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1AIK
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1aik
HIV GP41 CORE STRUCTURE
Descriptor:HIV-1 GP41 GLYCOPROTEIN
Authors:Chan, D.C., Fass, D., Berger, J.M., Kim, P.S.
Deposit date:1997-04-20
Release date:1997-06-16
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Core structure of gp41 from the HIV envelope glycoprotein.
Cell(Cambridge,Mass.), 89, 1997
1DF4
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1df4
INTERACTIONS BETWEEN HIV-1 GP41 CORE AND DETERGENTS AND THEIR IMPLICATIONS FOR MEMBRANE FUSION
Descriptor:HIV-1 ENVELOPE GLYCOPROTEIN GP41
Authors:Shu, W., Ji, H., Lu, M.
Deposit date:1999-11-17
Release date:1999-11-24
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Interactions between HIV-1 gp41 core and detergents and their implications for membrane fusion.
J.Biol.Chem., 275, 2000
1DF5
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1df5
INTERACTIONS BETWEEN HIV-1 GP41 CORE AND DETERGENTS AND THEIR IMPLICATIONS FOR MEMBRANE FUSION
Descriptor:HIV-1 ENVELOPE GLYCOPROTEIN GP41
Authors:Shu, W., Ji, H., Lu, M.
Deposit date:1999-11-17
Release date:1999-11-24
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Interactions between HIV-1 gp41 core and detergents and their implications for membrane fusion.
J.Biol.Chem., 275, 2000
1DLB
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1dlb
HELICAL INTERACTIONS IN THE HIV-1 GP41 CORE REVEALS STRUCTURAL BASIS FOR THE INHIBITORY ACTIVITY OF GP41 PEPTIDES
Descriptor:HIV-1 ENVELOPE GLYCOPROTEIN GP41
Authors:Shu, W., Liu, J., Ji, H., Rading, L., Jiang, S., Lu, M.
Deposit date:1999-12-09
Release date:1999-12-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Helical interactions in the HIV-1 gp41 core reveal structural basis for the inhibitory activity of gp41 peptides.
Biochemistry, 39, 2000
1ENV
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1env
ATOMIC STRUCTURE OF THE ECTODOMAIN FROM HIV-1 GP41
Descriptor:HIV-1 ENVELOPE PROTEIN CHIMERA CONSISTING OF A FRAGMENT OF GCN4 ZIPPER CLONED N-TERMINAL TO TWO FRAGMENTS OF GP41
Authors:Weissenhorn, W., Dessen, A., Harrison, S.C., Skehel, J.J., Wiley, D.C.
Deposit date:1997-06-27
Release date:1997-11-19
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Atomic structure of the ectodomain from HIV-1 gp41.
Nature, 387, 1997
1F23
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1f23
CONTRIBUTION OF A BURIED HYDROGEN BOND TO HIV-1 ENVELOPE GLYCOPROTEIN STRUCTURE AND FUNCTION
Descriptor:TRANSMEMBRANE GLYCOPROTEIN
Authors:Liu, J., Shu, W., Fagan, M., Nunberg, J.H., Lu, M.
Deposit date:2000-05-23
Release date:2001-06-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional analysis of the HIV gp41 core containing an Ile573 to Thr substitution: implications for membrane fusion.
Biochemistry, 40, 2001
1FAV
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1fav
THE STRUCTURE OF AN HIV-1 SPECIFIC CELL ENTRY INHIBITOR IN COMPLEX WITH THE HIV-1 GP41 TRIMERIC CORE
Descriptor:HIV-1 ENVELOPE PROTEIN CHIMERA/TRANSMEMBRANE GLYCOPROTEIN
Authors:Zhou, G., Ferrer, M., Chopra, R., Strassmaier, T., Weissenhorn, W., Skehel, J.J., Oprian, D., Schreiber, S.L., Harrison, S.C., Wiley, D.C.
Deposit date:2000-07-13
Release date:2000-08-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core.
Bioorg.Med.Chem., 8, 2000
1I5X
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1i5x
HIV-1 GP41 CORE
Descriptor:TRANSMEMBRANE GLYCOPROTEIN (GP41)
Authors:Liu, J., Lu, M.
