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6Z2T	Three-dimensional structure of an influenza hemagglutinin LAH protein in its post-fusion conformation Descriptor: Hemagglutinin, PHOSPHATE ION Authors: Kirsteina, A, Kazaks, A, Tars, K. Deposit date: 2020-05-18 Release date: 2021-06-02 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.34 Å) Cite: Three-dimensional structure of an influenza hemagglutinin LAH protein To Be Published
6CHX	High Resolution Crystal Structure of the Hemagglutinin H1 Head Domain of Influenza A virus Solomon Islands Descriptor: Hemagglutinin Authors: Dong, J, Sevy, A.M, Crowe, J.E. Deposit date: 2018-02-23 Release date: 2019-02-27 Method: X-RAY DIFFRACTION (1.4 Å) Cite: High Resolution Crystal Structure of the Hemagglutinin H1 Head Domain of Influenza A virus Solomon Islands To Be Published
5DUT	Influenza A virus H5 hemagglutinin globular head Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin Authors: Zuo, T, Sun, J, Wang, G, Zhou, P, Wang, X, Zhang, L. Deposit date: 2015-09-20 Release date: 2015-12-16 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection Nat Commun, 6, 2015
7RCR	Crystal Structure of the refolded Hemagglutinin head domain of Influenza A virus A/Ohio/09/2015 Descriptor: 1,2-ETHANEDIOL, Hemagglutinin Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-07-08 Release date: 2021-08-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal Structure of the refolded Hemagglutinin head domain of Influenzavirus A Influenza A virus A/Ohio/09/2015 to be published
3KU3	Crystal structure of a H2N2 influenza virus hemagglutinin, avian like Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Xu, R, Wilson, I.A. Deposit date: 2009-11-26 Release date: 2010-01-19 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic. J.Virol., 84, 2010
6TVB	Crystal structure of the haemagglutinin from a transmissible H10N7 seal influenza virus isolated in Netherland in complex with human receptor analogue 6'-SLN Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... Authors: Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J. Deposit date: 2020-01-09 Release date: 2020-10-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals. Cell Host Microbe, 28, 2020
3QQI	Crystal structure of the HA1 receptor binding domain of H2 hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hemagglutinin Authors: Xu, R, Wilson, I.A. Deposit date: 2011-02-15 Release date: 2011-03-09 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structural Characterization of an Early Fusion Intermediate of Influenza Virus Hemagglutinin. J.Virol., 85, 2011
6AOR	Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin apo form Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA2 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-08-16 Release date: 2017-10-18 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.7 Å) Cite: A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13, 2017
4F23	Influenza A virus hemagglutinin H16 HA0 structure with an alpha-helix conformation in the cleavage site: a potential drug target Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin Authors: Lu, X, Shi, Y, Gao, F, Xiao, H, Qi, J, Gao, G.F. Deposit date: 2012-05-07 Release date: 2012-11-21 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Insights into Avian Influenza Virus Pathogenicity: the Hemagglutinin Precursor HA0 of Subtype H16 Has an Alpha-Helix Structure in Its Cleavage Site with Inefficient HA1/HA2 Cleavage. J.Virol., 86, 2012
4FQI	Crystal Structure of Fab CR9114 in Complex with a H5N1 influenza virus hemagglutinin Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Dreyfus, C, Wilson, I.A. Deposit date: 2012-06-25 Release date: 2012-08-22 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Highly conserved protective epitopes on influenza B viruses. Science, 337, 2012
3KU5	Crystal structure of a H2N2 influenza virus hemagglutinin, human like Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Xu, R, Wilson, I.A. Deposit date: 2009-11-26 Release date: 2010-01-19 Last modified: 2021-10-13 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic. J.Virol., 84, 2010
6TVA	Crystal structure of the haemagglutinin from a transmissible H10N7 seal influenza virus isolated in Netherland in complex with avian receptor analogue, 3'-SLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Haemagglutinin HA1, Haemagglutinin HA2, ... Authors: Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J. Deposit date: 2020-01-09 Release date: 2020-10-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals. Cell Host Microbe, 28, 2020
