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1KQ6
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BU of 1kq6 by Molmil
p47phox PX domain
Descriptor: GLYCEROL, SULFATE ION, neutrophil cytosol factor 1
Authors:Wahl, M, Delbrueck, H, Oschkinat, H, Heinemann, U.
Deposit date:2002-01-04
Release date:2003-11-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:p47phox PX domain
To be Published
2WWE
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BU of 2wwe by Molmil
Crystal structure of the phox homology domain of human phosphoinositide-3-kinase-C2-gamma
Descriptor: PHOSPHOINOSITIDE-3-KINASE, CLASS 2, GAMMA POLYPEPTIDE
Authors:Roos, A.K, Tresaugues, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotyenova, T, Kotzch, A, Kraulis, P, Markova, N, Moche, M, Nielsen, T.K, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Van Der Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC)
Deposit date:2009-10-22
Release date:2009-11-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal Structure of the Phox Homology Domain of Human Phosphoinositide-3-Kinase-C2-Gamma
To be Published
3HPC
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BU of 3hpc by Molmil
Crystal structure of SNX5-PX domain in P21 space group
Descriptor: CHLORIDE ION, Snx5 protein
Authors:Koharudin, L.M.I, Furey, W, Gronenborn, A.M.
Deposit date:2009-06-03
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:The Phox domain of sorting nexin 5 lacks ptdins(3)p specificity and preferentially binds to ptdins(4,5)P2
To be Published
2V6V
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BU of 2v6v by Molmil
The structure of the Bem1p PX domain
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BUD EMERGENCE PROTEIN 1
Authors:Stahelin, R.V, Karathanassis, D, Murray, D, Williams, R.L, Cho, W.
Deposit date:2007-07-21
Release date:2007-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Membrane Binding Analysis of the Phox Homology Domain of Bem1P: Basis of Phosphatidylinositol 4-Phosphate Specificity.
J.Biol.Chem., 282, 2007
4IKD
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BU of 4ikd by Molmil
Crystal structure of SNX11 PX domain
Descriptor: CHLORIDE ION, SODIUM ION, Sorting nexin-11
Authors:Xu, J, Xu, T, Liu, J.
Deposit date:2012-12-26
Release date:2013-04-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of Sorting Nexin 11 (SNX11) Reveals a Novel Extended PX Domain (PXe Domain) Critical for the Inhibition of Sorting Nexin 10 (SNX10) Induced Vacuolation
to be published
1XTE
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BU of 1xte by Molmil
crystal structure of CISK-PX domain
Descriptor: Serine/threonine-protein kinase Sgk3
Authors:Xing, Y, Liu, D, Zhang, R, Joachimiak, A, Songyang, Z, Xu, W.
Deposit date:2004-10-21
Release date:2004-11-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of membrane targeting by the Phox homology domain of cytokine-independent survival kinase (CISK-PX)
J.Biol.Chem., 279, 2004
5XDZ
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BU of 5xdz by Molmil
Crystal structure of zebrafish SNX25 PX domain
Descriptor: CHLORIDE ION, Cellular trafficking protein, SODIUM ION
Authors:Su, K, Zhang, Y, Xu, J, Liu, J.
Deposit date:2017-03-30
Release date:2017-06-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the PX domain of SNX25 reveals a novel phospholipid recognition model by dimerization in the PX domain
FEBS Lett., 591, 2017
3IQ2
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Human sorting nexin 7, phox homology (PX) domain
Descriptor: GLYCEROL, SULFATE ION, Sorting nexin-7
Authors:Karlberg, T, Wisniewska, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Kotzsch, A, Kraulis, P, Nielsen, T.K, Moche, M, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Schutz, P, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC)
Deposit date:2009-08-19
Release date:2009-09-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Human Sorting Nexin 7, Phox Homology (Px) Domain
To be Published
1H6H
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BU of 1h6h by Molmil
Structure of the PX domain from p40phox bound to phosphatidylinositol 3-phosphate
Descriptor: 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, GLYCEROL, NEUTROPHIL CYTOSOL FACTOR 4
Authors:Karathanassis, D, Bravo, J, Pacold, M, Perisic, O, Williams, R.L.
Deposit date:2001-06-15
Release date:2001-11-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Crystal Structure of the Px Domain from P40Phox Bound to Phosphatidylinositol 3-Phosphate
Mol.Cell, 8, 2001
4HAS
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BU of 4has by Molmil
Crystal structure of PX domain of human sorting nexin SNX27
Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, Sorting nexin-27
Authors:Froese, D.S, Krojer, T, Strain-Damerell, C, Allerston, C, Kiyani, W, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Bountra, C, Edwards, A, Yue, W.W, Structural Genomics Consortium (SGC)
Deposit date:2012-09-27
Release date:2013-04-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of PX domain of human sorting nexin SNX27
To be Published
4AZ9
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BU of 4az9 by Molmil
Crystal structure of phox homology domain of human sorting nexin 24
Descriptor: 1,2-ETHANEDIOL, SORTING NEXIN-24
Authors:Oberholzer, A.E, Kiyani, W, Krojer, T, Shrestha, L, von Delft, F, Froese, D.S, Chaikuad, A, Raynor, J, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W.
Deposit date:2012-06-24
Release date:2012-10-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure of Phox Homology Domain of Human Sorting Nexin 24
To be Published
5ZN9
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BU of 5zn9 by Molmil
Crystal structure of PX domain
Descriptor: SULFATE ION, Sorting nexin-27
Authors:Li, Y, Zhu, Z, Li, F, Liao, S, Xu, C.
