1BR0
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THREE DIMENSIONAL STRUCTURE OF THE N-TERMINAL DOMAIN OF SYNTAXIN 1A
Descriptor:SYNTAXIN 1-A
Authors:Fernandez, I., Ubach, J., Dubulova, I., Zhang, X., Sudhof, T.C., Rizo, J.
Deposit date:1998-08-25
Release date:1998-09-02
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A.
Cell(Cambridge,Mass.), 94, 1998
1EZ3
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CRYSTAL STRUCTURE OF THE NEURONAL T-SNARE SYNTAXIN-1A
Descriptor:SYNTAXIN-1A
Authors:Lerman, J.C., Robblee, J., Fairman, R., Hughson, F.M.
Deposit date:2000-05-09
Release date:2000-06-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of the neuronal SNARE protein syntaxin-1A.
Biochemistry, 39, 2000
1FIO
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CRYSTAL STRUCTURE OF YEAST T-SNARE PROTEIN SSO1
Descriptor:SSO1 PROTEIN
Authors:Munson, M., Chen, X., Cocina, A.E., Schultz, S.M., Hughson, F.M.
Deposit date:2000-08-04
Release date:2000-10-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Interactions within the yeast t-SNARE Sso1p that control SNARE complex assembly.
Nat.Struct.Biol., 7, 2000
1HVV
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SELF-ASSOCIATION OF THE H3 REGION OF SYNTAXIN 1A: IMPLICATIONS FOR SNARE COMPLEX ASSEMBLY
Descriptor:SYNTAXIN 1A
Authors:Misura, K.M.S., Scheller, R.H., Weis, W.I.
Deposit date:2001-01-08
Release date:2001-01-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Self-association of the H3 region of syntaxin 1A. Implications for intermediates in SNARE complex assembly.
J.Biol.Chem., 276, 2001
1JTH
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CRYSTAL STRUCTURE AND BIOPHYSICAL PROPERTIES OF A COMPLEX BETWEEN THE N-TERMINAL REGION OF SNAP25 AND THE SNARE REGION OF SYNTAXIN 1A
Descriptor:SNAP25/syntaxin 1a
Authors:Misura, K.M.S., Gonzalez Jr., L.C., May, A.P., Scheller, R.H., Weis, W.I.
Deposit date:2001-08-21
Release date:2001-11-28
Modification date:2014-04-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure and biophysical properties of a complex between the N-terminal SNARE region of SNAP25 and syntaxin 1a.
J.Biol.Chem., 276, 2001
1URQ
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CRYSTAL STRUCTURE OF NEURONAL Q-SNARES IN COMPLEX WITH R-SNARE MOTIF OF TOMOSYN
Descriptor:M-TOMOSYN ISOFORM, SYNTAXIN 1A, SYNAPTOSOMAL-ASSOCIATED PROTEIN 25
Authors:Pobbati, A., Razeto, A., Becker, S., Fasshauer, D.
Deposit date:2003-10-31
Release date:2004-08-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Inhibitory Role of Tomosyn in Exocytosis
J.Biol.Chem., 279, 2004
2M8R
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PRE-FUSION SOLUTION NMR STRUCTURE OF NEURONAL SNARE SYNTAXIN 1A
Descriptor:Syntaxin-1A
Authors:Liang, B., Kiessling, V., Tamm, L.K.
Deposit date:2013-05-24
Release date:2013-11-20
Modification date:2013-12-11
Method:SOLUTION NMR
Cite:Prefusion structure of syntaxin-1A suggests pathway for folding into neuronal trans-SNARE complex fusion intermediate.
Proc.Natl.Acad.Sci.USA, 110, 2013
3LG7
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CRYSTAL STRUCTURE OF HIV EPITOPE-SCAFFOLD 4E10_S0_1EZ3A_002_C
Descriptor:4E10_S0_1EZ3A_002_C (T246)
Authors:Holmes, M.A.
Deposit date:2010-01-19
Release date:2010-09-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
1KIL
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THREE-DIMENSIONAL STRUCTURE OF THE COMPLEXIN/SNARE COMPLEX
Descriptor:Synaptobrevin SNARE motif, Syntaxin SNARE motif short, SNAP-25 N-terminal SNARE motif, SNAP-25 C-terminal SNARE motif, Complexin I SNARE-complex binding region
Authors:Chen, X., Tomchick, D., Kovrigin, E., Arac, D., Machius, M., Sudhof, T.C., Rizo, J.
