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1AFC
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1afc
STRUCTURAL STUDIES OF THE BINDING OF THE ANTI-ULCER DRUG SUCROSE OCTASULFATE TO ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:ACIDIC FIBROBLAST GROWTH FACTOR (AFGF) MUTANT WITH CYS 47 REPLACED BY ALA (C47A) COMPLEX WITH SUCROSE OCTASULFATE
Authors:Zhu, X., Hsu, B.T., Rees, D.C.
Deposit date:1993-07-13
Release date:1993-10-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of the binding of the anti-ulcer drug sucrose octasulfate to acidic fibroblast growth factor.
Structure, 1, 1993
1AXM
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1axm
HEPARIN-LINKED BIOLOGICALLY-ACTIVE DIMER OF FIBROBLAST GROWTH FACTOR
Descriptor:ACIDIC FIBROBLAST GROWTH FACTOR
Authors:DiGabriele, A.D., Lax, I., Chen, D.I., Svahn, C.M., Jaye, M., Schlessinger, J., Hendrickson, W.A.
Deposit date:1997-10-16
Release date:1998-04-22
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a heparin-linked biologically active dimer of fibroblast growth factor.
Nature, 393, 1998
1BAR
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1bar
THREE-DIMENSIONAL STRUCTURES OF ACIDIC AND BASIC FIBROBLAST GROWTH FACTORS
Descriptor:ACIDIC FIBROBLAST GROWTH FACTOR (AFGF) MUTANT WITH CYS 47 REPLACED BY ALA AND HIS 93 REPLACED BY GLY (C47A,H93G)
Authors:Zhu, X., Komiya, H., Chirino, A., Faham, S., Fox, G.M., Arakawa, T., Hsu, B.T., Rees, D.C.
Deposit date:1992-09-29
Release date:1993-10-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Three-dimensional structures of acidic and basic fibroblast growth factors.
Science, 251, 1991
1BAS
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1bas
THREE-DIMENSIONAL STRUCTURES OF ACIDIC AND BASIC FIBROBLAST GROWTH FACTORS
Descriptor:BASIC FIBROBLAST GROWTH FACTOR (BFGF) MUTANT WITH CYS 70 REPLACED BY SER AND CYS 88 REPLACED BY SER (C70S,C88S)
Authors:Chirino, A.J., Rees, D.C.
Deposit date:1992-09-29
Release date:1993-10-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Three-dimensional structures of acidic and basic fibroblast growth factors.
Science, 251, 1991
1BFB
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1bfb
BASIC FIBROBLAST GROWTH FACTOR COMPLEXED WITH HEPARIN TETRAMER FRAGMENT
Descriptor:BASIC FIBROBLAST GROWTH FACTOR
Authors:Faham, S., Rees, D.C.
Deposit date:1995-12-12
Release date:1996-04-03
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Heparin structure and interactions with basic fibroblast growth factor.
Science, 271, 1996
1BFC
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1bfc
BASIC FIBROBLAST GROWTH FACTOR COMPLEXED WITH HEPARIN HEXAMER FRAGMENT
Descriptor:BASIC FIBROBLAST GROWTH FACTOR
Authors:Faham, S., Rees, D.C.
Deposit date:1995-12-12
Release date:1996-04-03
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Heparin structure and interactions with basic fibroblast growth factor.
Science, 271, 1996
1BFF
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1bff
THE 154 AMINO ACID FORM OF HUMAN BASIC FIBROBLAST GROWTH FACTOR
Descriptor:BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL
Authors:Kastrup, J.S., Eriksson, E.S.
Deposit date:1996-12-06
Release date:1997-06-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of the 154-amino-acid form of recombinant human basic fibroblast growth factor. comparison with the truncated 146-amino-acid form.
Acta Crystallogr.,Sect.D, 53, 1997
1BFG
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1bfg
CRYSTAL STRUCTURE OF BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION
Descriptor:BASIC FIBROBLAST GROWTH FACTOR MUTANT WITH CYS 69 REPLACED BY SER AND CYS 87 REPLACED BY SER (C69S,C87S)
Authors:Kitagawa, Y., Ago, H., Katsube, Y., Fujishima, A., Matsuura, Y.