Deposit date:2018-04-08
Release date:2019-04-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.776 Å)
Cite:Crystal structure of PX domain
To Be Published
4IKB
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BU of 4ikb by Molmil
Crystal structure of SNX11 PX domain
Descriptor: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CHLORIDE ION, SODIUM ION, ...
Authors:Xu, J, Xu, T, Liu, J.
Deposit date:2012-12-26
Release date:2013-04-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of Sorting Nexin 11 (SNX11) Reveals a Novel Extended PX Domain (PXe Domain) Critical for the Inhibition of Sorting Nexin 10 (SNX10) Induced Vacuolation
to be published
3LUI
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BU of 3lui by Molmil
Crystal structure of the SNX17 PX domain with bound sulphate
Descriptor: SULFATE ION, Sorting nexin-17
Authors:Ghai, R, Collins, B.M.
Deposit date:2010-02-17
Release date:2010-03-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases
Proc.Natl.Acad.Sci.USA, 2011
2AR5
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BU of 2ar5 by Molmil
Crystal structure of the mammalian C2alpha-PI3 Kinase PX-domain
Descriptor: GLYCEROL, Phosphoinositide 3-kinase
Authors:Parkinson, G.N, Vines, D, Driscoll, P.C, Djordjevic, S.
Deposit date:2005-08-19
Release date:2006-10-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ligand-binding specificity of PI3Kinase C2alpha PX domain.
To be Published
4P2I
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BU of 4p2i by Molmil
Crystal structure of the mouse SNX19 PX domain
Descriptor: MKIAA0254 protein
Authors:Collins, B.M.
Deposit date:2014-03-04
Release date:2014-09-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
5WY2
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BU of 5wy2 by Molmil
Human Snx5 PX domain in complex with Chlamydia IncE C terminus
Descriptor: IncE, Sorting nexin-5
Authors:Sun, Q, Yong, X, Jia, D.
Deposit date:2017-01-10
Release date:2017-11-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional insights into sorting nexin 5/6 interaction with bacterial effector IncE.
Signal Transduct Target Ther, 2, 2017
5TGI
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BU of 5tgi by Molmil
Structure of the SNX5 PX domain in complex with chlamydial protein IncE in space group P212121
Descriptor: IncE, Sorting nexin-5
Authors:Collins, B, Paul, B.
Deposit date:2016-09-28
Release date:2017-06-28
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure of the SNX5 PX domain in complex with chlamydial protein IncE
To Be Published
1O7K
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BU of 1o7k by Molmil
human p47 PX domain complex with sulphates
Descriptor: NEUTROPHIL CYTOSOL FACTOR 1, SULFATE ION
Authors:Karathanassis, D, Bravo, J, Perisic, O, Pacold, C.M, Williams, R.L.
Deposit date:2002-11-07
Release date:2002-11-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of the Px Domain of P47Phox to Phosphatidylinositol 3.4-Bisphosphate and Phosphatidic Acid is Masked by an Intramolecular Interaction
Embo J., 21, 2002
6KOK
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BU of 6kok by Molmil
Crystal Structure of SNX11/SNX10-PXe Chimera
Descriptor: CHLORIDE ION, SODIUM ION, Sorting nexin-11,Uncharacterized protein SNX10
Authors:Xu, T, Liu, J.
Deposit date:2019-08-11
Release date:2020-07-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Basis for PI(3,5)P2Recognition by SNX11, a Protein Involved in Lysosomal Degradation and Endosome Homeostasis Regulation.
J.Mol.Biol., 432, 2020
6EDX
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BU of 6edx by Molmil
Crystal Structure of SGK3 PX domain
Descriptor: GLYCEROL, Serine/threonine-protein kinase Sgk3
Authors:Chandra, M, Collins, B.M.
Deposit date:2018-08-12
Release date:2018-09-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.009 Å)
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
7X4O
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BU of 7x4o by Molmil
Crystal structure of Vps17p PX from S. cerevisiae (Space)
Descriptor: SULFATE ION, Vacuolar protein sorting-associated protein 17
Authors:Maita, N, Kohda, D, Obita, T.
Deposit date:2022-03-03
Release date:2022-05-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal structure of the PX domain of Vps17p from Saccharomyces cerevisiae.
Acta Crystallogr.,Sect.F, 78, 2022
1OCS
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BU of 1ocs by Molmil
Crystal structure of the yeast PX-doamin protein Grd19p (sorting nexin3) complexed to phosphatidylinosytol-3-phosphate.
Descriptor: GLYCEROL, SORTING NEXIN GRD19
Authors:Zhou, C.Z, Li De La Sierra-Gallay, I, Cheruel, S, Collinet, B, Minard, P, Blondeau, K, Henkes, G, Aufrere, R, Leulliot, N, Graille, M, Sorel, I, Savarin, P, De La Torre, F, Poupon, A, Janin, J, Van Tilbeurgh, H.
Deposit date:2003-02-10
Release date:2003-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal Structure of the Yeast Phox Homology (Px) Protein Grd19P (Sorting Nexin 3) Complexed to Phosphatidylinositol-3-Phosphate
J.Biol.Chem., 278, 2003
6N5X
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BU of 6n5x by Molmil
Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1)
Descriptor: GLYCEROL, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), Sorting nexin-5,Cation-independent mannose-6-phosphate receptor
Authors:Collins, B, Paul, B, Weeratunga, S.
Deposit date:2018-11-22
Release date:2019-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
3DYT
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BU of 3dyt by Molmil
Crystal structure of Snx9PX-BAR (230-595), C2221
Descriptor: SULFATE ION, Sorting nexin-9
Authors:Wang, Q, Kaan, H.Y.K, Sondermann, H.
Deposit date:2008-07-28
Release date:2008-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structure and plasticity of endophilin and sorting nexin 9.
Structure, 16, 2008

 

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