5IC2
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PRODUCT-COMPLEX OF E.COLI 5-AMINO LAEVULINIC ACID DEHYDRATASE
Descriptor:Delta-aminolevulinic acid dehydratase (E.C.4.2.1.24)
Authors:Norton, E., Erskine, P.T., Shoolingin-Jordan, P.M., Cooper, J.B.
Deposit date:2016-02-22
Release date:2016-03-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Studies of Substrate- and Product-Complexes of Aminolaevulinic Acid Dehydratase from Humans, E.Coli and the Hyperthermophile Pyrobaculum Calidifontis
To Be Published
5HNR
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THE X-RAY STRUCTURE OF OCTAMERIC HUMAN NATIVE 5-AMINOLAEVULINIC ACID DEHYDRATASE.
Descriptor:Delta-aminolevulinic acid dehydratase (E.C.4.2.1.24)
Authors:Mills-Davies, N.L., Thompson, D., Shoolingin-Jordan, P.M., Erskine, P.T., Cooper, J.B.
Deposit date:2016-01-18
Release date:2016-01-27
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Structural Studies of Substrate- and Product-Complexes of 5-Aminolaevulinic Acid Dehydratase from Humans, E. Coli and the Hyperthermophile Pyrobaculum Calidifontis.
To be published
5HMS
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X-RAY STRUCTURE OF HUMAN RECOMBINANT 5-AMINOLAEVULINIC ACID DEHYDRATASE (HRALAD).
Descriptor:Delta-aminolevulinic acid dehydratase (E.C.4.2.1.24)
Authors:Butler, D., Erskine, P.T., Cooper, J.B., Shoolingin-Jordan, P.M.
Deposit date:2016-01-17
Release date:2016-01-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Studies of Substrate- and Product-Complexes of 5-Aminolaevulinic Acid Dehydratase from Humans, E. Coli and the Hyperthermophile Pyrobaculum Calidifontis.
to be published
3OBK
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CRYSTAL STRUCTURE OF DELTA-AMINOLEVULINIC ACID DEHYDRATASE (PORPHOBILINOGEN SYNTHASE) FROM TOXOPLASMA GONDII ME49 IN COMPLEX WITH THE REACTION PRODUCT PORPHOBILINOGEN
Descriptor:Delta-aminolevulinic acid dehydratase (E.C.4.2.1.24)
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-08-06
Release date:2010-09-15
Modification date:2011-05-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Toxoplasma gondii Porphobilinogen Synthase: INSIGHTS ON OCTAMERIC STRUCTURE AND PORPHOBILINOGEN FORMATION.
J.Biol.Chem., 286, 2011
2Z1B
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CRYSTAL STRUCTURE OF 5-AMINOLEVULINIC ACID DEHYDRATASE (ALAD) FROM MUS MUSCULS
Descriptor:Delta-aminolevulinic acid dehydratase (E.C.4.2.1.24)
Authors:Xie, Y., Wang, H., Kawazoe, M., Kishishita, S., Murayama, K., Takemoto, C., Terada, T., Shirozu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-08
Release date:2008-05-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal Structure of 5-aminolevulinic acid dehydratase (ALAD) from Mus musculs
To be Published
2Z0I
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CRYSTAL STRUCTURE OF 5-AMINOLEVULINIC ACID DEHYDRATASE (ALAD) FROM MUS MUSCULUS
Descriptor:Delta-aminolevulinic acid dehydratase (E.C.4.2.1.24)
Authors:Wang, H., Xie, Y., Kawazoe, M., Kishishita, S., Murayama, K., Takemoto, C., Terada, T., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-07
Release date:2008-05-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal Structure of 5-aminolevulinic acid dehydratase (ALAD) from Mus musculus
To be Published
2WOQ
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PORPHOBILINOGEN SYNTHASE (HEMB) IN COMPLEX WITH 5-ACETAMIDO-4-OXOHEXANOIC ACID (ALAREMYCIN 2)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Heinemann, I.U., Schulz, C., Schubert, W.-D., Heinz, D.W., Wang, Y.-G., Kobayashi, Y., Awa, Y., Wachi, M., Jahn, D., Jahn, M.
Deposit date:2009-07-27
Release date:2009-10-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of the Heme Biosynthetic Pseudomonas Aeruginosa Porphobilinogen Synthase in Complex with the Antibiotic Alaremycin.
Antimicrob.Agents Chemother., 54, 2010
2C19
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5-(4-CARBOXY-2-OXO-BUTYLSULFANYL)-4-OXO-PENTANOIC ACID ACID BOUND TO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Nentwich, M., Gacond, S., Heinz, D.W., Neier, R., Frankenberg-Dinkel, N.