Deposit date:1993-04-15
Release date:1994-01-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of basic fibroblast growth factor at 1.6 A resolution.
J.Biochem.(Tokyo), 110, 1991
1BLA
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1bla
BASIC FIBROBLAST GROWTH FACTOR (FGF-2) MUTANT WITH CYS 78 REPLACED BY SER AND CYS 96 REPLACED BY SER, NMR
Descriptor:BASIC FIBROBLAST GROWTH FACTOR
Authors:Powers, R., Seddon, A.P., Bohlen, P., Moy, F.J.
Deposit date:1996-05-20
Release date:1996-11-08
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:High-resolution solution structure of basic fibroblast growth factor determined by multidimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry, 35, 1996
1BLD
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1bld
BASIC FIBROBLAST GROWTH FACTOR (FGF-2) MUTANT WITH CYS 78 REPLACED BY SER AND CYS 96 REPLACED BY SER, NMR
Descriptor:BASIC FIBROBLAST GROWTH FACTOR
Authors:Powers, R., Seddon, A.P., Bohlen, P., Moy, F.J.
Deposit date:1996-05-20
Release date:1996-11-08
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:High-resolution solution structure of basic fibroblast growth factor determined by multidimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry, 35, 1996
1DJS
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1djs
LIGAND-BINDING PORTION OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 IN COMPLEX WITH FGF1
Descriptor:FIBROBLAST GROWTH FACTOR RECEPTOR 2 IN COMPLEX WITH FGF1
Authors:Stauber, D.J., Digabriele, A.D., Hendrickson, W.A.
Deposit date:1999-12-03
Release date:2000-01-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural interactions of fibroblast growth factor receptor with its ligands.
Proc.Natl.Acad.Sci.USA, 97, 2000
1DZC
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1dzc
HIGH RESOLUTION STRUCTURE OF ACIDIC FIBROBLAST GROWTH FACTOR. MUTANT FGF-4-ALA-(24-154), 24 NMR STRUCTURES
Descriptor:FIBROBLAST GROWTH FACTOR 1
Authors:Lozano, R.M., Pineda-Lucena, A., Gonzalez, C., Jimenez, M.A., Cuevas, P., Redondo-Horcajo, M., Sanz, J.M., Rico, M., Gimenez-Gallego, G.
Deposit date:2000-02-24
Release date:2000-03-16
Modification date:2013-05-15
Method:SOLUTION NMR
Cite:1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor
Biochemistry, 39, 2000
1DZD
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1dzd
HIGH RESOLUTION STRUCTURE OF ACIDIC FIBROBLAST GROWTH FACTOR (27-154), 24 NMR STRUCTURES
Descriptor:ACIDIC FIBROBLAST GROWTH FACTOR
Authors:Lozano, R.M., Pineda-Lucena, A., Gonzalez, C., Jimenez, M.A., Cuevas, P., Redondo-Horcajo, M., Sanz, J.M., Rico, M., Gimenez-Gallego, G.
Deposit date:2000-02-24
Release date:2000-03-16
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor
Biochemistry, 39, 2000
1FGA
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1fga
REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION
Descriptor:BASIC FIBROBLAST GROWTH FACTOR (HB/FGF) DETERMINED WITH AMMOMIUM SELENATE
Authors:Eriksson, A.E., Matthews, B.W.
Deposit date:1993-02-26
Release date:1993-07-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution.
Protein Sci., 2, 1993
1FMM
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1fmm
SOLUTION STRUCTURE OF NFGF-1
Descriptor:ACIDIC FIBROBLAST GROWTH FACTOR
Authors:Arunkumar, A.I., Srisailam, S., Kumar, T.K.S., Chiu, I.M., Yu, C.
Deposit date:2000-08-18
Release date:2001-08-18
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structure and stability of an acidic fibroblast growth factor from Notophthalmus viridescens.
J.Biol.Chem., 277, 2002
1G82
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1g82
STRUCTURE OF FIBROBLAST GROWTH FACTOR 9
Descriptor:FIBROBLAST GROWTH FACTOR 9
Authors:Hecht, H.J., Adar, R., Hofmann, B., Bogin, O., Weich, H., Yayon, A.
