2DHI
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SOLUTION STRUCTURE OF THE PH DOMAIN OF EVECTIN-2 FROM MOUSE
Descriptor:Pleckstrin homology domain-containing family B member 2
Authors:Li, H., Yoneyama, M., Koshiba, S., Inoue, M., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-24
Release date:2006-09-24
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the PH domain of Evectin-2 from mouse
To be Published
1AWE
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HUMAN SOS1 PLECKSTRIN HOMOLOGY (PH) DOMAIN, NMR, 20 STRUCTURES
Descriptor:SOS1
Authors:Zheng, J., Cowburn, D.
Deposit date:1997-10-01
Release date:1998-02-25
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains.
J.Biol.Chem., 272, 1997
1BAK
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SIGNAL TRANSDUCTION PLECKSTRIN HOMOLOGY DOMAIN OF G-PROTEIN COUPLED RECEPTOR KINASE 2 (BETA-ADRENERGIC RECEPTOR KINASE 1), C-TERMINAL EXTENDED, NMR, 20 STRUCTURES
Descriptor:G-PROTEIN COUPLED RECEPTOR KINASE 2
Authors:Fushman, D., Cowburn, D.
Deposit date:1997-11-21
Release date:1998-02-25
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The solution structure and dynamics of the pleckstrin homology domain of G protein-coupled receptor kinase 2 (beta-adrenergic receptor kinase 1). A binding partner of Gbetagamma subunits.
J.Biol.Chem., 273, 1998
1DRO
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NMR STRUCTURE OF THE CYTOSKELETON/SIGNAL TRANSDUCTION PROTEIN
Descriptor:BETA-SPECTRIN
Authors:Zhang, P., Talluri, S., Deng, H., Branton, D., Wagner, G.
Deposit date:1995-09-29
Release date:1996-04-03
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the pleckstrin homology domain of Drosophila beta-spectrin.
Structure, 3, 1995
1DYN
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CRYSTAL STRUCTURE AT 2.2 ANGSTROMS RESOLUTION OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM HUMAN DYNAMIN
Descriptor:DYNAMIN (PLECKSTRIN HOMOLOGY DOMAIN) (DYNPH)
Authors:Ferguson, K.M., Lemmon, M.A., Schlessinger, J., Sigler, P.B.
Deposit date:1994-12-21
Release date:1995-02-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure at 2.2 A resolution of the pleckstrin homology domain from human dynamin.
Cell(Cambridge,Mass.), 79, 1994
1EAZ
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CRYSTAL STRUCTURE OF THE PHOSPHOINOSITOL (3,4)-BISPHOSPHATE BINDING PH DOMAIN OF TAPP1 FROM HUMAN.
Descriptor:TANDEM PH DOMAIN CONTAINING PROTEIN-1
Authors:Thomas, C.C., Dowler, S., Deak, M., Alessi, D.R., Van Aalten, D.M.F.
Deposit date:2001-07-17
Release date:2002-07-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of the Phosphatidylinositol 3,4-Bisphosphate-Binding Pleckstrin Homology (Ph) Domain of Tandem Ph-Domain-Containing Protein 1 (Tapp1): Molecular Basis of Lipid Specificity
Biochem.J., 358, 2001
1FAO
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STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM DAPP1/PHISH IN COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE
Descriptor:DUAL ADAPTOR OF PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDES
Authors:Ferguson, K.M., Kavran, J.M., Sankaran, V.G., Fournier, E., Isakoff, S.J., Skolnik, E.Y., Lemmon, M.A.
Deposit date:2000-07-13
Release date:2000-07-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains.
Mol.Cell, 6, 2000
1FB8
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STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM DAPP1/PHISH
Descriptor:DUAL ADAPTOR OF PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDES
Authors:Ferguson, K.M., Kavran, J.M., Sankaran, V.G., Fournier, E., Isakoff, S.J., Skolnik, E.Y., Lemmon, M.A.
Deposit date:2000-07-14
Release date:2000-07-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains.
Mol.Cell, 6, 2000
1FGY
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GRP1 PH DOMAIN WITH INS(1,3,4,5)P4
Descriptor:GRP1
Authors:Lietzke, S.E., Bose, S., Cronin, T., Klarlund, J., Chawla, A., Czech, M.P., Lambright, D.G.
Deposit date:2000-07-29
Release date:2000-08-23
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains.
