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2IF1
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BU of 2if1 by Molmil
HUMAN TRANSLATION INITIATION FACTOR EIF1, NMR, 29 STRUCTURES
Descriptor: EIF1
Authors:Fletcher, C.M, Hellen, C.U.T, Pestova, T.V, Wagner, G.
Deposit date:1998-08-04
Release date:1999-05-18
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structure and interactions of the translation initiation factor eIF1.
EMBO J., 18, 1999
1D1R
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BU of 1d1r by Molmil
NMR SOLUTION STRUCTURE OF THE PRODUCT OF THE E. COLI YCIH GENE.
Descriptor: HYPOTHETICAL 11.4 KD PROTEIN YCIH IN PYRF-OSMB INTERGENIC REGION
Authors:Cort, J.R, Koonin, E.V, Bash, P.A, Kennedy, M.A.
Deposit date:1999-09-20
Release date:1999-10-06
Last modified:2022-12-21
Method:SOLUTION NMR
Cite:A phylogenetic approach to target selection for structural genomics: solution structure of YciH.
Nucleic Acids Res., 27, 1999
2OGH
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BU of 2ogh by Molmil
Solution structure of yeast eIF1
Descriptor: Eukaryotic translation initiation factor eIF-1
Authors:Reibarkh, M, del Rio, F, Yamamoto, Y, Asano, K, Wagner, G.
Deposit date:2007-01-05
Release date:2007-11-20
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Eukaryotic Initiation Factor (eIF) 1 Carries Two Distinct eIF5-binding Faces Important for Multifactor Assembly and AUG Selection.
J.Biol.Chem., 283, 2008
4BTS
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BU of 4bts by Molmil
THE CRYSTAL STRUCTURE OF THE EUKARYOTIC 40S RIBOSOMAL SUBUNIT IN COMPLEX WITH EIF1 AND EIF1A
Descriptor: 18S ribosomal RNA, 40S RIBOSOMAL PROTEIN RACK1, 40S RIBOSOMAL PROTEIN RPS10E, ...
Authors:Weisser, M, Voigts-Hoffmann, F, Rabl, J, Leibundgut, M, Ban, N.
Deposit date:2013-06-19
Release date:2013-07-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.703 Å)
Cite:The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A.
Nat. Struct. Mol. Biol., 20, 2013
4KZX
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BU of 4kzx by Molmil
Rabbit 40S ribosomal subunit in complex with eIF1.
Descriptor: 18S ribosomal RNA, 40S Ribosomal protein S9, 40S ribosomal protein RACK1, ...
Authors:Lomakin, I.B, Steitz, T.A.
Deposit date:2013-05-30
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (7.809 Å)
Cite:The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
4KZY
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BU of 4kzy by Molmil
Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A.
Descriptor: 18S Ribosomal RNA, 40S Ribosomal Protein RACK1, 40S Ribosomal Protein S10, ...
Authors:Lomakin, I.B, Steitz, T.A.
Deposit date:2013-05-30
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (7.01 Å)
Cite:The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
4MO0
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BU of 4mo0 by Molmil
Crystal structure of aIF1 from Methanocaldococcus jannaschii
Descriptor: Protein translation factor SUI1 homolog
Authors:Schmitt, E, Mechulam, Y.
Deposit date:2013-09-11
Release date:2014-09-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of aIF1 from Methanocaldococcus jannaschii
To be Published
3J81
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BU of 3j81 by Molmil
CryoEM structure of a partial yeast 48S preinitiation complex
Descriptor: 18S rRNA, MAGNESIUM ION, METHIONINE, ...
Authors:Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V.
Deposit date:2014-08-29
Release date:2014-11-05
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
3J80
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BU of 3j80 by Molmil
CryoEM structure of 40S-eIF1-eIF1A preinitiation complex
Descriptor: 18S rRNA, MAGNESIUM ION, RACK1, ...
Authors:Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V.
Deposit date:2014-08-28
Release date:2014-11-05
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
4UER
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BU of 4uer by Molmil
40S-eIF1-eIF1A-eIF3-eIF3j translation initiation complex from Lachancea kluyveri
Descriptor: 18S RRNA, EIF1, EIF1A, ...
Authors:Aylett, C.H.S, Boehringer, D, Erzberger, J.P, Schaefer, T, Ban, N.
Deposit date:2014-12-18
Release date:2015-02-11
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (6.47 Å)
Cite:Structure of a Yeast 40S-Eif1-Eif1A-Eif3-Eif3J Initiation Complex
Nat.Struct.Mol.Biol., 22, 2015
3JAM
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BU of 3jam by Molmil
CryoEM structure of 40S-eIF1A-eIF1 complex from yeast
Descriptor: 18S rRNA, MAGNESIUM ION, RACK1, ...
Authors:Llacer, J.L, Hussain, T, Ramakrishnan, V.
Deposit date:2015-06-17
Release date:2015-08-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
3JAP
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BU of 3jap by Molmil
Structure of a partial yeast 48S preinitiation complex in closed conformation
Descriptor: 18S rRNA, MAGNESIUM ION, METHIONINE, ...
