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2BF9
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Anisotropic refinement of avian (turkey) pancreatic polypeptide at 0. 99 Angstroms resolution.
Descriptor: PANCREATIC HORMONE, ZINC ION
Authors:Tickle, I, Glover, I, Pitts, J, Wood, S, Blundell, T.L.
Deposit date:2004-12-06
Release date:2004-12-08
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (0.99 Å)
Cite:Conformational Flexibility in a Small Globular Hormone. X-Ray Analysis of Avian Pancreatic Polypeptide at 0.98 Angstroms Resolution
Biopolymers, 22, 1983
1PPT
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X-RAY ANALYSIS (1.4-ANGSTROMS RESOLUTION) OF AVIAN PANCREATIC POLYPEPTIDE. SMALL GLOBULAR PROTEIN HORMONE
Descriptor: AVIAN PANCREATIC POLYPEPTIDE, ZINC ION
Authors:Blundell, T.L, Pitts, J.E, Tickle, I.J, Wood, S.P.
Deposit date:1981-01-16
Release date:1981-02-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:X-ray analysis (1. 4-A resolution) of avian pancreatic polypeptide: Small globular protein hormone.
Proc.Natl.Acad.Sci.Usa, 78, 1981
7RT9
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Crystal structures of human PYY and NPY
Descriptor: 4A3B2-A Fab heavy chain, 4A3B2-A Fab light chain, GLYCEROL, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2021-08-12
Release date:2022-03-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of human neuropeptide Y (NPY) and peptide YY (PYY).
Neuropeptides, 92, 2022
7RTA
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Crystal structures of human PYY and NPY
Descriptor: 4A3B2-B Fab heavy chain, 4A3B2-B Fab light chain, Neuropeptide Y, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2021-08-12
Release date:2022-03-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of human neuropeptide Y (NPY) and peptide YY (PYY).
Neuropeptides, 92, 2022
7YON
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BU of 7yon by Molmil
Complex structure of Neuropeptide Y Y2 receptor in complex with PYY(3-36) and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Kang, H, Park, C, Kim, J, Choi, H.-J.
Deposit date:2022-08-01
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling.
Structure, 31, 2023
7X9C
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Cryo-EM structure of neuropeptide Y Y4 receptor in complex with PP and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Tang, T, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-03-15
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors.
Sci Adv, 8, 2022
7YOO
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BU of 7yoo by Molmil
Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Kang, H, Park, C, Kim, J, Choi, H.-J.
Deposit date:2022-08-01
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling.
Structure, 31, 2023
7X9A
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Cryo-EM structure of neuropeptide Y Y1 receptor in complex with NPY and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Tang, T, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-03-15
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors.
Sci Adv, 8, 2022
7VGX
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Neuropeptide Y Y1 Receptor (NPY1R) in Complex with G Protein and its endogeneous Peptide-Agonist Neuropeptide Y (NPY)
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Park, C, Kim, J, Jeong, H, Kang, H, Bang, I, Choi, H.-J.
Deposit date:2021-09-19
Release date:2022-02-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of neuropeptide Y signaling through Y1 receptor
Nat Commun, 13, 2022
7X9B
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Cryo-EM structure of neuropeptide Y Y2 receptor in complex with NPY and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Tang, T, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-03-15
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors.
Sci Adv, 8, 2022
2DEZ
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Structure of human PYY
Descriptor: Peptide YY
Authors:Nygaard, R.
Deposit date:2006-02-20
Release date:2006-07-18
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The PP-Fold Solution Structure of Human Polypeptide YY and Human PYY3-36 As Determined by NMR(,)
Biochemistry, 45, 2006
1RON
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BU of 1ron by Molmil
NMR SOLUTION STRUCTURE OF HUMAN NEUROPEPTIDE Y
Descriptor: NEUROPEPTIDE Y
Authors:Monks, S.A, Karagianis, G, Howlett, G.J, Norton, R.S.
Deposit date:1996-01-11
Release date:1996-08-17
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of human neuropeptide Y.
J.Biomol.NMR, 8, 1996
2DF0
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BU of 2df0 by Molmil
Solution structure of human PYY3-36
Descriptor: Peptide YY
Authors:Nygaard, R.
Deposit date:2006-02-20
Release date:2006-07-18
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The PP-Fold Solution Structure of Human Polypeptide YY and Human PYY3-36 As Determined by NMR(,)
Biochemistry, 45, 2006
1RUU
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BU of 1ruu by Molmil
Solution structure of porcine peptide YY (pPYY) bound to DPC micelles
Descriptor: Peptide YY
Authors:Lerch, M, Mayrhofer, M, Zerbe, O.
Deposit date:2003-12-12
Release date:2004-06-08
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structural similarities of micelle-bound peptide YY (PYY) and neuropeptide Y (NPY) are related to their affinity profiles at the Y receptors.
J.Mol.Biol., 339, 2004
2RLK
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BU of 2rlk by Molmil
Refined solution structure of porcine peptide YY (PYY)
Descriptor: Peptide YY
Authors:Neumoin, A, Mares, J, Lerch-Bader, M, Bader, R, Zerbe, O.
Deposit date:2007-07-21
Release date:2007-08-14
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Probing the formation of stable tertiary structure in a model miniprotein at atomic resolution: determinants of stability of a helical hairpin
J.Am.Chem.Soc., 129, 2007
2L60
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A novel design concept: New Y-receptor agonists with increased membrane recruitment, Y2 affinity and selectivity
Descriptor: Peptide YY
Authors:Pedersen, N.L, Jurt, S, Zerbe, O, Jensen, K.J.
