PDB: 29 resultsInfo pagesStatus searchChemie searchBIRD

---

1EBU	HOMOSERINE DEHYDROGENASE COMPLEX WITH NAD ANALOGUE AND L-HOMOSERINE Descriptor: 3-AMINOMETHYL-PYRIDINIUM-ADENINE-DINUCLEOTIDE, HOMOSERINE DEHYDROGENASE, L-HOMOSERINE, ... Authors: DeLaBarre, B, Thompson, P.R, Wright, G.D, Berghuis, A.M. Deposit date: 2000-01-24 Release date: 2000-03-08 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases. Nat.Struct.Biol., 7, 2000
1EBF	HOMOSERINE DEHYDROGENASE FROM S. CEREVISIAE COMPLEX WITH NAD+ Descriptor: HOMOSERINE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION Authors: DeLaBarre, B, Thompson, P.R, Wright, G.D, Berghuis, A.M. Deposit date: 2000-01-24 Release date: 2000-03-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases. Nat.Struct.Biol., 7, 2000
1Q7G	Homoserine Dehydrogenase in complex with suicide inhibitor complex NAD-5-hydroxy-4-Oxonorvaline Descriptor: Homoserine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE-5-HYDROXY-4-OXONORVALINE, SODIUM ION Authors: Jacques, S.L, Mirza, I.A, Ejim, L, Koteva, K, Hughes, D.W, Green, K, Kinach, R, Honek, J.F, Lai, H.K, Berghuis, A.M, Wright, G.D. Deposit date: 2003-08-18 Release date: 2003-10-21 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Enzyme assisted suicide: Molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase Chem.Biol., 10, 2003
1TVE	Homoserine Dehydrogenase in complex with 4-(4-hydroxy-3-isopropylphenylthio)-2-isopropylphenol Descriptor: 4-(4-HYDROXY-3-ISOPROPYLPHENYLTHIO)-2-ISOPROPYLPHENOL, Homoserine dehydrogenase Authors: Ejim, L, Mirza, I.A, Capone, C, Nazi, I, Jenkins, S, Chee, G.L, Berghuis, A.M, Wright, G.D. Deposit date: 2004-06-29 Release date: 2004-07-13 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3 Å) Cite: New phenolic inhibitors of yeast homoserine dehydrogenase Bioorg.Med.Chem., 12, 2004
2EJW	Homoserine Dehydrogenase from Thermus thermophilus HB8 Descriptor: GLYCEROL, Homoserine dehydrogenase, MAGNESIUM ION, ... Authors: Omi, R, Goto, M, Miyahara, I, Hirotsu, K. Deposit date: 2007-03-21 Release date: 2008-02-12 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal Structure of Homoserine Dehydrogenase from Thermus thermophilus HB8 To be Published
3C8M	Crystal structure of homoserine dehydrogenase from Thermoplasma volcanium Descriptor: Homoserine dehydrogenase, SULFATE ION Authors: Osipiuk, J, Hendricks, R, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2008-02-12 Release date: 2008-02-19 Last modified: 2017-10-25 Method: X-RAY DIFFRACTION (1.9 Å) Cite: X-ray crystal structure of homoserine dehydrogenase from Thermoplasma volcanium. To be Published
3DO5	Crystal structure of Putative Homoserine Dehydrogenase (NP_069768.1) from ARCHAEOGLOBUS FULGIDUS at 2.20 A resolution Descriptor: DI(HYDROXYETHYL)ETHER, Homoserine dehydrogenase, PHOSPHATE ION Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2008-07-03 Release date: 2008-09-02 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of Putative Homoserine Dehydrogenase (NP_069768.1) from ARCHAEOGLOBUS FULGIDUS at 2.20 A resolution To be published
3ING	Crystal structure of Homoserine dehydrogenase (NP_394635.1) from THERMOPLASMA ACIDOPHILUM at 1.95 A resolution Descriptor: 1,2-ETHANEDIOL, Homoserine dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2009-08-12 Release date: 2009-09-01 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of Homoserine dehydrogenase (NP_394635.1) from THERMOPLASMA ACIDOPHILUM at 1.95 A resolution To be published
3JSA	Homoserine dehydrogenase from Thermoplasma volcanium complexed with NAD Descriptor: Homoserine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION Authors: Osipiuk, J, Nocek, B, Hendricks, R, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2009-09-09 Release date: 2009-09-22 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (1.95 Å) Cite: X-ray crystal structure of Homoserine dehydrogenase from Thermoplasma volcanium To be Published
3MTJ	The Crystal Structure of a Homoserine Dehydrogenase from Thiobacillus denitrificans to 2.15A Descriptor: Homoserine dehydrogenase, SULFATE ION Authors: Stein, A.J, Cui, H, Chin, S, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2010-04-30 Release date: 2010-05-12 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (2.15 Å) Cite: The Crystal Structure of a Homoserine Dehydrogenase from Thiobacillus denitrificans to 2.15A To be Published
4PG4	Crystal structure of S. aureus Homoserine Dehydrogenase at pH6.0 Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... Authors: Navratna, V, Gopal, B. Deposit date: 2014-05-01 Release date: 2015-05-06 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis for the catalytic mechanism of homoserine dehydrogenase. Acta Crystallogr.,Sect.D, 71, 2015
4PG8	Crystal structure of S. aureus Homoserine Dehydrogenase at pH8.5 Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... Authors: Navratna, V, Gopal, B. Deposit date: 2014-05-01 Release date: 2015-05-06 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis for the catalytic mechanism of homoserine dehydrogenase. Acta Crystallogr.,Sect.D, 71, 2015
4PG5	Crystal structure of S. aureus Homoserine Dehydrogenase at pH6.5 Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... Authors: Navratna, V, Gopal, B. Deposit date: 2014-05-01 Release date: 2015-05-06 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis for the catalytic mechanism of homoserine dehydrogenase. Acta Crystallogr.,Sect.D, 71, 2015
