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1HIB
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1hib
THE STRUCTURE OF AN INTERLEUKIN-1 BETA MUTANT WITH REDUCED BIOACTIVITY SHOWS MULTIPLE SUBTLE CHANGES IN CONFORMATION THAT AFFECT PROTEIN-PROTEIN RECOGNITION
Descriptor:INTERLEUKIN-1 BETA (HUMAN) MUTANT WITH THR 9 REPLACED BY GLY (T9G)
Authors:Camacho, N.P., Smith, D.R., Goldman, A., Schneider, B., Green, D., Young, P.R., Berman, H.M.
Deposit date:1993-03-29
Release date:1994-01-31
Modification date:2011-11-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of an interleukin-1 beta mutant with reduced bioactivity shows multiple subtle changes in conformation that affect protein-protein recognition.
Biochemistry, 32, 1993
1I1B
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1i1b
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-1BETA AT 2.0 ANGSTROMS RESOLUTION
Descriptor:INTERLEUKIN-1 BETA (IL-1 BETA)
Authors:Finzel, B.C., Watenpaugh, K.D., Einspahr, H.M.
Deposit date:1989-12-05
Release date:1990-01-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of recombinant human interleukin-1 beta at 2.0 A resolution.
J.Mol.Biol., 209, 1989
1ILR
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1ilr
CRYSTAL STRUCTURE OF THE INTERLEUKIN-1 RECEPTOR ANTAGONIST
Descriptor:INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN (IL-1RA)
Authors:Schreuder, H.A., Rondeau, J.-M., Tardif, C.
Deposit date:1994-06-20
Release date:1995-02-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Refined crystal structure of the interleukin-1 receptor antagonist. Presence of a disulfide link and a cis-proline.
Eur.J.Biochem., 227, 1995
1ILT
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1ilt
X-RAY STRUCTURE OF INTERLEUKIN-1 RECEPTOR ANTAGONIST AT 2.0 ANGSTROMS RESOLUTION
Descriptor:INTERLEUKIN-1 RECEPTOR ANTAGONIST (IL-1RA) (ALPHA CARBONS)
Authors:Brandhuber, B.J., Vigers, G.P.A.
Deposit date:1994-03-09
Release date:1995-04-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of interleukin-1 receptor antagonist at 2.0-A resolution.
J.Biol.Chem., 269, 1994
1IOB
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1iob
INTERLEUKIN-1 BETA FROM JOINT X-RAY AND NMR REFINEMENT
Descriptor:INTERLEUKIN-1 BETA
Authors:Shaanan, B., Clore, G.M.
Deposit date:1996-03-14
Release date:1996-08-17
Modification date:2009-02-24
Method:X-RAY DIFFRACTION, SOLUTION NMR, HYBRID (2 Å)
Cite:Combining experimental information from crystal and solution studies: joint X-ray and NMR refinement.
Science, 257, 1992
1IRP
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1irp
SOLUTION STRUCTURE OF HUMAN INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN
Descriptor:INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN (NMR, 12 STRUCTURES)
Authors:Stockman, B.J., Scahill, T.A., Strakalaitis, N.A.
Deposit date:1994-10-18
Release date:1995-02-27
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of human interleukin-1 receptor antagonist protein.
FEBS Lett., 349, 1994
1J0S
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1j0s
SOLUTION STRUCTURE OF THE HUMAN INTERLEUKIN-18
Descriptor:interleukin-18
Authors:Kato, Z., Jee, J., Shikano, H., Mishima, M., Ohki, I., Yoneda, T., Hara, T., Torigoe, K., Kondo, N., Shirakawa, M.
Deposit date:2002-11-21
Release date:2003-11-11
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The structure and binding mode of interleukin-18
Nat.Struct.Biol., 10, 2003
1L2H
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1l2h
CRYSTAL STRUCTURE OF INTERLEUKIN 1-BETA F42W/W120F MUTANT
Descriptor:Interleukin 1-beta
Authors:Rudolph, M.G., Kelker, M.S., Schneider, T.R., Yeates, T.O., Oseroff, V., Heidary, D.K., Jennings, P.A., Wilson, I.A.
