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1IKO
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1iko
CRYSTAL STRUCTURE OF THE MURINE EPHRIN-B2 ECTODOMAIN
Descriptor:EPHRIN-B2
Authors:Toth, J., Cutforth, T., Gelinas, A.D., Bethoney, K.A., Bard, J., Harrison, C.J.
Deposit date:2001-05-03
Release date:2002-05-03
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of an ephrin ectodomain.
Dev.Cell, 1, 2001
1SHX
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1shx
EPHRIN A5 LIGAND STRUCTURE
Descriptor:Ephrin-A5
Authors:Himanen, J.P., Barton, W.A., Nikolov, D.B., Jeffrey, P.D.
Deposit date:2004-02-26
Release date:2005-04-19
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3.
J.Biol.Chem., 280, 2005
2I85
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2i85
NMR SOLUTION STRUCTURE OF HUMAN EPHRINB2 ECTODOMAIN
Descriptor:Ephrin-B2
Authors:Ran, X., Fan, J., Song, J.
Deposit date:2006-09-01
Release date:2007-09-04
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:NMR solution structure of Human ephrinB2 ectodomain
To be published
1SHW
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1shw
EPHB2 / EPHRINA5 COMPLEX STRUCTURE
Descriptor:Ephrin-A5/Ephrin type-B receptor 2
Authors:Himanen, J.P., Chumley, M.J., Lackmann, M., Li, C., Barton, W.A., Jeffrey, P.D., Vearing, C., Geleick, D., Feldheim, D.A., Boyd, A.W.
Deposit date:2004-02-26
Release date:2004-05-18
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling
Nat.Neurosci., 7, 2004
1KGY
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1kgy
CRYSTAL STRUCTURE OF THE EPHB2-EPHRINB2 COMPLEX
Descriptor:EPHRIN TYPE-B RECEPTOR 2 (E.C.2.7.1.112), EPHRIN-B2
Authors:Himanen, J-P., Rajashankar, K.R., Lackmann, M., Cowan, C.A., Henkemeyer, M., Nikolov, D.B.
Deposit date:2001-11-28
Release date:2002-05-28
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of an Eph receptor-ephrin complex.
Nature, 414, 2001
2HLE
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2hle
STRUCTURAL AND BIOPHYSICAL CHARACTERIZATION OF THE EPHB4-EPHRINB2 PROTEIN PROTEIN INTERACTION AND RECEPTOR SPECIFICITY.
Descriptor:Ephrin type-B receptor 4 (E.C.2.7.10.1), Ephrin-B2
Authors:Chrencik, J.E., Brooun, A., Kuhn, P., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
Deposit date:2006-07-06
Release date:2006-08-22
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural and Biophysical Characterization of the EphB4-EphrinB2 Protein-Protein Interaction and Receptor Specificity.
J.Biol.Chem., 281, 2006
2VSK
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2vsk
HENDRA VIRUS ATTACHMENT GLYCOPROTEIN IN COMPLEX WITH HUMAN CELL SURFACE RECEPTOR EPHRINB2
Descriptor:HEMAGGLUTININ-NEURAMINIDASE (E.C.3.2.1.18), EPHRIN-B2
Authors:Bowden, T.A., Aricescu, A.R., Gilbert, R.J., Grimes, J.M., Jones, E.Y., Stuart, D.I.
Deposit date:2008-04-24
Release date:2008-05-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Basis of Nipah and Hendra Virus Attachment to Their Cell-Surface Receptor Ephrin-B2
Nat.Struct.Mol.Biol., 15, 2008
2VSM
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2vsm
NIPAH VIRUS ATTACHMENT GLYCOPROTEIN IN COMPLEX WITH HUMAN CELL SURFACE RECEPTOR EPHRINB2
Descriptor:HEMAGGLUTININ-NEURAMINIDASE (E.C.3.2.1.18), EPHRIN-B2
Authors:Bowden, T.A., Aricescu, A.R., Gilbert, R.J., Grimes, J.M., Jones, E.Y., Stuart, D.I.
