1KQ6
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2WWE
| Crystal structure of the phox homology domain of human phosphoinositide-3-kinase-C2-gamma | Descriptor: | PHOSPHOINOSITIDE-3-KINASE, CLASS 2, GAMMA POLYPEPTIDE | Authors: | Roos, A.K, Tresaugues, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotyenova, T, Kotzch, A, Kraulis, P, Markova, N, Moche, M, Nielsen, T.K, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Van Der Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | Deposit date: | 2009-10-22 | Release date: | 2009-11-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Crystal Structure of the Phox Homology Domain of Human Phosphoinositide-3-Kinase-C2-Gamma To be Published
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3HPC
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2V6V
| The structure of the Bem1p PX domain | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BUD EMERGENCE PROTEIN 1 | Authors: | Stahelin, R.V, Karathanassis, D, Murray, D, Williams, R.L, Cho, W. | Deposit date: | 2007-07-21 | Release date: | 2007-07-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural and Membrane Binding Analysis of the Phox Homology Domain of Bem1P: Basis of Phosphatidylinositol 4-Phosphate Specificity. J.Biol.Chem., 282, 2007
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4IKD
| Crystal structure of SNX11 PX domain | Descriptor: | CHLORIDE ION, SODIUM ION, Sorting nexin-11 | Authors: | Xu, J, Xu, T, Liu, J. | Deposit date: | 2012-12-26 | Release date: | 2013-04-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of Sorting Nexin 11 (SNX11) Reveals a Novel Extended PX Domain (PXe Domain) Critical for the Inhibition of Sorting Nexin 10 (SNX10) Induced Vacuolation to be published
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1XTE
| crystal structure of CISK-PX domain | Descriptor: | Serine/threonine-protein kinase Sgk3 | Authors: | Xing, Y, Liu, D, Zhang, R, Joachimiak, A, Songyang, Z, Xu, W. | Deposit date: | 2004-10-21 | Release date: | 2004-11-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis of membrane targeting by the Phox homology domain of cytokine-independent survival kinase (CISK-PX) J.Biol.Chem., 279, 2004
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5XDZ
| Crystal structure of zebrafish SNX25 PX domain | Descriptor: | CHLORIDE ION, Cellular trafficking protein, SODIUM ION | Authors: | Su, K, Zhang, Y, Xu, J, Liu, J. | Deposit date: | 2017-03-30 | Release date: | 2017-06-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the PX domain of SNX25 reveals a novel phospholipid recognition model by dimerization in the PX domain FEBS Lett., 591, 2017
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3IQ2
| Human sorting nexin 7, phox homology (PX) domain | Descriptor: | GLYCEROL, SULFATE ION, Sorting nexin-7 | Authors: | Karlberg, T, Wisniewska, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Kotzsch, A, Kraulis, P, Nielsen, T.K, Moche, M, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Schutz, P, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-08-19 | Release date: | 2009-09-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Human Sorting Nexin 7, Phox Homology (Px) Domain To be Published
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1H6H
| Structure of the PX domain from p40phox bound to phosphatidylinositol 3-phosphate | Descriptor: | 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, GLYCEROL, NEUTROPHIL CYTOSOL FACTOR 4 | Authors: | Karathanassis, D, Bravo, J, Pacold, M, Perisic, O, Williams, R.L. | Deposit date: | 2001-06-15 | Release date: | 2001-11-01 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Crystal Structure of the Px Domain from P40Phox Bound to Phosphatidylinositol 3-Phosphate Mol.Cell, 8, 2001
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4HAS
| Crystal structure of PX domain of human sorting nexin SNX27 | Descriptor: | 1,2-ETHANEDIOL, CITRIC ACID, Sorting nexin-27 | Authors: | Froese, D.S, Krojer, T, Strain-Damerell, C, Allerston, C, Kiyani, W, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Bountra, C, Edwards, A, Yue, W.W, Structural Genomics Consortium (SGC) | Deposit date: | 2012-09-27 | Release date: | 2013-04-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Crystal structure of PX domain of human sorting nexin SNX27 To be Published
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4AZ9
| Crystal structure of phox homology domain of human sorting nexin 24 | Descriptor: | 1,2-ETHANEDIOL, SORTING NEXIN-24 | Authors: | Oberholzer, A.E, Kiyani, W, Krojer, T, Shrestha, L, von Delft, F, Froese, D.S, Chaikuad, A, Raynor, J, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W. | Deposit date: | 2012-06-24 | Release date: | 2012-10-10 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structure of Phox Homology Domain of Human Sorting Nexin 24 To be Published