Deposit date:2002-02-21
Release date:2003-02-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta.
Acta Crystallogr.,Sect.D, 59, 2003
1MD6
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1md6
HIGH RESOLUTION CRYSTAL STRUCTURE OF MURINE IL-1F5 REVEALS UNIQUE LOOP CONFORMATION FOR SPECIFICITY
Descriptor:interleukin 1 family, member 5 (delta)
Authors:Pei, X.Y., Dunn, E.F., Gay, N.J., O'Neill, L.A.
Deposit date:2002-08-07
Release date:2003-09-30
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:High-Resolution Structure of Murine Interleukin 1 Homologue IL-1F5 Reveals Unique Loop Conformations for Receptor Binding Specificity.
Biochemistry, 42, 2003
1S0L
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1s0l
INTERLEUKIN 1 BETA MUTANT F42W
Descriptor:Interleukin-1 beta
Authors:Adamek, D.H., Guerrero, L., Caspar, D.L.D.
Deposit date:2003-12-31
Release date:2004-03-30
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structural and energetic consequences of mutations in a solvated hydrophobic cavity.
J.Mol.Biol., 346, 2005
1T4Q
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1t4q
INTERLEUKIN 1 BETA F101W
Descriptor:Interleukin-1 beta
Authors:Adamek, D.H., Guerrero, L., Caspar, D.L.
Deposit date:2004-04-30
Release date:2004-12-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and energetic consequences of mutations in a solvated hydrophobic cavity.
J.Mol.Biol., 346, 2005
1TOO
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1too
INTERLEUKIN 1B MUTANT F146W
Descriptor:Interleukin-1 beta
Authors:Adamek, D.H., Guerrero, L., Caspar, D.L.
Deposit date:2004-06-14
Release date:2004-12-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and energetic consequences of mutations in a solvated hydrophobic cavity.
J.Mol.Biol., 346, 2005
1TP0
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1tp0
TRIPLE MUTATION IN INTERLEUKIN 1 BETA CAVITY:REPLACEMENT OF PHENYLALANINES WITH TRYPTOPHAN.
Descriptor:Interleukin-1 beta
Authors:Adamek, D.H., Guerrero, L., Caspar, D.L.
Deposit date:2004-06-15
Release date:2005-02-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and energetic consequences of mutations in a solvated hydrophobic cavity.
J.Mol.Biol., 346, 2005
1TWE
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1twe
INTERLEUKIN 1 BETA MUTANT F101Y
Descriptor:Interleukin-1 beta
Authors:Adamek, D.H., Capsar, D.L.
Deposit date:2004-06-30
Release date:2004-12-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and energetic consequences of mutations in a solvated hydrophobic cavity.
J.Mol.Biol., 346, 2005
1TWM
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1twm
INTERLEUKIN-1 BETA MUTANT F146Y
Descriptor:Interleukin-1 beta precursor
Authors:Adamek, D.H., Capsar, D.L.
Deposit date:2004-07-01
Release date:2004-12-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural and energetic consequences of mutations in a solvated hydrophobic cavity.
J.Mol.Biol., 346, 2005
21BI
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21bi
INTERLEUKIN-1 BETA (IL-1 BETA) (MUTANT WITH CYS 71 REPLACED BY ALA) (C71A)
Descriptor:INTERLEUKIN-1 BETA (IL-1 BETA) (MUTANT WITH CYS 71 REPLACED BY ALA) (C71A)
Authors:Veerapandian, B., Poulos, T.L., Gilliland, G.L., Masui, Y., Hirai, Y.
Deposit date:1991-03-21
Release date:1992-04-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:

2I1B
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2i1b
CRYSTALLOGRAPHIC REFINEMENT OF INTERLEUKIN-1 BETA AT 2.0 ANGSTROMS RESOLUTION
Descriptor:INTERLEUKIN-1 BETA (IL-1 BETA)
Authors:Priestle, J.P., Schaer, H.-P., Gruetter, M.G.
