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2CAB	STRUCTURE, REFINEMENT AND FUNCTION OF CARBONIC ANHYDRASE ISOZYMES. REFINEMENT OF HUMAN CARBONIC ANHYDRASE I Descriptor: CARBONIC ANHYDRASE FORM B, ZINC ION Authors: Kannan, K.K, Ramanadham, M, Jones, T.A. Deposit date: 1983-10-05 Release date: 1984-02-02 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure, refinement, and function of carbonic anhydrase isozymes: refinement of human carbonic anhydrase I Ann.N.Y.Acad.Sci., 429, 1984
3CA2	CRYSTALLOGRAPHIC STUDIES OF INHIBITOR BINDING SITES IN HUMAN CARBONIC ANHYDRASE II. A PENTACOORDINATED BINDING OF THE SCN-ION TO THE ZINC AT HIGH P*H Descriptor: 3-MERCURI-4-AMINOBENZENESULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Eriksson, A.E, Jones, T.A, Liljas, A. Deposit date: 1989-10-02 Release date: 1990-01-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystallographic studies of inhibitor binding sites in human carbonic anhydrase II: a pentacoordinated binding of the SCN- ion to the zinc at high pH. Proteins, 4, 1988
1CA2	REFINED STRUCTURE OF HUMAN CARBONIC ANHYDRASE II AT 2.0 ANGSTROMS RESOLUTION Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Eriksson, A.E, Jones, T.A, Liljas, A. Deposit date: 1989-02-06 Release date: 1990-01-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Refined structure of human carbonic anhydrase II at 2.0 A resolution. Proteins, 4, 1988
2CA2	CRYSTALLOGRAPHIC STUDIES OF INHIBITOR BINDING SITES IN HUMAN CARBONIC ANHYDRASE II. A PENTACOORDINATED BINDING OF THE SCN-ION TO THE ZINC AT HIGH P*H Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, THIOCYANATE ION, ... Authors: Eriksson, A.E, Kylsten, P.M, Jones, T.A, Liljas, A. Deposit date: 1989-02-06 Release date: 1990-01-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystallographic studies of inhibitor binding sites in human carbonic anhydrase II: a pentacoordinated binding of the SCN- ion to the zinc at high pH. Proteins, 4, 1988
9CA2	ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE II Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Alexander, R.S, Christianson, D.W. Deposit date: 1991-07-09 Release date: 1992-07-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Engineering the hydrophobic pocket of carbonic anhydrase II. Biochemistry, 30, 1991
8CA2	ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE II Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Alexander, R.S, Christianson, D.W. Deposit date: 1991-07-09 Release date: 1992-07-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Engineering the hydrophobic pocket of carbonic anhydrase II. Biochemistry, 30, 1991
7CA2	ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE II Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Nair, S.K, Christianson, D.W. Deposit date: 1991-07-09 Release date: 1992-07-15 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Engineering the hydrophobic pocket of carbonic anhydrase II. Biochemistry, 30, 1991
6CA2	ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE II Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Alexander, R.S, Christianson, D.W. Deposit date: 1991-07-09 Release date: 1992-07-15 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Engineering the hydrophobic pocket of carbonic anhydrase II. Biochemistry, 30, 1991
12CA	ALTERING THE MOUTH OF A HYDROPHOBIC POCKET. STRUCTURE AND KINETICS OF HUMAN CARBONIC ANHYDRASE II MUTANTS AT RESIDUE VAL-121 Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Nair, S.K, Christianson, D.W. Deposit date: 1991-10-01 Release date: 1992-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Altering the mouth of a hydrophobic pocket. Structure and kinetics of human carbonic anhydrase II mutants at residue Val-121. J.Biol.Chem., 266, 1991
1CA3	UNEXPECTED PH-DEPENDENT CONFORMATION OF HIS-64, THE PROTON SHUTTLE OF CARBONIC ANHYDRASE II. Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Nair, S.K, Christianson, D.W. Deposit date: 1991-11-18 Release date: 1992-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Unexpected Ph-Dependent Conformation of His-64, the Proton Shuttle of Carbonic Anhydrase II. J.Am.Chem.Soc., 113, 1991
1HEB	STRUCTURAL CONSEQUENCES OF HYDROPHILIC AMINO-ACID SUBSTITUTIONS IN THE HYDROPHOBIC POCKET OF HUMAN CARBONIC ANHYDRASE II Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Nair, S.K, Christianson, D.W. Deposit date: 1992-07-16 Release date: 1992-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural consequences of hydrophilic amino acid substitutions in the hydrophobic pocket of human carbonic anhydrase II. Biochemistry, 32, 1993
1HEC	STRUCTURAL CONSEQUENCES OF HYDROPHILIC AMINO-ACID SUBSTITUTIONS IN THE HYDROPHOBIC POCKET OF HUMAN CARBONIC ANHYDRASE II Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Nair, S.K, Christianson, D.W. Deposit date: 1992-07-16 Release date: 1992-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural consequences of hydrophilic amino acid substitutions in the hydrophobic pocket of human carbonic anhydrase II. Biochemistry, 32, 1993
1HEA	CARBONIC ANHYDRASE II (CARBONATE DEHYDRATASE) (HCA II) (E.C.4.2.1.1) MUTANT WITH LEU 198 REPLACED BY ARG (L198R) Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Nair, S.K, Christianson, D.W. Deposit date: 1992-07-16 Release date: 1992-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural consequences of hydrophilic amino acid substitutions in the hydrophobic pocket of human carbonic anhydrase II. Biochemistry, 32, 1993
