1B57
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CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE IN COMPLEX WITH PHOSPHOGLYCOLOHYDROXAMATE
Descriptor:PROTEIN (FRUCTOSE-BISPHOSPHATE ALDOLASE II) (4.1.2.13)
Authors:Hall, D.R., Hunter, W.N.
Deposit date:1999-01-12
Release date:2000-01-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of Escherichia coli class II fructose-1, 6-bisphosphate aldolase in complex with phosphoglycolohydroxamate reveals details of mechanism and specificity.
J.Mol.Biol., 287, 1999
1DOS
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STRUCTURE OF FRUCTOSE-BISPHOSPHATE ALDOLASE
Descriptor:ALDOLASE CLASS II
Authors:Blom, N., Tetreault, S., Coulombe, R., Sygusch, J.
Deposit date:1996-06-24
Release date:1997-07-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Novel active site in Escherichia coli fructose 1,6-bisphosphate aldolase.
Nat.Struct.Biol., 3, 1996
1GVF
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STRUCTURE OF TAGATOSE-1,6-BISPHOSPHATE ALDOLASE
Descriptor:TAGATOSE-BISPHOSPHATE ALDOLASE AGAY (E.C.4.1.2.40)
Authors:Hall, D.R., Hunter, W.N.
Deposit date:2002-02-11
Release date:2002-06-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of Tagatose-1,6-Bisphosphate Aldolase; Insight Into Chiral Discrimination, Mechanism and Specificity of Class II Aldolases
J.Biol.Chem., 277, 2002
1GYN
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CLASS II FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE WITH CADMIUM (NOT ZINC) IN THE ACTIVE SITE
Descriptor:FRUCTOSE-BISPHOSPHATE ALDOLASE II (E.C.4.1.2.13)
Authors:Hall, D.R., Kemp, L.E., Leonard, G.A., Berry, A., Hunter, W.N.
Deposit date:2002-04-27
Release date:2003-02-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Organization of Divalent Cations in the Active Site of Cadmium Escherichia Coli Fructose 1,6-Bisphosphate Aldolase
Acta Crystallogr.,Sect.D, 59, 2003
1RV8
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CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE FROM THERMUS AQUATICUS IN COMPLEX WITH COBALT
Descriptor:fructose-1,6-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Izard, T., Sygusch, J.
Deposit date:2003-12-12
Release date:2004-01-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Induced Fit Movements and Metal Cofactor Selectivity of Class II Aldolases: STRUCTURE OF THERMUS AQUATICUS FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE.
J.Biol.Chem., 279, 2004
1RVG
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CRYSTAL STRCUTURE OF CLASS II FRUCTOSE-BISPHOSPHATE ALDOLASE FROM THERMUS AQUATICUS IN COMPLEX WITH Y
Descriptor:fructose-1,6-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Izard, T., Sygusch, J.
Deposit date:2003-12-13
Release date:2004-01-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Induced Fit Movements and Metal Cofactor Selectivity of Class II Aldolases: STRUCTURE OF THERMUS AQUATICUS FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE.
J.Biol.Chem., 279, 2004
1ZEN
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CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE
Descriptor:CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE
Authors:Cooper, S.J., Leonard, G.A., Hunter, W.N.
Deposit date:1996-07-08
Release date:1997-07-07
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of a class II fructose-1,6-bisphosphate aldolase shows a novel binuclear metal-binding active site embedded in a familiar fold.
Structure, 4, 1996
2FJK
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CRYSTAL STRUCTURE OF FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE IN THERMUS CALDOPHILUS
Descriptor:Fructose-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Lee, J.H., Im, Y.J., Rho, S.-H., Kim, M.-K., Kang, G.B., Eom, S.H.
Deposit date:2006-01-03
Release date:2006-08-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Stereoselectivity of fructose-1,6-bisphosphate aldolase in Thermus caldophilus
Biochem.Biophys.Res.Commun., 347, 2006
2ISV
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STRUCTURE OF GIARDIA FRUCTOSE-1,6-BIPHOSPHATE ALDOLASE IN COMPLEX WITH PHOSPHOGLYCOLOHYDROXAMATE
Descriptor:Putative fructose-1,6-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Galkin, A., Herzberg, O.
Deposit date:2006-10-18
Release date:2006-12-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Characterization, kinetics, and crystal structures of fructose-1,6-bisphosphate aldolase from the human parasite, Giardia lamblia.