6NSB	Crystal structure of the IVR-165 (H3N2) influenza virus hemagglutinin in complex with 6'-SLNLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2019-01-24 Release date: 2019-04-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility. Cell Host Microbe, 25, 2019
6AOU	Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin in complex with 3'-SLNLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-08-16 Release date: 2017-10-18 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.75 Å) Cite: A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13, 2017
6AOV	Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin in complex with 6'-SLNLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-08-16 Release date: 2017-10-18 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.75 Å) Cite: A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13, 2017
4O5N	Crystal structure of A/Victoria/361/2011 (H3N2) influenza virus hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... Authors: Lee, P.S, Wilson, I.A. Deposit date: 2013-12-19 Release date: 2014-04-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nat Commun, 5, 2014
3KU6	Crystal structure of a H2N2 influenza virus hemagglutinin, 226L/228G Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Xu, R, Wilson, I.A. Deposit date: 2009-11-26 Release date: 2010-01-19 Last modified: 2021-10-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic. J.Virol., 84, 2010
6BKR	Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin in complex with 6'-SLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-11-09 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.76 Å) Cite: A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018
5XKU	Crystal structure of hemagglutinin globular head from an H7N9 influenza virus in complex with a neutralizing antibody HNIgGA6 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HNIgGA6 heavy chain, HNIgGA6 light chain, ... Authors: Chen, C, Wang, J, Wang, W, Gao, X, Cui, S, Jin, Q. Deposit date: 2017-05-09 Release date: 2017-11-29 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Structural Insight into a Human Neutralizing Antibody against Influenza Virus H7N9 J. Virol., 92, 2018
2YP9	Haemagglutinin of 2005 Human H3N2 Virus in Complex with Avian Receptor Analogue 3SLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Xiong, X, Lin, Y.P, Wharton, S.A, Martin, S.R, Coombs, P.J, Vachieri, S.G, Christodoulou, E, Walker, P.A, Liu, J, Skehel, J.J, Gamblin, S.J, Hay, A.J, Daniels, R.S, McCauley, J.W. Deposit date: 2012-10-29 Release date: 2012-11-07 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin. Proc.Natl.Acad.Sci.USA, 109, 2012
2YP5	Haemagglutinin of 2004 Human H3N2 Virus in Complex with Avian Receptor Analogue 3SLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Xiong, X, Lin, Y.P, Wharton, S.A, Martin, S.R, Coombs, P.J, Vachieri, S.G, Christodoulou, E, Walker, P.A, Liu, J, Skehel, J.J, Gamblin, S.J, Hay, A.J, Daniels, R.S, McCauley, J.W. Deposit date: 2012-10-29 Release date: 2012-11-07 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin. Proc.Natl.Acad.Sci.USA, 109, 2012
4GXX	Crystal structure of the "avianized" 1918 influenza virus hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... Authors: Ekiert, D.C, Wilson, I.A. Deposit date: 2012-09-04 Release date: 2012-12-19 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.799 Å) Cite: Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses. Plos Pathog., 8, 2012
5VLI	Computationally designed inhibitor peptide HB1.6928.2.3 in complex with influenza hemagglutinin (A/PuertoRico/8/1934) Descriptor: 2,5,8,11-TETRAOXATRIDECANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Bernard, S.M, Wilson, I.A. Deposit date: 2017-04-25 Release date: 2017-09-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.799 Å) Cite: Massively parallel de novo protein design for targeted therapeutics. Nature, 550, 2017
1JSD	CRYSTAL STRUCTURE OF SWINE H9 HAEMAGGLUTININ Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HAEMAGGLUTININ (HA1 CHAIN), ... Authors: Ha, Y, Steven, D.J, Skehel, J.J, Wiley, D.C. Deposit date: 2001-08-17 Release date: 2001-09-26 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes. EMBO J., 21, 2002
3UYX	Crystal structures of globular head of 2009 pandemic H1N1 hemagglutinin Descriptor: Hemagglutinin, NITRATE ION Authors: Xuan, C.L, Shi, Y, Qi, J.X, Xiao, H.X, Gao, G.F. Deposit date: 2011-12-06 Release date: 2012-10-24 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural vaccinology: structure-based design of influenza A virus hemagglutinin subtype-specific subunit vaccines Protein Cell, 2, 2011

 

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