3O53
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CRYSTAL STRUCTURE OF LRIM1 LEUCINE-RICH REPEAT DOMAIN
Descriptor:Protein LRIM1
Authors:Baxter, R.H.G., Steinert, S., Chelliah, Y., Volohonsky, G., Levashina, E.A., Deisenhofer, J.
Deposit date:2010-07-27
Release date:2010-09-22
Modification date:2011-01-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:A heterodimeric complex of the LRR proteins LRIM1 and APL1C regulates complement-like immunity in Anopheles gambiae.
Proc.Natl.Acad.Sci.USA, 107, 2010
3OJA
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CRYSTAL STRUCTURE OF LRIM1/APL1C COMPLEX
Descriptor:Leucine-rich Immune Molecule 1/Anopheles Plasmodium-responsive Leucine-rich repeat protein 1 complex
Authors:Baxter, R.H.G., Deisenhofer, J.
Deposit date:2010-08-20
Release date:2010-09-22
Modification date:2010-10-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A heterodimeric complex of the LRR proteins LRIM1 and APL1C regulates complement-like immunity in Anopheles gambiae.
Proc.Natl.Acad.Sci.USA, 107, 2010
4LSX
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PLANT STEROID RECEPTOR ECTODOMAIN BOUND TO BRASSINOLIDE AND SERK1 CO-RECEPTOR ECTODOMAIN
Descriptor:Protein BRASSINOSTEROID INSENSITIVE 1 (E.C.2.7.10.1, 2.7.11.1), Somatic embryogenesis receptor kinase 1 (E.C.2.7.10.1, 2.7.11.1)
Authors:Santiago, J., Henzler, C., Hothorn, M.
Deposit date:2013-07-23
Release date:2013-09-04
Method:X-RAY DIFFRACTION (3.302 Å)
Cite:Molecular mechanism for plant steroid receptor activation by somatic embryogenesis co-receptor kinases.
Science, 341, 2013
4M7E
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STRUCTURAL INSIGHT INTO BL-INDUCED ACTIVATION OF THE BRI1-BAK1 COMPLEX
Descriptor:Protein BRASSINOSTEROID INSENSITIVE 1 (E.C.2.7.10.1, 2.7.11.1), BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 (E.C.2.7.10.1, 2.7.11.1)
Authors:Chai, J., Han, Z., Sun, Y.
Deposit date:2013-08-12
Release date:2013-10-16
Method:X-RAY DIFFRACTION (3.602 Å)
Cite:Structural insight into BL-induced activation of the BRI1-BAK1 complex
To be Published
4MN8
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CRYSTAL STRUCTURE OF FLG22 IN COMPLEX WITH THE FLS2 AND BAK1 ECTODOMAINS
Descriptor:LRR receptor-like serine/threonine-protein kinase FLS2 (E.C.2.7.11.1), BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 (E.C.2.7.10.1, 2.7.11.1), flg22
Authors:Chai, J., Sun, Y., Han, Z.
Deposit date:2013-09-10
Release date:2013-12-04
Method:X-RAY DIFFRACTION (3.062 Å)
Cite:Structural basis for flg22-induced activation of the Arabidopsis FLS2-BAK1 immune complex.
Science, 342, 2013
2Z64
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CRYSTAL STRUCTURE OF MOUSE TLR4 AND MOUSE MD-2 COMPLEX
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96
Authors:Lee, J.-O., Kim, H.M., Park, B.S.
Deposit date:2007-07-22
Release date:2007-09-18
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
3B2D
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CRYSTAL STRUCTURE OF HUMAN RP105/MD-1 COMPLEX
Descriptor:CD180 antigen, Lymphocyte antigen 86
Authors:Ohto, U., Shimizu, T.
Deposit date:2011-07-29
Release date:2011-11-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structures of Mouse and Human RP105/MD-1 Complexes Reveal Unique Dimer Organization of the Toll-Like Receptor Family.
J.Mol.Biol., 413, 2011
3CIG
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CRYSTAL STRUCTURE OF MOUSE TLR3 ECTODOMAIN
Descriptor:Toll-like receptor 3
Authors:Liu, L., Botos, I., Wang, Y., Leonard, J.N., Shiloach, J., Segal, D.M., Davies, D.R.
Deposit date:2008-03-11
Release date:2008-05-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structural basis of toll-like receptor 3 signaling with double-stranded RNA.
Science, 320, 2008
3CIY
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MOUSE TOLL-LIKE RECEPTOR 3 ECTODOMAIN COMPLEXED WITH DOUBLE-STRANDED RNA
Descriptor:Toll-like receptor 3/RNA Complex
Authors:Liu, L., Botos, I., Wang, Y., Leonard, J.N., Shiloach, J., Segal, D.M., Davies, D.R.
Deposit date:2008-03-12
Release date:2008-05-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Structural basis of toll-like receptor 3 signaling with double-stranded RNA.
Science, 320, 2008
3RGX
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STRUCTURAL INSIGHT INTO BRASSINOSTEROID PERCEPTION BY BRI1
Descriptor:Protein BRASSINOSTEROID INSENSITIVE 1 (E.C.2.7.10.1, 2.7.11.1)
Authors:Chai, J., Han, Z., She, J., Wang, J., Cheng, W., Wang, J.
Deposit date:2011-04-11
Release date:2011-06-15
Modification date:2011-06-29
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structural insight into brassinosteroid perception by BRI1.
Nature, 474, 2011
3RGZ
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STRUCTURAL INSIGHT INTO BRASSINOSTEROID PERCEPTION BY BRI1
Descriptor:Protein BRASSINOSTEROID INSENSITIVE 1 (E.C.2.7.10.1, 2.7.11.1)
Authors:Chai, J., Han, Z., She, J., Wang, J., Cheng, W.
