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8CGY
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BU of 8cgy by Molmil
Trypanosoma brucei IMP dehydrogenase (ori) crystallized in High Five cells reveals native ligands ATP, GDP and phosphate. Diffraction data collection at 100 K in cellulo; XDS processing
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ...
Authors:Boger, J, Schoenherr, R, Lahey-Rudolph, J.M, Harms, M, Kaiser, J, Nachtschatt, S, Wobbe, M, Duden, R, Bourenkov, G, Schneider, T, Redecke, L.
Deposit date:2023-02-06
Release date:2024-02-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst.
Nat Commun, 15, 2024
8U7V
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BU of 8u7v by Molmil
Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by GTP, ATP, IMP, and NAD+, interface-centered
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ...
Authors:Calise, S.J, Kollman, J.M.
Deposit date:2023-09-15
Release date:2024-01-31
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly.
J.Cell Biol., 223, 2024
8U7M
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BU of 8u7m by Molmil
Human retinal variant phosphomimetic IMPDH1(595)-S477D free octamer bound by GTP, ATP, IMP, and NAD+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ...
Authors:Calise, S.J, Kollman, J.M.
Deposit date:2023-09-15
Release date:2024-01-31
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly.
J.Cell Biol., 223, 2024
8U8O
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BU of 8u8o by Molmil
Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by ATP, IMP, and NAD+, octamer-centered
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, ...
Authors:Calise, S.J, Kollman, J.M.
Deposit date:2023-09-18
Release date:2024-01-31
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly.
J.Cell Biol., 223, 2024
8U7Q
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BU of 8u7q by Molmil
Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by GTP, ATP, IMP, and NAD+, octamer-centered
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ...
Authors:Calise, S.J, Kollman, J.M.
Deposit date:2023-09-15
Release date:2024-01-31
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly.
J.Cell Biol., 223, 2024
8U8Y
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BU of 8u8y by Molmil
Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by ATP, IMP, and NAD+, interface-centered
Descriptor: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Calise, S.J, Kollman, J.M.
Deposit date:2023-09-18
Release date:2024-01-31
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly.
J.Cell Biol., 223, 2024
8C53
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BU of 8c53 by Molmil
Trypanosoma brucei IMP dehydrogenase (ori) crystallized in High Five cells reveals native ligands ATP, GDP and phosphate. Diffraction data collection at 100 K in cellulo; CrystFEL processing
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ...
Authors:Lahey-Rudolph, J.M, Schoenherr, R, Boger, J, Harms, M, Kaiser, J, Nachtschatt, S, Wobbe, M, Duden, R, Bourenkov, G, Schneider, T, Redecke, L.
Deposit date:2023-01-06
Release date:2024-01-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst.
Nat Commun, 15, 2024
8C51
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BU of 8c51 by Molmil
Trypanosoma brucei IMP dehydrogenase (cyto) crystallized in High Five cells revealing native ligands ATP, GDP and phosphate. Diffraction data collection at 100 K in cellulo
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ...
Authors:Lahey-Rudolph, J.M, Schoenherr, R, Boger, J, Harms, M, Kaiser, J, Nachtschatt, S, Wobbe, M, Duden, R, Koenig, P, Bourenkov, G, Schneider, T, Redecke, L.
Deposit date:2023-01-06
Release date:2024-01-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst.
Nat Commun, 15, 2024
8HVT
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BU of 8hvt by Molmil
Structure of the human CLC-7/Ostm1 complex reveals a novel state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H(+)/Cl(-) exchange transporter 7, Osteopetrosis-associated transmembrane protein 1, ...
Authors:Zhang, Z.X, Chen, L, He, J, She, J.
Deposit date:2022-12-27
Release date:2024-01-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of the human CLC-7/Ostm1 complex reveals a novel state
To Be Published
8JPO
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BU of 8jpo by Molmil
Cryo-EM structure of ATP bound human ClC-6
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, H(+)/Cl(-) exchange transporter 6, ...
Authors:Zhang, S.S.
Deposit date:2023-06-12
Release date:2023-09-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis of ClC-6 function and its impairment in human disease
Sci Adv, 2023
8JPJ
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BU of 8jpj by Molmil
Cryo-EM structure of ClC-6 apo state
Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter 6
Authors:Zhang, S.S.
Deposit date:2023-06-12
Release date:2023-09-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular basis of ClC-6 function and its impairment in human disease
Sci Adv, 2023
8JPR
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BU of 8jpr by Molmil
Cryo-EM structure of Y553C human ClC-6
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, H(+)/Cl(-) exchange transporter 6, ...
Authors:Zhang, S.S.
Deposit date:2023-06-12
Release date:2023-09-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis of ClC-6 function and its impairment in human disease
Sci Adv, 2023
8IAD
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BU of 8iad by Molmil
The Arabidopsis CLCa transporter bound with nitrate, ATP and PIP2
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Chloride channel protein CLC-a, MAGNESIUM ION, ...
