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1BNC
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BU of 1bnc by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE BIOTIN CARBOXYLASE SUBUNIT OF ACETYL-COA CARBOXYLASE
Descriptor: BIOTIN CARBOXYLASE, PHOSPHATE ION
Authors:Waldrop, G, Rayment, I, Holden, H.M.
Deposit date:1994-07-06
Release date:1995-08-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structure of the biotin carboxylase subunit of acetyl-CoA carboxylase.
Biochemistry, 33, 1994
1DV2
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BU of 1dv2 by Molmil
The structure of biotin carboxylase, mutant E288K, complexed with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, BIOTIN CARBOXYLASE
Authors:Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L.
Deposit date:2000-01-19
Release date:2000-06-09
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Movement of the biotin carboxylase B-domain as a result of ATP binding.
J.Biol.Chem., 275, 2000
1DV1
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BU of 1dv1 by Molmil
STRUCTURE OF BIOTIN CARBOXYLASE (APO)
Descriptor: BIOTIN CARBOXYLASE, PHOSPHATE ION
Authors:Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L.
Deposit date:2000-01-19
Release date:2000-06-09
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Movement of the biotin carboxylase B-domain as a result of ATP binding.
J.Biol.Chem., 275, 2000
1ULZ
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BU of 1ulz by Molmil
Crystal structure of the biotin carboxylase subunit of pyruvate carboxylase
Descriptor: pyruvate carboxylase n-terminal domain
Authors:Kondo, S, Nakajima, Y, Sugio, S, Yong-Biao, J, Sueda, S, Kondo, H.
Deposit date:2003-09-18
Release date:2004-03-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the biotin carboxylase subunit of pyruvate carboxylase from Aquifex aeolicus at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 60, 2004
1W93
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BU of 1w93 by Molmil
Crystal Structure of Biotin Carboxylase Domain of Acetyl-Coenzyme A Carboxylase from Saccharomyces cerevisiae
Descriptor: ACETYL-COENZYME A CARBOXYLASE
Authors:Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L.
Deposit date:2004-10-05
Release date:2005-01-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product
Mol.Cell, 16, 2004
1W96
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BU of 1w96 by Molmil
Crystal Structure of Biotin Carboxylase Domain of Acetyl-coenzyme A Carboxylase from Saccharomyces cerevisiae in Complex with Soraphen A
Descriptor: ACETYL-COENZYME A CARBOXYLASE, SORAPHEN A
Authors:Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L.
Deposit date:2004-10-06
Release date:2005-01-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product
Mol.Cell, 16, 2004
2GPW
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BU of 2gpw by Molmil
Crystal Structure of the Biotin Carboxylase Subunit, F363A Mutant, of Acetyl-CoA Carboxylase from Escherichia coli.
Descriptor: Biotin carboxylase
Authors:Shen, Y, Chou, C.Y, Chang, G.G, Tong, L.
Deposit date:2006-04-18
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Is dimerization required for the catalytic activity of bacterial biotin carboxylase?
Mol.Cell, 22, 2006
2GPS
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BU of 2gps by Molmil
Crystal Structure of the Biotin Carboxylase Subunit, E23R mutant, of Acetyl-CoA Carboxylase from Escherichia coli.
Descriptor: Biotin carboxylase
Authors:Shen, Y, Chou, C.Y, Chang, G.G, Tong, L.
Deposit date:2006-04-18
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Is dimerization required for the catalytic activity of bacterial biotin carboxylase?
Mol.Cell, 22, 2006
2HJW
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BU of 2hjw by Molmil
Crystal Structure of the BC domain of ACC2
Descriptor: Acetyl-CoA carboxylase 2
Authors:Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S.
Deposit date:2006-07-02
Release date:2007-07-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2.
Proteins, 70, 2008
2QF7
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BU of 2qf7 by Molmil
Crystal structure of a complete multifunctional pyruvate carboxylase from Rhizobium etli
Descriptor: CHLORIDE ION, COENZYME A, FORMIC ACID, ...
Authors:St Maurice, M, Surinya, K.H, Rayment, I.
Deposit date:2007-06-27
Release date:2007-09-04
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme
Science, 317, 2007
2DZD
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BU of 2dzd by Molmil
Crystal structure of the biotin carboxylase domain of pyruvate carboxylase
Descriptor: pyruvate carboxylase
Authors:Kondo, S, Nakajima, Y, Sugio, S, Sueda, S, Islam, M.N, Kondo, H.
Deposit date:2006-09-27
Release date:2007-09-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the biotin carboxylase domain of pyruvate carboxylase from Bacillus thermodenitrificans
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
3BG5
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BU of 3bg5 by Molmil
Crystal Structure of Staphylococcus Aureus Pyruvate Carboxylase
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Xiang, S, Tong, L.
