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8T6U
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BU of 8t6u by Molmil
Cryo-EM structure of human Anion Exchanger 1 bound to Dipyridamole
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Capper, M.J, Zilberg, G, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D.
Deposit date:2023-06-18
Release date:2023-09-13
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Substrate binding and inhibition of the anion exchanger 1 transporter.
Nat.Struct.Mol.Biol., 30, 2023
8T6V
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BU of 8t6v by Molmil
Cryo-EM structure of human Anion Exchanger 1 bound to 4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid (DIDS)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid, ...
Authors:Capper, M.J, Zilberg, G, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D.
Deposit date:2023-06-18
Release date:2023-09-13
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Substrate binding and inhibition of the anion exchanger 1 transporter.
Nat.Struct.Mol.Biol., 30, 2023
8JNJ
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BU of 8jnj by Molmil
Structure of R932A/K1147A/H1148A mutant AE2
Descriptor: Anion exchange protein 2
Authors:Yin, Y.X, Ding, D.
Deposit date:2023-06-06
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural and functional insights into the lipid regulation of human anion exchanger 2.
Nat Commun, 15, 2024
8JNI
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BU of 8jni by Molmil
Structure of AE2 in complex with PIP2
Descriptor: Anion exchange protein 2, CHLORIDE ION, [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate
Authors:Yin, Y.X, Ding, D.
Deposit date:2023-06-06
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural and functional insights into the lipid regulation of human anion exchanger 2.
Nat Commun, 15, 2024
8GVE
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BU of 8gve by Molmil
The asymmetry structure of hAE2
Descriptor: Anion exchange protein 2
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-15
Release date:2023-04-12
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8GVF
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BU of 8gvf by Molmil
The outward-facing structure of hAE2 in basic pH
Descriptor: Anion exchange protein 2
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-15
Release date:2023-04-12
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8GVH
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BU of 8gvh by Molmil
Human AE2 in acidic KNO3
Descriptor: Anion exchange protein 2, CHOLESTEROL HEMISUCCINATE
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-15
Release date:2023-04-12
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8GVC
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BU of 8gvc by Molmil
The cryo-EM structure of hAE2 with bicarbonate
Descriptor: Anion exchange protein 2, BICARBONATE ION
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-14
Release date:2023-04-12
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8GVA
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BU of 8gva by Molmil
The intermediate structure of hAE2 in basic pH
Descriptor: Anion exchange protein 2
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-14
Release date:2023-04-12
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:The intermediate structure of hAE2 in basic pH
To Be Published
8GV9
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BU of 8gv9 by Molmil
The cryo-EM structure of hAE2 with chloride ion
Descriptor: Anion exchange protein 2, CHLORIDE ION
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-14
Release date:2023-04-12
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8GV8
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BU of 8gv8 by Molmil
The cryo-EM structure of hAE2 with DIDS
Descriptor: 2,2'-ethane-1,2-diylbis{5-[(sulfanylmethyl)amino]benzenesulfonic acid}, Anion exchange protein 2
Authors:Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
Deposit date:2022-09-14
Release date:2023-04-12
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8EEQ
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BU of 8eeq by Molmil
CryoEM structures of bAE1 captured in multiple states.
Descriptor: Anion exchange protein
Authors:Zhekova, H.R, Wang, W.G, Jiang, J.S, Tsirulnikov, K, Muhammad-Khan, G.H, Azimov, R, Abuladze, N, Kao, L, Newman, D, Noskov, S.Y, Tieleman, P, Zhou, Z.H, Pushkin, A, Kurtz, I.
Deposit date:2022-09-07
Release date:2023-01-25
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations.
Commun Biol, 5, 2022
8E34
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BU of 8e34 by Molmil
CryoEM structures of bAE1 captured in multiple states
Descriptor: Anion exchange protein
Authors:Zhekova, H.R, Wang, W.G, Jiang, J.S, Tsirulnikov, K, Muhammad-Khan, G.H, Azimov, R, Abuladze, N, Kao, L, Newman, D, Noskov, S.Y, Tieleman, P, Zhou, Z.H, Pushkin, A, Kurtz, I.
Deposit date:2022-08-16
Release date:2023-01-25
Method:ELECTRON MICROSCOPY (6 Å)
Cite:CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations.
Commun Biol, 5, 2022
8D9N
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BU of 8d9n by Molmil
CryoEM structures of bAE1 captured in multiple states.
Descriptor: Anion exchange protein
Authors:Zhekova, H.R, Wang, W.G, Jiang, J.S, Tsirulnikov, K, Muhammad-Khan, G.H, Azimov, R, Abuladze, N, Kao, L, Newman, D, Noskov, S.Y, Tieleman, P, Zhou, Z.H, Pushkin, A, Kurtz, I.
Deposit date:2022-06-10
Release date:2023-01-25
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations.
Commun Biol, 5, 2022
8CTE
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BU of 8cte by Molmil
Class 2 of erythrocyte ankyrin-1 complex (Composite map)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ammonium transporter Rh type A, Ankyrin-1, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-14
Release date:2022-07-20
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
8CT3
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BU of 8ct3 by Molmil
Local refinement of band3-I transmembrane region from class 2 of erythrocyte ankyrin-1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, CHOLESTEROL, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-13
Release date:2022-07-20
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
8CSY
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BU of 8csy by Molmil
Local refinement of cytoplasmic domains of band3-I in class 2 of erythrocyte ankyrin-1 complex
Descriptor: Band 3 anion transport protein
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-13
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
8CSV
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BU of 8csv by Molmil
Local refinement of Anykyrin-1 (N-terminal half of membrane binding domain) in Class 2 of erythrocyte ankyrin-1 complex
Descriptor: Ankyrin-1, Band 3 anion transport protein
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-13
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
8CS9
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BU of 8cs9 by Molmil
Composite reconstruction of Class 1 of the erythrocyte ankyrin-1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ammonium transporter Rh type A, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-12
Release date:2022-07-20
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
8CSL
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BU of 8csl by Molmil
Sub-tomogram averaging of erythrocyte ankyrin-1 complex
Descriptor: Ammonium transporter Rh type A, Ankyrin-1, Band 3 anion transport protein, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-12
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (25 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0Y
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BU of 7v0y by Molmil
Local refinement of Band 3-III cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex
Descriptor: Band 3 anion transport protein
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-11
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V19
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BU of 7v19 by Molmil
Local refinement of Band 3-II transmembrane domains, class 1 of erythrocyte ankyrin-1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, CHOLESTEROL, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-11
Release date:2022-07-20
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0T
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BU of 7v0t by Molmil
Local refinement of Band 3-I cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex
Descriptor: Band 3 anion transport protein
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-11
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0U
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BU of 7v0u by Molmil
Local refinement of Band 3-II cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex
Descriptor: Band 3 anion transport protein
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-11
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
8CRR
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BU of 8crr by Molmil
Local refinement of Band 3-III transmembrane domains, class 1 of erythrocyte ankyrin-1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, CHOLESTEROL, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-11
Release date:2022-07-20
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022

 

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