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1DFN
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1dfn
CRYSTAL STRUCTURE OF DEFENSIN HNP-3, AN AMPHIPHILIC DIMER: MECHANISMS OF MEMBRANE PERMEABILIZATION
Descriptor:DEFENSIN HNP-3
Authors:Hill, C.P., Yee, J., Selsted, M.E., Eisenberg, D.
Deposit date:1991-01-18
Release date:1992-07-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization.
Science, 251, 1991
1TV0
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1tv0
SOLUTION STRUCTURE OF CRYPTDIN-4, THE MOST POTENT ALPHA-DEFENSIN FROM MOUSE PANETH CELLS
Descriptor:Cryptdin-4
Authors:Jing, W., Hunter, H.N., Tanabe, H., Ouellette, A.J., Vogel, H.J.
Deposit date:2004-06-25
Release date:2005-01-04
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution Structure of Cryptdin-4, a Mouse Paneth Cell alpha-Defensin.
Biochemistry, 43, 2004
1ZMH
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1zmh
CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL PEPTIDE 2, HNP-2 (VARIANT GLY16-> D-ALA)
Descriptor:Neutrophil defensin 2
Authors:Lubkowski, J., Prahl, A., Lu, W.
Deposit date:2005-05-10
Release date:2005-08-16
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.
J.Biol.Chem., 280, 2005
1ZMI
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1zmi
CRYSTAL STRUCTURE OF HUMAN ALPHA_DEFENSIN-2 (VARIANT GLY16->D-ALA), P 32 2 1 SPACE GROUP )
Descriptor:Neutrophil defensin 2
Authors:Lubkowski, J., Prahl, A., Lu, W.
Deposit date:2005-05-10
Release date:2005-08-16
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.
J.Biol.Chem., 280, 2005
1ZMK
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1zmk
CRYSTAL STRUCTURE OF HUMAN ALPHA-DEFENSIN-2 (VARIANT GLY16-> D-ALA), P 42 21 2 SPACE GROUP
Descriptor:Neutrophil defensin 2
Authors:Lubkowski, J., Prahl, A., Lu, W.
Deposit date:2005-05-10
Release date:2005-08-16
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.
J.Biol.Chem., 280, 2005
1ZMM
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1zmm
CRYSTAL STRUCTURE OF HUMAN ALPHA-DEFENSIN-4
Descriptor:Neutrophil defensin 4
Authors:Lubkowski, J., Szyk, A., Lu, W.
Deposit date:2005-05-10
Release date:2006-05-30
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6.
Protein Sci., 15, 2006
1ZMP
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1zmp
CRYSTAL STRUCTURE OF HUMAN DEFENSIN-5
Descriptor:Defensin 5
Authors:Lubkowski, J., Szyk, A., Lu, W.
Deposit date:2005-05-10
Release date:2006-05-30
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6.
Protein Sci., 15, 2006
1ZMQ
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1zmq
CRYSTAL STRUCTURE OF HUMAN ALPHA-DEFENSIN-6
Descriptor:Defensin 6
Authors:Lubkowski, J., Szyk, A., Lu, W.
Deposit date:2005-05-10
Release date:2006-05-30
Modification date:2011-11-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6.
Protein Sci., 15, 2006
2GW9
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2gw9
HIGH-RESOLUTION SOLUTION STRUCTURE OF THE MOUSE DEFENSIN CRYPTDIN4
Descriptor:Defensin-related cryptdin 4
Authors:Rosengren, K.J., Craik, D.J., Vogel, H.J., Daly, N.L., Ouellette, A.J.
Deposit date:2006-05-04
Release date:2006-07-25
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins: solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4.
J.Biol.Chem., 281, 2006
2GWP
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2gwp
HIGH-RESOLUTION SOLUTION STRUCTURE OF THE SALT-BRIDGE DEFFICIENT MOUSE DEFENSIN (E15D)-CRYPTDIN4
Descriptor:Defensin-related cryptdin 4
Authors:Rosengren, K.J., Craik, D.J., Vogel, H.J., Daly, N.L., Ouellette, A.J.
Deposit date:2006-05-05
Release date:2006-07-25
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins: solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4.
J.Biol.Chem., 281, 2006
2K1I
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2k1i
SYNTHESIS, STRUCTURE AND ACTIVITIES OF AN ORAL MUCOSAL ALPHA-DEFENSIN FROM RHESUS MACAQUE
Descriptor:Mucosal Alpha-Defensin
Authors:Vasudevan, S.V., Yuan, J., Osapay, G., Tran,P, Tai, K., Selsted, M., Cocco, M.J.
Deposit date:2008-03-05
Release date:2008-10-28
Modification date:2013-06-19
Method:SOLUTION NMR
Cite:Synthesis, structure, and activities of an oral mucosal alpha-defensin from rhesus macaque.
J.Biol.Chem., 283, 2008
2KHT
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2kht
NMR STRUCTURE OF HUMAN ALPHA DEFENSIN HNP-1
Descriptor:Defensin, alpha 1
Authors:Zhang, Y., Li, S., Doherty, T.F., Lubkowski, J., Lu, W., Li, J., Barinka, C., Hong, M.
Deposit date:2009-04-11
Release date:2010-02-09
Modification date:2014-02-05
Method:SOLID-STATE NMR
Cite:Resonance assignment and three-dimensional structure determination of a human alpha-defensin, HNP-1, by solid-state NMR.
