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1I9S
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1i9s
CRYSTAL STRUCTURE OF THE RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME
Descriptor:MRNA CAPPING ENZYME (E.C.3.1.3.33)
Authors:Changela, A., Ho, C.K., Martins, A., Shuman, S., Mondragon, A.
Deposit date:2001-03-20
Release date:2001-05-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
1I9T
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1i9t
CRYSTAL STRUCTURE OF THE OXIDIZED RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME
Descriptor:MRNA CAPPING ENZYME (E.C.3.1.3.33)
Authors:Changela, A., Ho, C.K., Martins, A., Shuman, S., Mondragon, A.
Deposit date:2001-03-20
Release date:2001-05-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
1J4X
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1j4x
HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE C124S MUTANT-PEPTIDE COMPLEX
Descriptor:DUAL SPECIFICITY PROTEIN PHOSPHATASE 3, DDE(AHP)(TPO)G(PTR)VATR
Authors:Schumacher, M.A., Todd, J.L., Tanner, K.G., Denu, J.M.
Deposit date:2001-12-13
Release date:2001-12-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for the recognition of a bisphosphorylated MAP kinase peptide by human VHR protein Phosphatase.
Biochemistry, 41, 2002
1M3G
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1m3g
SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF MAPK PHOSPHATASE PAC-1: INSIGHTS INTO SUBSTRATE-INDUCED ENZYMATIC ACTIVATION
Descriptor:DUAL SPECIFICITY PROTEIN PHOSPHATASE 2 (E.C.3.1.3.48)(E.C.3.1.3.16)
Authors:Farooq, A., Zhou, M.-M.
Deposit date:2002-06-27
Release date:2003-06-27
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution Structure of the MAPK Phosphatase PAC-1 Catalytic Domain Insights into Substrate-Induced Enzymatic Activation of MKP
Structure, 11, 2003
1MKP
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1mkp
CRYSTAL STRUCTURE OF PYST1 (MKP3)
Descriptor:PYST1
Authors:Stewart, A.E., Dowd, S., Keyse, S., Mcdonald, N.Q.
Deposit date:1998-07-11
Release date:1999-07-22
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation.
Nat.Struct.Biol., 6, 1999
1VHR
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1vhr
HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE
Descriptor:HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE VHR, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Yuvaniyama, J., Denu, J.M., Dixon, J.E., Saper, M.A.
Deposit date:1996-02-20
Release date:1996-06-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the dual specificity protein phosphatase VHR.
Science, 272, 1996
1WRM
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1wrm
CRYSTAL STRUCTURE OF JSP-1
Descriptor:dual specificity phosphatase 22(E.C.3.1.3.48)
Authors:Yokota, T., Kashima, A., Kato, R., Sugio, S.
Deposit date:2004-10-22
Release date:2005-10-22
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of human dual specificity phosphatase, JNK stimulatory phosphatase-1, at 1.5 A resolution
Proteins, 66, 2006
1X24
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1x24
PRL-1 (PTP4A)
Descriptor:protein tyrosine phosphatase 4a1
Authors:Zhang, Z.Y., Sun, J.P., Liu, S., Wang, W.Q., Yang, H.
Deposit date:2005-04-20
Release date:2005-10-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and Biochemical Properties of PRL-1, a Phosphatase Implicated in Cell Growth, Differentiation, and Tumor Invasion(,)
Biochemistry, 44, 2005
1YN9
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1yn9
CRYSTAL STRUCTURE OF BACULOVIRUS RNA 5'-PHOSPHATASE COMPLEXED WITH PHOSPHATE
Descriptor:Tyrosine-protein phosphatase (E.C.3.1.3.48)
Authors:Changela, A., Martins, A., Shuman, S., Mondragon, A.
Deposit date:2005-01-24
Release date:2005-02-22
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of baculovirus RNA triphosphatase complexed with phosphate
J.Biol.Chem., 280, 2005
1YZ4
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1yz4
CRYSTAL STRUCTURE OF DUSP15
Descriptor:dual specificity phosphatase-like 15 isoform a(E.C.3.1.3.48)
Authors:Kim, S.J., Ryu, S.E., Jeong, D.G., Yoon, T.S., Kim, J.H., Cho, Y.H., Jeong, S.K., Lee, J.W., Son, J.H.