Deposit date:2008-04-25
Release date:2008-05-20
Modification date:2009-04-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of Nipah and Hendra Virus Attachment to Their Cell-Surface Receptor Ephrin-B2
Nat.Struct.Mol.Biol., 15, 2008
2WO2
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2wo2
CRYSTAL STRUCTURE OF THE EPHA4-EPHRINB2 COMPLEX
Descriptor:EPHRIN TYPE-A RECEPTOR (E.C.2.7.10.1), EPHRIN-B2
Authors:Bowden, T.A., Aricescu, A.R., Nettleship, J.E., Siebold, C., Rahman-Huq, N., Owens, R.J., Stuart, D.I., Jones, E.Y.
Deposit date:2009-07-21
Release date:2009-10-27
Modification date:2011-11-09
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural Plasticity of Eph-Receptor A4 Facilitates Cross-Class Ephrin Signalling
Structure, 17, 2009
2WO3
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2wo3
CRYSTAL STRUCTURE OF THE EPHA4-EPHRINA2 COMPLEX
Descriptor:EPHRIN TYPE-A RECEPTOR (E.C.2.7.10.1), EPHRIN-A2
Authors:Bowden, T.A., Aricescu, A.R., Nettleship, J.E., Siebold, C., Rahman-Huq, N., Owens, R.J., Stuart, D.I., Jones, E.Y.
Deposit date:2009-07-21
Release date:2009-10-27
Modification date:2011-11-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Plasticity of Eph-Receptor A4 Facilitates Cross-Class Ephrin Signalling
Structure, 17, 2009
2X11
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2x11
CRYSTAL STRUCTURE OF THE COMPLETE EPHA2 ECTODOMAIN IN COMPLEX WITH EPHRIN A5 RECEPTOR BINDING DOMAIN
Descriptor:EPHRIN TYPE-A RECEPTOR 2 (E.C.2.7.10.1), EPHRIN-A5
Authors:Seiradake, E., Harlos, K., Sutton, G., Aricescu, A.R., Jones, E.Y.
Deposit date:2009-12-21
Release date:2010-03-16
Modification date:2011-08-31
Method:X-RAY DIFFRACTION (4.83 Å)
Cite:An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly
Nat.Struct.Mol.Biol., 17, 2010
3D12
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3d12
CRYSTAL STRUCTURES OF NIPAH VIRUS G ATTACHMENT GLYCOPROTEIN IN COMPLEX WITH ITS RECEPTOR EPHRIN-B3
Descriptor:Crystal Structures of the Nipah G Attachment Glycoprotein and its Complex with Ephrin-B3
Authors:Xu, K., Rajashankar, K.R., Chan, Y.P., Himanen, P., Broder, C.C., Nikolov, D.B.
Deposit date:2008-05-02
Release date:2008-08-19
Modification date:2014-02-12
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3.
Proc.Natl.Acad.Sci.USA, 105, 2008
3GXU
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3gxu
CRYSTAL STRUCTURE OF EPH RECEPTOR AND EPHRIN COMPLEX
Descriptor:Ephrin type-A receptor 4, Ephrin-B2
Authors:Qin, H.N., Song, J.X.
Deposit date:2009-04-03
Release date:2009-10-27
Modification date:2009-11-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural characterization of the EphA4-ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity
J.Biol.Chem., 2009
3HEI
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3hei
LIGAND RECOGNITION BY A-CLASS EPH RECEPTORS: CRYSTAL STRUCTURES OF THE EPHA2 LIGAND-BINDING DOMAIN AND THE EPHA2/EPHRIN-A1 COMPLEX
Descriptor:Ephrin type-A receptor 2 (E.C.2.7.10.1), Ephrin-A1
Authors:Himanen, J.P., Goldgur, Y., Miao, H., Myshkin, E., Guo, H., Buck, M., Nguyen, M., Rajashankar, K.R., Wang, B., Nikolov, D.B.
Deposit date:2009-05-08
Release date:2009-06-30
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex.