J.Mol.Biol., 397, 2010
2LXZ
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2lxz
SOLUTION STRUCTURE OF THE ANTIMICROBIAL PEPTIDE HUMAN DEFENSIN 5
Descriptor:Defensin-5
Authors:Wommack, A.J., Robson, S.A., Wanniarahchi, Y.A., Wan, A., Turner, C.J., Nolan, E.M.
Deposit date:2012-09-10
Release date:2012-11-28
Modification date:2013-02-20
Method:SOLUTION NMR
Cite:NMR solution structure and condition-dependent oligomerization of the antimicrobial Peptide human defensin 5.
Biochemistry, 51, 2012
2PM1
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2pm1
DERIVATIVE OF HUMAN ALPHA-DEFENSIN 1 (HNP1)
Descriptor:Neutrophil defensin 1 (HNP-1) (HP-1) (HP1) (Defensin, alpha 1)
Authors:Lubkowski, J., Pazgier, M., Lu, W.
Deposit date:2007-04-20
Release date:2007-05-29
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Derivative of human alpha-defensin 1 (HNP1)
To be Published
2PM4
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2pm4
HUMAN ALPHA-DEFENSIN 1 (MULTIPLE ARG->LYS MUTANT)
Descriptor:Neutrophil defensin 1 (HNP-1) (HP-1) (HP1) (Defensin, alpha 1)
Authors:Lubkowski, J., Pazgier, M., Lu, W.
Deposit date:2007-04-20
Release date:2007-05-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs.
J.Biol.Chem., 282, 2007
2PM5
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2pm5
HUMAN ALPHA-DEFENSIN 1 DERIVATIVE (HNP1)
Descriptor:Neutrophil defensin 1 (HNP-1) (HP-1) (HP1) (Defensin, alpha 1)
Authors:Lubkowski, J., Pazgier, M., Lu, W.
Deposit date:2007-04-20
Release date:2007-05-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Human alpha-defensin 1 derivative (HNP1)
To be Published
3GNY
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3gny
CRYSTAL STRUCTURE OF HUMAN ALPHA-DEFENSIN 1 (HNP1)
Descriptor:Neutrophil defensin 1
Authors:Pazgier, M., Lu, W-Y.
Deposit date:2009-03-18
Release date:2009-07-28
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Through the looking glass, mechanistic insights from enantiomeric human defensins.
J.Biol.Chem., 284, 2009
3H6C
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3h6c
CRYSTAL STRUCTURE OF HUMAN ALPHA-DEFENSIN 1 (MUTANT GLN22ALA)
Descriptor:Neutrophil defensin 1
Authors:Pazgier, M., Lu, W.
Deposit date:2009-04-23
Release date:2010-03-09
Modification date:2011-08-17
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
3HJ2
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3hj2
CRYSTAL STRUCTURE OF COVALENT DIMER OF HNP1
Descriptor:Neutrophil defensin 1
Authors:Lubkowski, J., Pazgier, M., Lu, W.
Deposit date:2009-05-20
Release date:2009-10-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:What Dictates the Multifaced Functions of the Human alpha-Defensin HNP1?
To be Published
3HJD
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3hjd
X-RAY STRUCTURE OF MONOMERIC VARIANT OF HNP1
Descriptor:Human neutrophil peptide 1
Authors:Lubkowski, J., Pazgier, M., Lu, W.
Deposit date:2009-05-21
Release date:2009-10-13
Modification date:2011-09-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:What Dictates the Multifaced Functions of the Human alpha-Defensin HNP?
To be Published
3I5W
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3i5w
CRYSTAL STRUCTURE OF HUMAN ALPHA-DEFENSIN 5 (MUTANT R13H)
Descriptor:Defensin-5
Authors:Pazgier, M., Lu, W.
Deposit date:2009-07-06
Release date:2009-07-28
Modification date:2012-04-11
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Selective arginines are important for the antibacterial activity and host cell interaction of human alpha-defensin 5
Febs Lett., 583, 2009
3LO1
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3lo1
CRYSTAL STRUCTURE OF HUMAN ALPHA-DEFENSIN 1 (Y16A MUTANT)
Descriptor:Neutrophil defensin 1
Authors:Pazgier, M., Lu, W.
Deposit date:2010-02-03
Release date:2010-03-09
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
3LO2
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3lo2
CRYSTAL STRUCTURE OF HUMAN ALPHA-DEFENSIN 1 (Y21A MUTANT)
Descriptor:Crystal structure of human alpha-defensin 1 (I6A mutant)
Authors:Pazgier, M., Lu, W.
Deposit date:2010-02-03
Release date:2010-03-09
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
3LO4
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3lo4
CRYSTAL STRUCTURE OF HUMAN ALPHA-DEFENSIN 1 (R24A MUTANT)
Descriptor:Neutrophil defensin 1
Authors:Pazgier, M., Lu, W.
Deposit date:2010-02-03
Release date:2010-03-09
Modification date:2011-08-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
3LO6
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3lo6
CRYSTAL STRUCTURE OF HUMAN ALPHA-DEFENSIN 1 (W26ABA MUTANT)
Descriptor:Neutrophil defensin 1
Authors:Pazgier, M., Lu, W.
Deposit date:2010-02-03
Release date:2010-03-09
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
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