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1BKJ
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1bkj
NADPH:FMN OXIDOREDUCTASE FROM VIBRIO HARVEYI
Descriptor:NADPH-FLAVIN OXIDOREDUCTASE, FLAVIN MONONUCLEOTIDE
Authors:Tanner, J.J., Lei, B., TU, S.-C., Krause, K.L.
Deposit date:1998-07-08
Release date:1999-01-13
Modification date:2012-05-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Flavin reductase P: structure of a dimeric enzyme that reduces flavin.
Biochemistry, 35, 1996
1DS7
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1ds7
A MINOR FMN-DEPENDENT NITROREDUCTASE FROM ESCHERICHIA COLI B
Descriptor:FMN-DEPENDENT NITROREDUCTASE (E.C.1.6.99.7)
Authors:Parkinson, G., Skelly, J., Neidle, S.
Deposit date:2000-01-07
Release date:2000-07-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structure of FMN-dependent nitroreductase from Escherichia coli B: a prodrug-activating enzyme.
J.Med.Chem., 43, 2000
1F5V
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1f5v
STRUCTURE AND SITE-DIRECTED MUTAGENESIS OF A FLAVOPROTEIN FROM ESCHERICHIA COLI THAT REDUCES NITROCOMPOUNDS. ALTERATION OF PYRIDINE NUCLEOTIDE BINDING BY A SINGLE AMINO ACID SUBSTITUTION
Descriptor:OXYGEN-INSENSITIVE NADPH NITROREDUCTASE (E.C. 1.6.99.6)
Authors:Kobori, T., Sasaki, H., Lee, W.C., Zenno, S., Saigo, K., Murphy, M.E.P., Tanokura, M.
Deposit date:2000-06-17
Release date:2001-02-14
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and site-directed mutagenesis of a flavoprotein from Escherichia coli that reduces nitrocompounds: alteration of pyridine nucleotide binding by a single amino acid substitution.
J.Biol.Chem., 276, 2001
1ICR
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1icr
THE STRUCTURE OF ESCHERICHIA COLI NITROREDUCTASE COMPLEXED WITH NICOTINIC ACID
Descriptor:OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (E.C. 1.6.99.7)
Authors:Lovering, A.L., Hyde, E.I., Searle, P.F., White, S.A.
Deposit date:2001-04-02
Release date:2001-04-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The structure of Escherichia coli nitroreductase complexed with nicotinic acid: three crystal forms at 1.7 A, 1.8 A and 2.4 A resolution.
J.Mol.Biol., 309, 2001
1ICU
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1icu
THE STRUCTURE OF ESCHERICHIA COLI NITROREDUCTASE COMPLEXED WITH NICOTINIC ACID
Descriptor:OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (E.C. 1.6.99.7)
Authors:Lovering, A.L., Hyde, E.I., Searle, P.F., White, S.A.
Deposit date:2001-04-02
Release date:2001-04-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of Escherichia coli nitroreductase complexed with nicotinic acid: three crystal forms at 1.7 A, 1.8 A and 2.4 A resolution.
J.Mol.Biol., 309, 2001
1ICV
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1icv
THE STRUCTURE OF ESCHERICHIA COLI NITROREDUCTASE COMPLEXED WITH NICOTINIC ACID
Descriptor:OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (E.C. 1.6.99.7)
Authors:Lovering, A.L., Hyde, E.I., Searle, P.F., White, S.A.
Deposit date:2001-04-02
Release date:2001-04-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of Escherichia coli nitroreductase complexed with nicotinic acid: three crystal forms at 1.7 A, 1.8 A and 2.4 A resolution.
J.Mol.Biol., 309, 2001
1IDT
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1idt
STRUCTURAL STUDIES ON A PRODRUG-ACTIVATING SYSTEM-CB1954 AND FMN-DEPENDENT NITROREDUCTASE
Descriptor:MINOR FMN-DEPENDENT NITROREDUCTASE (E.C.1.6.99.7)
Authors:Johansson, E., Parkinson, G.N., Denny, W.A., Neidle, S.
Deposit date:2001-04-05
Release date:2003-09-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form.
J.Med.Chem., 46, 2003
1KQB
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1kqb
STRUCTURE OF NITROREDUCTASE FROM E. CLOACAE COMPLEX WITH INHIBITOR BENZOATE
Descriptor:OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (E.C.1.6.6.-)
Authors:Haynes, C.A., Koder, R.L., Miller, A.F., Rodgers, D.W.
