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8WEJ
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BU of 8wej by Molmil
Structure of human phagocyte NADPH oxidase in the activated state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, 7D5 Fab light chain, ...
Authors:Chen, L, Liu, X.
Deposit date:2023-09-18
Release date:2024-01-24
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Structure of human phagocyte NADPH oxidase in the activated state.
Nature, 627, 2024
8HQL
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BU of 8hql by Molmil
Crystal structure of mouse SNX25 PX domain
Descriptor: ACETIC ACID, CHLORIDE ION, GLYCEROL, ...
Authors:Yu, Z, Xu, J, Liu, J.
Deposit date:2022-12-13
Release date:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of mouse SNX25 PX domain
To Be Published
8ESF
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BU of 8esf by Molmil
Crystal structure of human Nischarin PX and LRR domains with engineered mutations
Descriptor: IMIDAZOLE, Nischarin
Authors:Eldershaw, D.E, Collins, B.M.
Deposit date:2022-10-13
Release date:2023-10-25
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Crystal structure of human Nischarin PX and LRR domains with engineered mutations
To Be Published
8AFZ
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BU of 8afz by Molmil
Architecture of the ESCPE-1 membrane coat
Descriptor: Cation-independent mannose-6-phosphate receptor, Sorting nexin-1, Sorting nexin-5
Authors:Lopez-Robles, C, Scaramuzza, S, Astorga-Simon, E, Ishida, M, Williamsom, C.D, Banos-Mateos, S, Gil-Carton, D, Romero, M, Vidaurrazaga, A, Fernandez-Recio, J, Rojas, A.L, Bonifacino, J.S, Castano-Diez, D, Hierro, A.
Deposit date:2022-07-18
Release date:2023-06-21
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Architecture of the ESCPE-1 membrane coat.
Nat.Struct.Mol.Biol., 30, 2023
7X4O
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BU of 7x4o by Molmil
Crystal structure of Vps17p PX from S. cerevisiae (Space)
Descriptor: SULFATE ION, Vacuolar protein sorting-associated protein 17
Authors:Maita, N, Kohda, D, Obita, T.
Deposit date:2022-03-03
Release date:2022-05-18
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal structure of the PX domain of Vps17p from Saccharomyces cerevisiae.
Acta Crystallogr.,Sect.F, 78, 2022
7BI2
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BU of 7bi2 by Molmil
PI3KC2aDeltaN and DeltaC-C2
Descriptor: 1,2-ETHANEDIOL, 9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2(1H)-one, IODIDE ION, ...
Authors:Lo, W.T, Roske, Y, Daumke, O, Haucke, V.
Deposit date:2021-01-12
Release date:2022-03-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural basis of phosphatidylinositol 3-kinase C2 alpha function.
Nat.Struct.Mol.Biol., 29, 2022
7D6D
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BU of 7d6d by Molmil
Structural insights into membrane remodeling by SNX1
Descriptor: Sorting nexin-1
Authors:Zhang, Y, Pang, X, Sun, F.
Deposit date:2020-09-30
Release date:2021-03-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structural insights into membrane remodeling by SNX1.
Proc.Natl.Acad.Sci.USA, 118, 2021
7D6E
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BU of 7d6e by Molmil
Structural insights into membrane remodeling by SNX1
Descriptor: Sorting nexin-1
Authors:Zhang, Y, Pang, X, Sun, F.
Deposit date:2020-09-30
Release date:2021-03-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Structural insights into membrane remodeling by SNX1.
Proc.Natl.Acad.Sci.USA, 118, 2021
7BLO
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BU of 7blo by Molmil
VPS26 dimer region of metazoan membrane-assembled retromer:SNX3 complex modelled with human proteins
Descriptor: 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, C-term (residues 493-54) of Wls (fitted sequence corresponds to hDMT1-II), Sorting nexin-3, ...
Authors:Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J.
Deposit date:2021-01-18
Release date:2021-03-03
Last modified:2021-04-07
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
7BLQ
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BU of 7blq by Molmil
Vps26 dimer region of the fungal membrane-assembled retromer:Grd19 complex.
Descriptor: 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, Sorting nexin-3, The C-terminal portion of Kex2 cargo, ...
Authors:Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J.
Deposit date:2021-01-18
Release date:2021-03-03
Last modified:2021-04-07
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
6KOJ
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BU of 6koj by Molmil
Crystal structure of SNX11-PXe domain in complex with PI(3,5)P2
Descriptor: Sorting nexin-11, [(2~{R})-2-butanoyloxy-3-[oxidanyl-[(2~{R},3~{R},5~{S},6~{R})-2,4,6-tris(oxidanyl)-3,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] butanoate
Authors:Xu, T, Liu, J.
Deposit date:2019-08-11
Release date:2020-07-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Molecular Basis for PI(3,5)P2Recognition by SNX11, a Protein Involved in Lysosomal Degradation and Endosome Homeostasis Regulation.
J.Mol.Biol., 432, 2020
6KOK
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BU of 6kok by Molmil
Crystal Structure of SNX11/SNX10-PXe Chimera
Descriptor: CHLORIDE ION, SODIUM ION, Sorting nexin-11,Uncharacterized protein SNX10
Authors:Xu, T, Liu, J.