Deposit date:2001-12-03
Release date:2002-03-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three-dimensional structure of the complexin/SNARE complex.
Neuron, 33, 2002
1N7S
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HIGH RESOLUTION STRUCTURE OF A TRUNCATED NEURONAL SNARE COMPLEX
Descriptor:vesicle-associated membrane protein 2/Syntaxin 1A/SNAP-25A
Authors:Ernst, J.A., Brunger, A.T.
Deposit date:2002-11-16
Release date:2002-12-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:High Resolution Structure, Stability, and Synaptotagmin Binding of a Truncated Neuronal SNARE Complex
J.Biol.Chem., 278, 2003
1SFC
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NEURONAL SYNAPTIC FUSION COMPLEX
Descriptor:PROTEIN (SYNAPTOBREVIN 2)
Authors:Sutton, R.B., Brunger, A.T.
Deposit date:1998-08-24
Release date:1998-10-28
Modification date:2013-10-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution.
Nature, 395, 1998
2N1T
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DYNAMIC BINDING MODE OF A SYNAPTOTAGMIN-1-SNARE COMPLEX IN SOLUTION
Descriptor:Vesicle-associated membrane protein 2, Syntaxin-1A, Synaptosomal-associated protein 25, Synaptotagmin-1
Authors:Brewer, K., Bacaj, T., Cavalli, A., Camilloni, C., Swarbrick, J., Liu, J., Zhou, A., Zhou, P., Barlow, N., Xu, J., Seven, A., Prinslow, E., Voleti, R., Haussinger, D., Bonvin, A., Tomchick, D., Vendruscolo, M., Graham, B., Sudhof, T., Rizo, J.
Deposit date:2015-04-21
Release date:2015-06-03
Modification date:2015-07-22
Method:SOLUTION NMR
Cite:Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution.
Nat.Struct.Mol.Biol., 22, 2015
2XHE
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CRYSTAL STRUCTURE OF THE UNC18-SYNTAXIN 1 COMPLEX FROM MONOSIGA BREVICOLLIS
Descriptor:UNC18, SYNTAXIN1
Authors:Burkhardt, P., Stegmann, C.M., Wahl, M.C., Fasshauer, D.
Deposit date:2010-06-14
Release date:2011-06-29
Modification date:2012-03-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Primordial Neurosecretory Apparatus Identified in the Choanoflagellate Monosiga Brevicollis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3B5N
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STRUCTURE OF THE YEAST PLASMA MEMBRANE SNARE COMPLEX
Descriptor:Synaptobrevin homolog 1, Protein SSO1, Protein transport protein SEC9
Authors:Strop, P., Brunger, A.T.
Deposit date:2007-10-26
Release date:2007-11-20
Modification date:2009-05-19
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Structure of the Yeast Plasma Membrane SNARE Complex Reveals Destabilizing Water-filled Cavities.
J.Biol.Chem., 283, 2008
3C98
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REVISED STRUCTURE OF THE MUNC18A-SYNTAXIN1 COMPLEX
Descriptor:Syntaxin-binding protein 1, Syntaxin-1A
Authors:Hattendorf, D.A., Misura, K.M., Burkhardt, P., Scheller, R.H., Fasshauer, D., Weis, W.I.
Deposit date:2008-02-15
Release date:2008-03-25
Modification date:2009-05-19
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide
Embo J., 27, 2008
3HD7
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HELICAL EXTENSION OF THE NEURONAL SNARE COMPLEX INTO THE MEMBRANE, SPACEGROUP C 1 2 1
Descriptor:Vesicle-associated membrane protein 2, Syntaxin-1A, Synaptosomal-associated protein 25
Authors:Stein, A., Weber, G., Wahl, M.C., Jahn, R.
Deposit date:2009-05-07
Release date:2009-07-14
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Helical extension of the neuronal SNARE complex into the membrane
Nature, 460, 2009
3IPD
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HELICAL EXTENSION OF THE NEURONAL SNARE COMPLEX INTO THE MEMBRANE, SPACEGROUP I 21 21 21
Descriptor:Vesicle-associated membrane protein 2, Syntaxin-1A, Synaptosomal-associated protein 25
Authors:Stein, A., Weber, G., Wahl, M.C., Jahn, R.