Mol.Cell, 6, 2000
1FGZ
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GRP1 PH DOMAIN (UNLIGANDED)
Descriptor:GRP1 PH DOMAIN (UNLIGANDED)
Authors:Lietzke, S.E., Bose, S., Cronin, T., Klarlund, J., Chawla, A., Czech, M.P., Lambright, D.G.
Deposit date:2000-07-29
Release date:2000-08-23
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains.
Mol.Cell, 6, 2000
1FHW
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STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM GRP1 IN COMPLEX WITH INOSITOL(1,3,4,5,6)PENTAKISPHOSPHATE
Descriptor:GUANINE NUCLEOTIDE EXCHANGE FACTOR AND INTEGRIN BINDING PROTEIN HOMOLOG GRP1
Authors:Ferguson, K.M., Kavran, J.M., Sankaran, V.G., Fournier, E., Isakoff, S.J., Skolnik, E.Y., Lemmon, M.A.
Deposit date:2000-08-02
Release date:2000-08-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
Mol.Cell, 6, 2000
1FHX
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STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM GRP1 IN COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE
Descriptor:GUANINE NUCLEOTIDE EXCHANGE FACTOR AND INTEGRIN BINDING PROTEIN HOMOLOG GRP1
Authors:Ferguson, K.M., Kavran, J.M., Sankaran, V.G., Fournier, E., Isakoff, S.J., Skolnik, E.Y., Lemmon, M.A.
Deposit date:2000-08-02
Release date:2000-08-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
Mol.Cell, 6, 2000
1H10
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HIGH RESOLUTION STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN OF PROTEIN KINASE B/AKT BOUND TO INS(1,3,4,5)-TETRAKISPHOPHATE
Descriptor:RAC-ALPHA SERINE/THREONINE KINASE (E.C.2.7.1.-)
Authors:Thomas, C.C., Deak, M., Alessi, D.R., Van Aalten, D.M.F.
Deposit date:2002-07-01
Release date:2003-06-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:High Resolution Structure of the Pleckstrin Homology Domain of Protein Kinase B/Akt Bound to Phosphatidylinositol (3,4,5)-Trisphosphate
Curr.Biol., 12, 2002
1P6S
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SOLUTION STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN OF HUMAN PROTEIN KINASE B BETA (PKB/AKT)
Descriptor:RAC-beta serine/threonine protein kinase (E.C.2.7.1.-)
Authors:Auguin, D., Barthe, P., Auge-Senegas, M.T., Stern, M.H., Noguchi, M., Roumestand, C.
Deposit date:2003-04-30
Release date:2004-05-18
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure and backbone dynamics of the pleckstrin homology domain of the human protein kinase B (PKB/Akt). Interaction with inositol phosphates.
J.BIOMOL.NMR, 28, 2004
1PLS
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SOLUTION STRUCTURE OF A PLECKSTRIN HOMOLOGY DOMAIN
Descriptor:PLECKSTRIN (N-TERMINAL PLECKSTRIN HOMOLOGY DOMAIN) MUTANT WITH LEU GLU (HIS)6 ADDED TO THE C TERMINUS (INS(G105-LEHHHHHH)) (NMR, 25 STRUCTURES)
Authors:Yoon, H.S., Hajduk, P.J., Petros, A.M., Olejniczak, E.T., Meadows, R.P., Fesik, S.W.
Deposit date:1994-05-03
Release date:1995-06-03
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of a pleckstrin-homology domain.
Nature, 369, 1994
1U27
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TRIGLYCINE VARIANT OF THE ARNO PLECKSTRIN HOMOLOGY DOMAIN IN COMPLEX WITH INS(1,3,4,5)P4
Descriptor:Cytohesin 2
Authors:Cronin, T.C., DiNitto, J.P., Czech, M.P., Lambright, D.G.
Deposit date:2004-07-16
Release date:2005-02-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains
Embo J., 23, 2004
1U2B
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TRIGLYCINE VARIANT OF THE GRP1 PLECKSTRIN HOMOLOGY DOMAIN UNLIGANDED
Descriptor:Cytohesin 3
Authors:Cronin, T.C., DiNitto, J.P., Czech, M.P., Lambright, D.G.
Deposit date:2004-07-16
Release date:2005-02-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains
Embo J., 23, 2004
1U5D
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CRYSTAL STRUCTURE OF THE PH DOMAIN OF SKAP55
Descriptor:Src Kinase-associated Phosphoprotein of 55 kDa
Authors:Tang, Y., Swanson, K.D., Neel, B.G., Eck, M.J.
