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2HCN
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2hcn
CRYSTAL STRUCTURE OF RNA DEPENDENT RNA POLYMERASE DOMAIN FROM WEST NILE VIRUS
Descriptor:RNA-directed RNA polymerase (NS5)
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-17
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
2HCS
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2hcs
CRYSTAL STRUCTURE OF RNA DEPENDANT RNA POLYMERASE DOMAIN OF WEST NILE VIRUS
Descriptor:RNA-directed RNA polymerase (NS5)
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-18
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
2HFZ
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2hfz
CRYSTAL STRUCTURE OF RNA DEPENDENT RNA POLYMERASE DOMAIN FROM WEST NILE VIRUS
Descriptor:RNA-directed RNA polymerase(NS5)
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-26
Release date:2007-02-06
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
2J7U
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2j7u
DENGUE VIRUS NS5 RNA DEPENDENT RNA POLYMERASE DOMAIN
Descriptor:RNA DEPENDENT RNA POLYMERASE
Authors:Yap, T.L., Xu, T., Chen, Y.L., Malet, H., Egloff, M.P., Canard, B., Vasudevan, S.G., Lescar, J.
Deposit date:2006-10-17
Release date:2007-03-13
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
2J7W
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2j7w
DENGUE VIRUS NS5 RNA DEPENDENT RNA POLYMERASE DOMAIN COMPLEXED WITH 3'DGTP
Descriptor:POLYPROTEIN
Authors:Yap, T.L., Xu, T., Chen, Y.L., Malet, H., Egloff, M.P., Canard, B., Vasudevan, S.G., Lescar, J.
Deposit date:2006-10-17
Release date:2007-03-13
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
3VWS
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3vws
DENGUE SEROTYPE 3 RNA-DEPENDENT RNA POLYMERASE BOUND TO NITD-107
Descriptor:Non-structural protein 5 (E.C.2.7.7.48)
Authors:Noble, C.G., Lescar, J.
Deposit date:2012-08-31
Release date:2013-02-27
Modification date:2013-07-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational flexibility of the Dengue virus RNA-dependent RNA polymerase revealed by a complex with an inhibitor
J.Virol., 87, 2013
4HDG
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4hdg
CRYSTAL STRUCTURE OF VIRAL RDRP IN COMPLEX WITH GTP
Descriptor:Polyprotein (E.C.2.7.7.48)
Authors:Surana, P., Nair, D.T.
Deposit date:2012-10-02
Release date:2013-12-25
Modification date:2014-03-12
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state.
Nucleic Acids Res., 42, 2014
4HDH
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4hdh
CRYSTAL STRUCTURE OF VIRAL RDRP IN COMPLEX WITH ATP
Descriptor:Polyprotein (E.C.2.7.7.48)
Authors:Surana, P., Nair, D.T.
Deposit date:2012-10-02
Release date:2013-12-25
Modification date:2014-03-12
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state.
Nucleic Acids Res., 42, 2014
4HHJ
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4hhj
DENGUE SEROTYPE 3 RNA-DEPENDENT RNA POLYMERASE
Descriptor:Non-structural protein 5 (E.C.2.7.7.48)
Authors:Noble, C.G., Lescar, J.
Deposit date:2012-10-10
Release date:2013-02-27
Modification date:2013-07-31
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Conformational flexibility of the Dengue virus RNA-dependent RNA polymerase revealed by a complex with an inhibitor
J.Virol., 87, 2013
4MTP
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4mtp
RDRP FROM JAPANESESE ENCEPHALITIS VIRUS
Descriptor:RNA dependent RNA polymerase (E.C.2.7.7.48)
Authors:Surana, P., Nair, D.T.
Deposit date:2013-09-20
Release date:2013-12-25
Modification date:2014-03-12
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state.
Nucleic Acids Res., 42, 2014
4C11
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4c11
DENGUE VIRUS RNA DEPENDENT RNA POLYMERASE WITH RESIDUES FROM THE NS5 LINKER REGION
Descriptor:DENGUE VIRUS TYPE 3 RNA DEPENDENT RNA POLYMERASE
Authors:Lim, S.P., Lescar, J.
Deposit date:2013-08-09
Release date:2013-08-21
Modification date:2013-11-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Crystal Structure of the Dengue Virus Ns5 Polymerase Delineates Inter-Domain Amino Acids Residues that Enhance its Thermostability and De Novo Initiation Activities.
J.Biol.Chem., 288, 2013
1L9K
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1l9k
DENGUE METHYLTRANSFERASE
Descriptor:RNA-DIRECTED RNA POLYMERASE (E.C.2.7.7.48)
Authors:Egloff, M.P., Benarroch, D., Selisko, B., Romette, J.L., Canard, B.