4PG7	Crystal structure of S. aureus Homoserine Dehydrogenase at pH7.5 Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Navratna, V, Gopal, B. Deposit date: 2014-05-01 Release date: 2015-05-06 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis for the catalytic mechanism of homoserine dehydrogenase. Acta Crystallogr.,Sect.D, 71, 2015
4PG6	Crystal structure of S. aureus Homoserine Dehydrogenase at pH7.0 Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... Authors: Navratna, V, Gopal, B. Deposit date: 2014-05-01 Release date: 2015-05-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis for the catalytic mechanism of homoserine dehydrogenase. Acta Crystallogr.,Sect.D, 71, 2015
4XB2	Hyperthermophilic archaeal homoserine dehydrogenase mutant in complex with NADPH Descriptor: 319aa long hypothetical homoserine dehydrogenase, L-HOMOSERINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Sakuraba, H, Inoue, S, Yoneda, K, Ohshima, T. Deposit date: 2014-12-16 Release date: 2015-07-15 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.43 Å) Cite: Crystal Structures of a Hyperthermophilic Archaeal Homoserine Dehydrogenase Suggest a Novel Cofactor Binding Mode for Oxidoreductases. Sci Rep, 5, 2015
4XB1	Hyperthermophilic archaeal homoserine dehydrogenase in complex with NADPH Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 319aa long hypothetical homoserine dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Sakuraba, H, Inoue, S, Yoneda, K, Ohshima, T. Deposit date: 2014-12-16 Release date: 2015-07-15 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal Structures of a Hyperthermophilic Archaeal Homoserine Dehydrogenase Suggest a Novel Cofactor Binding Mode for Oxidoreductases. Sci Rep, 5, 2015
4YDR	Crystal structure of oxidized homoserine dehydrogenase of Sulfolobus tokodaii Descriptor: Homoserine dehydrogenase, SODIUM ION Authors: Goto, M, Yoshimune, K, Kaneko, R. Deposit date: 2015-02-23 Release date: 2015-11-11 Last modified: 2019-12-18 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural insight into activation of homoserine dehydrogenase from the archaeonSulfolobus tokodaiivia reduction. Biochem Biophys Rep, 3, 2015
5AVO	Crystal structure of the reduced form of homoserine dehydrogenase from Sulfolobus tokodaii. Descriptor: Homoserine dehydrogenase Authors: Goto, M, Yoshimune, K, Kaneko, R. Deposit date: 2015-06-25 Release date: 2015-11-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural insight into activation of homoserine dehydrogenase from the archaeonSulfolobus tokodaiivia reduction. Biochem Biophys Rep, 3, 2015
5XDF	Homoserine dehydrogenase from Thermus thermophilus HB8 complexed with HSE Descriptor: FORMIC ACID, Homoserine dehydrogenase, L-HOMOSERINE, ... Authors: Akai, S, Miyahara, I. Deposit date: 2017-03-28 Release date: 2017-04-26 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystallographic study of homoserine dehydrogenase from Thermus thermophilus HB8 To Be Published
5X9D	Crystal structure of homoserine dehydrogenase in complex with L-cysteine and NAD Descriptor: (2R)-3-[[(4S)-3-aminocarbonyl-1-[(2R,3R,4S,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]-4H-pyridin-4-yl]sulfanyl]-2-azanyl-propanoic acid, Homoserine dehydrogenase, L(+)-TARTARIC ACID Authors: Goto, M, Ogata, K, Kaneko, R, Yoshimune, K. Deposit date: 2017-03-06 Release date: 2018-05-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Inhibition of homoserine dehydrogenase by formation of a cysteine-NAD covalent complex Sci Rep, 8, 2018
6DZS	Mycobacterial homoserine dehydrogenase ThrA in complex with NADP Descriptor: Homoserine dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Chaton, C.T, Rodriguez, E.S, Korotkov, K.V. Deposit date: 2018-07-05 Release date: 2018-07-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.62 Å) Cite: Structure of mycobacterial homoserine dehydrogenase ThrA To be Published
6A0R	Homoserine dehydrogenase from Thermus thermophilus HB8 unliganded form Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, FORMIC ACID, GLYCEROL, ... Authors: Akai, S, Ikushiro, H, Sawai, T, Yano, T, Kamiya, N, Miyahara, I. Deposit date: 2018-06-06 Release date: 2018-11-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.83 Å) Cite: The crystal structure of homoserine dehydrogenase complexed with l-homoserine and NADPH in a closed form J. Biochem., 165, 2019
6A0S	Homoserine dehydrogenase from Thermus thermophilus HB8 complexed with HSE and NADPH Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, FORMIC ACID, GLYCEROL, ... Authors: Akai, S, Ikushiro, H, Sawai, T, Yano, T, Kamiya, N, Miyahara, I. Deposit date: 2018-06-06 Release date: 2018-11-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2 Å) Cite: The crystal structure of homoserine dehydrogenase complexed with l-homoserine and NADPH in a closed form J. Biochem., 165, 2019
6A0U	Homoserine dehydrogenase K195A mutant from Thermus thermophilus HB8 complexed with HSE and NADP+ Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, FORMIC ACID, GLYCEROL, ... Authors: Akai, S, Ikushiro, H, Sawai, T, Yano, T, Kamiya, N, Miyahara, I. Deposit date: 2018-06-06 Release date: 2018-11-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.93 Å) Cite: The crystal structure of homoserine dehydrogenase complexed with l-homoserine and NADPH in a closed form J. Biochem., 165, 2019

 

12>