Authors:Yang, Z, Zhang, X, Zhang, P.
Deposit date:2023-02-08
Release date:2023-08-02
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Molecular mechanism underlying regulation of Arabidopsis CLCa transporter by nucleotides and phospholipids.
Nat Commun, 14, 2023
8IAB
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BU of 8iab by Molmil
The Arabidopsis CLCa transporter bound with chloride, ATP and PIP2
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Chloride channel protein CLC-a, ...
Authors:Yang, Z, Zhang, X, Zhang, P.
Deposit date:2023-02-08
Release date:2023-08-02
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Molecular mechanism underlying regulation of Arabidopsis CLCa transporter by nucleotides and phospholipids.
Nat Commun, 14, 2023
8F6D
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BU of 8f6d by Molmil
Crystal structure of the CNNM2 CBS-pair domain in complex with ARL15
Descriptor: ADP-ribosylation factor-like protein 15, Metal transporter CNNM2
Authors:Kozlov, G, Mahbub, L, Gehring, K.
Deposit date:2022-11-16
Release date:2023-07-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into regulation of CNNM-TRPM7 divalent cation uptake by the small GTPase ARL15.
Elife, 12, 2023
7QEM
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BU of 7qem by Molmil
bacterial IMPDH chimera
Descriptor: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase
Authors:Labesse, G, Gelin, M, Gedeon, A, Haouz, A, Munier-Lehmann, H.
Deposit date:2021-12-03
Release date:2023-06-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases.
Protein Sci., 32, 2023
7QDX
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BU of 7qdx by Molmil
bacterial IMPDH chimera
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, MAGNESIUM ION
Authors:Labesse, G, Gelin, M, Munier-Lehmann, H, Gedeon, A, Haouz, A.
Deposit date:2021-11-30
Release date:2023-06-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases.
Protein Sci., 32, 2023
7QBJ
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BU of 7qbj by Molmil
bacterial IMPDH chimera
Descriptor: Inosine-5'-monophosphate dehydrogenase
Authors:Labesse, G, Gelin, M, Munier-Lehmann, H, Gedeon, A, Haouz, A.
Deposit date:2021-11-19
Release date:2023-05-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases.
Protein Sci., 32, 2023
8GPS
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BU of 8gps by Molmil
Cytoplasmic domain structure of the MgtE Mg2+ channel from Chryseobacterium hispalense
Descriptor: MAGNESIUM ION, MgtE
Authors:Wang, M, Zhao, Y, Hattori, M.
Deposit date:2022-08-27
Release date:2023-04-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Novel Mg 2+ binding sites in the cytoplasmic domain of the MgtE Mg 2+ channels revealed by X-ray crystal structures.
Acta Biochim.Biophys.Sin., 55, 2023
8GPV
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BU of 8gpv by Molmil
Cytoplasmic domain structure of the MgtE Mg2+ channel from Clostridiales bacterium
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, Magnesium transporter MgtE
Authors:Wang, M, Zhao, Y, Hattori, M.
Deposit date:2022-08-27
Release date:2023-04-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Novel Mg 2+ binding sites in the cytoplasmic domain of the MgtE Mg 2+ channels revealed by X-ray crystal structures.
Acta Biochim.Biophys.Sin., 55, 2023
8G8F
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BU of 8g8f by Molmil
Human IMPDH2 mutant - L245P, treated with ATP, IMP, and NAD+; extended filament segment reconstruction
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, ...
Authors:O'Neill, A.G, Kollman, J.M.
Deposit date:2023-02-17
Release date:2023-04-19
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
8G9B
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BU of 8g9b by Molmil
Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; compressed filament segment reconstruction
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ...
Authors:O'Neill, A.G, Kollman, J.M.
Deposit date:2023-02-21
Release date:2023-04-19
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
8FOZ
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BU of 8foz by Molmil
Human IMPDH2 mutant - L245P, treated with ATP, IMP, and NAD+; filament assembly interface reconstruction
Descriptor: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:O'Neill, A.G, Kollman, J.M.
Deposit date:2023-01-03
Release date:2023-04-19
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
8FUZ
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BU of 8fuz by Molmil
Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; filament assembly interface reconstruction
Descriptor: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:O'Neill, A.G, Kollman, J.M.
Deposit date:2023-01-18
Release date:2023-04-19
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
7XA9
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BU of 7xa9 by Molmil
Structure of Arabidopsis thaliana CLCa
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Chloride channel protein CLC-a, MAGNESIUM ION, ...
Authors:Ji, S, Jin, H, Kaiming, Z, Mingxing, W, Shanshan, L, Long, C.
Deposit date:2022-03-17
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Cryo-EM structure of the plant nitrate transporter AtCLCa reveals characteristics of the anion-binding site and the ATP-binding pocket.
J.Biol.Chem., 299, 2023

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PDB entries from 2024-03-27

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