PDB: 61 resultsInfo pagesStatus searchChemie searchBIRD

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6LUJ	Crystal structure of the SAMD1 SAM domain Descriptor: Atherin, SULFATE ION Authors: Cao, Y, Zhou, Y, Wang, Z. Deposit date: 2020-01-29 Release date: 2021-02-03 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.12 Å) Cite: The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands. Sci Adv, 7, 2021
5ZRY	Crystal Structure of EphA6/Odin Complex Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ankyrin repeat and SAM domain-containing protein 1A,Ephrin type-A receptor 6, ... Authors: Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. Deposit date: 2018-04-25 Release date: 2018-05-30 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions. Elife, 7, 2018
5ZRX	Crystal Structure of EphA2/SHIP2 Complex Descriptor: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,Ephrin type-A receptor 2 Authors: Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. Deposit date: 2018-04-25 Release date: 2018-05-30 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions. Elife, 7, 2018
4NL9	Crystal structure of the human Anks3-SAM/Anks6-SAM heterodimer Descriptor: Ankyrin repeat and SAM domain-containing protein 3, Ankyrin repeat and SAM domain-containing protein 6, MAGNESIUM ION Authors: Leettola, C.N, Cascio, D, Bowie, J.U. Deposit date: 2013-11-13 Release date: 2014-07-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3. Bmc Struct.Biol., 14, 2014
8J1I	Crystal Structure of EphA8/SASH1 Complex Descriptor: Ephrin type-A receptor 8, SAM and SH3 domain-containing protein 1 Authors: Liu, W, Li, J, Ding, Y. Deposit date: 2023-04-12 Release date: 2024-02-28 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure of EphA8 and SASH1 complex at 1.60 Angstroms resolution To Be Published
4NJ8	Crystal structure of the human ANKS3 SAM Domain L52A mutant Descriptor: Ankyrin repeat and SAM domain-containing protein 3 Authors: Leettola, C.N, Cascio, D, Bowie, J.U. Deposit date: 2013-11-08 Release date: 2014-07-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3. Bmc Struct.Biol., 14, 2014
4RQM	Crystal structure of the SeMET BICC1 SAM Domain R924E mutant Descriptor: Protein bicaudal C homolog 1, ZINC ION Authors: Leettola, C.N, Cascio, D, Bowie, J.U. Deposit date: 2014-11-03 Release date: 2016-01-27 Last modified: 2019-10-23 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6. Structure, 26, 2018
7KJA	Crystal structure of the EphA2 intracellular KD-SAM domains Descriptor: Ephrin type-A receptor 2, GLYCEROL, MAGNESIUM ION, ... Authors: Lechtenberg, B.C, Pasquale, E.B. Deposit date: 2020-10-26 Release date: 2021-02-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker. Nat Commun, 12, 2021
1OXJ	Crystal structure of the Smaug RNA binding domain Descriptor: RNA-binding protein Smaug Authors: Green, J.B, Gardner, C.D, Wharton, R.P, Aggarwal, A.K. Deposit date: 2003-04-02 Release date: 2003-07-08 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: RNA recognition via the SAM domain of Smaug. Mol.Cell, 11, 2003
1PK1	Hetero SAM domain structure of Ph and Scm. Descriptor: Polyhomeotic-proximal chromatin protein, Sex comb on midleg CG9495-PA Authors: Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U. Deposit date: 2003-06-04 Release date: 2005-02-15 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer. J.Biol.Chem., 280, 2005
1PK3	Scm SAM domain Descriptor: BETA-MERCAPTOETHANOL, Sex comb on midleg CG9495-PA Authors: Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U. Deposit date: 2003-06-04 Release date: 2005-02-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer. J.Biol.Chem., 280, 2005
5ZRZ	Crystal Structure of EphA5/SAMD5 Complex Descriptor: Ephrin type-A receptor 5, Sterile alpha motif domain-containing protein 5 Authors: Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. Deposit date: 2018-04-25 Release date: 2018-05-30 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions. Elife, 7, 2018
6KIP	Crystal structure of PTPRD phosphatase domain in complex with Liprin-alpha3 tandem SAM domains Descriptor: Liprin-alpha-3, Receptor-type tyrosine-protein phosphatase delta Authors: Wakita, M, Yamagata, A, Fukai, S. Deposit date: 2019-07-19 Release date: 2020-02-12 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.911 Å) Cite: Structural insights into selective interaction between type IIa receptor protein tyrosine phosphatases and Liprin-alpha. Nat Commun, 11, 2020
