5JTW
  • Download 5jtw
  • View 5jtw
Molmil generated image of 5jtw
CRYSTAL STRUCTURE OF COMPLEMENT C4B RE-REFINED USING IMDFF
Descriptor:Complement C4-A
Authors:Croll, T.I., Andersen, G.R.
Deposit date:2016-05-09
Release date:2016-08-10
Modification date:2016-09-28
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Re-evaluation of low-resolution crystal structures via interactive molecular-dynamics flexible fitting (iMDFF): a case study in complement C4.
Acta Crystallogr D Struct Biol, 72, 2016
5JPM
  • Download 5jpm
  • View 5jpm
Molmil generated image of 5jpm
STRUCTURE OF THE COMPLEX OF HUMAN COMPLEMENT C4 WITH MASP-2 REBUILT USING IMDFF
Descriptor:Complement C4-A, Mannan-binding lectin serine protease 2 (E.C.3.4.21.104)
Authors:Croll, T.I., Andersen, G.R.
Deposit date:2016-05-03
Release date:2016-08-10
Modification date:2016-09-28
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Re-evaluation of low-resolution crystal structures via interactive molecular-dynamics flexible fitting (iMDFF): a case study in complement C4.
Acta Crystallogr D Struct Biol, 72, 2016
5JPN
  • Download 5jpn
  • View 5jpn
Molmil generated image of 5jpn
STRUCTURE OF HUMAN COMPLEMENT C4 REBUILT USING IMDFF
Descriptor:Complement C4-A
Authors:Croll, T.I., Andersen, G.R.
Deposit date:2016-05-03
Release date:2016-08-10
Modification date:2016-09-28
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Re-evaluation of low-resolution crystal structures via interactive molecular-dynamics flexible fitting (iMDFF): a case study in complement C4.
Acta Crystallogr D Struct Biol, 72, 2016
5I5K
  • Download 5i5k
  • View 5i5k
Molmil generated image of 5i5k
STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH ECULIZUMAB
Descriptor:Complement C5, Eculizumab heavy chain (variable domain), Eculizumab light chain (variable domain)
Authors:Schatz-Jakobsen, J.A., Andersen, G.R.
Deposit date:2016-02-15
Release date:2016-03-16
Modification date:2016-06-29
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structural Basis for Eculizumab-Mediated Inhibition of the Complement Terminal Pathway.
J Immunol., 197, 2016
5HCC
  • Download 5hcc
  • View 5hcc
Molmil generated image of 5hcc
TERNARY COMPLEX OF HUMAN COMPLEMENT C5 WITH ORNITHODOROS MOUBATA OMCI AND DERMACENTOR ANDERSONI RACI3.
Descriptor:Complement C5, Complement inhibitor, Dermacentor andersoni RaCI3
Authors:Jore, M.M., Johnson, S., Lea, S.M.
Deposit date:2016-01-04
Release date:2016-03-30
Modification date:2016-05-11
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural basis for therapeutic inhibition of complement C5.
Nat.Struct.Mol.Biol., 23, 2016
5HCD
  • Download 5hcd
  • View 5hcd
Molmil generated image of 5hcd
TERNARY COMPLEX OF HUMAN COMPLEMENT C5 WITH ORNITHODOROS MOUBATA OMCI AND RHIPICEPHALUS MICROPLUS RACI2
Descriptor:Complement C5, Complement inhibitor, Rhipicephalus microplus RaCI2
Authors:Jore, M.M., Johnson, S., Lea, S.M.
Deposit date:2016-01-04
Release date:2016-03-30
Modification date:2016-05-11
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Structural basis for therapeutic inhibition of complement C5.
Nat.Struct.Mol.Biol., 23, 2016
5HCE
  • Download 5hce
  • View 5hce
Molmil generated image of 5hce
TERNARY COMPLEX OF HUMAN COMPLEMENT C5 WITH ORNITHODOROS MOUBATA OMCI AND RHIPICEPHALUS APPENDICULATUS RACI1
Descriptor:Complement C5, Complement inhibitor, Rhipicephalus appendiculatus RaCI1
Authors:Jore, M.M., Johnson, S., Lea, S.M.
Deposit date:2016-01-04
Release date:2016-03-30
Modification date:2016-05-18
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Structural basis for therapeutic inhibition of complement C5.
