxin receptor binding antagonists that display multiple binding modes.
Chem.Biol., 9, 2002
1MD2
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CHOLERA TOXIN B-PENTAMER WITH DECAVALENT LIGAND BMSC-0013
Descriptor:CHOLERA TOXIN B SUBUNIT
Authors:Zhang, Z., Merritt, E.A., Ahn, M., Roach, C., Hol, W.G.J., Fan, E.
Deposit date:2002-08-06
Release date:2002-12-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Solution and crystallographic studies of branched multivalent ligands that inhibit the receptor-binding of cholera toxin.
J.Am.Chem.Soc., 124, 2002
1RCV
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CHOLERA TOXIN B-PENTAMER COMPLEXED WITH BIVALENT NITROPHENOL-GALACTOSIDE LIGAND BV1
Descriptor:cholera toxin B protein (CTB)
Authors:Pickens, J.C., Mitchell, D.D., Liu, J., Tan, X., Zhang, Z., Verlinde, C.L., Hol, W.G., Fan, E.
Deposit date:2003-11-04
Release date:2004-10-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer.
Chem.Biol., 11, 2004
1RD9
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CHOLERA TOXIN B-PENTAMER COMPLEXED WITH BIVALENT NITROPHENOL-GALACTOSIDE LIGAND BV2
Descriptor:cholera toxin B protein (CTB)
Authors:Pickens, J.C., Mitchell, D.D., Liu, J., Tan, X., Zhang, Z., Verlinde, C.L., Hol, W.G., Fan, E.
Deposit date:2003-11-05
Release date:2004-10-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer.
Chem.Biol., 11, 2004
1RDP
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CHOLERA TOXIN B-PENTAMER COMPLEXED WITH BIVALENT NITROPHENOL-GALACTOSIDE LIGAND BV3
Descriptor:cholera toxin B protein (CTB)
Authors:Pickens, J.C., Mitchell, D.D., Liu, J., Tan, X., Zhang, Z., Verlinde, C.L., Hol, W.G., Fan, E.
Deposit date:2003-11-05
Release date:2004-10-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer.
Chem.Biol., 11, 2004
1RF2
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CHOLERA TOXIN B-PENTAMER COMPLEXED WITH BIVALENT NITROPHENOL-GALACTOSIDE LIGAND BV4
Descriptor:cholera toxin B protein (CTB)
Authors:Pickens, J.C., Mitchell, D.D., Liu, J., Tan, X., Zhang, Z., Verlinde, C.L., Hol, W.G., Fan, E.
Deposit date:2003-11-07
Release date:2004-10-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer.
Chem.Biol., 11, 2004
1CHQ
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SURPRISING LEADS FOR A CHOLERA TOXIN RECEPTOR BINDING ANTAGONIST; CRYSTALLOGRAPHIC STUDIES OF CTB MUTANTS
Descriptor:CHOLERA TOXIN B PENTAMER
Authors:Merritt, E.A., Hol, W.G.J.
Deposit date:1995-02-15
Release date:1996-03-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Surprising leads for a cholera toxin receptor-binding antagonist: crystallographic studies of CTB mutants.
Structure, 3, 1995
2CHB
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CHOLERA TOXIN B-PENTAMER COMPLEXED WITH GM1 PENTASACCHARIDE
Descriptor:CHOLERA TOXIN
Authors:Merritt, E.A., Hol, W.G.J.
Deposit date:1997-06-03
Release date:1997-12-03
Modification date:2009-07-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural studies of receptor binding by cholera toxin mutants.
Protein Sci., 6, 1997
3CHB
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CHOLERA TOXIN B-PENTAMER COMPLEXED WITH GM1 PENTASACCHARIDE
Descriptor:CHOLERA TOXIN, UNKNOWN ATOM OR ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Merritt, E.A., Hol, W.G.J.
Deposit date:1998-03-24
Release date:1998-08-12
Modification date:2009-07-28
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The 1.25 A resolution refinement of the cholera toxin B-pentamer: evidence of peptide backbone strain at the receptor-binding site.
