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1CBK
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1cbk
7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN-PYROPHOSPHOKINASE FROM HAEMOPHILUS INFLUENZAE
Descriptor:PYROPHOSPHOKINASE
Authors:Hennig, M., D'Arcy, A., Dale, G., Oefner, C.
Deposit date:1999-02-26
Release date:2000-03-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The structure and function of the 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Haemophilus influenzae.
J.Mol.Biol., 287, 1999
1DY3
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1dy3
TERNARY COMPLEX OF 7,8-DIHYDRO-6-HYDROXYMETHYLPTERINPYROPHOSPHOKINASE FROM ESCHERICHIA COLI WITH ATP AND A SUBSTRATE ANALOGUE.
Descriptor:PROTEIN
Authors:Stammers, D.K., Achari, A., Somers, D.O., Bryant, P.K., Rosemond, J., Scott, D.L., Champness, J.N.
Deposit date:2000-01-21
Release date:2000-08-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:2.0A X-Ray Structure of the Ternary Complex of 7,8-Dihydro-6-Hydroxymethylpterinpyrophosphokinase from Escherichia Coli with ATP and a Substrate Analogue
FEBS Lett., 456, 1999
1EQ0
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1eq0
SOLUTION STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE COMPLEXED WITH MGAMPPCP
Descriptor:6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE COMPLEXED WITH MGAMPPCP
Authors:Shi, G., Yan, H.
Deposit date:2000-03-30
Release date:2001-11-07
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Unusual conformational changes in 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as revealed by X-ray crystallography and NMR.
J.Biol.Chem., 276, 2001
1EQM
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1eqm
CRYSTAL STRUCTURE OF BINARY COMPLEX OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE WITH ADENOSINE-5'-DIPHOSPHATE
Descriptor:6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE (E.C. 2.7.6.3)
Authors:Xiao, B., Blaszczyk, J., Ji, X.
Deposit date:2000-04-05
Release date:2001-04-05
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unusual conformational changes in 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as revealed by X-ray crystallography and NMR.
J.Biol.Chem., 276, 2001
1EX8
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1ex8
CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE COMPLEXED WITH HP4A, THE TWO-SUBSTRATE-MIMICKING INHIBITOR
Descriptor:6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE (E.C. 2.7.6.3)
Authors:Blaszczyk, J., Ji, X.
Deposit date:2000-05-01
Release date:2001-05-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: synthesis and biochemical and crystallographic studies.
J.Med.Chem., 44, 2001
1F9H
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1f9h
CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF E. COLI HPPK(R92A) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.50 ANGSTROM RESOLUTION
Descriptor:6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE (E.C. 2.7.6.3)
Authors:Blaszczyk, J., Ji, X.
Deposit date:2000-07-10
Release date:2003-04-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003
1G4C
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1g4c
CRYSTAL STRUCTURE OF A COMPLEX OF HPPK(R92A) FROM E.COLI WITH MG2+ AT 1.65 ANGSTROM RESOLUTION
Descriptor:2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE PYROPHOSPHOKINASE (E.C.2.7.6.3)
Authors:Blaszczyk, J., Ji, X.
Deposit date:2000-10-26
Release date:2003-04-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003
1HKA
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1hka
6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE
Descriptor:6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE
Authors:Xiao, B., Shi, G., Chen, X., Yan, H., Ji, X.
Deposit date:1998-09-29
Release date:1999-06-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, a potential target for the development of novel antimicrobial agents.
Structure Fold.Des., 7, 1999
1HQ2
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1hq2
CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E.COLI HPPK(R82A) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.25 ANGSTROM RESOLUTION
Descriptor:6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE (E.C.2.7.6.3)
Authors:Blaszczyk, J., Ji, X.
Deposit date:2000-12-13
Release date:2003-04-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003
1IM6
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1im6
CRYSTAL STRUCTURE OF UNLIGATED HPPK(R82A) FROM E.COLI AT 1.74 ANGSTROM RESOLUTION
Descriptor:6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE (E.C.2.7.6.3)
Authors:Blaszczyk, J., Ji, X.
Deposit date:2001-05-09
Release date:2003-04-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003
1KBR
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1kbr
CRYSTAL STRUCTURE OF UNLIGATED HPPK(R92A) FROM E.COLI AT 1.55 ANGSTROM RESOLUTION
Descriptor:6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE (E.C.2.7.6.3)
Authors:Blaszczyk, J., Ji, X.
Deposit date:2001-11-06
Release date:2003-04-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003
1Q0N
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1q0n
CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE FROM E. COLI WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.25 ANGSTROM RESOLUTION
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (E.C.2.7.6.3)
Authors:Blaszczyk, J., Ji, X.
Deposit date:2003-07-16
Release date:2003-08-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Catalytic Center Assembly of Hppk as Revealed by the Crystal Structure of a Ternary Complex at 1.25 A Resolution
Structure, 8, 2000
1RAO
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1rao
CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E. COLI HPPK WITH AMP AND 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE AT 1.56 ANGSTROM RESOLUTION
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (E.C.2.7.6.3)
Authors:Blaszczyk, J., Ji, X.