Nat.Struct.Mol.Biol., 23, 2016
5FO7
  • Download 5fo7
  • View 5fo7
Molmil generated image of 5fo7
CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B AT 2.8 ANGSTROM RESOLUTION
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Modification date:2016-06-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FO8
  • Download 5fo8
  • View 5fo8
Molmil generated image of 5fo8
CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH MCP (CCP1-4)
Descriptor:COMPLEMENT C3 (E.C.3.4.21.47), MEMBRANE COFACTOR PROTEIN
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Modification date:2016-06-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FO9
  • Download 5fo9
  • View 5fo9
Molmil generated image of 5fo9
CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH CR1 (CCP15- 17)
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, COMPLEMENT RECEPTOR TYPE 1
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Modification date:2016-06-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FOA
  • Download 5foa
  • View 5foa
Molmil generated image of 5foa
CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH DAF (CCP2-4)
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA CHAIN, DECAY ACCELERATING FACTOR, CD55
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Modification date:2016-06-01
Method:X-RAY DIFFRACTION (4.188 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5FOB
  • Download 5fob
  • View 5fob
Molmil generated image of 5fob
CRYSTAL STRUCTURE OF HUMAN COMPLEMENT C3B IN COMPLEX WITH SMALLPOX INHIBITOR OF COMPLEMENT (SPICE)
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, SMALLPOX INHIBITOR OF COMPLEMENT SPICE, D15L
Authors:Forneris, F., Wu, J., Xue, X., Gros, P.
Deposit date:2015-11-18
Release date:2016-04-06
Modification date:2016-06-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5A42
  • Download 5a42
  • View 5a42
Molmil generated image of 5a42
CRYO-EM SINGLE PARTICLE 3D RECONSTRUCTION OF THE NATIVE CONFORMATION OF E. COLI ALPHA-2-MACROGLOBULIN (ECAM)
Descriptor:UNCHARACTERIZED LIPOPROTEIN YFHM
Authors:Garcia-Ferrer, I., Arede, P., Gomez-Blanco, J., Luque, D., Duquerroy, S., Caston, J.R., Goulas, T., Gomis-Ruth, F.X.
Deposit date:2015-06-04
Release date:2015-07-29
Modification date:2015-08-19
Method:ELECTRON MICROSCOPY (16 Å)
Cite:Structural and Functional Insights Into Escherichia Coli Alpha2- Macroglobulin Endopeptidase Snap-Trap Inhibition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZIQ
  • Download 4ziq
  • View 4ziq
Molmil generated image of 4ziq
CRYSTAL STRUCTURE OF TRYPSIN ACTIVATED ALPHA-2-MACROGLOBULIN FROM ESCHERICHIA COLI.
Descriptor:alpha-2-Macroglobulin
Authors:Garcia-Ferrer, I., Arede, P., Gomez-Blanco, J., Luque, D., Duquerroy, S., Caston, J.R., Goulas, T., Gomis-Ruth, X.F.
Deposit date:2015-04-28
Release date:2015-06-10
Modification date:2015-07-15
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural and functional insights into Escherichia coli alpha 2-macroglobulin endopeptidase snap-trap inhibition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZIU
  • Download 4ziu
  • View 4ziu
Molmil generated image of 4ziu
CRYSTAL STRUCTURE OF NATIVE ALPHA-2-MACROGLOBULIN FROM ESCHERICHIA COLI SPANNING THE RESIDUES FROM DOMAIN MG7 TO THE C-TERMINUS.
Descriptor:alpha-2-Macroglobulin
Authors:Garcia-Ferrer, I., Arede, P., Gomez-Blanco, J., Luque, D., Duquerroy, S., Caston, J.R., Goulas, T., Gomis-Ruth, X.F.
Deposit date:2015-04-28
Release date:2015-06-10
Modification date:2015-07-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and functional insights into Escherichia coli alpha 2-macroglobulin endopeptidase snap-trap inhibition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XAM
  • Download 4xam
  • View 4xam
Molmil generated image of 4xam
COMPLEMENT COMPONENT C4B
Descriptor:Complement C4b-A
Authors:Mortensen, S., Kidmose, R.T., Petersen, S.V., Szilagyi, A., Andersen, G.R.
Deposit date:2014-12-15
Release date:2015-05-06
Modification date:2015-05-27
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structural Basis for the Function of Complement Component C4 within the Classical and Lectin Pathways of Complement.
J Immunol., 194, 2015
4RTD
  • Download 4rtd
  • View 4rtd
Molmil generated image of 4rtd
ESCHERICHIA COLI ALPHA-2-MACROGLOBULIN ACTIVATED BY PORCINE ELASTASE
Descriptor:lipoprotein YfhM
Authors:Fyfe, C.D., Grinter, R., Roszak, A.W., Josts, I., Cogdell, R.J., Walker, D.
Deposit date:2014-11-14
Release date:2015-07-15
Modification date:2015-07-29
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structure of protease-cleaved Escherichia coli alpha-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment.