J.Biol.Chem., 282, 2007
2ISW
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STRUCTURE OF GIARDIA FRUCTOSE-1,6-BIPHOSPHATE ALDOLASE IN COMPLEX WITH PHOSPHOGLYCOLOHYDROXAMATE
Descriptor:Putative fructose-1,6-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Galkin, A., Herzberg, O.
Deposit date:2006-10-18
Release date:2006-12-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Characterization, kinetics, and crystal structures of fructose-1,6-bisphosphate aldolase from the human parasite, Giardia lamblia.
J.Biol.Chem., 282, 2007
3C4U
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STRUCTURE OF CLASS II FRUCTOSE-BIPHOSPHATE ALDOLASE FROM HELICOBACTER PYLORI
Descriptor:Fructose-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Coincon, M., Sygusch, J.
Deposit date:2008-01-30
Release date:2008-08-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Synthesis and Biochemical Evaluation of Selective Inhibitors of Class II Fructose Bisphosphate Aldolases: Towards New Synthetic Antibiotics.
Chemistry, 14, 2008
3C52
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CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE FROM HELICOBACTER PYLORI IN COMPLEX WITH PHOSPHOGLYCOLOHYDROXAMIC ACID, A COMPETITIVE INHIBITOR
Descriptor:Fructose-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Coincon, M., Sygusch, J.
Deposit date:2008-01-30
Release date:2008-08-26
Modification date:2012-07-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Synthesis and Biochemical Evaluation of Selective Inhibitors of Class II Fructose Bisphosphate Aldolases: Towards New Synthetic Antibiotics.
Chemistry, 14, 2008
3C56
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CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE FROM HELICOBACTER PYLORI IN COMPLEX WITH N-(3-HYDROXYPROPYL)-GLYCOLOHYDROXAMIC ACID BISPHOSPHATE, A COMPETITIVE INHIBITOR
Descriptor:Fructose-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Coincon M., Sygusch,J., Potvin-Dulude, P.
Deposit date:2008-01-30
Release date:2008-08-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Synthesis and Biochemical Evaluation of Selective Inhibitors of Class II Fructose Bisphosphate Aldolases: Towards New Synthetic Antibiotics.
Chemistry, 14, 2008
3EKL
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STRUCTURAL CHARACTERIZATION OF TETRAMERIC MYCOBACTERIUM TUBERCULOSIS FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE - SUBSTRATE BINDING AND CATALYSIS MECHANISM OF A CLASS IIA BACTERIAL ALDOLASE
Descriptor:Fructose-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Pegan, S., Rukseree, K., Franzblau, S.G., Mesecar, A.D.
Deposit date:2008-09-19
Release date:2009-02-10
Modification date:2009-03-10
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis
J.Mol.Biol., 386, 2009
3EKZ
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STRUCTURAL CHARACTERIZATION OF TETRAMERIC MYCOBACTERIUM TUBERCULOSIS FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE - SUBSTRATE BINDING AND CATALYSIS MECHANISM OF A CLASS IIA BACTERIAL ALDOLASE
Descriptor:Fructose-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Pegan, S., Rukseree, K., Franzblau, S.G., Mesecar, A.D.
Deposit date:2008-09-19
Release date:2009-02-10
Modification date:2009-03-10
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis
J.Mol.Biol., 386, 2009
3ELF
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STRUCTURAL CHARACTERIZATION OF TETRAMERIC MYCOBACTERIUM TUBERCULOSIS FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE - SUBSTRATE BINDING AND CATALYSIS MECHANISM OF A CLASS IIA BACTERIAL ALDOLASE
Descriptor:Fructose-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Pegan, S., Rukseree, K., Franzblau, S.G., Mesecar, A.D.
Deposit date:2008-09-22
Release date:2009-02-10
Modification date:2010-06-23
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis
J.Mol.Biol., 386, 2009
3GAK
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STRUCTURE OF GIARDIA FRUCTOSE-1,6-BIPHOSPHATE ALDOLASE
Descriptor:Fructose-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Galkin, A., Herzberg, O.
Deposit date:2009-02-17
Release date:2009-03-31
Modification date:2010-06-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into the substrate binding and stereoselectivity of giardia fructose-1,6-bisphosphate aldolase.
Biochemistry, 48, 2009
3GB6
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STRUCTURE OF GIARDIA FRUCTOSE-1,6-BIPHOSPHATE ALDOLASE D83A MUTANT IN COMPLEX WITH FRUCTOSE-1,6-BISPHOSPHATE
Descriptor:Fructose-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Galkin, A., Herzberg, O.
