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1CA7
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1ca7
MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) WITH HYDROXPHENYLPYRUVATE
Descriptor:MACROPHAGE MIGRATION INHIBITORY FACTOR
Authors:Lubetsky, J.B., Lolis, E.
Deposit date:1999-02-25
Release date:1999-06-30
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Pro-1 of macrophage migration inhibitory factor functions as a catalytic base in the phenylpyruvate tautomerase activity.
Biochemistry, 38, 1999
1CGQ
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1cgq
MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) WITH ALANINE INSERTED BETWEEN PRO-1 AND MET-2
Descriptor:MACROPHAGE MIGRATION INHIBITORY FACTOR
Authors:Lubetsky, J.B., Lolis, E.
Deposit date:1999-03-25
Release date:1999-06-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Pro-1 of macrophage migration inhibitory factor functions as a catalytic base in the phenylpyruvate tautomerase activity.
Biochemistry, 38, 1999
1DPT
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1dpt
D-DOPACHROME TAUTOMERASE
Descriptor:D-DOPACHROME TAUTOMERASE
Authors:Sugimoto, H., Taniguchi, M., Nakagawa, A., Tanaka, I.
Deposit date:1998-05-11
Release date:1999-03-30
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Crystal structure of human D-dopachrome tautomerase, a homologue of macrophage migration inhibitory factor, at 1.54 A resolution.
Biochemistry, 38, 1999
1FIM
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1fim
MACROPHAGE MIGRATION INHIBITORY FACTOR
Descriptor:MACROPHAGE MIGRATION INHIBITORY FACTOR
Authors:Suzuki, M., Sugimoto, H., Nakagawa, A., Tanaka, I.
Deposit date:1996-01-31
Release date:1996-07-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the macrophage migration inhibitory factor from rat liver.
Nat.Struct.Biol., 3, 1996
1GCZ
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1gcz
MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) COMPLEXED WITH INHIBITOR.
Descriptor:MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) COMPLEXED WITH INHIBITOR.
Authors:Katayama, N., Kurihara, H.
Deposit date:2000-08-24
Release date:2001-02-21
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Coumarin and chromen-4-one analogues as tautomerase inhibitors of macrophage migration inhibitory factor: discovery and X-ray crystallography.
J.Med.Chem., 44, 2001
1GD0
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1gd0
HUMAN MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF)
Descriptor:HUMAN MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF)
Authors:Kurihara, H., Katayama, N.
Deposit date:2000-08-24
Release date:2001-02-21
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Coumarin and chromen-4-one analogues as tautomerase inhibitors of macrophage migration inhibitory factor: discovery and X-ray crystallography.
J.Med.Chem., 44, 2001
1GIF
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1gif
HUMAN GLYCOSYLATION-INHIBITING FACTOR
Descriptor:GLYCOSYLATION-INHIBITING FACTOR
Authors:Kato, Y., Kuroki, R.
Deposit date:1996-02-27
Release date:1997-03-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of human glycosylation-inhibiting factor is a trimeric barrel with three 6-stranded beta-sheets.
Proc.Natl.Acad.Sci.USA, 93, 1996
1HFO
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1hfo
THE STRUCTURE OF THE MACROPHAGE MIGRATION INHIBITORY FACTOR FROM TRICHINELLA SPIRALIS.
Descriptor:MIGRATION INHIBITORY FACTOR
Authors:Roe, S.M., Meyer, D.J.
Deposit date:2000-12-07
Release date:2001-08-30
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Macrophage Migration Inhibitory Factor of the Parasitic Nematode Trichinella Spiralis
Biochem.J., 357, 2001
1LJT
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1ljt
CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR COMPLEXED WITH (S,R)-3-(4-HYDROXYPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE-ACETIC ACID METHYL ESTER (ISO-1)
Descriptor:Macrophage migration inhibitory factor, 3-(4-HYDROXYPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE-ACETIC ACID METHYL ESTER
Authors:Lubetsky, J.B., Dios, A., Han, J., Aljabari, B., Ruzsicska, B., Mitchell, R., Lolis, E., Al-Abed, Y.
Deposit date:2002-04-22
Release date:2002-11-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Tautomerase Active Site of Macrophage Migration Inhibitory factor is a Potential Target for Discovery of Novel Anti-inflammatory Agents
J.Biol.Chem., 277, 2002
1MFF
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1mff
MACROPHAGE MIGRATION INHIBITORY FACTOR Y95F MUTANT
Descriptor:MACROPHAGE MIGRATION INHIBITORY FACTOR
Authors:Taylor, A.B., Stamps, S.L., Wang, S.C., Hackert, M.L., Whitman, C.P.
Deposit date:1998-10-19
Release date:1999-07-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor: properties of the P1G, P1A, Y95F, and N97A mutants.
Biochemistry, 39, 2000
1MFI
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1mfi
CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR COMPLEXED WITH (E)-2-FLUORO-P-HYDROXYCINNAMATE
Descriptor:MACROPHAGE MIGRATION INHIBITORY FACTOR
Authors:Taylor, A.B., Johnson Jr., W.H., Czerwinski, R.M., Whitman, C.P., Hackert, M.L.
Deposit date:1998-08-12
Release date:1999-06-22
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibition.
Biochemistry, 38, 1999
1MIF
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1mif
MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF)
Descriptor:MACROPHAGE MIGRATION INHIBITORY FACTOR
Authors:Sun, H.-W., Lolis, E.
Deposit date:1996-01-26
Release date:1996-12-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure at 2.6-A resolution of human macrophage migration inhibitory factor.
Proc.Natl.Acad.Sci.USA, 93, 1996
1P1G
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1p1g
MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) WITH PRO-1 MUTATED TO GLY-1
Descriptor:MACROPHAGE MIGRATION INHIBITORY FACTOR
Authors:Lubetsky, J.B., Lolis, E.