1HCA	UNEXPECTED PH-DEPENDENT CONFORMATION OF HIS-64, THE PROTON SHUTTLE OF CARBONIC ANHYDRASE II. Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Nair, S.K, Christianson, D.W. Deposit date: 1992-04-02 Release date: 1992-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Unexpected Ph-Dependent Conformation of His-64, the Proton Shuttle of Carbonic Anhydrase II. J.Am.Chem.Soc., 113, 1991
1HED	STRUCTURAL CONSEQUENCES OF HYDROPHILIC AMINO-ACID SUBSTITUTIONS IN THE HYDROPHOBIC POCKET OF HUMAN CARBONIC ANHYDRASE II Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Nair, S.K, Christianson, D.W. Deposit date: 1992-07-16 Release date: 1992-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural consequences of hydrophilic amino acid substitutions in the hydrophobic pocket of human carbonic anhydrase II. Biochemistry, 32, 1993
4CA2	ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE II Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Alexander, R.S, Christianson, D.W. Deposit date: 1991-06-08 Release date: 1992-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Engineering the hydrophobic pocket of carbonic anhydrase II. Biochemistry, 30, 1991
5CA2	CONFORMATIONAL MOBILITY OF HIS-64 IN THE THR-200 (RIGHT ARROW) SER MUTANT OF HUMAN CARBONIC ANHYDRASE II Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Alexander, R.S, Christianson, D.W. Deposit date: 1991-06-08 Release date: 1992-10-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Conformational mobility of His-64 in the Thr-200----Ser mutant of human carbonic anhydrase II. Biochemistry, 30, 1991
1DCA	STRUCTURE OF AN ENGINEERED METAL BINDING SITE IN HUMAN CARBONIC ANHYDRASE II REVEALS THE ARCHITECTURE OF A REGULATORY CYSTEINE SWITCH Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1992-12-18 Release date: 1993-07-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of an engineered His3Cys zinc binding site in human carbonic anhydrase II. Biochemistry, 32, 1993
1DCB	STRUCTURE OF AN ENGINEERED METAL BINDING SITE IN HUMAN CARBONIC ANHYDRASE II REVEALS THE ARCHITECTURE OF A REGULATORY CYSTEINE SWITCH Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1993-03-10 Release date: 1993-07-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of an engineered His3Cys zinc binding site in human carbonic anhydrase II. Biochemistry, 32, 1993
1CVB	STRUCTURAL AND FUNCTIONAL IMPORTANCE OF A CONSERVED HYDROGEN BOND NETWORK IN HUMAN CARBONIC ANHYDRASE II Descriptor: CARBONIC ANHYDRASE II, SULFATE ION, ZINC ION Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1993-02-04 Release date: 1993-10-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural and functional importance of a conserved hydrogen bond network in human carbonic anhydrase II. J.Biol.Chem., 268, 1993
1CVA	STRUCTURAL AND FUNCTIONAL IMPORTANCE OF A CONSERVED HYDROGEN BOND NETWORK IN HUMAN CARBONIC ANHYDRASE II Descriptor: AZIDE ION, CARBONIC ANHYDRASE II, ZINC ION Authors: Ippolito, J.A, Christianson, D.W. Deposit date: 1993-02-04 Release date: 1993-10-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural and functional importance of a conserved hydrogen bond network in human carbonic anhydrase II. J.Biol.Chem., 268, 1993
1BCD	X-RAY CRYSTALLOGRAPHIC STRUCTURE OF A COMPLEX BETWEEN HUMAN CARBONIC ANHYDRASE II AND A NEW TOPICAL INHIBITOR, TRIFLUOROMETHANE SULPHONAMIDE Descriptor: CARBONIC ANHYDRASE II, TRIFLUOROMETHANE SULFONAMIDE, ZINC ION Authors: Hakansson, K, Liljas, A. Deposit date: 1993-08-31 Release date: 1993-10-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The structure of a complex between carbonic anhydrase II and a new inhibitor, trifluoromethane sulphonamide. FEBS Lett., 350, 1994
1BIC	CRYSTALLOGRAPHIC ANALYSIS OF THR-200-> HIS HUMAN CARBONIC ANHYDRASE II AND ITS COMPLEX WITH THE SUBSTRATE, HCO3- Descriptor: BICARBONATE ION, CARBONIC ANHYDRASE II, METHYL MERCURY ION, ... Authors: Xue, Y, Vidgren, J, Svensson, L.A, Liljas, A, Jonsson, B.-H, Lindskog, S. Deposit date: 1992-09-01 Release date: 1993-10-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystallographic analysis of Thr-200-->His human carbonic anhydrase II and its complex with the substrate, HCO3-. Proteins, 15, 1993
2CBC	STRUCTURE OF NATIVE AND APO CARBONIC ANHYDRASE II AND SOME OF ITS ANION-LIGAND COMPLEXES Descriptor: CARBONIC ANHYDRASE II, FORMIC ACID, MERCURY (II) ION, ... Authors: Hakansson, K, Carlsson, M, Svensson, L.A, Liljas, A. Deposit date: 1992-06-01 Release date: 1993-10-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Structure of native and apo carbonic anhydrase II and structure of some of its anion-ligand complexes. J.Mol.Biol., 227, 1992
2CBB	STRUCTURE OF NATIVE AND APO CARBONIC ANHYDRASE II AND SOME OF ITS ANION-LIGAND COMPLEXES Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Hakansson, K, Carlsson, M, Svensson, L.A, Liljas, A. Deposit date: 1992-06-01 Release date: 1993-10-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Structure of native and apo carbonic anhydrase II and structure of some of its anion-ligand complexes. J.Mol.Biol., 227, 1992

 

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