1B4F	OLIGOMERIC STRUCTURE OF THE HUMAN EPHB2 RECEPTOR SAM DOMAIN Descriptor: EPHB2 Authors: Thanos, C.D, Goodwill, K.E, Bowie, J.U. Deposit date: 1998-12-20 Release date: 1999-02-16 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Oligomeric structure of the human EphB2 receptor SAM domain. Science, 283, 1999
8B10	Crystal Structure of Shank2-SAM mutant domain - L1800W Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Bento, I, Gracia Alai, M, Kreienkamp, J.-H. Deposit date: 2022-09-08 Release date: 2022-11-30 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans. Mol Psychiatry, 2022
5J8Y	Crystal structure of the Scm-SAM and Sfmbt-SAM heterodimer Descriptor: Polycomb protein Scm, Polycomb protein Sfmbt Authors: Frey, F, Benda, C, Mueller, J. Deposit date: 2016-04-08 Release date: 2016-05-18 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Molecular basis of PRC1 targeting to Polycomb response elements by PhoRC. Genes Dev., 30, 2016
3HIL	SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1) Descriptor: CHLORIDE ION, Ephrin type-A receptor 1, NITRATE ION Authors: Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) Deposit date: 2009-05-20 Release date: 2009-06-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1). To be Published
4RQN	Crystal structure of the native BICC1 SAM Domain R924E mutant Descriptor: Protein bicaudal C homolog 1, ZINC ION Authors: Leettola, C.N, Cascio, D, Bowie, J.U. Deposit date: 2014-11-03 Release date: 2016-01-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6. Structure, 26, 2018
3BS5	Crystal Structure of hCNK2-SAM/dHYP-SAM Complex Descriptor: Connector enhancer of kinase suppressor of ras 2, Protein aveugle Authors: Rajakulendran, T, Ceccarelli, D.F, Kurinov, I, Sicheri, F. Deposit date: 2007-12-22 Release date: 2008-02-26 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling. Proc.Natl.Acad.Sci.USA, 105, 2008
6FXF	Crystal structure of the SAM domain of murine SLy1 Descriptor: SAM and SH3 domain-containing protein 3 Authors: Kukuk, L.K, Granzin, J, Batra-Safferling, R, Koenig, B.W. Deposit date: 2018-03-09 Release date: 2019-01-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structure of the SLy1 SAM homodimer reveals a new interface for SAM domain self-association. Sci Rep, 9, 2019
6LUK	Crystal structure of the SAMD1 SAM domain in another crystal form Descriptor: Atherin, SULFATE ION Authors: Cao, Y, Zhou, Y, Wang, Z. Deposit date: 2020-01-29 Release date: 2021-02-03 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.054 Å) Cite: The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands. Sci Adv, 7, 2021
2F3N	Crystal Structure of the native Shank SAM domain. Descriptor: SH3 and multiple ankyrin repeat domains 3 Authors: Baron, M.K, Bowie, J.U, Faham, S. Deposit date: 2005-11-22 Release date: 2006-02-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: An architectural framework that may lie at the core of the postsynaptic density. Science, 311, 2006
8BW8	Crystal structure of the dCNK-SAM-CRIC-PDZ/dHYP-SAM complex Descriptor: Connector enhancer of KSR protein CNK, GLYCEROL, Protein aveugle Authors: Maisonneuve, P, Kurinov, I, Sicheri, F. Deposit date: 2022-12-06 Release date: 2024-02-21 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction. Nat.Struct.Mol.Biol., 2024
2QKQ	Structure of the SAM Domain of Human Ephrin Type-B Receptor 4 Descriptor: CHLORIDE ION, Ephrin type-B receptor 4 Authors: Walker, J.R, Cuerrier, D, Butler-Cole, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) Deposit date: 2007-07-11 Release date: 2007-07-24 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.1 Å) Cite: SAM Domain of Human Ephrin Type-B Receptor 4 (EPHB4) TO BE PUBLISHED
8ATJ	Crystal Structure of Shank2-SAM domain Descriptor: CHLORIDE ION, FORMIC ACID, Isoform 4 of SH3 and multiple ankyrin repeat domains protein 2, ... Authors: Bento, I, Gracia Alai, M, Kreienkamp, J.-H. Deposit date: 2022-08-23 Release date: 2022-11-30 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.117 Å) Cite: Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans. Mol Psychiatry, 2022

 

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