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1AW5
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1aw5
5-AMINOLEVULINATE DEHYDRATASE FROM SACCHAROMYCES CEREVISIAE
Descriptor:5-AMINOLEVULINATE DEHYDRATASE
Authors:Erskine, P.T., Cooper, J.B., Wood, S.P.
Deposit date:1997-10-09
Release date:1998-10-21
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray structure of 5-aminolaevulinate dehydratase, a hybrid aldolase.
Nat.Struct.Biol., 4, 1997
1B4E
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1b4e
X-RAY STRUCTURE OF 5-AMINOLEVULINIC ACID DEHYDRATASE COMPLEXED WITH THE INHIBITOR LEVULINIC ACID
Descriptor:PROTEIN (5-AMINOLEVULINIC ACID DEHYDRATASE) (4.2.1.24)
Authors:Erskine, P.T., Cooper, J.B., Lewis, G., Spencer, P., Wood, S.P., Shoolingin-Jordan, P.M.
Deposit date:1998-12-19
Release date:1999-12-17
Modification date:2012-01-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed with the inhibitor levulinic acid at 2.0 A resolution.
Biochemistry, 38, 1999
1B4K
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1b4k
HIGH RESOLUTION CRYSTAL STRUCTURE OF A MG2-DEPENDENT 5-AMINOLEVULINIC ACID DEHYDRATASE
Descriptor:PROTEIN (5-AMINOLEVULINIC ACID DEHYDRATASE) (4.2.1.24)
Authors:Frankenberg, N., Jahn, D., Heinz, D.W.
Deposit date:1998-12-22
Release date:1999-07-13
Modification date:2012-01-18
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:High resolution crystal structure of a Mg2+-dependent porphobilinogen synthase.
J.Mol.Biol., 289, 1999
1E51
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1e51
CRYSTAL STRUCTURE OF NATIVE HUMAN ERYTHROCYTE 5-AMINOLAEVULINIC ACID DEHYDRATASE
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Mills-Davies, N.L., Thompson, D., Cooper, J.B., Shoolingin-Jordan, P.M.
Deposit date:2000-07-13
Release date:2001-07-12
Modification date:2014-02-05
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:The Crystal Structure of Human Ala-Dehydratase
To be Published
1EB3
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1eb3
YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 4,7-DIOXOSEBACIC ACID COMPLEX
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Erskine, P.T., Coates, L., Newbold, R., Brindley, A.A., Stauffer, F., Wood, S.P., Warren, M.J., Cooper, J.B., Shoolingin-Jordan, P.M., Neier, R.
Deposit date:2001-07-18
Release date:2001-08-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Two Diacid Inhibitors
FEBS Lett., 503, 2001
1GJP
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1gjp
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 4-OXOSEBACIC ACID
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Erskine, P.T., Coates, L., Newbold, R., Brindley, A.A., Wood, S.P., Warren, M.J., Cooper, J.B., Shoolingin-Jordan, P.M., Neier, R.
Deposit date:2001-08-01
Release date:2001-08-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Two Diacid Inhibitors
FEBS Lett., 503, 2001
1GZG
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1gzg
COMPLEX OF A MG2-DEPENDENT PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA (MUTANT D139N) WITH 5-FLUOROLEVULINIC ACID
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Schubert, W.-D., Stauffer, F., Frankenberg, N., Neier, R., Jahn, D., Heinz, D.W.
Deposit date:2002-05-21
Release date:2002-06-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structure of Porphobilinogen Synthase from Pseudomonas Aeruginosa in Complex with 5-Fluorolevulinic Acid Suggests a Double Schiff Base Mechanism
J.Mol.Biol., 320, 2002
1H7N
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1h7n
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH LAEVULINIC ACID AT 1.6 A RESOLUTION
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Erskine, P.T., Newbold, R., Brindley, A.A., Wood, S.P., Shoolingin-Jordan, P.M., Warren, M.J., Cooper, J.B.
Deposit date:2001-07-09
Release date:2001-07-10
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors
J.Mol.Biol., 312, 2001
1H7O
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1h7o
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 5-AMINOLAEVULINIC ACID AT 1.7 A RESOLUTION
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Erskine, P.T., Newbold, R., Brindley, A.A., Wood, S.P., Shoolingin-Jordan, P.M., Warren, M.J., Cooper, J.B.
Deposit date:2001-07-09
Release date:2001-07-10
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors
J.Mol.Biol., 312, 2001
1H7P
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1h7p
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 4-KETO-5-AMINO-HEXANOIC (KAH) AT 1.64 A RESOLUTION
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Erskine, P.T., Newbold, R., Brindley, A.A., Wood, S.P., Shoolingin-Jordan, P.M., Warren, M.J., Cooper, J.B.
Deposit date:2001-07-09
Release date:2001-07-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors
J.Mol.Biol., 312, 2001
1H7R
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1h7r
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH SUCCINYLACETONE AT 2.0 A RESOLUTION.
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Erskine, P.T., Newbold, R., Brindley, A.A., Wood, S.P., Shoolingin-Jordan, P.M., Warren, M.J., Cooper, J.B.
Deposit date:2001-07-09
Release date:2001-07-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors
J.Mol.Biol., 312, 2001
1I8J
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1i8j
CRYSTAL STRUCTURE OF PORPHOBILINOGEN SYNTHASE COMPLEXED WITH THE INHIBITOR 4,7-DIOXOSEBACIC ACID
Descriptor:PORPHOBILINOGEN SYNTHASE (E.C.4.2.1.24).