Embo Rep., 10, 2009
3MBW
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3mbw
CRYSTAL STRUCTURE OF THE HUMAN EPHRIN A2 LBD AND CRD DOMAINS IN COMPLEX WITH EPHRIN A1
Descriptor:Crystal structure of the human ephrin A2 LBD and CRD domains complex with ephrin A1
Authors:Walker, J.R., Yermekbayeva, L., Seitova, A., Butler-Cole, C., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2010-03-26
Release date:2010-06-09
Modification date:2010-06-30
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MX0
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3mx0
CRYSTAL STRUCTURE OF EPHA2 ECTODOMAIN IN COMPLEX WITH EPHRIN-A5
Descriptor:Ephrin type-A receptor 2 (E.C.2.7.10.1), Ephrin-A5
Authors:Himanen, J.P., Yermekbayeva, L., Janes, P.W., Walker, J.R., Xu, K., Atapattu, L., Rajashankar, K.R., Mensinga, A., Lackmann, M., Nikolov, D.B., Dhe-Paganon, S.
Deposit date:2010-05-06
Release date:2010-06-30
Method:X-RAY DIFFRACTION (3.506 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
4BK5
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4bk5
CRYSTAL STRUCTURE OF THE HUMAN EPHA4 ECTODOMAIN IN COMPLEX WITH HUMAN EPHRIN A5 (AMINE-METHYLATED SAMPLE)
Descriptor:EPHRIN TYPE-A RECEPTOR 4 (E.C.2.7.10.1), EPHRIN-A5 (E.C.2.7.10.1)
Authors:Seiradake, E., Schaupp, A., del Toro Ruiz, D., Kaufmann, R., Mitakidis, N., Harlos, K., Aricescu, A.R., Klein, R., Jones, E.Y.
Deposit date:2013-04-22
Release date:2013-07-03
Modification date:2013-08-21
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4BKA
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4bka
CRYSTAL STRUCTURE OF THE HUMAN EPHA4 ECTODOMAIN IN COMPLEX WITH HUMAN EPHRIN A5
Descriptor:EPHRIN TYPE-A RECEPTOR 4 (E.C.2.7.10.1), EPHRIN-A5
Authors:Seiradake, E., Schaupp, A., del Toro Ruiz, D., Kaufmann, R., Mitakidis, N., Harlos, K., Aricescu, A.R., Klein, R., Jones, E.Y.
Deposit date:2013-04-23
Release date:2013-07-03
Modification date:2013-09-04
Method:X-RAY DIFFRACTION (5.3 Å)
Cite:Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4BKF
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4bkf
CRYSTAL STRUCTURE OF THE HUMAN EPHA4 ECTODOMAIN IN COMPLEX WITH HUMAN EPHRINB3
Descriptor:EPHRIN TYPE-A RECEPTOR 4 (E.C.2.7.10.1), EPHRIN-B3
Authors:Seiradake, E., Schaupp, A., del Toro Ruiz, D., Kaufmann, R., Mitakidis, N., Harlos, K., Aricescu, A.R., Klein, R., Jones, E.Y.
Deposit date:2013-04-24
Release date:2013-07-03
Modification date:2013-08-21
Method:X-RAY DIFFRACTION (4.65 Å)
Cite:Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4L0P
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4l0p
STRUCTURE OF THE HUMAN EPHA3 RECEPTOR LIGAND BINDING DOMAIN COMPLEXED WITH EPHRIN-A5
Descriptor:Ephrin type-A receptor 3, Ephrin-A5
Authors:Forse, G.J., Kolatkar, A.R., Kuhn, P.
Deposit date:2013-05-31
Release date:2014-06-11
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Cancer-specific Somatic Mutations Result in Structural and Thermodynamic Changes in the EphA3 Receptor
To be Published
4M4R
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4m4r
EPHA4 ECTODOMAIN COMPLEX WITH EPHRIN A5
Descriptor:Ephrin type-A receptor 4 (E.C.2.7.10.1), Ephrin-A5
Authors:Xu, K., Tsvetkova-Robev, D., Xu, Y., Goldgur, Y., Chan, Y.-P., Himanen, J.P., Nikolov, D.B.
Deposit date:2013-08-07
Release date:2013-10-30
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.
Proc.Natl.Acad.Sci.USA, 110, 2013
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entries available on 2014-12-17
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