PDB: 104 resultsInfo pagesStatus searchChemie searchBIRD

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4CO8	Structure of the DNA binding ETS domain of human ETV4 Descriptor: 1,2-ETHANEDIOL, ETS TRANSLOCATION VARIANT 4 Authors: Newman, J.A, Cooper, C.D.O, Shrestha, L, Burgess-Brown, N, Kopec, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2014-01-27 Release date: 2014-02-05 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.05 Å) Cite: Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation. J.Biol.Chem., 290, 2015
5ILU	Autoinhibited ETV4 Descriptor: ETS translocation variant 4 Authors: Whitby, F.G, Currie, S.L. Deposit date: 2016-03-04 Release date: 2017-02-22 Last modified: 2019-12-25 Method: X-RAY DIFFRACTION (1.101 Å) Cite: Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Res., 45, 2017
8EE9	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAATGGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-06 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.22 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EO4	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) with Di-methylated CpG sites Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-10-02 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.24 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8ENG	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) with Hemi-methylated CpG (forward strand) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*G*(5CM)P*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-29 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.25 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E3K	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-08-17 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.28 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EO1	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) with Hemi-methylated CpG (reverse strand) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-10-01 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.28 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E5Y	Human PU.1 ETS-Domain Bound to d(AATAAGCGGAAGTGGG) Acetate Free at pH 5.4 Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-08-22 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.32 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EBH	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAATGGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-08-31 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.33 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8SMH	Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2023-04-26 Release date: 2023-11-29 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors. Structure, 32, 2024
8EK3	Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAGCGGAATGGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-19 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.38 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EJ6	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAATGGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*AP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*TP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-16 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.39 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EQG	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAA(DU)GGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*DU*AP*AP*AP*TP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*AP*TP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-10-07 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.39 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E4H	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-08-18 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.39 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8SMJ	Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAATGGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2023-04-26 Release date: 2023-11-29 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.39 Å) Cite: Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors. Structure, 32, 2024
5ILS	Autoinhibited ETV1 Descriptor: ETS translocation variant 1 Authors: Whitby, F.G, Currie, S.L. Deposit date: 2016-03-04 Release date: 2017-02-22 Last modified: 2019-12-25 Method: X-RAY DIFFRACTION (1.399 Å) Cite: Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Res., 45, 2017
8EKZ	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGGAGAAGTAGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*GP*AP*GP*AP*AP*GP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*TP*AP*CP*TP*TP*CP*TP*CP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-22 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.42 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E3R	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-08-17 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.45 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EQK	Human PU.1 ETS-Domain (165-270) Bound to d(AATAACCGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-10-07 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.45 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EJ8	Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAAAGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), GLYCEROL, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-16 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.45 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8T9U	Human PU.1 ETS-domain (165-270) in complex with d(AATAAGCGIAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*IP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2023-06-26 Release date: 2023-11-29 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors. Structure, 32, 2024
8EKU	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAATGGAATGGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*AP*TP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*AP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-22 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.52 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EQL	Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAACCGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*TP*AP*T)-3'), SODIUM ION, ... Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-10-07 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.52 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
1GVJ	ETS-1 DNA BINDING AND AUTOINHIBITORY DOMAINS Descriptor: C-ETS-1 PROTEIN Authors: Tahirov, T.H, Ogata, K. Deposit date: 2002-02-14 Release date: 2004-02-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Crystal Structure of C-Ets-1 DNA-Binding and Autoinhibitory Domains To be Published
8EKJ	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAATGGAAGTGGG) Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*AP*TP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*AP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 Authors: Terrell, J.R, Poon, G.M.K. Deposit date: 2022-09-21 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.54 Å) Cite: DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023

 

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