2FGF
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THREE-DIMENSIONAL STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR, A STRUCTURAL HOMOLOG OF INTERLEUKIN 1BETA
Descriptor:BASIC FIBROBLAST GROWTH FACTOR
Authors:Zhang, J., Sprang, S.R.
Deposit date:1991-02-19
Release date:1992-01-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Three-dimensional structure of human basic fibroblast growth factor, a structural homolog of interleukin 1 beta.
Proc.Natl.Acad.Sci.USA, 88, 1991
1BAR
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THREE-DIMENSIONAL STRUCTURES OF ACIDIC AND BASIC FIBROBLAST GROWTH FACTORS
Descriptor:ACIDIC FIBROBLAST GROWTH FACTOR (AFGF) MUTANT WITH CYS 47 REPLACED BY ALA AND HIS 93 REPLACED BY GLY (C47A,H93G)
Authors:Zhu, X., Komiya, H., Chirino, A., Faham, S., Fox, G.M., Arakawa, T., Hsu, B.T., Rees, D.C.
Deposit date:1992-09-29
Release date:1993-10-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Three-dimensional structures of acidic and basic fibroblast growth factors.
Science, 251, 1991
1BAS
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THREE-DIMENSIONAL STRUCTURES OF ACIDIC AND BASIC FIBROBLAST GROWTH FACTORS
Descriptor:BASIC FIBROBLAST GROWTH FACTOR (BFGF) MUTANT WITH CYS 70 REPLACED BY SER AND CYS 88 REPLACED BY SER (C70S,C88S)
Authors:Chirino, A.J., Rees, D.C.
Deposit date:1992-09-29
Release date:1993-10-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Three-dimensional structures of acidic and basic fibroblast growth factors.
Science, 251, 1991
1FGA
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REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION
Descriptor:BASIC FIBROBLAST GROWTH FACTOR (HB/FGF) DETERMINED WITH AMMOMIUM SELENATE
Authors:Eriksson, A.E., Matthews, B.W.
Deposit date:1993-02-26
Release date:1993-07-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution.
Protein Sci., 2, 1993
4FGF
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REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION
Descriptor:BASIC FIBROBLAST GROWTH FACTOR (HB/FGF)
Authors:Eriksson, A.E., Matthews, B.W.
Deposit date:1993-02-26
Release date:1993-07-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution.
Protein Sci., 2, 1993
1BFG
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CRYSTAL STRUCTURE OF BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION
Descriptor:BASIC FIBROBLAST GROWTH FACTOR MUTANT WITH CYS 69 REPLACED BY SER AND CYS 87 REPLACED BY SER (C69S,C87S)
Authors:Kitagawa, Y., Ago, H., Katsube, Y., Fujishima, A., Matsuura, Y.
Deposit date:1993-04-15
Release date:1994-01-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of basic fibroblast growth factor at 1.6 A resolution.
J.Biochem.(Tokyo), 110, 1991
1AFC
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STRUCTURAL STUDIES OF THE BINDING OF THE ANTI-ULCER DRUG SUCROSE OCTASULFATE TO ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:ACIDIC FIBROBLAST GROWTH FACTOR (AFGF) MUTANT WITH CYS 47 REPLACED BY ALA (C47A) COMPLEX WITH SUCROSE OCTASULFATE
Authors:Zhu, X., Hsu, B.T., Rees, D.C.
Deposit date:1993-07-13
Release date:1993-10-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of the binding of the anti-ulcer drug sucrose octasulfate to acidic fibroblast growth factor.
Structure, 1, 1993
2BFH
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CRYSTAL STRUCTURE OF BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION
Descriptor:BASIC FIBROBLAST GROWTH FACTOR (WILD TYPE)
Authors:Kitagawa, Y., Ago, H., Katsube, Y., Fujishima, A., Matsuura, Y.
Deposit date:1993-08-31
Release date:1994-01-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of basic fibroblast growth factor at 1.6 A resolution.
J.Biochem.(Tokyo), 110, 1991
2AFG
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2.0 ANGSTROM X-RAY STRUCTURE OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:ACIDIC FIBROBLAST GROWTH FACTOR
Authors:Blaber, M., Disalvo, J., Thomas, K.A.