Deposit date:2009-02-18
Release date:2009-03-31
Modification date:2010-06-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the substrate binding and stereoselectivity of giardia fructose-1,6-bisphosphate aldolase.
Biochemistry, 48, 2009
3N9R
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CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE FROM HELICOBACTER PYLORI IN COMPLEX WITH N-(4-HYDROXYBUTYL)-PHOSPHOGLYCOLOHYDROXAMIC ACID, A COMPETITIVE INHIBITOR
Descriptor:Fructose-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Coincon, M., Sygusch, S.
Deposit date:2010-05-31
Release date:2010-11-17
Modification date:2010-11-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Rational Design, Synthesis, and Evaluation of New Selective Inhibitors of Microbial Class II (Zinc Dependent) Fructose Bis-phosphate Aldolases.
J.Med.Chem., 53, 2010
3N9S
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CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE FROM HELICOBACTER PYLORI IN COMPLEX WITH N-(4-HYDROXYBUTYL)- GLYCOLOHYDROXAMIC ACID BIS-PHOSPHATE, A COMPETITIVE INHIBITOR
Descriptor:Fructose-bisphosphate aldolase (E.C.4.1.2.13 )
Authors:Coincon, M., Sygusch, S.
Deposit date:2010-05-31
Release date:2010-11-17
Modification date:2010-12-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Rational Design, Synthesis, and Evaluation of New Selective Inhibitors of Microbial Class II (Zinc Dependent) Fructose Bis-phosphate Aldolases.
J.Med.Chem., 53, 2010
3OHI
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STRUCTURE OF GIARDIA FRUCTOSE-1,6-BIPHOSPHATE ALDOLASE IN COMPLEX WITH 3-HYDROXY-2-PYRIDONE
Descriptor:Putative fructose-1,6-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Herzberg, O., Galkin, A.
Deposit date:2010-08-17
Release date:2011-01-19
Modification date:2011-03-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Rational design, synthesis and evaluation of first generation inhibitors of the Giardia lamblia fructose-1,6-biphosphate aldolase.
J.Inorg.Biochem., 105, 2010
3PM6
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CRYSTAL STRUCTURE OF A PUTATIVE FRUCTOSE-1,6-BIPHOSPHATE ALDOLASE FROM COCCIDIOIDES IMMITIS SOLVED BY COMBINED SAD MR
Descriptor:putative fructose-1,6-bisphosphate aldolase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-11-16
Release date:2010-12-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:SAD phasing using iodide ions in a high-throughput structural genomics environment.
J Struct Funct Genomics, 12, 2011
3Q94
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THE CRYSTAL STRUCTURE OF FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE FROM BACILLUS ANTHRACIS STR. 'AMES ANCESTOR'
Descriptor:Fructose-bisphosphate aldolase, class II (E.C.4.1.2.13)
Authors:Tan, K., Zhou, M., Kwon, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-01-07
Release date:2011-01-26
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:The crystal structure of fructose 1,6-bisphosphate aldolase from Bacillus anthracis str. 'Ames Ancestor'.
To be Published
3QM3
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1.85 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF FRUCTOSE-BISPHOSPHATE ALDOLASE (FBA) FROM CAMPYLOBACTER JEJUNI
Descriptor:Fructose-bisphosphate aldolase (E.C.4.1.2.13)
Authors:Minasov, G., Wawrzak, Z., Skarina, T., Onopriyenko, O., Papazisi, L., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-02-03
Release date:2011-02-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:1.85 Angstrom Resolution Crystal Structure of Fructose-bisphosphate Aldolase (Fba) from Campylobacter jejuni
TO BE PUBLISHED
4A21
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STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE BOUND TO SULFATE
Descriptor:FRUCTOSE-BISPHOSPHATE ALDOLASE (E.C.4.1.2.13)
Authors:Coincon, M., De La Paz Santangelo, M., Gest, P.M., Guerin, M.E., Pham, H., Ryan, G., Puckett, S.E., Spencer, J.S., Gonzalez-Juarrero, M., Daher, R., Lenaerts, A.J., Schnappinger, D., Therisod, M., Ehrt, S., Jackson, M., Sygusch, J.
Deposit date:2011-09-21
Release date:2011-10-05
Modification date:2011-11-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Glycolytic and Non-Glycolytic Functions of the Fructose-1,6-Bisphosphate Aldolase of Mycobacterium Tuberculosis, an Essential Enzyme Produced by Replicating and Non-Replicating Bacilli
J.Biol.Chem., 286, 2011
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