Deposit date:1990-01-02
Release date:1990-04-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic refinement of interleukin 1 beta at 2.0 A resolution.
Proc.Natl.Acad.Sci.USA, 86, 1989
2ILA
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2ila
STRUCTURE OF INTERLEUKIN 1ALPHA AT 2.7-ANGSTROMS RESOLUTION
Descriptor:INTERLEUKIN-1 ALPHA (IL-1 ALPHA)
Authors:Graves, B.J., Hatada, M.H.
Deposit date:1991-05-01
Release date:1992-10-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of interleukin 1 alpha at 2.7-A resolution.
Biochemistry, 29, 1990
2IRT
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2irt
INITIAL CRYSTALLOGRAPHIC ANALYSES OF A RECOMBINANT INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN
Descriptor:INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN
Authors:Finzel, B.C., Clancy, L.L., Einspahr, H.M.
Deposit date:1994-07-13
Release date:1994-10-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Initial crystallographic analysis of a recombinant human interleukin-1 receptor antagonist protein.
Acta Crystallogr.,Sect.D, 50, 1994
2KKI
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2kki
SOLUTION STRUCTURE OF HUMAN INTERLEUKIN 1A
Descriptor:Interleukin-1 alpha
Authors:Mohan, S.K., Chang, H.-K., Yu, C.
Deposit date:2009-06-24
Release date:2010-06-30
Method:SOLUTION NMR
Cite:1H, 13C and 15N backbone and side chain resonance assignments of human interleukin 1alpha
Biomol.Nmr Assign., 4, 2010
2MIB
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2mib
THE STRUCTURE OF MURINE INTERLEUKIN-1 BETA AT 2.8 ANGSTROMS RESOLUTION
Descriptor:INTERLEUKIN-1 BETA (IL-1 BETA)
Authors:Priestle, J.P., Van Oostrum, J., Schmitz, A., Gruetter, M.G.
Deposit date:1993-12-06
Release date:1994-01-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:The structure of murine interleukin-1 beta at 2.8 A resolution.
J.Struct.Biol., 107, 1991
2NVH
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2nvh
DETERMINATION OF SOLVENT CONTENT IN CAVITIES IN INTERLEUKIN-1 USING EXPERIMENTALLY-PHASED ELECTRON DENSITY
Descriptor:Interleukin-1 beta
Authors:Quillin, M.L., Matthews, B.W.
Deposit date:2006-11-12
Release date:2006-12-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Determination of solvent content in cavities in IL-1beta using experimentally phased electron density
Proc.Natl.Acad.Sci.Usa, 103, 2006
2WRY
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2wry
CRYSTAL STRUCTURE OF CHICKEN CYTOKINE INTERLEUKIN 1 BETA
Descriptor:INTERLEUKIN-1BETA
Authors:Lu, W.S., Cheng, C.S., Lyu, P.C., Lee, L.H., Wang, W.C., Yin, H.S.
Deposit date:2009-09-03
Release date:2010-09-29
Modification date:2011-04-06
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural and Functional Comparison of Cytokine Interleukin-1 Beta from Chicken and Human.
Mol.Immunol., 48, 2011
31BI
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31bi
INTERLEUKIN-1 BETA (IL-1 BETA) (MUTANT WITH CYS 71 REPLACED BY SER) (C71S)
Descriptor:INTERLEUKIN-1 BETA (IL-1 BETA) (MUTANT WITH CYS 71 REPLACED BY SER) (C71S)
Authors:Veerapandian, B., Poulos, T.L., Gilliland, G.L., Masui, Y., Hirai, Y.
Deposit date:1991-03-21
Release date:1992-04-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:

3LTQ
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3ltq
STRUCTURE OF INTERLEUKIN 1B SOLVED BY SAD USING AN INSERTED LANTHANIDE BINDING TAG
Descriptor:Interleukin-1 beta
Authors:Peisach, E., Allen, K.N.
Deposit date:2010-02-16
Release date:2011-02-16
Modification date:2011-03-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Engineering encodable lanthanide-binding tags into loop regions of proteins.
J.Am.Chem.Soc., 133, 2011
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