Authors:Llacer, J.L, Hussain, T, Ramakrishnan, V.
Deposit date:2015-06-18
Release date:2015-08-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
2RVH
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BU of 2rvh by Molmil
NMR structure of eIF1
Descriptor: Eukaryotic translation initiation factor eIF-1
Authors:Nagata, T, Obayashi, E, Asano, K.
Deposit date:2015-10-16
Release date:2016-10-26
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5
Cell Rep, 18, 2017
5JB3
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BU of 5jb3 by Molmil
Cryo-EM structure of a full archaeal ribosomal translation initiation complex in the P-REMOTE conformation
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Coureux, P.-D, Schmitt, E, Mechulam, Y.
Deposit date:2016-04-13
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (5.34 Å)
Cite:Cryo-EM study of start codon selection during archaeal translation initiation.
Nat Commun, 7, 2016
5JBH
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BU of 5jbh by Molmil
Cryo-EM structure of a full archaeal ribosomal translation initiation complex in the P-IN conformation
Descriptor: 16S ribosomal RNA, 30S ribosomal protein SX, 30S ribosomal protein eL41, ...
Authors:Coureux, P.-D, Schmitt, E, Mechulam, Y.
Deposit date:2016-04-13
Release date:2016-12-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (5.34 Å)
Cite:Cryo-EM study of start codon selection during archaeal translation initiation.
Nat Commun, 7, 2016
5VYC
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BU of 5vyc by Molmil
Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1.
Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
Authors:Lomakin, I.B, Stolboushkina, E.A, Vaidya, A.T, Garber, M.B, Dmitriev, S.E, Steitz, T.A.
Deposit date:2017-05-24
Release date:2017-07-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (6 Å)
Cite:Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1.
Cell Rep, 20, 2017
5OA9
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BU of 5oa9 by Molmil
Human translation re-initiation complex containing eIF2D
Descriptor: Eukaryotic translation initiation factor 2D
Authors:Weisser, M, Schaefer, T, Leibundgut, M, Boehringer, D, Aylett, C.H.S, Ban, N.
Deposit date:2017-06-21
Release date:2017-07-26
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Functional Insights into Human Re-initiation Complexes.
Mol. Cell, 67, 2017
5W2F
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BU of 5w2f by Molmil
Crystal Structure of the C-terminal Domain of Human eIF2D at 1.4 A resolution
Descriptor: Eukaryotic translation initiation factor 2D, FORMIC ACID
Authors:Vaidya, A.T, Lomakin, I.B, Joseph, N.N, Dmitriev, S.E, Steitz, T.A.
Deposit date:2017-06-06
Release date:2017-08-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of the C-terminal Domain of Human eIF2D and Its Implications on Eukaryotic Translation Initiation.
J. Mol. Biol., 429, 2017
5OA3
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BU of 5oa3 by Molmil
Human 40S-eIF2D-re-initiation complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Weisser, M, Schaefer, T, Leibundgut, M, Boehringer, D, Aylett, C.H.S, Ban, N.
Deposit date:2017-06-20
Release date:2017-08-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural and Functional Insights into Human Re-initiation Complexes.
Mol. Cell, 67, 2017
5ZCY
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BU of 5zcy by Molmil
Crystal structure of archaeal translation initiation factor 1 at 1.5 Angstroms resolution
Descriptor: NITRATE ION, NITRITE ION, Protein translation factor SUI1 homolog
Authors:Gogoi, P, Kanaujia, S.P.
Deposit date:2018-02-22
Release date:2018-05-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Archaeal and eukaryal translation initiation factor 1 differ in their RNA interacting loops.
FEBS Lett., 592, 2018
6GSN
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BU of 6gsn by Molmil
Structure of a partial yeast 48S preinitiation complex in closed conformation
Descriptor: 18S rRNA (1798-MER), 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-06-26
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (5.75 Å)
Cite:Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Nucleic Acids Res., 2021
6GSM
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BU of 6gsm by Molmil
Structure of a partial yeast 48S preinitiation complex in open conformation.
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-07-31
Last modified:2023-02-22
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Nucleic Acids Res., 2021
6VPR
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BU of 6vpr by Molmil
Crystal structure of the C-terminal domain of DENR
Descriptor: ACETATE ION, Density-regulated protein, L(+)-TARTARIC ACID, ...
Authors:Lomakin, I.B, Steitz, T.A.
Deposit date:2020-02-04
Release date:2020-04-08
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the C-terminal domain of DENR.
Comput Struct Biotechnol J, 18, 2020
6VPQ
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Crystal structure of the C-terminal domain of DENR
Descriptor: ACETATE ION, CALCIUM ION, Density-regulated protein, ...
Authors:Lomakin, I.B, Steitz, T.A.
Deposit date:2020-02-04
Release date:2020-04-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of the C-terminal domain of DENR.
Comput Struct Biotechnol J, 18, 2020
6ZP4
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BU of 6zp4 by Molmil
SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-08
Release date:2020-07-29
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020

 

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