Acta Crystallogr.,Sect.D, 71, 2015
4U59
  • Download 4u59
  • View 4u59
Molmil generated image of 4u59
CRYSTAL STRUCTURE OF SALMONELLA ALPHA-2-MACROGLOBULIN REACTED WITH METHYLAMINE
Descriptor:alpha-2-macroglobulin
Authors:Wong, S.G., Dessen, A.
Deposit date:2014-07-24
Release date:2014-09-17
Modification date:2014-10-01
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structure of a bacterial alpha 2-macroglobulin reveals mimicry of eukaryotic innate immunity.
Nat Commun, 5, 2014
4U48
  • Download 4u48
  • View 4u48
Molmil generated image of 4u48
CRYSTAL STRUCTURE OF SALMONELLA ALPHA-2-MACROGLOBULIN
Descriptor:alpha-2-macroglobulin
Authors:Wong, S.G., Dessen, A.
Deposit date:2014-07-23
Release date:2014-09-17
Modification date:2015-09-23
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure of a bacterial alpha 2-macroglobulin reveals mimicry of eukaryotic innate immunity.
Nat Commun, 5, 2014
4U4J
  • Download 4u4j
  • View 4u4j
Molmil generated image of 4u4j
CRYSTAL STRUCTURE OF SALMONELLA ALPHA-2-MACROGLOBULIN MUTANT Y1175G
Descriptor:alpha-2-macroglobulin
Authors:Wong, S.G., Dessen, A.
Deposit date:2014-07-23
Release date:2014-09-17
Modification date:2014-10-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of a bacterial alpha 2-macroglobulin reveals mimicry of eukaryotic innate immunity.
Nat Commun, 5, 2014
4LNV
  • Download 4lnv
  • View 4lnv
Molmil generated image of 4lnv
CRYSTAL STRUCTURE OF TEP1S
Descriptor:Thioester-containing protein I
Authors:Le, B.V., Williams, M., Logarajah, S., Baxter, R.H.G.
Deposit date:2013-07-12
Release date:2013-07-24
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Molecular basis for genetic resistance of Anopheles gambiae to Plasmodium: structural analysis of TEP1 susceptible and resistant alleles.
Plos Pathog., 8, 2012
4FXG
  • Download 4fxg
  • View 4fxg
Molmil generated image of 4fxg
COMPLEMENT C4 IN COMPLEX WITH MASP-2
Descriptor:Complement C4-A, Mannan-binding lectin serine protease 2 (E.C.3.4.21.104)
Authors:Kidmose, R.T., Laursen, N.S., Andersen, G.R.
Deposit date:2012-07-03
Release date:2012-08-22
Modification date:2012-10-03
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Structural basis for activation of the complement system by component C4 cleavage.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FXK
  • Download 4fxk
  • View 4fxk
Molmil generated image of 4fxk
HUMAN COMPLEMENT C4
Descriptor:Complement C4-A
Authors:Kidmose, R.T., Laursen, N.S., Andersen, G.R.
Deposit date:2012-07-03
Release date:2012-08-22
Modification date:2012-10-03
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for activation of the complement system by component C4 cleavage.
Proc.Natl.Acad.Sci.USA, 109, 2012
4E0S
  • Download 4e0s
  • View 4e0s
Molmil generated image of 4e0s
CRYSTAL STRUCTURE OF C5B-6
Descriptor:Complement C5, Complement component C6
Authors:Aleshin, A.E., Stec, B., DiScipio, R., Liddington, R.C.
Deposit date:2012-03-05
Release date:2012-04-18
Modification date:2012-06-20
Method:X-RAY DIFFRACTION (4.21 Å)
Cite:Crystal structure of c5b-6 suggests structural basis for priming assembly of the membrane attack complex.
J.Biol.Chem., 287, 2012
4D94
  • Download 4d94
  • View 4d94
Molmil generated image of 4d94
CRYSTAL STRUCTURE OF TEP1R
Descriptor:Thioester-containing protein I
Authors:Le, B.V., Williams, M., Logarajah, S., Baxter, R.H.G.
Deposit date:2012-01-11
Release date:2012-10-17
Modification date:2012-10-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular Basis for Genetic Resistance of Anopheles gambiae to Plasmodium: Structural Analysis of TEP1 Susceptible and Resistant Alleles.
Plos Pathog., 8, 2012
<123>
PDBj@FacebookPDBj@TwitterwwPDBwwPDB FoundationEM DataBank

Copyright © 2013-2016 Protein Data Bank Japan
This is the static version of the PDBj web interface with limited functionality. Try the full version instead.