Authors:Kervinen, J., Jaffe, E.K., Stauffer, F., Neier, R., Wlodawer, A., Zdanov, A.
Deposit date:2001-03-14
Release date:2001-06-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanistic basis for suicide inactivation of porphobilinogen synthase by 4,7-dioxosebacic acid, an inhibitor that shows dramatic species selectivity.
Biochemistry, 40, 2001
1L6S
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1l6s
CRYSTAL STRUCTURE OF PORPHOBILINOGEN SYNTHASE COMPLEXED WITH THE INHIBITOR 4,7-DIOXOSEBACIC ACID
Descriptor:PORPHOBILINOGEN SYNTHASE (E.C.4.2.1.24)
Authors:Jaffe, E.K., Kervinen, J., Martins, J., Stauffer, F., Neier, R., Wlodawer, A., Zdanov, A.
Deposit date:2002-03-13
Release date:2002-04-17
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Species-Specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid
J.Biol.Chem., 277, 2002
1L6Y
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1l6y
CRYSTAL STRUCTURE OF PORPHOBILINOGEN SYNTHASE COMPLEXED WITH THE INHIBITOR 4-OXOSEBACIC ACID
Descriptor:PORPHOBILINOGEN SYNTHASE (E.C.4.2.1.24)
Authors:Jaffe, E.K., Kervinen, J., Martins, J., Stauffer, F., Neier, R., Wlodawer, A., Zdanov, A.
Deposit date:2002-03-14
Release date:2002-04-17
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Species-Specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid
J.Biol.Chem., 277, 2002
1OHL
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1ohl
YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE PUTATIVE CYCLIC REACTION INTERMEDIATE COMPLEX
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Erskine, P.T., Coates, L., Butler, D., Youell, J.H., Brindley, A.A., Wood, S.P., Warren, M.J., Shoolingin-Jordan, P.M., Cooper, J.B.
Deposit date:2003-05-27
Release date:2003-06-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-Ray Structure of a Putative Reaction Intermediateof 5-Aminolaevulinic Acid Dehydratase
Biochem.J., 373, 2003
1PV8
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1pv8
CRYSTAL STRUCTURE OF A LOW ACTIVITY F12L MUTANT OF HUMAN PORPHOBILINOGEN SYNTHASE
Descriptor:Delta-aminolevulinic acid dehydratase (E.C.4.2.1.24)
Authors:Breinig, S., Kervinen, J., Stith, L., Wasson, A.S., Fairman, R., Wlodawer, A., Zdanov, A., Jaffe, E.K.
Deposit date:2003-06-26
Release date:2003-09-09
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase.
Nat.Struct.Biol., 10, 2003
1QML
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1qml
HG COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Erskine, P.T., Senior, N., Warren, M.J., Wood, S.P., Cooper, J.B.
Deposit date:1999-10-02
Release date:2000-10-06
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:MAD Analyses of Yeast 5-Aminolaevulinic Acid Dehydratase. Their Use in Structure Determination and in Defining the Metal Binding Sites
Acta Crystallogr.,Sect.D, 56, 2000
1QNV
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1qnv
YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE LEAD (PB) COMPLEX
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Erskine, P.T., Senior, N.M., Warren, M.J., Wood, S.P., Cooper, J.B.
Deposit date:1999-10-21
Release date:2000-10-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:MAD Analyses of Yeast 5-Aminolaevulinic Acid Dehydratase. Their Use in Structure Determination and in Defining the Metal Binding Sites
Acta Crystallogr.,Sect.D, 56, 2000
1W1Z
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1w1z
STRUCTURE OF THE PLANT LIKE 5-AMINOLAEVULINIC ACID DEHYDRATASE FROM CHLOROBIUM VIBRIOFORME
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Coates, L., Beaven, G., Erskine, P.T., Beale, S.I., Avissar, Y.J., Gill, R., Mohammed, F., Wood, S.P., Shoolingin-Jordan, P., Cooper, J.B.
Deposit date:2004-06-24
Release date:2004-09-02
Modification date:2011-12-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The X-Ray Structure of the Plant Like 5-Aminolaevulinic Acid Dehydratase from Chlorobium Vibrioforme Complexed with the Inhibitor Laevulinic Acid at 2.6A Resolution
J.Mol.Biol., 342, 2004
1W31
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1w31
YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 5-HYDROXYLAEVULINIC ACID COMPLEX
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Erskine, P.T., Coates, L., Newbold, R., Brindley, A.A., Stauffer, F., Beaven, G.D.E., Gill, R., Wood, S.P., Warren, M.J., Cooper, J.B., Shoolingin-Jordan, P.M., Neier, R.
Deposit date:2004-07-11
Release date:2005-08-23
Modification date:2014-08-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with the Inhibitor 5-Hydroxylaevulinic Acid
Acta Crystallogr.,Sect.D, 61, 2005
1W54
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1w54
STEPWISE INTRODUCTION OF A ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA (MUTATION D139C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-05
Release date:2005-01-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W56
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1w56
STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS A129C AND D131C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-05
Release date:2005-01-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W5M
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1w5m
STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS A129C AND D139C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-09
Release date:2005-01-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W5N
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1w5n
STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS D131C AND D139C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-09
Release date:2005-01-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W5O
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1w5o
STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS A129C, D131C AND D139C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-09
Release date:2005-01-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
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