3D3L
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THE 2.6 A CRYSTAL STRUCTURE OF THE LIPOXYGENASE DOMAIN OF HUMAN ARACHIDONATE 12-LIPOXYGENASE, 12S-TYPE (CASP TARGET)
Descriptor:Arachidonate 12-lipoxygenase, 12S-type (E.C.1.13.11.31)
Authors:Tresaugues, L., Moche, M., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Schueler, H., Svensson, L., Thorsell, A.G., Van Den Berg, S., Welin, M., Weigelt, J., Wikstrom, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2008-05-12
Release date:2008-09-09
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the lipoxygenase domain of human Arachidonate 12-lipoxygenase, 12S-type.
To be Published
3RDE
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PORCINE LEUKOCYTE 12-LIPOXYGENASE
Descriptor:Arachidonate 12-lipoxygenase, 12S-type (E.C.1.13.11.31)
Authors:Funk, M.O., Xu, S., Marnett, L.J., Mueser, T.C.
Deposit date:2011-04-01
Release date:2012-04-18
Modification date:2012-09-26
Method:X-RAY DIFFRACTION (1.892 Å)
Cite:Crystal structure of 12-lipoxygenase catalytic-domain-inhibitor complex identifies a substrate-binding channel for catalysis.
Structure, 20, 2012
5EK8
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CRYSTAL STRUCTURE OF A 9R-LIPOXYGENASE FROM CYANOTHECE PCC8801 AT 2.7 ANGSTROMS
Descriptor:Lipoxygenase
Authors:Feussner, I., Ficner, R., Neumann, P., Newie, J., Andreou, A., Einsle, O.
Deposit date:2015-11-03
Release date:2015-12-23
Modification date:2016-02-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a lipoxygenase from Cyanothece sp. may reveal novel features for substrate acquisition.
J.Lipid Res., 57, 2016
5FNO
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MANGANESE LIPOXYGENASE
Descriptor:MANGANESE LIPOXYGENASE (E.C.1.13.11.45)
Authors:Wennman, A., Karkehabadi, S., Oliw, E.H., Chen, Y.
Deposit date:2015-11-16
Release date:2016-01-27
Method:X-RAY DIFFRACTION (2.038 Å)
Cite:Crystal Structure of Manganese Lipoxygenase of the Rice Blast Fungus Magnaporthe Oryzae
J.Biol.Chem., 2016
1F8N
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LIPOXYGENASE-1 (SOYBEAN) AT 100K, NEW REFINEMENT
Descriptor:LIPOXYGENASE-1 (E.C. 1.13.11.12)
Authors:Tomchick, D.R., Minor, W., Holman, T.
Deposit date:2000-06-30
Release date:2001-07-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGM
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LIPOXYGENASE-1 (SOYBEAN) AT 100K, N694H MUTANT
Descriptor:LIPOXYGENASE-1 (E.C.1.13.11.12)
Authors:Tomchick, D.R., Minor, W., Holman, T.R.
Deposit date:2000-07-28
Release date:2001-10-24
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGO
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LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q495A MUTANT
Descriptor:LIPOXYGENASE-1 (E.C.1.13.11.12)
Authors:Tomchick, D.R., Minor, W., Holman, T.
Deposit date:2000-07-28
Release date:2001-07-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGQ
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LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q495E MUTANT
Descriptor:LIPOXYGENASE-1 (E.C.1.13.11.12)
Authors:Tomchick, D.R., Minor, W., Holman, T.
Deposit date:2000-07-28
Release date:2001-07-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGR
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LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q697E MUTANT
Descriptor:LIPOXYGENASE-1 (E.C.1.13.11.12)
Authors:Tomchick, D.R., Minor, W., Holman, T.
Deposit date:2000-07-28
Release date:2001-07-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGT
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LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q697N MUTANT
Descriptor:LIPOXYGENASE-1 (E.C.1.13.11.12)
Authors:Tomchick, D.R., Minor, W., Holman, T.