Deposit date:2010-11-11
Release date:2011-10-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A novel design concept: New Y-receptor agonists with increased membrane recruitment, Y2 affinity and selectivity
To be Published
1BBA
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BU of 1bba by Molmil
SEQUENCE-SPECIFIC 1H NMR ASSIGNMENTS AND SOLUTION STRUCTURE OF BOVINE PANCREATIC POLYPEPTIDE
Descriptor: BOVINE PANCREATIC POLYPEPTIDE
Authors:Li, X, Sutcliffe, M.J, Schwartz, T.W, Dobson, C.M.
Deposit date:1992-03-10
Release date:1993-10-31
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Sequence-specific 1H NMR assignments and solution structure of bovine pancreatic polypeptide.
Biochemistry, 31, 1992
1ICY
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BU of 1icy by Molmil
[ALA31,PRO32]-PNPY BOUND TO DPC MICELLES
Descriptor: NEUROPEPTIDE Y
Authors:Bader, R, Rytz, G, Lerch, M, Beck-Sickinger, A.G, Zerbe, O.
Deposit date:2001-04-02
Release date:2002-05-08
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Key motif to gain selectivity at the neuropeptide Y5-receptor: structure and dynamics of micelle-bound [Ala31, Pro32]-NPY.
Biochemistry, 41, 2002
1TZ4
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BU of 1tz4 by Molmil
[hPP19-23]-pNPY bound to DPC Micelles
Descriptor: neuropeptide Y,Pancreatic prohormone,neuropeptide Y
Authors:Lerch, M, Kamimori, H, Folkers, G, Aguilar, M.I, Beck-Sickinger, A.G, Zerbe, O.
Deposit date:2004-07-09
Release date:2005-07-05
Last modified:2020-01-01
Method:SOLUTION NMR
Cite:Strongly Altered Receptor Binding Properties in PP and NPY Chimeras Are Accompanied by Changes in Structure and Membrane Binding
Biochemistry, 44, 2005
1TZ5
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BU of 1tz5 by Molmil
[pNPY19-23]-hPP bound to DPC Micelles
Descriptor: Pancreatic prohormone,neuropeptide Y,Pancreatic prohormone
Authors:Lerch, M, Kamimori, H, Folkers, G, Aguilar, M.I, Beck-Sickinger, A.G, Zerbe, O.
Deposit date:2004-07-09
Release date:2005-07-05
Last modified:2020-01-01
Method:SOLUTION NMR
Cite:Strongly Altered Receptor Binding Properties in PP and NPY Chimeras Are Accompanied by Changes in Structure and Membrane Binding
Biochemistry, 44, 2005
2NA5
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BU of 2na5 by Molmil
NMR solution structure of vitamin B12 conjugates of PYY3-36
Descriptor: CYANOCOBALAMIN, Peptide YY
Authors:Doyle, R.P, Henry, K.E, Roth, C.L, Kerwood, D.J, Allis, D.G, Holz, G.G, Zubieta, J.
Deposit date:2015-12-21
Release date:2016-09-21
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Solution Structure and Constrained Molecular Dynamics Study of Vitamin B12 Conjugates of the Anorectic Peptide PYY(3-36).
Chemmedchem, 11, 2016
2H3T
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trans-(4-aminomethyl)phenylazobenzoic acid-aPP bound to DPC micelles
Descriptor: (3-{(E)-[3-(AMINOMETHYL)PHENYL]DIAZENYL}PHENYL)ACETIC ACID, Pancreatic hormone
Authors:Jurt, S, Aemissegger, A, Guentert, P, Zerbe, O, Hilvert, D.
Deposit date:2006-05-23
Release date:2006-09-12
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:A Photoswitchable Miniprotein Based on the Sequence of Avian Pancreatic Polypeptide
Angew.Chem.Int.Ed.Engl., 45, 2006
2H4B
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cis-4-aminomethylphenylazobenzoic acid-avian pancreatic polypeptide
Descriptor: (3-{(Z)-[3-(AMINOMETHYL)PHENYL]DIAZENYL}PHENYL)ACETIC ACID, Pancreatic hormone
Authors:Jurt, S, Aemissegger, A, Guentert, P, Zerbe, O, Hilvert, D.
Deposit date:2006-05-24
Release date:2006-09-12
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:A Photoswitchable Miniprotein Based on the Sequence of Avian Pancreatic Polypeptide
Angew.Chem.Int.Ed.Engl., 45, 2006
1V1D
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Nucleophilic and General Acid Catalysis at Physiological pH by a Designed Miniature Esterase
Descriptor: PANCREATIC HORMONE
Authors:Nicoll, A, Allemann, R.K.
Deposit date:2004-04-14
Release date:2005-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Nucleophilic and General Acid Catalysis at Physiological Ph by a Designed Miniature Esterase
Org.Biomol.Chem., 2, 2004
2H3S
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cis-Azobenzene-avian pancreatic polypeptide bound to DPC micelles
Descriptor: (3-{(Z)-[3-(AMINOMETHYL)PHENYL]DIAZENYL}PHENYL)ACETIC ACID, Pancreatic hormone
Authors:Jurt, S, Aemissegger, A, Guentert, P, Zerbe, O, Hilvert, D.
Deposit date:2006-05-23
Release date:2006-09-12
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:A Photoswitchable Miniprotein Based on the Sequence of Avian Pancreatic Polypeptide
Angew.Chem.Int.Ed.Engl., 45, 2006

 

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