Deposit date:2000-11-16
Release date:2001-03-07
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of fibroblast growth factor 9 shows a symmetric dimer with unique receptor- and heparin-binding interfaces.
Acta Crystallogr.,Sect.D, 57, 2001
1HKN
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1hkn
A COMPLEX BETWEEN ACIDIC FIBROBLAST GROWTH FACTOR AND 5-AMINO-2-NAPHTHALENESULFONATE
Descriptor:HEPARIN-BINDING GROWTH FACTOR 1
Authors:Fernandez-Tornero, C., Lozano, R.M., Gimenez-Gallego, G., Romero, A.
Deposit date:2003-03-10
Release date:2004-03-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity: Crystal Structure of Acidic Fibroblast Growth Factor in Complex with 5-Amino-2-Naphthalenesulfonate
J.Biol.Chem., 278, 2003
1IHK
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1ihk
CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 9 (FGF9)
Descriptor:GLIA-ACTIVATING FACTOR
Authors:Plotnikov, A.N., Eliseenkova, A.V., Ibrahimi, O.A., Lemmon, M.A., Mohammadi, M.
Deposit date:2001-04-19
Release date:2001-05-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibition.
J.Biol.Chem., 276, 2001
1IJT
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1ijt
CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 4 (FGF4)
Descriptor:fibroblast growth factor 4
Authors:Bellosta, P., Plotnikov, A.N., Eliseenkova, A.V., Basilico, C., Mohammadi, M.
Deposit date:2001-04-29
Release date:2001-08-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification of receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis.
Mol.Cell.Biol., 21, 2001
1JQZ
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1jqz
HUMAN ACIDIC FIBROBLAST GROWTH FACTOR. 141 AMINO ACID FORM WITH AMINO TERMINAL HIS TAG.
Descriptor:acidic fibroblast growth factor
Authors:Brych, S.R., Blaber, S.I., Logan, T.M., Blaber, M.
Deposit date:2001-08-09
Release date:2001-12-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1JT3
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1jt3
HUMAN ACIDIC FIBROBLAST GROWTH FACTOR. 141 AMINO ACID FORM WITH AMINO HISTIDINE TAG AND LEU 73 REPLACED BY VAL (L73V)
Descriptor:acidic fibroblast growth factor
Authors:Brych, S.R., Blaber, S.I., Logan, T.M., Blaber, M.
Deposit date:2001-08-20
Release date:2001-12-19
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1JT4
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1jt4
HUMAN ACIDIC FIBROBLAST GROWTH FACTOR. 141 AMINO ACID FORM WITH AMINO TERMINAL HIS TAG AND VAL 109 REPLACED BY LEU (V109L)
Descriptor:acidic fibroblast growth factor
Authors:Brych, S.R., Blaber, S.I., Logan, T.M., Blaber, M.
Deposit date:2001-08-20
Release date:2001-12-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1JT5
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1jt5
HUMAN ACIDIC FIBROBLAST GROWTH FACTOR. 141 AMINO ACID FORM WITH AMINO TERMINAL HIS TAG AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L73V/V109L)
Descriptor:acidic fibroblast growth factor
Authors:Brych, S.R., Blaber, S.I., Logan, T.M., Blaber, M.
Deposit date:2001-08-20
Release date:2001-12-19
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1JT7
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1jt7
HUMAN ACIDIC FIBROBLAST GROWTH FACTOR. 141 AMINO ACID FORM WITH AMINO TERMINAL HIS TAG AND LEU 44 REPLACED BY PHE AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L44F/L73V/V109L)
Descriptor:acidic fibroblast growth factor
Authors:Brych, S.R., Blaber, S.I., Logan, T.M., Blaber, M.
Deposit date:2001-08-20
Release date:2001-12-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1JTC
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1jtc
HUMAN ACIDIC FIBROBLAST GROWTH FACTOR. 141 AMINO ACID FORM WITH AMINO TERMINAL HIS TAG AND LEU 44 REPLACED BY PHE (L44F)
Descriptor:acidic fibroblast growth factor
Authors:Brych, S.R., Blaber, S.I., Logan, T.M., Blaber, M.
Deposit date:2001-08-20
Release date:2001-12-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
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