8HPI
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8B74
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7XIO
| Crystal structure of TYR from Ralstonia | Descriptor: | PHOSPHATE ION, Polyphenol oxidase | Authors: | Sun, D.Y, Cui, P.P, Liao, L.J, Liu, X.K, Liu, B, Guo, Y, Feng, Z, Zhang, J, Li, X, Zeng, Z.X. | Deposit date: | 2022-04-13 | Release date: | 2023-04-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Crystal structure of TYR from Ralstonia To Be Published
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7CIY
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7CIT
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6Z1S
| Structure of Polyphenol Oxidase (mutant G292N) from Thermothelomyces thermophila | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Dimarogona, M, Nikolaivits, E, Valmas, A, Topakas, E. | Deposit date: | 2020-05-14 | Release date: | 2021-03-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Considerations Regarding Activity Determinants of Fungal Polyphenol Oxidases Based on Mutational and Structural Studies. Appl.Environ.Microbiol., 87, 2021
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6R83
| CryoEM structure and molecular model of squid hemocyanin (Todarodes pacificus , TpH) | Descriptor: | Hemocyanin subunit 1 | Authors: | Tanaka, Y, Kato, S, Stabrin, M, Raunser, S, Matsui, T, Gatsogiannis, C. | Deposit date: | 2019-03-31 | Release date: | 2019-05-08 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Cryo-EM reveals the asymmetric assembly of squid hemocyanin. Iucrj, 6, 2019
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6QXD
| Crystal Structure of tyrosinase from Bacillus megaterium with JKB inhibitor in the active site. | Descriptor: | (2,4-dinitrophenyl)-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]methanone, COPPER (II) ION, Tyrosinase | Authors: | Deri Zenaty, B, Gitto, R, Pazy, Y, Fishman, A. | Deposit date: | 2019-03-07 | Release date: | 2019-06-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.317 Å) | Cite: | Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile. Eur.J.Med.Chem., 178, 2019
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6JUD
| Radiation damage in Aspergillus oryzae pro-tyrosinase oxygen-bound C92A/H103F mutant | Descriptor: | COPPER (II) ION, PEROXIDE ION, Tyrosinase | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | Deposit date: | 2019-04-13 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism. Angew.Chem.Int.Ed.Engl., 59, 2020
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6JUC
| Aspergillus oryzae pro-tyrosinase oxygen-bound C92A/H103F mutant | Descriptor: | COPPER (II) ION, PEROXIDE ION, Tyrosinase | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | Deposit date: | 2019-04-13 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism. Angew.Chem.Int.Ed.Engl., 59, 2020
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6JUB
| Radiation damage in Aspergillus oryzae pro-tyrosinase oxygen-bound C92A mutant | Descriptor: | COPPER (II) ION, PEROXIDE ION, Tyrosinase | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | Deposit date: | 2019-04-13 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism. Angew.Chem.Int.Ed.Engl., 59, 2020
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6JUA
| Aspergillus oryzae pro-tyrosinase oxygen-bound C92A mutant | Descriptor: | COPPER (II) ION, PEROXIDE ION, Tyrosinase | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | Deposit date: | 2019-04-13 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism. Angew.Chem.Int.Ed.Engl., 59, 2020
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6JU9
| Aspergillus oryzae active-tyrosinase copper-bound C92A mutant complexed with L-tyrosine | Descriptor: | 3,4-DIHYDROXYPHENYLALANINE, COPPER (II) ION, NITRATE ION, ... | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | Deposit date: | 2019-04-13 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism. Angew.Chem.Int.Ed.Engl., 59, 2020
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6JU8
| Aspergillus oryzae active-tyrosinase copper-bound C92A mutant | Descriptor: | COPPER (II) ION, NITRATE ION, Tyrosinase | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | Deposit date: | 2019-04-13 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism. Angew.Chem.Int.Ed.Engl., 59, 2020
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6JU7
| Aspergillus oryzae active-tyrosinase copper-depleted C92A mutant complexed with L-tyrosine | Descriptor: | NITRATE ION, TYROSINE, Tyrosinase | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | Deposit date: | 2019-04-13 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism. Angew.Chem.Int.Ed.Engl., 59, 2020
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6JU6
| Aspergillus oryzae active-tyrosinase copper-depleted C92A mutant | Descriptor: | NITRATE ION, Tyrosinase | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | Deposit date: | 2019-04-13 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism. Angew.Chem.Int.Ed.Engl., 59, 2020
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6JU5
| Aspergillus oryzae pro-tyrosinase C92A/F513Y mutant | Descriptor: | COPPER (II) ION, Tyrosinase | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | Deposit date: | 2019-04-13 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism. Angew.Chem.Int.Ed.Engl., 59, 2020
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6JU4
| Aspergillus oryzae pro-tyrosinase F513Y mutant | Descriptor: | COPPER (II) ION, Tyrosinase | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | Deposit date: | 2019-04-13 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism. Angew.Chem.Int.Ed.Engl., 59, 2020
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6J2U
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6HQJ
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6HQI
| holo-form of polyphenol oxidase from Solanum lycopersicum | Descriptor: | COPPER (II) ION, OXYGEN ATOM, Polyphenol oxidase A, ... | Authors: | Kampatsikas, I, Bijelic, A, Rompel, A. | Deposit date: | 2018-09-25 | Release date: | 2019-03-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Biochemical and structural characterization of tomato polyphenol oxidases provide novel insights into their substrate specificity. Sci Rep, 9, 2019
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6GSG
| Crystal structure of Aspergillus oryzae catechol oxidase complexed with resorcinol | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, Catechol oxidase, ... | Authors: | Penttinen, L, Hakulinen, N, Rouvinen, J. | Deposit date: | 2018-06-14 | Release date: | 2018-09-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.192 Å) | Cite: | Unraveling Substrate Specificity and Catalytic Promiscuity of Aspergillus oryzae Catechol Oxidase. Chembiochem, 19, 2018
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6ELS
| Structure of latent apple tyrosinase (MdPPO1) | Descriptor: | COPPER (II) ION, OXYGEN ATOM, Polyphenol oxidase, ... | Authors: | Kampatsikas, I, Bijelic, A, Pretzler, M, Rompel, A. | Deposit date: | 2017-09-29 | Release date: | 2019-03-20 | Last modified: | 2019-05-29 | Method: | X-RAY DIFFRACTION (1.346 Å) | Cite: | A Peptide-Induced Self-Cleavage Reaction Initiates the Activation of Tyrosinase. Angew.Chem.Int.Ed.Engl., 58, 2019
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6EI4
| Crystal Structure of tyrosinase from Bacillus megaterium with B5N inhibitor in the active site | Descriptor: | COPPER (II) ION, Tyrosinase, [4-[(4-fluorophenyl)methyl]piperazin-1-yl]-(2-methylphenyl)methanone | Authors: | Deri, B, Gitto, R, Pazy Benhar, Y, Fishman, A. | Deposit date: | 2017-09-17 | Release date: | 2018-04-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments. J. Med. Chem., 61, 2018
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5ZRE
| Tyrosinase from Burkholderia thailandensis (BtTYR) at high pH condition | Descriptor: | COPPER (II) ION, GLYCEROL, OXYGEN ATOM, ... | Authors: | Lee, S, Son, H.-F, Kim, K.-J. | Deposit date: | 2018-04-24 | Release date: | 2018-10-31 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Highly Efficient Production of Catechol Derivatives at Acidic pH by Tyrosinase from Burkholderia thailandensis Acs Catalysis, 8, 2018
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