Deposit date:2001-03-01
Release date:2002-09-10
Modification date:2011-11-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional analysis of interhelical interactions in the human immunodeficiency virus type 1 gp41 envelope glycoprotein by alanine-scanning mutagenesis.
J.Virol., 75, 2001
1I5Y
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1i5y
HIV-1 GP41 CORE
Descriptor:TRANSMEMBRANE GLYCOPROTEIN (GP41)
Authors:Liu, J., Lu, M.
Deposit date:2001-03-01
Release date:2002-09-10
Modification date:2011-11-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and functional analysis of interhelical interactions in the human immunodeficiency virus type 1 gp41 envelope glycoprotein by alanine-scanning mutagenesis.
J.Virol., 75, 2001
1JPX
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1jpx
MUTATION THAT DESTABILIZE THE GP41 CORE: DETERMINANTS FOR STABILIZING THE SIV/CPMAC ENVELOPE GLYCOPROTEIN COMPLEX. WILD TYPE.
Descriptor:gp41 envelope protein
Authors:Liu, J., Wang, S., LaBranche, C.C., Hoxie, J.A., Lu, M.
Deposit date:2001-08-03
Release date:2002-04-24
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mutations that destabilize the gp41 core are determinants for stabilizing the simian immunodeficiency virus-CPmac envelope glycoprotein complex.
J.Biol.Chem., 277, 2002
1JQ0
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1jq0
MUTATION THAT DESTABILIZE THE GP41 CORE: DETERMINANTS FOR STABILIZING THE SIV/CPMAC ENVELOPE GLYCOPROTEIN COMPLEX. MUTANT STRUCTURE.
Descriptor:gp41 envelope protein
Authors:Liu, J., Wang, S., LaBranche, C.C., Hoxie, J.A., Lu, M.
Deposit date:2001-08-03
Release date:2002-04-24
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mutations that destabilize the gp41 core are determinants for stabilizing the simian immunodeficiency virus-CPmac envelope glycoprotein complex.
J.Biol.Chem., 277, 2002
1K33
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1k33
CRYSTAL STRUCTURE ANALYSIS OF THE GP41 CORE MUTANT
Descriptor:Transmembrane glycoprotein GP41
Authors:Shu, W., Lu, M.
Deposit date:2001-10-01
Release date:2001-10-10
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion.
Biochemistry, 41, 2002
1K34
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1k34
CRYSTAL STRUCTURE ANALYSIS OF GP41 CORE MUTANT
Descriptor:Transmembrane glycoprotein GP41
Authors:Shu, W., Lu, M.
Deposit date:2001-10-01
Release date:2001-10-10
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion.
Biochemistry, 41, 2002
1QBZ
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1qbz
THE CRYSTAL STRUCTURE OF THE SIV GP41 ECTODOMAIN AT 1.47 A
Descriptor:SIV GP41 ECTODOMAIN
Authors:Yang, Z.-N., Mueser, T.C., Kaufman, J., Stahl, S.J., Wingfield, P.T., Hyde, C.C.
Deposit date:1999-04-28
Release date:1999-05-17
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:The crystal structure of the SIV gp41 ectodomain at 1.47 A resolution.
J.Struct.Biol., 126, 1999
1QCE
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1qce
SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, RESTRAINED REGULARIZED MEAN STRUCTURE PLUS 29 SIMULATED ANNEALING STRUCTURES
Descriptor:PROTEIN (GP41)
Authors:Clore, G.M.
Deposit date:1999-04-30
Release date:1999-07-18
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Measurement of Residual Dipolar Couplings of Macromolecules Aligned in the Nematic Phase of Acolloidal Suspension of Rod-Shaped Viruses
J.Am.Chem.Soc., 121, 1999
1QR9
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1qr9
INHIBITION OF HIV-1 INFECTIVITY BY THE GP41 CORE: ROLE OF A CONSERVED HYDROPHOBIC CAVITY IN MEMBRANE FUSION
Descriptor:SUBDOMAIN OF HIV-1 GP41
Authors:Ji, H., Shu, W., Burling, F.T., Jiang, S.B., Lu, M.