Deposit date:2003-10-31
Release date:2004-11-09
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Reaction trajectory of pyrophosphoryl transfer catalyzed by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Structure, 12, 2004
1RB0
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1rb0
CRYSTAL STRUCTURE OF A BINARY COMPLEX OF E. COLI HPPK WITH 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE AT 1.35 ANGSTROM RESOLUTION
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (E.C.2.7.6.3)
Authors:Blaszczyk, J., Ji, X.
Deposit date:2003-10-31
Release date:2004-11-09
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Reaction trajectory of pyrophosphoryl transfer catalyzed by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Structure, 12, 2004
1RTZ
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1rtz
CRYSTAL STRUCTURE OF E.COLI APO-HPPK(V83G/DEL84-89) AT 1.33 ANGSTROM RESOLUTION
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (E.C.2.7.6.3)
Authors:Blaszczyk, J., Ji, X.
Deposit date:2003-12-10
Release date:2004-02-24
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Essential Roles of a Dynamic Loop in the Catalysis of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase.
Biochemistry, 43, 2004
1RU1
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1ru1
CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E. COLI HPPK(V83G/DEL84-89) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.40 ANGSTROM RESOLUTION (MONOCLINIC FORM)
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (E.C.2.7.6.3)
Authors:Blaszczyk, J., Ji, X.
Deposit date:2003-12-10
Release date:2004-02-24
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Essential Roles of a Dynamic Loop in the Catalysis of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase.
Biochemistry, 43, 2004
1RU2
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1ru2
CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E.COLI HPPK(V83G/DEL84-89) WITH MGAMPCPP AND 6-HYDROXYMETHYLPTERIN AT 1.48 ANGSTROM RESOLUTION (ORTHORHOMBIC FORM)
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (E.C.2.7.6.3)
Authors:Blaszczyk, J., Ji, X.
Deposit date:2003-12-10
Release date:2004-02-24
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Essential Roles of a Dynamic Loop in the Catalysis of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase.
Biochemistry, 43, 2004
1TMJ
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1tmj
CRYSTAL STRUCTURE OF E.COLI APO-HPPK(W89A) AT 1.45 ANGSTROM RESOLUTION
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (E.C.2.7.6.3)
Authors:Blaszczyk, J., Ji, X.
Deposit date:2004-06-10
Release date:2005-06-21
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Is the Critical Role of Loop 3 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase in Catalysis Due to Loop-3 Residues Arginine-84 and Tryptophan-89? Site-Directed Mutagenesis, Biochemical, and Crystallographic Studies.
Biochemistry, 44, 2005
1TMM
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1tmm
CRYSTAL STRUCTURE OF TERNARY COMPLEX OF E.COLI HPPK(W89A) WITH MGAMPCPP AND 6-HYDROXYMETHYLPTERIN
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (E.C.2.7.6.3)
Authors:Blaszczyk, J., Li, Y., Wu, Y., Shi, G., Ji, X., Yan, H.
Deposit date:2004-06-10
Release date:2005-06-21
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Is the Critical Role of Loop 3 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase in Catalysis Due to Loop-3 Residues Arginine-84 and Tryptophan-89? Site-Directed Mutagenesis, Biochemical, and Crystallographic Studies.
Biochemistry, 44, 2005
2F63
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2f63
SOLUTION STRUCTURE OF HPPK IN COMPLEX WITH INHIBITOR ANALOGS AMPCPP AND HP-1
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (E.C.2.7.6.3)
Authors:Yan, H., Li, G.
Deposit date:2005-11-28
Release date:2006-01-17
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of HPPK in complex with inhibitor analogs AMPCPP and HP-1
To be Published
2F65
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2f65
SOLUTION STRUCTURE OF HPPK IN COMPLEX WITH INHIBITOR ANALOG AMPCPP
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (E.C.2.7.6.3)
Authors:Yan, H., Li, G.
Deposit date:2005-11-28
Release date:2006-01-17
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of HPPK in complex with inhibitor analog AMPCPP
to be published
2QX0
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2qx0
CRYSTAL STRUCTURE OF YERSINIA PESTIS HPPK (TERNARY COMPLEX)
Descriptor:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (E.C.2.7.6.3)
Authors:Blaszczyk, J., Cherry, S., Tropea, J.E., Waugh, D.S., Ji, X.
Deposit date:2007-08-10
Release date:2007-10-23
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and activity of Yersinia pestis 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as a novel target for the development of antiplague therapeutics.
Acta Crystallogr.,Sect.D, 63, 2007
3HCX
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3hcx
CRYSTAL STRUCTURE OF E. COLI HPPK(N10A)
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (E.C.2.7.6.3)
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-05-06
Release date:2010-05-19
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Role of loop coupling in enzymatic catalysis and conformational dynamics
To be Published
3HD1
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3hd1
CRYSTAL STRUCTURE OF E. COLI HPPK(N10A) IN COMPLEX WITH MGAMPCPP
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (E.C.2.7.6.3)
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-05-06
Release date:2010-05-19
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Role of loop coupling in enzymatic catalysis and conformational dynamics
To be Published
3HD2
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3hd2
CRYSTAL STRUCTURE OF E. COLI HPPK(Q50A) IN COMPLEX WITH MGAMPCPP AND PTERIN
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (E.C.2.7.6.3)
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-05-06
Release date:2010-05-19
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Role of loop coupling in enzymatic catalysis and conformational dynamics
To be Published
<123>
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entries available on 2014-11-26
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