Deposit date:2011-04-11
Release date:2011-06-15
Modification date:2011-08-24
Method:X-RAY DIFFRACTION (2.281 Å)
Cite:Structural insight into brassinosteroid perception by BRI1.
Nature, 474, 2011
3RIZ
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CRYSTAL STRUCTURE OF THE PLANT STEROID RECEPTOR BRI1 ECTODOMAIN
Descriptor:Protein BRASSINOSTEROID INSENSITIVE 1 (E.C.2.7.10.1, 2.7.11.1)
Authors:Hothorn, M.
Deposit date:2011-04-14
Release date:2011-06-22
Modification date:2011-07-06
Method:X-RAY DIFFRACTION (2.523 Å)
Cite:Structural basis of steroid hormone perception by the receptor kinase BRI1.
Nature, 474, 2011
3RJ0
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PLANT STEROID RECEPTOR BRI1 ECTODOMAIN IN COMPLEX WITH BRASSINOLIDE
Descriptor:Protein BRASSINOSTEROID INSENSITIVE 1 (E.C.2.7.10.1, 2.7.11.1)
Authors:Hothorn, M.
Deposit date:2011-04-14
Release date:2011-06-22
Modification date:2011-07-06
Method:X-RAY DIFFRACTION (2.541 Å)
Cite:Structural basis of steroid hormone perception by the receptor kinase BRI1.
Nature, 474, 2011
3VQ1
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CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LIPID IVA COMPLEX
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96
Authors:Ohto, U., Shimizu, T.
Deposit date:2012-03-17
Release date:2012-05-09
Modification date:2013-07-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2
Proc.Natl.Acad.Sci.USA, 109, 2012
3VQ2
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CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LPS COMPLEX
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96
Authors:Ohto, U., Shimizu, T.
Deposit date:2012-03-17
Release date:2012-05-09
Modification date:2013-07-17
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2
Proc.Natl.Acad.Sci.USA, 109, 2012
3W3G
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CRYSTAL STRUCTURE OF HUMAN TLR8 (UNLIGANDED FORM)
Descriptor:Toll-like receptor 8
Authors:Tanji, H., Ohto, U., Shimizu, T.
Deposit date:2012-12-21
Release date:2013-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands
Science, 339, 2013
3W3J
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CRYSTAL STRUCTURE OF HUMAN TLR8 IN COMPLEX WITH CL097
Descriptor:Toll-like receptor 8
Authors:Tanji, H., Ohto, U., Shimizu, T.
Deposit date:2012-12-22
Release date:2013-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands
Science, 339, 2013
3W3K
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CRYSTAL STRUCTURE OF HUMAN TLR8 IN COMPLEX WITH CL075
Descriptor:Toll-like receptor 8
Authors:Tanji, H., Ohto, U., Shimizu, T.
Deposit date:2012-12-22
Release date:2013-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands
Science, 339, 2013
3W3L
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CRYSTAL STRUCTURE OF HUMAN TLR8 IN COMPLEX WITH RESIQUIMOD (R848) CRYSTAL FORM 1
Descriptor:Toll-like receptor 8
Authors:Tanji, H., Ohto, U., Shimizu, T.
Deposit date:2012-12-22
Release date:2013-04-03
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands
Science, 339, 2013
3W3M
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CRYSTAL STRUCTURE OF HUMAN TLR8 IN COMPLEX WITH RESIQUIMOD (R848) CRYSTAL FORM 2
Descriptor:Toll-like receptor 8
Authors:Tanji, H., Ohto, U., Shimizu, T.
Deposit date:2012-12-22
Release date:2013-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands
Science, 339, 2013
3W3N
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CRYSTAL STRUCTURE OF HUMAN TLR8 IN COMPLEX WITH RESIQUIMOD (R848) CRYSTAL FORM 3
Descriptor:Toll-like receptor 8
Authors:Tanji, H., Ohto, U., Shimizu, T.
Deposit date:2012-12-22
Release date:2013-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands
Science, 339, 2013
3WN4
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CRYSTAL STRUCTURE OF HUMAN TLR8 IN COMPLEX WITH DS-877
Descriptor:Toll-like receptor 8
Authors:Tanji, H., Ohto, U., Shimizu, T.
Deposit date:2013-12-02
Release date:2014-02-19
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structure-Based Design of Novel Human Toll-like Receptor 8 Agonists.
Chemmedchem, 2014
3WPB
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CRYSTAL STRUCTURE OF HORSE TLR9 (UNLIGANDED FORM)
Descriptor:Toll-like receptor 9
Authors:Ohto, U., Tanji, H., Shimizu, T.
Deposit date:2014-01-11
Release date:2015-02-11
Modification date:2015-05-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9
Nature, 520, 2015
3WPC
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CRYSTAL STRUCTURE OF HORSE TLR9 IN COMPLEX WITH AGONISTIC DNA1668_12MER
Descriptor:Toll-like receptor 9/DNA
Authors:Ohto, U., Tanji, H., Shimizu, T.
Deposit date:2014-01-11
Release date:2015-02-11
Modification date:2015-05-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9
Nature, 520, 2015
3WPD
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CRYSTAL STRUCTURE OF HORSE TLR9 IN COMPLEX WITH INHIBITORY DNA4084
Descriptor:Toll-like receptor 9/DNA
Authors:Ohto, U., Tanji, H., Shimizu, T.
Deposit date:2014-01-11
Release date:2015-02-11
Modification date:2015-05-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9
Nature, 520, 2015
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