Deposit date:2005-09-11
Release date:2006-06-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45, 2006
2C18
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5-(4-CARBOXY-2-OXO-BUTANE-1-SULFONYL)-4-OXO-PENTANOIC ACID BOUND TO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Nentwich, M., Gacond, S., Heinz, D.W., Neier, R., Frankenberg-Dinkel, N.
Deposit date:2005-09-11
Release date:2006-06-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45, 2006
2C16
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5-(4-CARBOXY-2-OXO-BUTANE-1-SULFINYL)-4-OXO-PENTANOIC ACID ACID BOUND TO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Nentwich, M., Gacond, S., Heinz, D.W., Neier, R., Frankenberg-Dinkel, N.
Deposit date:2005-09-11
Release date:2006-06-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45, 2006
2C15
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5-(4-CARBOXY-2-OXO-BUTOXY)-4-OXO-PENTANOIC ACID ACID BOUND TO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Nentwich, M., Gacond, S., Heinz, D.W., Neier, R., Frankenberg-Dinkel, N.
Deposit date:2005-09-11
Release date:2006-06-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45, 2006
2C14
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5-(4-CARBOXY-2-OXO-BUTYLAMINO)-4-OXO-PENTANOIC ACID ACID BOUND TO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Nentwich, M., Gacond, S., Heinz, D.W., Neier, R., Frankenberg-Dinkel, N.
Deposit date:2005-09-11
Release date:2006-06-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45, 2006
2C13
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5-HYDROXY-LEVULINIC ACID BOUND TO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Nentwich, M., Gacond, S., Heinz, D.W., Neier, R., Frankenberg-Dinkel, N.
Deposit date:2005-09-11
Release date:2006-06-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45, 2006
1YLV
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SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH LAEVULINIC ACID
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE + LAEVULINIC ACID
Authors:Erskine, P.T., Newbold, R., Roper, J., Coker, A., Warren, M.J., Shoolingin-Jordan, P.M., Wood, S.P., Cooper, J.B.
Deposit date:1999-02-22
Release date:2000-02-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Schiff base complex of yeast 5-aminolaevulinic acid dehydratase with laevulinic acid.
Protein Sci., 8, 1999
1W5Q
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STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS A129C, D131C, D139C, P132E, K229R)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-09
Release date:2005-01-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W5P
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STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS A129C, D131C, D139C, P132E)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-09
Release date:2005-01-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W5O
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STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS A129C, D131C AND D139C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-09
Release date:2005-01-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W5N
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STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS D131C AND D139C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-09
Release date:2005-01-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W5M
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STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS A129C AND D139C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-09
Release date:2005-01-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W56
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STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS A129C AND D131C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-05
Release date:2005-01-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W54
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STEPWISE INTRODUCTION OF A ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA (MUTATION D139C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-05
Release date:2005-01-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W31
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YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 5-HYDROXYLAEVULINIC ACID COMPLEX
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Erskine, P.T., Coates, L., Newbold, R., Brindley, A.A., Stauffer, F., Beaven, G.D.E., Gill, R., Wood, S.P., Warren, M.J., Cooper, J.B., Shoolingin-Jordan, P.M., Neier, R.
Deposit date:2004-07-11
Release date:2005-08-23
Modification date:2014-08-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with the Inhibitor 5-Hydroxylaevulinic Acid
Acta Crystallogr.,Sect.D, 61, 2005
1QNV
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YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE LEAD (PB) COMPLEX
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Erskine, P.T., Senior, N.M., Warren, M.J., Wood, S.P., Cooper, J.B.
Deposit date:1999-10-21
Release date:2000-10-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:MAD Analyses of Yeast 5-Aminolaevulinic Acid Dehydratase. Their Use in Structure Determination and in Defining the Metal Binding Sites
Acta Crystallogr.,Sect.D, 56, 2000
1QML
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HG COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE
Descriptor:5-AMINOLAEVULINIC ACID DEHYDRATASE (E.C.4.2.1.24)
Authors:Erskine, P.T., Senior, N., Warren, M.J., Wood, S.P., Cooper, J.B.
Deposit date:1999-10-02
Release date:2000-10-06
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:MAD Analyses of Yeast 5-Aminolaevulinic Acid Dehydratase. Their Use in Structure Determination and in Defining the Metal Binding Sites
Acta Crystallogr.,Sect.D, 56, 2000
1PV8
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CRYSTAL STRUCTURE OF A LOW ACTIVITY F12L MUTANT OF HUMAN PORPHOBILINOGEN SYNTHASE
Descriptor:Delta-aminolevulinic acid dehydratase (E.C.4.2.1.24)
Authors:Breinig, S., Kervinen, J., Stith, L., Wasson, A.S., Fairman, R., Wlodawer, A., Zdanov, A., Jaffe, E.K.
Deposit date:2003-06-26
Release date:2003-09-09
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase.
Nat.Struct.Biol., 10, 2003
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