Deposit date:1999-06-18
Release date:1999-11-26
Modification date:2011-11-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Inhibition of human immunodeficiency virus type 1 infectivity by the gp41 core: role of a conserved hydrophobic cavity in membrane fusion.
J.Virol., 73, 1999
1SZT
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1szt
ATOMIC STRUCTURE OF A THERMOSTABLE SUBDOMAIN OF HIV-1 GP41
Descriptor:HIV-1 ENVELOPE GLYCOPROTEIN GP41
Authors:Tan, K., Lu, M., Wang, J.-H.
Deposit date:1997-07-28
Release date:1997-12-24
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Atomic structure of a thermostable subdomain of HIV-1 gp41.
Proc.Natl.Acad.Sci.USA, 94, 1997
2EZO
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2ezo
SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, RESTRAINED REGULARIZED MEAN STRUCTURE
Descriptor:GP41
Authors:Caffrey, M., Gronenborn, A.M., Clore, G.M.
Deposit date:1998-05-20
Release date:1998-10-14
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41.
EMBO J., 17, 1998
2EZP
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2ezp
SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, MODELS 1-10 OF AN ENSEMBLE OF 40 SIMULATED ANNEALING STRUCTURES
Descriptor:GP41
Authors:Caffrey, M., Gronenborn, A.M., Clore, G.M.
Deposit date:1998-05-20
Release date:1998-10-14
Modification date:2010-11-24
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41.
EMBO J., 17, 1998
2EZQ
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2ezq
SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, MODELS 11-20 OF AN ENSEMBLE OF 40 SIMULATED ANNEALING STRUCTURES
Descriptor:GP41
Authors:Caffrey, M., Gronenborn, A.M., Clore, G.M.
Deposit date:1998-05-20
Release date:1998-10-14
Modification date:2010-11-24
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41.
EMBO J., 17, 1998
2EZR
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2ezr
SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, MODELS 21-30 OF AN ENSEMBLE OF 40 SIMULATED ANNEALING STRUCTURES
Descriptor:GP41
Authors:Caffrey, M., Gronenborn, A.M., Clore, G.M.
Deposit date:1998-05-20
Release date:1998-10-14
Modification date:2010-11-24
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41.
EMBO J., 17, 1998
2EZS
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2ezs
SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, MODELS 31-40 OF AN ENSEMBLE OF 40 SIMULATED ANNEALING STRUCTURES
Descriptor:GP41
Authors:Caffrey, M., Gronenborn, A.M., Clore, G.M.
Deposit date:1998-05-20
Release date:1998-10-14
Modification date:2010-11-24
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41.
EMBO J., 17, 1998
2KP8
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2kp8
LIGAND BOUND TO A MODEL PEPTIDE THAT MIMICS THE OPEN FUSOGENIC FORM
Descriptor:entity_1
Authors:Olejniczak, E.T.
Deposit date:2009-10-09
Release date:2010-01-19
Method:SOLUTION NMR
Cite:Non-peptide entry inhibitors of HIV-1 that target the gp41 coiled coil pocket.
Bioorg.Med.Chem.Lett., 2009
2MK3
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2mk3
SOLUTION NMR STRUCTURE OF GP41 ECTODOMAIN MONOMER ON A DPC MICELLE
Descriptor:Transmembrane glycoprotein
Authors:Roche, J., Louis, J.M., Grishaev, A., Ying, J., Bax, A.
Deposit date:2014-01-23
Release date:2014-02-19
Modification date:2014-03-19
Method:SOLUTION NMR
Cite:Dissociation of the trimeric gp41 ectodomain at the lipid-water interface suggests an active role in HIV-1 Env-mediated membrane fusion.
Proc.Natl.Acad.Sci.USA, 111, 2014
2Z2T
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2z2t
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN GP41 FRAGMENT N36 AND FUSION INHIBITOR SC34EK
Descriptor:gp41 fragment N36, Fusion inhibitor peptide SC34EK
Authors:Nakamura, S., Ohkubo, T., Kobayashi, Y.
Deposit date:2007-05-28
Release date:2008-06-03
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Intrahelical Salt-bridges in a-Helical Peptide Enhances its Binding to the Target: A New Design for HIV-1 Fusion Inhibitors
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