Deposit date:1995-07-21
Release date:1995-10-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray crystal structure of human acidic fibroblast growth factor.
Biochemistry, 35, 1996
1BFB
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BASIC FIBROBLAST GROWTH FACTOR COMPLEXED WITH HEPARIN TETRAMER FRAGMENT
Descriptor:BASIC FIBROBLAST GROWTH FACTOR
Authors:Faham, S., Rees, D.C.
Deposit date:1995-12-12
Release date:1996-04-03
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Heparin structure and interactions with basic fibroblast growth factor.
Science, 271, 1996
1BFC
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BASIC FIBROBLAST GROWTH FACTOR COMPLEXED WITH HEPARIN HEXAMER FRAGMENT
Descriptor:BASIC FIBROBLAST GROWTH FACTOR
Authors:Faham, S., Rees, D.C.
Deposit date:1995-12-12
Release date:1996-04-03
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Heparin structure and interactions with basic fibroblast growth factor.
Science, 271, 1996
1BLA
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BASIC FIBROBLAST GROWTH FACTOR (FGF-2) MUTANT WITH CYS 78 REPLACED BY SER AND CYS 96 REPLACED BY SER, NMR
Descriptor:BASIC FIBROBLAST GROWTH FACTOR
Authors:Powers, R., Seddon, A.P., Bohlen, P., Moy, F.J.
Deposit date:1996-05-20
Release date:1996-11-08
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:High-resolution solution structure of basic fibroblast growth factor determined by multidimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry, 35, 1996
1BLD
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BASIC FIBROBLAST GROWTH FACTOR (FGF-2) MUTANT WITH CYS 78 REPLACED BY SER AND CYS 96 REPLACED BY SER, NMR
Descriptor:BASIC FIBROBLAST GROWTH FACTOR
Authors:Powers, R., Seddon, A.P., Bohlen, P., Moy, F.J.
Deposit date:1996-05-20
Release date:1996-11-08
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:High-resolution solution structure of basic fibroblast growth factor determined by multidimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry, 35, 1996
1BFF
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THE 154 AMINO ACID FORM OF HUMAN BASIC FIBROBLAST GROWTH FACTOR
Descriptor:BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL
Authors:Kastrup, J.S., Eriksson, E.S.
Deposit date:1996-12-06
Release date:1997-06-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of the 154-amino-acid form of recombinant human basic fibroblast growth factor. comparison with the truncated 146-amino-acid form.
Acta Crystallogr.,Sect.D, 53, 1997
1AXM
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HEPARIN-LINKED BIOLOGICALLY-ACTIVE DIMER OF FIBROBLAST GROWTH FACTOR
Descriptor:ACIDIC FIBROBLAST GROWTH FACTOR
Authors:DiGabriele, A.D., Lax, I., Chen, D.I., Svahn, C.M., Jaye, M., Schlessinger, J., Hendrickson, W.A.
Deposit date:1997-10-16
Release date:1998-04-22
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a heparin-linked biologically active dimer of fibroblast growth factor.
Nature, 393, 1998
2AXM
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HEPARIN-LINKED BIOLOGICALLY-ACTIVE DIMER OF FIBROBLAST GROWTH FACTOR
Descriptor:ACIDIC FIBROBLAST GROWTH FACTOR
Authors:Digabriele, A.D., Lax, I., Chen, D.I., Svahn, C.M., Jaye, M., Schlessinger, J., Hendrickson, W.A.
Deposit date:1997-10-20
Release date:1998-04-22
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a heparin-linked biologically active dimer of fibroblast growth factor.
Nature, 393, 1998
1RML
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NMR STUDY OF ACID FIBROBLAST GROWTH FACTOR BOUND TO 1,3,6-NAPHTHALENE TRISULPHONATE, 26 STRUCTURES
Descriptor:ACIDIC FIBROBLAST GROWTH FACTOR, NAPHTHALENE TRISULFONATE
Authors:Lozano, R.M., Jimenez, M.A., Santoro, J., Rico, M., Gimenez-Gallego, G.
Deposit date:1998-05-21
Release date:1998-11-11
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of acidic fibroblast growth factor bound to 1,3, 6-naphthalenetrisulfonate: a minimal model for the anti-tumoral action of suramins and suradistas.