Deposit date:2009-08-17
Release date:2009-09-01
Method:X-RAY DIFFRACTION (4.8 Å)
Cite:Helical extension of the neuronal SNARE complex into the membrane
Nature, 460, 2009
3J96
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STRUCTURE OF 20S SUPERCOMPLEX DETERMINED BY SINGLE PARTICLE CRYOELECTRON MICROSCOPY (STATE I)
Descriptor:Vesicle-fusing ATPase (E.C.3.6.4.6), Alpha-soluble NSF attachment protein, Vesicle-associated membrane protein 2, Syntaxin-1A, Synaptosomal-associated protein 25
Authors:Zhao, M., Wu, S., Cheng, Y., Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Modification date:2015-02-11
Method:ELECTRON MICROSCOPY (7.601 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J97
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STRUCTURE OF 20S SUPERCOMPLEX DETERMINED BY SINGLE PARTICLE CRYOELECTRON MICROSCOPY (STATE II)
Descriptor:Vesicle-fusing ATPase (E.C.3.6.4.6), Alpha-soluble NSF attachment protein, Vesicle-associated membrane protein 2, Syntaxin-1A, Synaptosomal-associated protein 25
Authors:Zhao, M., Wu, S., Cheng, Y., Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Modification date:2015-02-11
Method:ELECTRON MICROSCOPY (7.804 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J98
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STRUCTURE OF 20S SUPERCOMPLEX DETERMINED BY SINGLE PARTICLE CRYOELECTRON MICROSCOPY (STATE IIIA)
Descriptor:Vesicle-fusing ATPase (E.C.3.6.4.6), Alpha-soluble NSF attachment protein, Vesicle-associated membrane protein 2, Syntaxin-1A, Synaptosomal-associated protein 25
Authors:Zhao, M., Wu, S., Cheng, Y., Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Modification date:2015-02-11
Method:ELECTRON MICROSCOPY (8.405 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J99
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STRUCTURE OF 20S SUPERCOMPLEX DETERMINED BY SINGLE PARTICLE CRYOELECTRON MICROSCOPY (STATE IIIB)
Descriptor:Vesicle-fusing ATPase (E.C.3.6.4.6), Alpha-soluble NSF attachment protein, Vesicle-associated membrane protein 2, Syntaxin-1A, Synaptosomal-associated protein 25
Authors:Zhao, M., Wu, S., Cheng, Y., Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Modification date:2015-02-11
Method:ELECTRON MICROSCOPY (8.201 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3RK2
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TRUNCATED SNARE COMPLEX
Descriptor:Vesicle-associated membrane protein 2, Syntaxin-1A, Synaptosomal-associated protein 25
Authors:Kuemmel, D., Reinisch, K.M.
Deposit date:2011-04-17
Release date:2011-07-27
Modification date:2011-08-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Complexin cross-links prefusion SNAREs into a zigzag array.
Nat.Struct.Mol.Biol., 18, 2011
3RK3
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TRUNCATED SNARE COMPLEX WITH COMPLEXIN
Descriptor:Vamp2, Syntaxin 1a, SNAP25, Complexin-1
Authors:Kuemmel, D., Reinisch, K.M.
Deposit date:2011-04-17
Release date:2011-07-27
Modification date:2011-08-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Complexin cross-links prefusion SNAREs into a zigzag array.
Nat.Struct.Mol.Biol., 18, 2011
3RL0
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TRUNCATED SNARE COMPLEX WITH COMPLEXIN (P1)
Descriptor:Vesicle-associated membrane protein 2, Syntaxin-1A, Synaptosomal-associated protein 25, Complexin-1
Authors:Kuemmel, D., Reinisch, K.M.
Deposit date:2011-04-19
Release date:2011-07-27
Modification date:2011-08-24
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Complexin cross-links prefusion SNAREs into a zigzag array.
Nat.Struct.Mol.Biol., 18, 2011
4JEH
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CRYSTAL STRUCTURE OF MUNC18A AND SYNTAXIN1 LACKING N-PEPTIDE COMPLEX
Descriptor:Syntaxin-binding protein 1, Syntaxin-1A
Authors:Colbert, K.N., Hattendorf, D.A., Weiss, T.M., Burkhardt, P., Fasshauer, D., Weis, W.I.
Deposit date:2013-02-27
Release date:2013-07-17
Modification date:2013-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation.
Proc.Natl.Acad.Sci.USA, 110, 2013
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