Deposit date:1999-03-24
Release date:1999-06-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Pro-1 of macrophage migration inhibitory factor functions as a catalytic base in the phenylpyruvate tautomerase activity.
Biochemistry, 38, 1999
1UIZ
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1uiz
CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR FROM XENOPUS LAEVIS.
Descriptor:Macrophage Migration Inhibitory Factor
Authors:Suzuki, M., Takamura, Y., Maeno, M., Tochinai, S., Iyaguchi, D., Tanaka, I., Nishihira, J., Ishibashi, T.
Deposit date:2003-07-24
Release date:2004-05-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Xenopus laevis Macrophage Migration Inhibitory Factor Is Essential for Axis Formation and Neural Development.
J.Biol.Chem., 279, 2004
2GDG
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2gdg
CRYSTAL STRUCTURE OF COVALENTLY MODIFIED MACROPHAGE INHIBITORY FACTOR
Descriptor:Macrophage migration inhibitory factor (E.C.5.3.2.1)
Authors:Golubkov, P.A., Hackert, M.L.
Deposit date:2006-03-16
Release date:2006-07-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Inactivation of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor by 2-oxo-4-phenyl-3-butynoate.
Bioorg.Chem., 34, 2006
2OOH
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2ooh
CRYSTAL STRUCTURE OF MIF BOUND TO A NOVEL INHIBITOR, OXIM-11
Descriptor:Macrophage migration inhibitory factor (E.C.5.3.2.1)
Authors:Crichlow, G.V., Al-Abed, Y., Lolis, E.
Deposit date:2007-01-25
Release date:2007-06-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
J.Biol.Chem., 282, 2007
2OOW
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2oow
MIF BOUND TO A FLUORINATED OXIM DERIVATIVE
Descriptor:Macrophage migration inhibitory factor (E.C.5.3.2.1)
Authors:Crichlow, G.V., Al-Abed, Y., Lolis, E.
Deposit date:2007-01-26
Release date:2007-06-05
Modification date:2012-06-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
J.Biol.Chem., 282, 2007
2OOZ
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2ooz
MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) COMPLEXED WITH OXIM6 (AN OXIM DERIVATIVE NOT CONTAINING A RING IN ITS R-GROUP)
Descriptor:Macrophage migration inhibitory factor (E.C.5.3.2.1)
Authors:Crichlow, G.V., Al-Abed, Y., Lolis, E.
Deposit date:2007-01-26
Release date:2007-06-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
J.Biol.Chem., 282, 2007
2OS5
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2os5
MACROPHAGE MIGRATION INHIBITORY FACTOR FROM ANCYLOSTOMA CEYLANICUM
Descriptor:AceMIF
Authors:Cho, Y., Lolis, E.
Deposit date:2007-02-05
Release date:2007-06-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional characterization of a secreted hookworm Macrophage Migration Inhibitory Factor (MIF) that interacts with the human MIF receptor CD74.
J.Biol.Chem., 282, 2007
2WKB
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2wkb
CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR FROM PLASMODIUM BERGHEI
Descriptor:MACROPHAGE MIGRATION INHIBITORY FACTOR
Authors:Dobson, S.E., Augustijn, K.D., Brannigan, J.A., Dodson, E.J., Waters, A.P., Wilkinson, A.J.
Deposit date:2009-06-08
Release date:2009-10-27
Modification date:2011-06-15
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:The Crystal Structures of Macrophage Migration Inhibition Factor (Mif) from Plasmodium Falciparum and Plasmodium Berghei.
Protein Sci., 18, 2009
2XCZ
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2xcz
CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR HOMOLOGUE FROM PROCHLOROCOCCUS MARINUS
Descriptor:POSSIBLE ATLS1-LIKE LIGHT-INDUCIBLE PROTEIN
Authors:Wasiel, A.A., Rozeboom, H.J., Hauke, D., Baas, B.J., Zandvoort, E., Quax, W.J., Thunnissen, A.M.W.H., Poelarends, G.J.
Deposit date:2010-04-27
Release date:2010-09-01
Modification date:2011-07-06
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structural and Functional Characterization of a Macrophage Migration Inhibitory Factor Homologue from the Marine Cyanobacterium Prochlorococcus Marinus.
Biochemistry, 49, 2010
3B64
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3b64
MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) FROM /LEISHMANIA MAJOR
Descriptor:Macrophage migration inhibitory factor-like protein
Authors:Zierow, S., Cho, Y., Lolis, E.
Deposit date:2007-10-27
Release date:2008-06-10
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:A leishmania ortholog of macrophage migration inhibitory factor modulates host macrophage responses.
J.Immunol., 180, 2008
3B9S
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3b9s
MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) COMPLEXED WITH INHIBITOR, 4-IPP.
Descriptor:Macrophage Migration Inhibitory Factor
Authors:Zierow, S., Crichlow, G., Lolis, E.
Deposit date:2007-11-06
Release date:2008-09-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A novel, macrophage migration inhibitory factor suicide substrate inhibits motility and growth of lung cancer cells.
Cancer Res., 68, 2008
3CE4
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3ce4
STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR COVALENTLY INHIBITED BY PMSF TREATMENT
Descriptor:Macrophage migration inhibitory factor
Authors:Crichlow, G.V., Lolis, E.
Deposit date:2008-02-28
Release date:2008-12-30
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions.
Biochemistry, 48, 2009
3DJH
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3djh
MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) AT 1.25 A RESOLUTION
Descriptor:Macrophage migration inhibitory factor (E.C.5.3.2.1)
Authors:Crichlow, G.V., Lolis, E.
Deposit date:2008-06-23
Release date:2008-12-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions.
Biochemistry, 48, 2009
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