Deposit date:2007-11-26
Release date:2008-02-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction.
Nat.Struct.Mol.Biol., 15, 2008
2VQD
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BU of 2vqd by Molmil
Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa complexed with AMPCP
Descriptor: BIOTIN CARBOXYLASE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
Authors:Mochalkin, I.
Deposit date:2008-03-13
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
2VPQ
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BU of 2vpq by Molmil
Crystal structure of biotin carboxylase from S. aureus complexed with AMPPNP
Descriptor: ACETYL-COA CARBOXYLASE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Mochalkin, I.
Deposit date:2008-03-03
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
2C00
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BU of 2c00 by Molmil
Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa in apo form
Descriptor: BIOTIN CARBOXYLASE, SULFATE ION
Authors:Mochalkin, I.
Deposit date:2008-03-21
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
2J9G
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BU of 2j9g by Molmil
Crystal structure of Biotin carboxylase from E. coli in complex with AMPPNP and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BIOTIN CARBOXYLASE, MAGNESIUM ION, ...
Authors:Mochalkin, I.
Deposit date:2008-03-21
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
2VR1
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BU of 2vr1 by Molmil
Crystal structure of Biotin carboxylase from E. coli in complex with ATP analog, ADPCF2P.
Descriptor: BIOTIN CARBOXYLASE, CHLORIDE ION, PHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Mochalkin, I, Waldrop, G.L.
Deposit date:2008-03-24
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
2V59
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BU of 2v59 by Molmil
CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 2
Descriptor: 6-(2,6-DIMETHOXYPHENYL)PYRIDO[2,3-D]PYRIMIDINE-2,7-DIAMINE, BIOTIN CARBOXYLASE
Authors:Mochalkin, I, Miller, J.R.
Deposit date:2008-10-02
Release date:2009-01-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore.
Proc.Natl.Acad.Sci.USA, 106, 2009
2V58
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BU of 2v58 by Molmil
CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 1
Descriptor: 6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine, BIOTIN CARBOXYLASE, CHLORIDE ION
Authors:Mochalkin, I, Miller, J.R.
Deposit date:2008-10-02
Release date:2009-01-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore.
Proc.Natl.Acad.Sci.USA, 106, 2009
2V5A
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BU of 2v5a by Molmil
CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 3
Descriptor: 7-(2,5-dihydropyrrol-1-yl)-6-phenyl-pyrido[6,5-d]pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION
Authors:Mochalkin, I, Miller, J.R.
Deposit date:2008-10-02
Release date:2009-01-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore.
Proc.Natl.Acad.Sci.USA, 106, 2009
3G8C
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BU of 3g8c by Molmil
Crystal Structure of Biotin Carboxylase in Complex with Biotin, Bicarbonate, ADP and Mg Ion
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, BIOTIN, ...
Authors:Chou, C.Y, Yu, L.P, Tong, L.
Deposit date:2009-02-12
Release date:2009-03-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism.
J.Biol.Chem., 284, 2009
3G8D
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BU of 3g8d by Molmil
Crystal structure of the biotin carboxylase subunit, E296A mutant, of acetyl-COA carboxylase from Escherichia coli
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, MAGNESIUM ION, ...
Authors:Chou, C.Y, Yu, L.P, Tong, L.
Deposit date:2009-02-12
Release date:2009-03-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism.
J.Biol.Chem., 284, 2009
3GID
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BU of 3gid by Molmil
The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2) in complex with Soraphen A
Descriptor: Acetyl-CoA carboxylase 2, SORAPHEN A
Authors:Price, A, Kulathila, R.
Deposit date:2009-03-05
Release date:2009-03-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Synthesis and characterization of a BODIPY-labeled derivative of Soraphen A that binds to acetyl-CoA carboxylase.
Bioorg.Med.Chem.Lett., 19, 2009
3GLK
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BU of 3glk by Molmil
The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2)
Descriptor: Acetyl-CoA carboxylase 2
Authors:Price, A, Kulathila, R.
Deposit date:2009-03-12
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Synthesis and characterization of a BODIPY-labeled derivative of Soraphen A that binds to acetyl-CoA carboxylase.
Bioorg.Med.Chem.Lett., 19, 2009
2W6O
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Crystal structure of Biotin carboxylase from E. coli in complex with 4-Amino-7,7-dimethyl-7,8-dihydro-quinazolinone fragment
Descriptor: 4-amino-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one, BIOTIN CARBOXYLASE, CHLORIDE ION
Authors:Mochalkin, I, Miller, J.R.
Deposit date:2008-12-18
Release date:2009-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches.
Acs Chem.Biol., 4, 2009

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