Deposit date:2002-03-25
Release date:2003-03-25
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An RNA cap (nucleoside-2'-O-) methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
Embo J., 21, 2002
1R6A
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1r6a
STRUCTURE OF THE DENGUE VIRUS 2'O METHYLTRANSFERASE IN COMPLEX WITH S-ADENOSYL HOMOCYSTEINE AND RIBAVIRIN 5' TRIPHOSPHATE
Descriptor:Genome polyprotein (E.C.2.7.7.48)
Authors:Benarroch, D., Egloff, M.P., Mulard, L., Romette, J.L., Canard, B.
Deposit date:2003-10-15
Release date:2004-09-21
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A structural basis for the inhibition of the NS5 dengue virus mRNA 2'-O-methyltransferase domain by ribavirin 5'-triphosphate.
J.Biol.Chem., 279, 2004
1S48
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1s48
CRYSTAL STRUCTURE OF RNA-DEPENDENT RNA POLYMERASE CONSTRUCT 1 (RESIDUES 71-679) FROM BVDV
Descriptor:RNA-dependent RNA polymerase
Authors:Choi, K.H., Groarke, J.M., Young, D.C., Kuhn, R.J., Smith, J.L., Pevear, D.C., Rossmann, M.G.
Deposit date:2004-01-15
Release date:2004-04-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1S49
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1s49
CRYSTAL STRUCTURE OF RNA-DEPENDENT RNA POLYMERASE CONSTRUCT 1 (RESIDUES 71-679) FROM BOVINE VIRAL DIARRHEA VIRUS COMPLEXED WITH GTP
Descriptor:RNA-dependent RNA polymerase
Authors:Choi, K.H., Groarke, J.M., Young, D.C., Kuhn, R.J., Smith, J.L., Pevear, D.C., Rossmann, M.G.
Deposit date:2004-01-15
Release date:2004-04-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1S4F
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1s4f
CRYSTAL STRUCTURE OF RNA-DEPENDENT RNA POLYMERASE CONSTRUCT 2 FROM BOVINE VIRAL DIARRHEA VIRUS (BVDV)
Descriptor:RNA-dependent RNA polymerase
Authors:Choi, K.H., Groarke, J.M., Young, D.C., Kuhn, R.J., Smith, J.L., Pevear, D.C., Rossmann, M.G.
Deposit date:2004-01-16
Release date:2004-04-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation.
Proc.Natl.Acad.Sci.Usa, 101, 2004
2CJQ
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2cjq
BOVINE VIRAL DIARRHEA VIRUS CP7-R12 RNA-DEPENDENT RNA POLYMERASE
Descriptor:RNA-DIRECTED RNA POLYMERASE (E.C.2.7.7.48)
Authors:Choi, K.H., Gallei, A., Becher, P., Rossmann, M.G.
Deposit date:2006-04-05
Release date:2006-07-19
Modification date:2009-06-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structure of Bovine Viral Diarrhea Virus RNA-Dependent RNA Polymerase and its Amino-Terminal Domain.
Structure, 14, 2006
2P1D
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2p1d
CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH GTP AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase (E.C.2.7.7.48)
Authors:Egloff, M.P., Benarooch, D., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-05
Release date:2007-03-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:An RNA cap (nucleoside-2'-O)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
EMBO J., 21, 2002
2P3L
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2p3l
CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH GPPPA AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase (E.C.2.7.7.48)
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-09
Release date:2007-08-28
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P3O
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2p3o
CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH 7MEGPPPA AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase (E.C.2.7.7.48)
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-09
Release date:2007-08-28
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.756 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P3Q
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2p3q
CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH GPPPG AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase (E.C.2.7.7.48)
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-09
Release date:2007-08-28
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P40
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2p40
CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH 7MEGPPPG
Descriptor:type II methyltransferase (E.C.2.7.7.48)
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-11
Release date:2007-08-28
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P41
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2p41
CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH 7MEGPPPG2'OME AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase (E.C.2.7.7.48)
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-11
Release date:2007-08-28
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
3LKZ
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3lkz
STRUCTURAL AND FUNCTIONAL ANALYSES OF A CONSERVED HYDROPHOBIC POCKET OF FLAVIVIRUS METHYLTRANSFERASE
Descriptor:Non-structural protein 5
Authors:Liu, L.H., Li, H.M.
Deposit date:2010-01-28
Release date:2010-08-04
Modification date:2011-01-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional analyses of a conserved hydrophobic pocket of flavivirus methyltransferase.
J.Biol.Chem., 285, 2010
4K6M
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4k6m
CRYSTAL STRUCTURE OF THE FULL-LENGTH JAPANESE ENCEPHALITIS VIRUS NS5
Descriptor:Polyprotein
Authors:Lu, G., Gong, P.
Deposit date:2013-04-16
Release date:2013-08-28
Modification date:2014-01-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the full-length Japanese encephalitis virus NS5 reveals a conserved methyltransferase-polymerase interface
Plos Pathog., 9, 2013
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entries available on 2014-10-22
00:00 UTC / 09:00 JST