Deposit date:2002-01-04
Release date:2002-02-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of nitroreductase in three states: effects of inhibitor binding and reduction.
J.Biol.Chem., 277, 2002
1KQC
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1kqc
STRUCTURE OF NITROREDUCTASE FROM E. CLOACAE COMPLEX WITH INHIBITOR ACETATE
Descriptor:OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (E.C.1.6.6.-)
Authors:Haynes, C.A., Koder, R.L., Miller, A.F., Rodgers, D.W.
Deposit date:2002-01-04
Release date:2002-02-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of nitroreductase in three states: effects of inhibitor binding and reduction.
J.Biol.Chem., 277, 2002
1KQD
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1kqd
STRUCTURE OF NITROREDUCTASE FROM E. CLOACAE BOUND WITH 2E-REDUCED FLAVIN MONONUCLEOTIDE (FMN)
Descriptor:OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE (E.C.1.6.6.-)
Authors:Haynes, C.A., Koder, R.L., Miller, A.F., Rodgers, D.W.
Deposit date:2002-01-04
Release date:2002-02-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of nitroreductase in three states: effects of inhibitor binding and reduction.
J.Biol.Chem., 277, 2002
1NEC
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1nec
NITROREDUCTASE FROM ENTEROBACTER CLOACAE
Descriptor:NITROREDUCTASE FROM ENTEROBACTER CLOACAE
Authors:Hecht, H.J., Bryant, C., Erdmann, H., Pelletier, H., Sawaya, R.
Deposit date:1999-03-30
Release date:2000-03-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of Nitroreductase from Enterobacter Cloacae
To be Published
1NOX
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1nox
NADH OXIDASE FROM THERMUS THERMOPHILUS
Descriptor:NADH OXIDASE, FLAVIN MONONUCLEOTIDE
Authors:Hecht, H.J., Erdmann, H., Park, H.J., Sprinzl, M., Schmid, R.D.
Deposit date:1996-11-20
Release date:1997-03-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Crystal structure of NADH oxidase from Thermus thermophilus.
Nat.Struct.Biol., 2, 1995
1OO5
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1oo5
STUDIES ON THE NITROREDUCTASE PRODRUG-ACTIVATING SYSTEM. CRYSTAL STRUCTURES OF THE ENZYME ACTIVE FORM AND COMPLEXES WITH THE INHIBITOR DICOUMAROL AND DINITROBENZAMIDE PRODRUGS
Descriptor:Oxygen-insensitive NAD(P)H nitroreductase (E.C.1.6.99.7)
Authors:Johansson, E., Parkinson, G.N., Denny, W.A., Neidle, S.
Deposit date:2003-03-03
Release date:2003-04-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form
J.Med.Chem., 46, 2003
1OO6
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1oo6
NITROREDUCTASE FROM E-COLI IN COMPLEX WITH THE DINITROBENZAMIDE PRODRUG SN23862
Descriptor:Oxygen-insensitive NAD(P)H nitroreductase (E.C.1.6.99.7)
Authors:Johansson, E., Parkinson, G.N., Denny, W.A., Neidle, S.
Deposit date:2003-03-03
Release date:2003-04-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form
J.Med.Chem., 46, 2003
1OON
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1oon
NITROREDUCTASE FROM E-COLI IN COMPLEX WITH THE DINITROBENZAMIDE PRODRUG SN27217
Descriptor:Oxygen-insensitive NAD(P)H nitroreductase (E.C.1.6.99.7)
Authors:Johansson, E., Parkinson, G.N., Denny, W.A., Neidle, S.
Deposit date:2003-03-04
Release date:2003-04-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form
J.Med.Chem., 46, 2003
1OOQ
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1ooq
NITROREDUCTASE FROM E-COLI IN COMPLEX WITH THE INHIBITOR DICOUMAROL
Descriptor:Oxygen-insensitive NAD(P)H nitroreductase (E.C.1.6.99.7)
Authors:Johansson, E., Parkinson, G.N., Denny, W.A., Neidle, S.
Deposit date:2003-03-04
Release date:2003-04-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form
J.Med.Chem., 46, 2003
1V5Y
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1v5y
BINDING OF COUMARINS TO NAD(P)H:FMN OXIDOREDUCTASE
Descriptor:Major NAD(P)H-flavin oxidoreductase (E.C.1.6.99.-)
Authors:Kobori, T., Koike, H., Sasaki, H., Zenno, S., Saigo, K., Tanokura, M.