Deposit date:2000-07-28
Release date:2001-07-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1HU9
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LIPOXYGENASE-3 (SOYBEAN) COMPLEX WITH 4-HYDROPEROXY-2-METHOXY-PHENOL
Descriptor:LIPOXYGENASE-3
Authors:Zhou, K., Skrzypczak-Jankun, E., McCabe, N.P., Selman, S.H., Jankun, J.
Deposit date:2001-01-04
Release date:2003-06-03
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of curcumin in complex with lipoxygenase and its significance in cancer.
INT.J.MOL.MED., 12, 2003
1IK3
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LIPOXYGENASE-3 (SOYBEAN) COMPLEX WITH 13(S)-HYDROPEROXY-9(Z),11(E)-OCTADECADIENOIC ACID
Descriptor:LIPOXYGENASE-3 (E.C.1.13.11.12)
Authors:Skrzypczak-Jankun, E., Funk Jr., M.O.
Deposit date:2001-05-01
Release date:2001-11-14
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of a purple lipoxygenase.
J.Am.Chem.Soc., 123, 2001
1JNQ
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LIPOXYGENASE-3 (SOYBEAN) COMPLEX WITH EPIGALLOCATHECHIN (EGC)
Descriptor:LIPOXYGENASE-3
Authors:Zhou, K., Skrzypczak-Jankun, E., Jankun, J.
Deposit date:2001-07-24
Release date:2003-06-03
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inhibition of lipoxygenase by (-)-epigallocatechin gallate: X-ray analysis at 2.1 A reveals degradation of EGCG and shows soybean LOX-3 complex with EGC instead.
INT.J.MOL.MED., 12, 2003
1LNH
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LIPOXYGENASE-3(SOYBEAN) NON-HEME FE(II) METALLOPROTEIN
Descriptor:LIPOXYGENASE-3
Authors:Skrzypczak-Jankun, E.
Deposit date:1996-03-29
Release date:1997-02-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of soybean lipoxygenase L3 and a comparison with its L1 isoenzyme.
Proteins, 29, 1997
1LOX
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RABBIT RETICULOCYTE 15-LIPOXYGENASE
Descriptor:15-LIPOXYGENASE, 3-(2-OCTYLPHENYL)PROPANOIC ACID
Authors:Gillmor, S.A., Villasenor, A., Fletterick, R.J., Sigal, E., Browner, M.F.
Deposit date:1997-10-06
Release date:1998-11-04
Modification date:2015-12-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity.
Nat.Struct.Biol., 4, 1997
1N8Q
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LIPOXYGENASE IN COMPLEX WITH PROTOCATECHUIC ACID
Descriptor:LIPOXYGENASE-3 (E.C.1.13.11.12)
Authors:Borbulevych, O.Y., Jankun, J., Selman, S.H., Skrzypczak-Jankun, E.
Deposit date:2002-11-21
Release date:2003-06-03
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Lipoxygenase interactions with natural flavonoid, quercetin, reveal a complex with protocatechuic acid in its X-ray structure at 2.1 A resolution.
PROTEINS: STRUCT.,FUNCT.,GENET., 54, 2004
1NO3
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REFINED STRUCTURE OF SOYBEAN LIPOXYGENASE-3 WITH 4-NITROCATECHOL AT 2.15 ANGSTROM RESOLUTION
Descriptor:LIPOXYGENASE-3 (E.C.1.13.11.12)
Authors:Skrzypczak-Jankun, E., Borbulevych, O.Y., Jankun, J.
Deposit date:2003-01-15
Release date:2003-06-03
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Soybean lipoxygenase-3 in complex with 4-nitrocatechol.
Acta Crystallogr.,Sect.D, 60, 2004
1ROV
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LIPOXYGENASE-3 TREATED WITH CUMENE HYDROPEROXIDE
Descriptor:Seed lipoxygenase-3 (E.C.1.13.11.12)
Authors:Vahedi-Faridi, A., Brault, P.A., Shah, P., Kim, Y.W., Dunham, W.R., Funk, M.O.