J.Mol.Biol., 281, 1998
1QQK
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THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7 (KERATINOCYTE GROWTH FACTOR)
Descriptor:FIBROBLAST GROWTH FACTOR 7
Authors:Ye, S., Luo, Y., Pelletier, H., McKeehan, W.L.
Deposit date:1999-06-07
Release date:2000-01-14
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.
Biochemistry, 40, 2001
1QQL
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THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7/1 CHIMERA
Descriptor:FIBROBLAST GROWTH FACTOR 7/1 CHIMERA
Authors:Ye, S., Luo, Y., Pelletier, H., McKeehan, W.L.
Deposit date:1999-06-07
Release date:2000-01-14
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.
Biochemistry, 40, 2001
1CVS
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CRYSTAL STRUCTURE OF A DIMERIC FGF2-FGFR1 COMPLEX
Descriptor:FIBROBLAST GROWTH FACTOR 1
Authors:Plotnikov, A.N., Schlessinger, J., Hubbard, S.R., Mohammadi, M.
Deposit date:1999-08-24
Release date:2000-01-28
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for FGF receptor dimerization and activation.
Cell(Cambridge,Mass.), 98, 1999
1DJS
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LIGAND-BINDING PORTION OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 IN COMPLEX WITH FGF1
Descriptor:FIBROBLAST GROWTH FACTOR RECEPTOR 2 IN COMPLEX WITH FGF1
Authors:Stauber, D.J., Digabriele, A.D., Hendrickson, W.A.
Deposit date:1999-12-03
Release date:2000-01-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural interactions of fibroblast growth factor receptor with its ligands.
Proc.Natl.Acad.Sci.USA, 97, 2000
1DZC
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HIGH RESOLUTION STRUCTURE OF ACIDIC FIBROBLAST GROWTH FACTOR. MUTANT FGF-4-ALA-(24-154), 24 NMR STRUCTURES
Descriptor:FIBROBLAST GROWTH FACTOR 1
Authors:Lozano, R.M., Pineda-Lucena, A., Gonzalez, C., Jimenez, M.A., Cuevas, P., Redondo-Horcajo, M., Sanz, J.M., Rico, M., Gimenez-Gallego, G.
Deposit date:2000-02-24
Release date:2000-03-16
Modification date:2013-05-15
Method:SOLUTION NMR
Cite:1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor
Biochemistry, 39, 2000
1DZD
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HIGH RESOLUTION STRUCTURE OF ACIDIC FIBROBLAST GROWTH FACTOR (27-154), 24 NMR STRUCTURES
Descriptor:ACIDIC FIBROBLAST GROWTH FACTOR
Authors:Lozano, R.M., Pineda-Lucena, A., Gonzalez, C., Jimenez, M.A., Cuevas, P., Redondo-Horcajo, M., Sanz, J.M., Rico, M., Gimenez-Gallego, G.
Deposit date:2000-02-24
Release date:2000-03-16
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor
Biochemistry, 39, 2000
1E0O
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CRYSTAL STRUCTURE OF A TERNARY FGF1-FGFR2-HEPARIN COMPLEX
Descriptor:FIBROBLAST GROWTH FACTOR 1, FIBROBLAST GROWTH FACTOR RECEPTOR 2
Authors:Pellegrini, L., Burke, D.F., Von Delft, F., Mulloy, B., Blundell, T.L.
Deposit date:2000-04-03
Release date:2000-10-23
Modification date:2011-04-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Fibroblast Growth Factor Receptor Ectodomain Bound to Ligand and Heparin
Nature, 407, 2000
1EV2
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CRYSTAL STRUCTURE OF FGF2 IN COMPLEX WITH THE EXTRACELLULAR LIGAND BINDING DOMAIN OF FGF RECEPTOR 2 (FGFR2)
Descriptor:CRYSTAL STRUCTURE OF FGF2 IN COMPLEX WITH THE EXTRACELLULAR LIGAND BINDING DOMAIN OF FGF RECEPTOR 2 (FGFR2)
Authors:Plotnikov, A.N., Hubbard, S.R., Schlessinger, J., Mohammadi, M.
Deposit date:2000-04-19
Release date:2000-05-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.
Cell(Cambridge,Mass.), 101, 2000
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