Deposit date:2005-02-28
Release date:2005-11-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the catalytic domain of human VHY, a dual-specificity protein phosphatase
Proteins, 61, 2005
1ZCK
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1zck
NATIVE STRUCTURE PRL-1 (PTP4A1)
Descriptor:protein tyrosine phosphatase 4a1
Authors:Sun, J.P., Wang, W.Q., Yang, H., Liu, S., Liang, F., Fedorov, A.A., Almo, S.C., Zhang, Z.Y.
Deposit date:2005-04-12
Release date:2005-09-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Biochemical Properties of PRL-1, a Phosphatase Implicated in Cell Growth, Differentiation, and Tumor Invasion.
Biochemistry, 44, 2005
1ZCL
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1zcl
PRL-1 C104S MUTANT IN COMPLEX WITH SULFATE
Descriptor:protein tyrosine phosphatase 4a1
Authors:Sun, J.P., Wang, W.Q., Yang, H., Liu, S., Liang, F., Fedorov, A.A., Almo, S.C., Zhang, Z.Y.
Deposit date:2005-04-12
Release date:2005-09-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and Biochemical Properties of PRL-1, a Phosphatase Implicated in Cell Growth, Differentiation, and Tumor Invasion.
Biochemistry, 44, 2005
1ZZW
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1zzw
CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF HUMAN MAP KINASE PHOSPHATASE 5
Descriptor:Dual specificity protein phosphatase 10 (E.C.3.1.3.48, 3.1.3.16)
Authors:Jeong, D.G., Yoon, T.S., Kim, J.H., Shim, M.Y., Jeong, S.K., Son, J.H., Ryu, S.E., Kim, S.J.
Deposit date:2005-06-14
Release date:2006-07-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of the Catalytic Domain of Human MAP Kinase Phosphatase 5: Structural Insight into Constitutively Active Phosphatase.
J.Mol.Biol., 360, 2006
2C46
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2c46
CRYSTAL STRUCTURE OF THE HUMAN RNA GUANYLYLTRANSFERASE AND 5'- PHOSPHATASE
Descriptor:MRNA CAPPING ENZYME (E.C.2.7.7.50)
Authors:Debreczeni, J., Johansson, C., Longman, E., Gileadi, O., Savitskysmee, P., Smee, C., Bunkoczi, G., Ugochukwu, E., Von Delft, F., Sundstrom, M., Weigelt, J., Arrowsmith, C., Edwards, A., Knapp, S.
Deposit date:2005-10-15
Release date:2005-11-01
Modification date:2012-12-05
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of the Human RNA Guanylyltransferase and 5'-Phosphatase
To be Published
2E0T
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2e0t
CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF DUAL SPECIFICITY PHOSPHATASE 26, MS0830 FROM HOMO SAPIENS
Descriptor:Dual specificity phosphatase 26
Authors:Xie, Y., Kishishita, S., Murayama, K., Hori-Takemoto, C., Chen, L., Liu, Z.J., Wang, B.C., Shirozu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-10-13
Release date:2007-10-16
Modification date:2013-06-12
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:High-resolution crystal structure of the catalytic domain of human dual-specificity phosphatase 26.
Acta Crystallogr.,Sect.D, 69, 2013
2ESB
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2esb
CRYSTAL STRUCTURE OF HUMAN DUSP18
Descriptor:Dual specificity protein phosphatase 18 (E.C.3.1.3.48, 3.1.3.16)
Authors:Kim, S.J., Ryu, S.E., Jeong, D.G., Cho, Y.H., Yoon, T.S., Kim, J.H.
Deposit date:2005-10-25
Release date:2006-06-06
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of human DSP18, a member of the dual-specificity protein tyrosine phosphatase family.
Acta Crystallogr.,Sect.D, 62, 2006
2G6Z
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2g6z
CRYSTAL STRUCTURE OF HUMAN DUSP5
Descriptor:Dual specificity protein phosphatase 5 (E.C.3.1.3.48, 3.1.3.16)
Authors:Kim, S.J., Ryu, S.E.
