3H9V
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CRYSTAL STRUCTURE OF THE ATP-GATED P2X4 ION CHANNEL IN THE CLOSED, APO STATE AT 3.1 ANGSTROMS
Descriptor:P2X purinoceptor
Authors:Kawate, T., Michel, J.C., Gouaux, E.
Deposit date:2009-04-30
Release date:2009-07-28
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the ATP-gated P2X(4) ion channel in the closed state.
Nature, 460, 2009
3I5D
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CRYSTAL STRUCTURE OF THE ATP-GATED P2X4 ION CHANNEL IN THE CLOSED, APO STATE AT 3.5 ANGSTROMS (R3)
Descriptor:P2X purinoceptor
Authors:Kawate, T., Michel, J.C., Gouaux, E.
Deposit date:2009-07-05
Release date:2009-08-04
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.46 Å)
Cite:Crystal structure of the ATP-gated P2X(4) ion channel in the closed state.
Nature, 460, 2009
4DW0
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CRYSTAL STRUCTURE OF THE ATP-GATED P2X4 ION CHANNEL IN THE CLOSED, APO STATE AT 2.9 ANGSTROMS
Descriptor:P2X purinoceptor
Authors:Hattori, M., Gouaux, E.
Deposit date:2012-02-24
Release date:2012-04-25
Modification date:2013-01-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular mechanism of ATP binding and ion channel activation in P2X receptors.
Nature, 485, 2012
4DW1
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CRYSTAL STRUCTURE OF THE ATP-GATED P2X4 ION CHANNEL IN THE ATP-BOUND, OPEN STATE AT 2.8 ANGSTROMS
Descriptor:P2X purinoceptor
Authors:Hattori, M., Gouaux, E.
Deposit date:2012-02-24
Release date:2012-04-25
Modification date:2013-01-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular mechanism of ATP binding and ion channel activation in P2X receptors.
Nature, 485, 2012
5F1C
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CRYSTAL STRUCTURE OF AN INVERTEBRATE P2X RECEPTOR FROM THE GULF COAST TICK IN THE PRESENCE OF ATP AND ZN2+ ION AT 2.9 ANGSTROMS
Descriptor:Putative uncharacterized protein
Authors:Kasuya, G., Hattori, M., Ishitani, R., Nureki, O.
Deposit date:2015-11-30
Release date:2016-03-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Insights into Divalent Cation Modulations of ATP-Gated P2X Receptor Channels
Cell Rep, 14, 2016
5SVJ
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL IN THE CLOSED, APO STATE
Descriptor:P2X purinoceptor 3
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-06
Release date:2016-09-28
Modification date:2016-10-19
Method:X-RAY DIFFRACTION (2.984 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVK
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL IN THE ATP-BOUND, OPEN STATE
Descriptor:P2X purinoceptor 3
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-06
Release date:2016-09-28
Modification date:2016-10-19
Method:X-RAY DIFFRACTION (2.773 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVL
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL IN THE ATP-BOUND, CLOSED (DESENSITIZED) STATE
Descriptor:P2X purinoceptor 3
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-06
Release date:2016-10-05
Modification date:2016-10-19
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVM
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL BOUND TO AGONIST 2-METHYLTHIO-ATP IN THE DESENSITIZED STATE
Descriptor:P2X purinoceptor 3
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-06
Release date:2016-09-28
Modification date:2016-10-19
Method:X-RAY DIFFRACTION (3.093 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVP
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ANOMALOUS SULFUR SIGNAL REVEALS THE POSITION OF AGONIST 2-METHYLTHIO-ATP BOUND TO THE ATP-GATED HUMAN P2X3 ION CHANNEL IN THE DESENSITIZED STATE
Descriptor:P2X purinoceptor 3
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-09-28
Modification date:2016-10-19
Method:X-RAY DIFFRACTION (3.298 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVQ
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL BOUND TO COMPETITIVE ANTAGONIST TNP-ATP
Descriptor:P2X purinoceptor 3
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-10-05
Modification date:2016-10-19
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVR
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL BOUND TO COMPETITIVE ANTAGONIST A-317491
Descriptor:P2X purinoceptor 3
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-10-05
Modification date:2016-10-19
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVS
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ANOMALOUS MN2+ SIGNAL REVEALS A DIVALENT CATION-BINDING SITE IN THE HEAD DOMAIN OF THE ATP-GATED HUMAN P2X3 ION CHANNEL
Descriptor:P2X purinoceptor 3
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-09-28
Modification date:2016-10-19
Method:X-RAY DIFFRACTION (4.025 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVT
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ANOMALOUS CS+ SIGNAL REVEALS THE SITE OF NA+ ION ENTRY TO THE CHANNEL PORE OF THE HUMAN P2X3 ION CHANNEL THROUGH THE EXTRACELLULAR FENESTRATIONS
Descriptor:P2X purinoceptor 3
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-09-28
Modification date:2016-10-19
Method:X-RAY DIFFRACTION (3.794 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
2RUP
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SOLUTION STRUCTURE OF RAT P2X4 RECEPTOR HEAD DOMAIN
Descriptor:P2X purinoceptor 4
Authors:Abe, Y., Igawa, T., Tsuda, M., Inoue, K., Ueda, T.
Deposit date:2014-11-12
Release date:2015-02-04
Method:SOLUTION NMR
Cite:Solution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding
Febs Lett., 2015
2BP5
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MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH NON-CANONICAL INTERNALIZATION PEPTIDE VEDYEQGLSG
Descriptor:CLATHRIN COAT ASSEMBLY PROTEIN AP50, P2X PURINOCEPTOR 4
Authors:Royle, S.J., Evans, P.R., Owen, D.J., Murrell-Lagnado, R.D.
Deposit date:2005-04-18
Release date:2005-07-06
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Non-Canonical Yxxg-Phi Endocytic Motifs: Recognition by Ap2 and Preferential Utilization in P2X4 Receptors.
J.Cell.Sci, 118, 2005
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