Deposit date:2003-12-02
Release date:2004-03-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interaction between non-heme iron of lipoxygenases and cumene hydroperoxide: basis for enzyme activation, inactivation, and inhibition
J.Am.Chem.Soc., 126, 2004
1RRH
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SOYBEAN LIPOXYGENASE (LOX-3) AT AMBIENT TEMPERATURES AT 2.0 A RESOLUTION
Descriptor:Seed lipoxygenase-3 (E.C.1.13.11.12)
Authors:Borbulevych, O.Y., Jankun, J., Skrzypczak-Jankun, E.
Deposit date:2003-12-08
Release date:2004-12-21
Modification date:2012-02-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effect of crystal freezing and small-molecule binding on internal cavity size in a large protein: X-ray and docking studies of lipoxygenase at ambient and low temperature at 2.0 A resolution.
Acta Crystallogr.,Sect.D, 62, 2006
1RRL
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SOYBEAN LIPOXYGENASE (LOX-3) AT 93K AT 2.0 A RESOLUTION
Descriptor:Seed lipoxygenase-3 (E.C.1.13.11.12)
Authors:Borbulevych, O.Y., Jankun, J., Skrzypczak-Jankun, E.
Deposit date:2003-12-08
Release date:2004-12-21
Modification date:2012-02-08
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Effect of crystal freezing and small-molecule binding on internal cavity size in a large protein: X-ray and docking studies of lipoxygenase at ambient and low temperature at 2.0 A resolution.
Acta Crystallogr.,Sect.D, 62, 2006
1Y4K
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LIPOXYGENASE-1 (SOYBEAN) AT 100K, N694G MUTANT
Descriptor:Seed lipoxygenase-1 (E.C.1.13.11.12)
Authors:Chruszcz, M., Segraves, E., Holman, T.R., Minor, W.
Deposit date:2004-12-01
Release date:2005-12-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Kinetic, spectroscopic, and structural investigations of the soybean lipoxygenase-1 first-coordination sphere mutant, Asn694Gly.
Biochemistry, 45, 2006
1YGE
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LIPOXYGENASE-1 (SOYBEAN) AT 100K
Descriptor:LIPOXYGENASE-1
Authors:Minor, W., Steczko, J., Stec, B., Otwinowski, Z., Bolin, J.T., Walter, R., Axelrod, B.
Deposit date:1996-06-04
Release date:1997-07-23
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution.
Biochemistry, 35, 1996
2IUK
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CRYSTAL STRUCTURE OF SOYBEAN LIPOXYGENASE-D
Descriptor:SEED LIPOXYGENASE (E.C.1.13.11.12)
Authors:Youn, B., Sellhorn, G.E., Mirchel, R.J., Gaffney, B.J., Grimes, H.D., Kang, C.
Deposit date:2006-06-05
Release date:2006-10-11
Modification date:2011-12-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Vegetative Soybean Lipoxygenase Vlx-B and Vlx-D, and Comparisons with Seed Isoforms Lox-1 and Lox-3.
Proteins, 65, 2006
2P0M
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REVISED STRUCTURE OF RABBIT RETICULOCYTE 15S-LIPOXYGENASE
Descriptor:Arachidonate 15-lipoxygenase (E.C.1.13.11.33)
Authors:Choi, J., Chon, J.K., Kim, S., Shin, W.
Deposit date:2007-02-28
Release date:2007-10-09
Modification date:2011-09-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformational flexibility in mammalian 15S-lipoxygenase: Reinterpretation of the crystallographic data.
Proteins, 70, 2008
2SBL
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THE THREE-DIMENSIONAL STRUCTURE OF AN ARACHIDONIC ACID 15-LIPOXYGENASE
Descriptor:LIPOXYGENASE-1 (SOYBEAN) (E.C.1.13.11.12)
Authors:Amzel, L.M., Boyington, J.C.
Deposit date:1993-07-22
Release date:1995-02-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The three-dimensional structure of an arachidonic acid 15-lipoxygenase.
Science, 260, 1993
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