PDB: 75 resultsInfo pagesStatus searchChemie searchBIRD

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8XGC	Structure of yeast replisome associated with FACT and histone hexamer, Composite map Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ... Authors: Li, N, Gao, Y, Yu, D, Gao, N, Zhai, Y. Deposit date: 2023-12-15 Release date: 2024-02-14 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Parental histone transfer caught at the replication fork. Nature, 627, 2024
8W7S	Yeast replisome in state IV Descriptor: Cell division control protein 45, DNA (71-mer), DNA polymerase alpha-binding protein, ... Authors: Dang, S, Zhai, Y, Feng, J, Yu, D. Deposit date: 2023-08-31 Release date: 2023-12-20 Method: ELECTRON MICROSCOPY (7.39 Å) Cite: Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
8W7M	Yeast replisome in state V Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (71-mer), ... Authors: Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. Deposit date: 2023-08-30 Release date: 2023-12-06 Method: ELECTRON MICROSCOPY (4.12 Å) Cite: Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
8KG6	Yeast replisome in state I Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ... Authors: Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. Deposit date: 2023-08-17 Release date: 2023-12-06 Method: ELECTRON MICROSCOPY (3.07 Å) Cite: Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
8KG8	Yeast replisome in state II Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ... Authors: Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. Deposit date: 2023-08-17 Release date: 2023-12-06 Method: ELECTRON MICROSCOPY (4.23 Å) Cite: Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
8KG9	Yeast replisome in state III Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ... Authors: Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. Deposit date: 2023-08-17 Release date: 2023-12-06 Method: ELECTRON MICROSCOPY (4.52 Å) Cite: Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
8Q6O	X. laevis CMG dimer bound to dimeric DONSON - without ATPase Descriptor: Cell division control protein 45 homolog, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ... Authors: Butryn, A, Cvetkovic, M.A, Costa, A. Deposit date: 2023-08-14 Release date: 2023-10-18 Last modified: 2023-11-29 Method: ELECTRON MICROSCOPY (3.14 Å) Cite: The structural mechanism of dimeric DONSON in replicative helicase activation. Mol.Cell, 83, 2023
8Q6P	X. laevis CMG dimer bound to dimeric DONSON - MCM ATPase Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA replication licensing factor mcm2, DNA replication licensing factor mcm4-B, ... Authors: Butryn, A, Cvetkovic, M.A, Costa, A. Deposit date: 2023-08-14 Release date: 2023-10-18 Last modified: 2023-11-29 Method: ELECTRON MICROSCOPY (3.53 Å) Cite: The structural mechanism of dimeric DONSON in replicative helicase activation. Mol.Cell, 83, 2023
8OUW	Cryo-EM structure of CMG helicase bound to TIM-1/TIPN-1 and homodimeric DNSN-1 on fork DNA (Caenorhabditis elegans) Descriptor: Cell division control protein 45 homolog, DNA Lagging Strand Template, DNA Leading Strand Template, ... Authors: Jenkyn-Bedford, M, Yeeles, J.T.P, Labib, K.P.M. Deposit date: 2023-04-25 Release date: 2023-08-16 Last modified: 2023-10-04 Method: ELECTRON MICROSCOPY (3.75 Å) Cite: DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in Caenorhabditis elegans. Science, 381, 2023
8S92	Structure of N-terminal domains of Walker B mutated MCM8/9 heterohexamer complex with ADP Descriptor: DNA helicase MCM8, DNA helicase MCM9 Authors: Li, C, Gao, Y. Deposit date: 2023-03-27 Release date: 2023-06-07 Last modified: 2023-08-23 Method: ELECTRON MICROSCOPY (4.06 Å) Cite: Activity, substrate preference and structure of the HsMCM8/9 helicase. Nucleic Acids Res., 51, 2023
8S94	Structure of C-terminal domains of Walker B mutated MCM8/9 heterohexamer complex with ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA helicase MCM8, DNA helicase MCM9, ... Authors: Li, C, Gao, Y. Deposit date: 2023-03-27 Release date: 2023-06-07 Last modified: 2023-08-23 Method: ELECTRON MICROSCOPY (3.94 Å) Cite: Activity, substrate preference and structure of the HsMCM8/9 helicase. Nucleic Acids Res., 51, 2023
8S91	Structure of Walker B mutated MCM8/9 heterohexamer complex with ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA helicase MCM8, DNA helicase MCM9, ... Authors: Li, C, Gao, Y. Deposit date: 2023-03-27 Release date: 2023-06-07 Last modified: 2023-08-23 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Activity, substrate preference and structure of the HsMCM8/9 helicase. Nucleic Acids Res., 51, 2023