Deposit date:2006-02-26
Release date:2007-01-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the catalytic domain of human DUSP5, a dual specificity MAP kinase protein phosphatase
Proteins, 66, 2007
2GWO
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2gwo
CRYSTAL STRUCTURE OF TMDP
Descriptor:Dual specificity protein phosphatase 13 (E.C.3.1.3.48, 3.1.3.16)
Authors:Kim, S.J., Ryu, S.E., Kim, J.H.
Deposit date:2006-05-05
Release date:2007-03-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of human TMDP, a testis-specific dual specificity protein phosphatase: implications for substrate specificity
Proteins, 66, 2007
2HCM
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2hcm
CRYSTAL STRUCTURE OF MOUSE PUTATIVE DUAL SPECIFICITY PHOSPHATASE COMPLEXED WITH ZINC TUNGSTATE, NEW YORK STRUCTURAL GENOMICS CONSORTIUM
Descriptor:Crystal structure, Putative dual specificity phosphatase
Authors:Patskovsky, Y., Almo, S.C., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-06-17
Release date:2006-08-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
2HXP
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2hxp
CRYSTAL STRUCTURE OF THE HUMAN PHOSPHATASE (DUSP9)
Descriptor:Dual specificity protein phosphatase 9 (E.C.3.1.3.48)
Authors:Madegowda, M., Eswaramoorthy, S., Burley, S.K., Swaminathan, S., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-08-03
Release date:2006-08-22
Modification date:2008-03-25
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
2IMG
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2img
CRYSTAL STRUCTURE OF DUAL SPECIFICITY PROTEIN PHOSPHATASE 23 FROM HOMO SAPIENS IN COMPLEX WITH LIGAND MALATE ION
Descriptor:Dual specificity protein phosphatase 23 (E.C.3.1.3.48, 3.1.3.16)
Authors:Agarwal, R., Burley, S.K., Swaminathan, S., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-10-04
Release date:2006-10-17
Modification date:2008-10-21
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structure of human dual specificity protein phosphatase 23, VHZ, enzyme-substrate/product complex.
J.Biol.Chem., 283, 2008
2J17
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2j17
PTYR BOUND FORM OF SDP-1
Descriptor:TYROSINE-PROTEIN PHOSPHATASE YIL113W (E.C.3.1.3.48)
Authors:Briggs, D.C., Mcdonald, N.Q.
Deposit date:2006-08-09
Release date:2007-05-22
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Redox-Mediated Substrate Recognition by Sdp1 Defines a New Group of Tyrosine Phosphatases
Nature, 447, 2007
2NT2
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2nt2
CRYSTAL STRUCTURE OF SLINGSHOT PHOSPHATASE 2
Descriptor:Protein phosphatase Slingshot homolog 2 (E.C.3.1.3.48, 3.1.3.16)
Authors:Jung, S.K., Jeong, D.G., Yoon, T.S., Kim, J.H., Ryu, S.E., Kim, S.J.
Deposit date:2006-11-06
Release date:2007-06-05
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human slingshot phosphatase 2.
Proteins, 68, 2007
2OUD
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2oud
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN MKP5
Descriptor:Dual specificity protein phosphatase 10 (E.C.3.1.3.48, 3.1.3.16)
Authors:Tao, X., Tong, L.
Deposit date:2007-02-10
Release date:2007-08-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the MAP kinase binding domain and the catalytic domain of human MKP5.
Protein Sci., 16, 2007
2P4D
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2p4d
STRUCTURE-ASSISTED DISCOVERY OF VARIOLA MAJOR H1 PHOSPHATASE INHIBITORS
Descriptor:Dual specificity protein phosphatase (E.C.3.1.3.48, 3.1.3.16)
Authors:Phan, J., Tropea, J.E., Waugh, D.S.
Deposit date:2007-03-12
Release date:2007-05-29
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-assisted discovery of variola major H1 phosphatase inhibitors
Acta Crystallogr.,Sect.D, D63, 2007
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