J.Mol.Biol., 282, 1998
3EFX
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NOVEL BINDING SITE IDENTIFIED IN A HYBRID BETWEEN CHOLERA TOXIN AND HEAT-LABILE ENTEROTOXIN, 1.9A CRYSTAL STRUCTURE REVEALS THE DETAILS
Descriptor:Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
Authors:Holmner, A., Lebens, M., Teneberg, S., Angstrom, J., Okvist, M., Krengel, U.
Deposit date:2008-09-10
Release date:2008-09-23
Modification date:2015-09-02
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin: 1.9 A crystal structure reveals the details
Structure, 12, 2004
5ELC
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CHOLERA TOXIN EL TOR B-PENTAMER IN COMPLEX WITH LEWIS-Y
Descriptor:Cholera enterotoxin subunit B
Authors:Heggelund, J.E., Burschowsky, D., Krengel, U.
Deposit date:2015-11-04
Release date:2016-03-30
Modification date:2016-04-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence.
Plos Pathog., 12, 2016
5ELE
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CHOLERA TOXIN EL TOR B-PENTAMER IN COMPLEX WITH A LEWIS-Y
Descriptor:Cholera enterotoxin subunit B
Authors:Heggelund, J.E., Burschowsky, D., Krengel, U.
Deposit date:2015-11-04
Release date:2016-03-30
Modification date:2016-04-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence.
Plos Pathog., 12, 2016
5ELF
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CHOLERA TOXIN EL TOR B-PENTAMER IN COMPLEX WITH A-PENTASACCHARIDE
Descriptor:Cholera enterotoxin subunit B
Authors:Heggelund, J.E., Burschowsky, D., Krengel, U.
Deposit date:2015-11-04
Release date:2016-03-30
Modification date:2016-04-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence.
Plos Pathog., 12, 2016
1S5B
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CHOLERA HOLOTOXIN WITH AN A-SUBUNIT Y30S MUTATION FORM 3
Descriptor:Cholera enterotoxin, A chain precursor (E.C.2.4.2.36), cholera toxin B protein (CTB)
Authors:O'Neal, C.J., Amaya, E.I., Jobling, M.G., Holmes, R.K., Hol, W.G.
Deposit date:2004-01-20
Release date:2004-04-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism
Biochemistry, 43, 2004
1S5C
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CHOLERA HOLOTOXIN WITH AN A-SUBUNIT Y30S MUTATION, CRYSTAL FORM 1
Descriptor:Cholera enterotoxin, A chain (E.C.2.4.2.36), cholera enterotoxin B-subunit
Authors:O'Neal, C.J., Amaya, E.I., Jobling, M.G., Holmes, R.K., Hol, W.G.
Deposit date:2004-01-20
Release date:2004-04-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism
Biochemistry, 43, 2004
1S5D
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CHOLERA HOLOTOXIN WITH AN A-SUBUNIT Y30S MUTATION, CRYSTAL FORM 2
Descriptor:Cholera enterotoxin, A chain precursor (E.C.2.4.2.36), cholera toxin B protein (CTB)
Authors:O'Neal, C.J., Amaya, E.I., Jobling, M.G., Holmes, R.K., Hol, W.G.
Deposit date:2004-01-20
Release date:2004-04-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism
Biochemistry, 43, 2004
1S5E
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CHOLERA HOLOTOXIN, CRYSTAL FORM 1
Descriptor:Cholera enterotoxin, A chain precursor (E.C.2.4.2.36), cholera toxin B protein (CTB)
Authors:O'Neal, C.J., Amaya, E.I., Jobling, M.G., Holmes, R.K., Hol, W.G.
Deposit date:2004-01-20
Release date:2004-04-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism
Biochemistry, 43, 2004
1S5F
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CHOLERA HOLOTOXIN, CRYSTAL FORM 2
Descriptor:Cholera enterotoxin, A chain (E.C.2.4.2.36), cholera toxin B protein (CTB)
Authors:O'Neal, C.J., Amaya, E.I., Jobling, M.G., Holmes, R.K., Hol, W.G.
Deposit date:2004-01-20
Release date:2004-04-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism
Biochemistry, 43, 2004
1XTC
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CHOLERA TOXIN
Descriptor:CHOLERA TOXIN
Authors:Zhang, R.-G., Westbrook, E.
Deposit date:1996-01-10
Release date:1996-08-01
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The three-dimensional crystal structure of cholera toxin.
J.Mol.Biol., 251, 1995
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