Deposit date:2004-07-27
Release date:2005-07-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for the Dimerization and Phosphoinositide Specificity of the Src Kinase-associated Phosphoproteins SKAP55 and SKAP-Hom
To be Published
1U5E
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CRYSTAL STRUCTURE OF A N-TERMINAL FRAGMENT OF SKAP-HOM CONTAINING BOTH THE HELICAL DIMERIZATION DOMAIN AND THE PH DOMAIN
Descriptor:Src-associated adaptor protein
Authors:Tang, Y., Swanson, K.D., Neel, B.G., Eck, M.J.
Deposit date:2004-07-27
Release date:2005-07-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for the Dimerization and Phosphoinositide Specificity of the Src Kinase-associated Phosphoproteins SKAP55 and SKAP-Hom
To be Published
1U5F
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CRYSTAL STRUCTURE OF THE PH DOMAIN OF SKAP-HOM WITH 8 VECTOR-DERIVED N-TERMINAL RESIDUES
Descriptor:Src-associated adaptor protein
Authors:Tang, Y., Swanson, K.D., Neel, B.G., Eck, M.J.
Deposit date:2004-07-27
Release date:2005-07-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for the Dimerization and Phosphoinositide Specificity of the Src Kinase-associated Phosphoproteins SKAP55 and SKAP-Hom
To be Published
1U5G
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CRYSTAL STRUCTURE OF THE PH DOMAIN OF SKAP-HOM
Descriptor:Src-associated adaptor protein
Authors:Tang, Y., Swanson, K., Neel, B.G., Eck, M.J.
Deposit date:2004-07-27
Release date:2005-07-26
Modification date:2009-11-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Skap-hom dimerization and PH domains comprise a 3'-phosphoinositide-gated molecular switch.
Mol.Cell, 32, 2008
1UNP
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CRYSTAL STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN OF PKB ALPHA
Descriptor:RAC-ALPHA SERINE/THREONINE KINASE (E.C.2.7.1.-)
Authors:Milburn, C.C., Deak, M., Kelly, S.M., Price, N.C., Alessi, D.R., Van Aalten, D.M.F.
Deposit date:2003-09-12
Release date:2004-09-16
Modification date:2009-09-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Binding of Phosphatidylinositol 3,4,5-Trisphosphate to the Pleckstrin Homology Domain of Protein Kinase B Induces a Conformational Change
Biochem.J., 375, 2003
1UNQ
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HIGH RESOLUTION CRYSTAL STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN OF PROTEIN KINASE B/AKT BOUND TO INS (1,3,4,5)-TETRAKISPHOPHATE
Descriptor:RAC-ALPHA SERINE/THREONINE KINASE (E.C.2.7.1.-)
Authors:Milburn, C.C., Deak, M., Kelly, S.M., Price, N.C., Alessi, D.R., Van Aalten, D.M.F.
Deposit date:2003-09-12
Release date:2004-09-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Binding of Phosphatidylinositol 3,4,5-Trisphosphate to the Pleckstrin Homology Domain of Protein Kinase B Induces a Conformational Change
Biochem.J., 375, 2003
1UNR
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CRYSTAL STRUCTURE OF THE PH DOMAIN OF PKB ALPHA IN COMPLEX WITH A SULFATE MOLECULE
Descriptor:RAC-ALPHA SERINE/THREONINE KINASE (E.C.2.7.11.1)
Authors:Milburn, C.C., Deak, M., Kelly, S.M., Price, N.C., Alessi, D.R., Van Aalten, D.M.F.
Deposit date:2003-09-15
Release date:2004-09-16
Modification date:2009-09-01
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Binding of Phosphatidylinositol 3,4,5-Trisphosphate to the Pleckstrin Homology Domain of Protein Kinase B Induces a Conformational Change
Biochem.J., 375, 2003
1UPQ
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CRYSTAL STRUCTURE OF THE PLECKSTRIN HOMOLOGY (PH) DOMAIN OF PEPP1
Descriptor:PEPP1
Authors:Milburn, C.C., Komander, D., Deak, M., Alessi, D.R., Van Aalten, D.M.F.
Deposit date:2003-10-09
Release date:2004-10-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal Structure of the Pleckstrin Homology Domain of Pepp1
To be Published
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