Deposit date:2003-11-26
Release date:2005-03-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Binding of coumarins to NAD(P)H:FMN oxidoreductase
To be Published
1V5Z
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1v5z
BINDING OF COUMARINS TO NAD(P)H:FMN OXIDOREDUCTASE
Descriptor:Major NAD(P)H-flavin oxidoreductase (E.C.1.6.99.-)
Authors:Kobori, T., Koike, H., Sasaki, H., Zenno, S., Saigo, K., Tanokura, M.
Deposit date:2003-11-26
Release date:2005-03-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of coumarins to NAD(P)H:FMN oxidoreductase
To be Published
1VFR
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1vfr
THE MAJOR NAD(P)H:FMN OXIDOREDUCTASE FROM VIBRIO FISCHERI
Descriptor:NAD(P)H\:FMN OXIDOREDUCTASE, FLAVIN MONONUCLEOTIDE
Authors:Koike, H., Sasaki, H., Kobori, T., Zenno, S., Saigo, K., Murphy, M.E.P., Adman, E.T., Tanokura, M.
Deposit date:1998-01-09
Release date:1999-02-16
Modification date:2012-05-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:1.8 A crystal structure of the major NAD(P)H:FMN oxidoreductase of a bioluminescent bacterium, Vibrio fischeri: overall structure, cofactor and substrate-analog binding, and comparison with related flavoproteins.
J.Mol.Biol., 280, 1998
1YKI
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1yki
THE STRUCTURE OF E. COLI NITROREDUCTASE BOUND WITH THE ANTIBIOTIC NITROFURAZONE
Descriptor:Oxygen-insensitive NAD(P)H nitroreductase (E.C.1.5.1.34)
Authors:Race, P.R., Lovering, A.L., Green, R.M., Ossor, A., White, S.A., Searle, P.F., Wrighton, C.J., Hyde, E.I.
Deposit date:2005-01-18
Release date:2005-02-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.
J.Biol.Chem., 280, 2005
1YLR
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1ylr
THE STRUCTURE OF E.COLI NITROREDUCTASE WITH BOUND ACETATE, CRYSTAL FORM 1
Descriptor:Oxygen-insensitive NAD(P)H nitroreductase (E.C.1.5.1.34)
Authors:Race, P.R., Lovering, A.L., Green, R.M., Ossor, A., White, S.A., Searle, P.F., Wrighton, C.J., Hyde, E.I.
Deposit date:2005-01-19
Release date:2005-02-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.
J.Biol.Chem., 280, 2005
1YLU
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1ylu
THE STRUCTURE OF E. COLI NITROREDUCTASE WITH BOUND ACETATE, CRYSTAL FORM 2
Descriptor:Oxygen-insensitive NAD(P)H nitroreductase (E.C.1.5.1.34)
Authors:Race, P.R., Lovering, A.L., Green, R.M., Ossor, A., White, S.A., Searle, P.F., Wrighton, C.J., Hyde, E.I.
Deposit date:2005-01-19
Release date:2005-02-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.
J.Biol.Chem., 280, 2005
1YWQ
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1ywq
CRYSTAL STRUCTURE OF A NITROREDUCTASE FAMILY PROTEIN FROM BACILLUS CEREUS ATCC 14579
Descriptor:Nitroreductase family protein
Authors:Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-02-18
Release date:2005-04-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a nitroreductase family protein from Bacillus cereus ATCC 14579
To be Published
1ZCH
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1zch
STRUCTURE OF THE HYPOTHETICAL OXIDOREDUCTASE YCND FROM BACILLUS SUBTILIS
Descriptor:Hypothetical oxidoreductase ycnD (E.C.1.-.-.-)
Authors:Morokutti, A., Lyskowski, A., Sollner, S., Pointner, E., Fitzpatrick, T.B., Kratky, C., Gruber, K., Macheroux, P.
Deposit date:2005-04-12
Release date:2005-11-01
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure and Function of YcnD from Bacillus subtilis, a Flavin-Containing Oxidoreductase(,).
Biochemistry, 44, 2005
2B67
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2b67
CRYSTAL STRUCTURE OF THE NITROREDUCTASE FAMILY PROTEIN FROM STREPTOCOCCUS PNEUMONIAE TIGR4
Descriptor:COG0778: Nitroreductase
Authors:Kim, Y., Volkart, L., Abdullah, J., Collart, F., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-09-30
Release date:2005-11-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of the Nitroreductase Family Protein from Streptococcus pneumoniae TIGR4
To be Published
<123>
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