Deposit date:2019-08-11
Release date:2020-07-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Basis for PI(3,5)P2Recognition by SNX11, a Protein Involved in Lysosomal Degradation and Endosome Homeostasis Regulation.
J.Mol.Biol., 432, 2020
6KOI
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BU of 6koi by Molmil
Crystal structure of SNX11-PXe domain in dimer form.
Descriptor: Sorting nexin-11
Authors:Xu, T, Xu, J, Liu, J.
Deposit date:2019-08-11
Release date:2020-07-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular Basis for PI(3,5)P2Recognition by SNX11, a Protein Involved in Lysosomal Degradation and Endosome Homeostasis Regulation.
J.Mol.Biol., 432, 2020
6Q0X
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BU of 6q0x by Molmil
The cryo-EM structure of the SNX-BAR Mvp1 tetramer
Descriptor: Sorting nexin MVP1
Authors:Sun, D, Ford, M.G.J, Zhang, P.
Deposit date:2019-08-02
Release date:2020-04-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The cryo-EM structure of the SNX-BAR Mvp1 tetramer.
Nat Commun, 11, 2020
6N5X
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BU of 6n5x by Molmil
Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1)
Descriptor: GLYCEROL, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), Sorting nexin-5,Cation-independent mannose-6-phosphate receptor
Authors:Collins, B, Paul, B, Weeratunga, S.
Deposit date:2018-11-22
Release date:2019-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
6N5Z
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BU of 6n5z by Molmil
Crystal structure of the SNX5 PX domain in complex with the Sema4C
Descriptor: CHLORIDE ION, Sorting nexin-5,Semaphorin-4C
Authors:Collins, B, Paul, B, Weeratunga, S.
Deposit date:2018-11-22
Release date:2019-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
6N5Y
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BU of 6n5y by Molmil
Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1)
Descriptor: Sorting nexin-5,Cation-independent mannose-6-phosphate receptor
Authors:Collins, B, Paul, B, Weeratunga, S.
Deposit date:2018-11-22
Release date:2019-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
5ZN9
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BU of 5zn9 by Molmil
Crystal structure of PX domain
Descriptor: SULFATE ION, Sorting nexin-27
Authors:Li, Y, Zhu, Z, Li, F, Liao, S, Xu, C.
Deposit date:2018-04-08
Release date:2019-04-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.776 Å)
Cite:Crystal structure of PX domain
To Be Published
6BUB
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BU of 6bub by Molmil
Crystal structure of the PI3KC2alpha PX domain in space group P432
Descriptor: GLYCEROL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, SULFATE ION
Authors:Chen, K.-E, Collins, B.M.
Deposit date:2017-12-09
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
6H7W
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BU of 6h7w by Molmil
Model of retromer-Vps5 complex assembled on membrane.
Descriptor: Putative vacuolar protein sorting-associated protein, Vacuolar protein sorting-associated protein 26-like protein, Vacuolar protein sorting-associated protein 29, ...
Authors:Kovtun, O, Leneva, N, Ariotti, N, Rohan, T.S, Owen, D.J, Briggs, J.A.G, Collins, B.M.
Deposit date:2018-07-31
Release date:2018-09-26
Last modified:2018-10-10
Method:ELECTRON MICROSCOPY (11.4 Å)
Cite:Structure of the membrane-assembled retromer coat determined by cryo-electron tomography.
Nature, 561, 2018
6E8R
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BU of 6e8r by Molmil
Structure of the SNX32 PX domain in complex with Chlamydial protein IncE in space group I121
Descriptor: IncE, Sorting nexin-32
Authors:Paul, B, Collins, B.
Deposit date:2018-07-31
Release date:2018-09-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.268 Å)
Cite:Crystal structure of the SNX32 PX domain in complex with the Chlamydia trachomatis inclusion protein IncE
To be Published
6MBI
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BU of 6mbi by Molmil
Crystal Structure of SNX15 PX domain in domain swapped conformation form 2
Descriptor: Sorting nexin-15
Authors:Chandra, M, Collins, B.M.
Deposit date:2018-08-29
Release date:2018-09-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.834 Å)
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
6EDX
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BU of 6edx by Molmil
Crystal Structure of SGK3 PX domain
Descriptor: GLYCEROL, Serine/threonine-protein kinase Sgk3
Authors:Chandra, M, Collins, B.M.
Deposit date:2018-08-12
Release date:2018-09-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.009 Å)
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
6EE0
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BU of 6ee0 by Molmil
Crystal Structure of SNX23 PX domain
Descriptor: Kinesin-like protein KIF16B
Authors:Chandra, M, Collins, B.M.
Deposit date:2018-08-12
Release date:2018-08-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.518 Å)
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
6ECM
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BU of 6ecm by Molmil
Crystal Structure of SNX15 PX domain in domain swapped conformation
Descriptor: SULFATE ION, Sorting nexin-15
Authors:Chandra, M, Collins, B.M.
Deposit date:2018-08-08
Release date:2018-08-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.353 Å)
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019

 

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