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5ZN9
| Crystal structure of PX domain | Descriptor: | SULFATE ION, Sorting nexin-27 | Authors: | Li, Y, Zhu, Z, Li, F, Liao, S, Xu, C. | Deposit date: | 2018-04-08 | Release date: | 2019-04-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.776 Å) | Cite: | Crystal structure of PX domain To Be Published
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4IKB
| Crystal structure of SNX11 PX domain | Descriptor: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CHLORIDE ION, SODIUM ION, ... | Authors: | Xu, J, Xu, T, Liu, J. | Deposit date: | 2012-12-26 | Release date: | 2013-04-24 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structure of Sorting Nexin 11 (SNX11) Reveals a Novel Extended PX Domain (PXe Domain) Critical for the Inhibition of Sorting Nexin 10 (SNX10) Induced Vacuolation to be published
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3LUI
| Crystal structure of the SNX17 PX domain with bound sulphate | Descriptor: | SULFATE ION, Sorting nexin-17 | Authors: | Ghai, R, Collins, B.M. | Deposit date: | 2010-02-17 | Release date: | 2010-03-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases Proc.Natl.Acad.Sci.USA, 2011
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2AR5
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4P2I
| Crystal structure of the mouse SNX19 PX domain | Descriptor: | MKIAA0254 protein | Authors: | Collins, B.M. | Deposit date: | 2014-03-04 | Release date: | 2014-09-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling. J.Biol.Chem., 289, 2014
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5WY2
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5TGI
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1O7K
| human p47 PX domain complex with sulphates | Descriptor: | NEUTROPHIL CYTOSOL FACTOR 1, SULFATE ION | Authors: | Karathanassis, D, Bravo, J, Perisic, O, Pacold, C.M, Williams, R.L. | Deposit date: | 2002-11-07 | Release date: | 2002-11-20 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Binding of the Px Domain of P47Phox to Phosphatidylinositol 3.4-Bisphosphate and Phosphatidic Acid is Masked by an Intramolecular Interaction Embo J., 21, 2002
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6KOK
| Crystal Structure of SNX11/SNX10-PXe Chimera | Descriptor: | CHLORIDE ION, SODIUM ION, Sorting nexin-11,Uncharacterized protein SNX10 | Authors: | Xu, T, Liu, J. | Deposit date: | 2019-08-11 | Release date: | 2020-07-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular Basis for PI(3,5)P2Recognition by SNX11, a Protein Involved in Lysosomal Degradation and Endosome Homeostasis Regulation. J.Mol.Biol., 432, 2020
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6EDX
| Crystal Structure of SGK3 PX domain | Descriptor: | GLYCEROL, Serine/threonine-protein kinase Sgk3 | Authors: | Chandra, M, Collins, B.M. | Deposit date: | 2018-08-12 | Release date: | 2018-09-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.009 Å) | Cite: | Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities. Nat Commun, 10, 2019
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7X4O
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1OCS
| Crystal structure of the yeast PX-doamin protein Grd19p (sorting nexin3) complexed to phosphatidylinosytol-3-phosphate. | Descriptor: | GLYCEROL, SORTING NEXIN GRD19 | Authors: | Zhou, C.Z, Li De La Sierra-Gallay, I, Cheruel, S, Collinet, B, Minard, P, Blondeau, K, Henkes, G, Aufrere, R, Leulliot, N, Graille, M, Sorel, I, Savarin, P, De La Torre, F, Poupon, A, Janin, J, Van Tilbeurgh, H. | Deposit date: | 2003-02-10 | Release date: | 2003-12-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Crystal Structure of the Yeast Phox Homology (Px) Protein Grd19P (Sorting Nexin 3) Complexed to Phosphatidylinositol-3-Phosphate J.Biol.Chem., 278, 2003
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6N5X
| Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1) | Descriptor: | GLYCEROL, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), Sorting nexin-5,Cation-independent mannose-6-phosphate receptor | Authors: | Collins, B, Paul, B, Weeratunga, S. | Deposit date: | 2018-11-22 | Release date: | 2019-09-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.051 Å) | Cite: | Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins. Nat.Cell Biol., 21, 2019
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3DYT
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