8B9B	S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand. Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ... Authors: Jones, M.L, Yeeles, J.T.P. Deposit date: 2022-10-05 Release date: 2023-08-09 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
8B9A	S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand. Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ... Authors: Jones, M.L, Yeeles, J.T.P. Deposit date: 2022-10-05 Release date: 2023-08-09 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
8B9C	S. cerevisiae pol alpha - replisome complex Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ... Authors: Jones, M.L, Yeeles, J.T.P. Deposit date: 2022-10-05 Release date: 2023-08-09 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
8B9D	Human replisome bound by Pol Alpha Descriptor: Cell division control protein 45 homolog, Claspin, DNA Molecule, ... Authors: Jones, M.L, Yeeles, J.T.P. Deposit date: 2022-10-05 Release date: 2023-08-09 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
8EAH	SsoMCM hexamer bound to Mg/ADP-BeFx and 16-mer oligo-dT. Class 1 Descriptor: 16-mer oligo-dT, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... Authors: Meagher, M, Myasnikov, A, Enemark, E.J. Deposit date: 2022-08-29 Release date: 2022-12-14 Last modified: 2022-12-21 Method: ELECTRON MICROSCOPY (2.48 Å) Cite: Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation. Int J Mol Sci, 23, 2022
8EAI	SsoMCM hexamer bound to Mg/ADP-BeFx and 16-mer oligo-dT. Class 2 Descriptor: 16-mer oligo-dT, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... Authors: Meagher, M, Myasnikov, A, Enemark, E.J. Deposit date: 2022-08-29 Release date: 2022-12-14 Last modified: 2022-12-21 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation. Int J Mol Sci, 23, 2022
8EAJ	SsoMCM hexamer bound to Mg/ADP-BeFx and 46-mer DNA strand. Class 1 Descriptor: 46-mer DNA strand, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... Authors: Meagher, M, Myasnikov, A, Enemark, E.J. Deposit date: 2022-08-29 Release date: 2022-12-14 Last modified: 2022-12-21 Method: ELECTRON MICROSCOPY (2.45 Å) Cite: Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation. Int J Mol Sci, 23, 2022
8EAF	SsoMCM hexamer bound to Mg/ADP-BeFx and 12-mer oligo-dT. Class 1 Descriptor: 12-mer oligo dT, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... Authors: Meagher, M, Myasnikov, A, Enemark, E.J. Deposit date: 2022-08-29 Release date: 2022-12-14 Last modified: 2022-12-21 Method: ELECTRON MICROSCOPY (2.62 Å) Cite: Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation. Int J Mol Sci, 23, 2022
8EAL	SsoMCM hexamer bound to Mg/ADP-BeFx and DNA. Class 1. Merged particles from datasets with 3 different DNA entities Descriptor: DNA, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... Authors: Meagher, M, Myasnikov, A, Enemark, E.J. Deposit date: 2022-08-29 Release date: 2022-12-14 Last modified: 2022-12-21 Method: ELECTRON MICROSCOPY (2.34 Å) Cite: Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation. Int J Mol Sci, 23, 2022
8EAG	SsoMCM hexamer bound to Mg/ADP-BeFx and 12-mer oligo-dT. Class 2 Descriptor: 12-mer oligo-dT, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... Authors: Meagher, M, Myasnikov, A, Enemark, E.J. Deposit date: 2022-08-29 Release date: 2022-12-14 Last modified: 2022-12-21 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation. Int J Mol Sci, 23, 2022
8EAM	SsoMCM hexamer bound to Mg/ADP-BeFx and DNA. Class 2. Merged particles from datasets with 3 different DNA entities Descriptor: DNA, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... Authors: Meagher, M, Myasnikov, A, Enemark, E.J. Deposit date: 2022-08-29 Release date: 2022-12-14 Last modified: 2022-12-21 Method: ELECTRON MICROSCOPY (2.59 Å) Cite: Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation. Int J Mol Sci, 23, 2022
8EAK	SsoMCM hexamer bound to Mg/ADP-BeFx and 46-mer DNA strand. Class 2 Descriptor: 46-mer DNA, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... Authors: Meagher, M, Myasnikov, A, Enemark, E.J. Deposit date: 2022-08-29 Release date: 2022-12-14 Last modified: 2022-12-21 Method: ELECTRON MICROSCOPY (2.67 Å) Cite: Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation. Int J Mol Sci, 23, 2022
7Z13	S. cerevisiae CMGE dimer nucleating origin DNA melting Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, ... Authors: Lewis, J.S, Sousa, J.S, Costa, A. Deposit date: 2022-02-24 Release date: 2022-06-15 Last modified: 2022-07-06 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Mechanism of replication origin melting nucleated by CMG helicase assembly. Nature, 606, 2022

 

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