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1ASZ
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THE ACTIVE SITE OF YEAST ASPARTYL-TRNA SYNTHETASE: STRUCTURAL AND FUNCTIONAL ASPECTS OF THE AMINOACYLATION REACTION
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ASPARTYL-tRNA SYNTHETASE, T-RNA (75-MER)
Authors:Cavarelli, J, Rees, B, Thierry, J.C, Moras, D.
Deposit date:1995-01-19
Release date:1995-05-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction.
EMBO J., 13, 1994
1ASY
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CLASS II AMINOACYL TRANSFER RNA SYNTHETASES: CRYSTAL STRUCTURE OF YEAST ASPARTYL-TRNA SYNTHETASE COMPLEXED WITH TRNA ASP
Descriptor: ASPARTYL-tRNA SYNTHETASE, T-RNA (75-MER)
Authors:Ruff, M, Cavarelli, J, Rees, B, Krishnaswamy, S, Thierry, J.C, Moras, D.
Deposit date:1995-01-19
Release date:1995-05-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Class II aminoacyl transfer RNA synthetases: crystal structure of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp).
Science, 252, 1991
1LYL
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LYSYL-TRNA SYNTHETASE (LYSU) (E.C.6.1.1.6) COMPLEXED WITH LYSINE
Descriptor: LYSINE, LYSYL-TRNA SYNTHETASE (LYSU)
Authors:Onesti, S, Brick, P.
Deposit date:1995-05-03
Release date:1995-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of the lysyl-tRNA synthetase (LysU) from Escherichia coli
Structure, 3, 1995
1BBU
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LYSYL-TRNA SYNTHETASE (LYSS) COMPLEXED WITH LYSINE
Descriptor: LYSINE, PROTEIN (LYSYL-TRNA SYNTHETASE)
Authors:Onesti, S, Desogus, G, Brevet, A, Chen, J, Plateau, P, Blanquet, S, Brick, P.
Deposit date:1998-04-24
Release date:2000-11-10
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding.
Biochemistry, 39, 2000
1BBW
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LYSYL-TRNA SYNTHETASE (LYSS)
Descriptor: PROTEIN (LYSYL-TRNA SYNTHETASE)
Authors:Onesti, S, Desogus, G, Brevet, A, Chen, J, Plateau, P, Blanquet, S, Brick, P.
Deposit date:1998-04-24
Release date:2000-11-10
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding.
Biochemistry, 39, 2000
1B8A
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ASPARTYL-TRNA SYNTHETASE
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PROTEIN (ASPARTYL-TRNA SYNTHETASE)
Authors:Schmitt, E, Moulinier, L, Thierry, J.-C, Moras, D.
Deposit date:1999-01-27
Release date:1999-02-02
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of aspartyl-tRNA synthetase from Pyrococcus kodakaraensis KOD: archaeon specificity and catalytic mechanism of adenylate formation.
EMBO J., 17, 1998
1C0A
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CRYSTAL STRUCTURE OF THE E. COLI ASPARTYL-TRNA SYNTHETASE : TRNAASP : ASPARTYL-ADENYLATE COMPLEX
Descriptor: ADENOSINE MONOPHOSPHATE, ASPARTYL TRNA, ASPARTYL TRNA SYNTHETASE, ...
Authors:Eiler, S, Dock-Bregeon, A.-C, Moulinier, L, Thierry, J.-C, Moras, D.
Deposit date:1999-07-15
Release date:1999-11-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Synthesis of aspartyl-tRNA(Asp) in Escherichia coli--a snapshot of the second step.
EMBO J., 18, 1999
1EFW
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Crystal structure of aspartyl-tRNA synthetase from Thermus thermophilus complexed to tRNAasp from Escherichia coli
Descriptor: ASPARTYL-TRNA, ASPARTYL-TRNA SYNTHETASE
Authors:Briand, C, Poterszman, A, Eiler, S, Webster, G, Thierry, J.-C, Moras, D.
Deposit date:2000-02-10
Release date:2000-06-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:An intermediate step in the recognition of tRNA(Asp) by aspartyl-tRNA synthetase.
J.Mol.Biol., 299, 2000
1EOV
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FREE ASPARTYL-TRNA SYNTHETASE (ASPRS) (E.C. 6.1.1.12) FROM YEAST
Descriptor: ASPARTYL-TRNA SYNTHETASE
Authors:Sauter, C, Lorber, B, Cavarelli, J, Moras, D, Giege, R.
Deposit date:2000-03-24
Release date:2000-09-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The free yeast aspartyl-tRNA synthetase differs from the tRNA(Asp)-complexed enzyme by structural changes in the catalytic site, hinge region, and anticodon-binding domain.
J.Mol.Biol., 299, 2000
1EQR
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CRYSTAL STRUCTURE OF FREE ASPARTYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI
Descriptor: ASPARTYL-TRNA SYNTHETASE, MAGNESIUM ION
Authors:Rees, B, Webster, G, Delarue, M, Boeglin, M, Moras, D.
Deposit date:2000-04-06
Release date:2000-06-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Aspartyl tRNA-synthetase from Escherichia coli: flexibility and adaptability to the substrates.
J.Mol.Biol., 299, 2000
1E1O
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lysyl-tRNA Synthetase (LYSU) hexagonal form, complexed with lysine
Descriptor: GLYCEROL, LYSINE, LYSYL-TRNA SYNTHETASE, ...
Authors:Desogus, G, Todone, F, Brick, P, Onesti, S.
Deposit date:2000-05-09
Release date:2000-07-28
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000
1E1T
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LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM COMPLEXED WITH THE LYSYL_ADENYLATE INTERMEDIATE
Descriptor: ADENOSINE-5'-[LYSYL-PHOSPHATE], GLYCEROL, LYSYL-TRNA SYNTHETASE, ...
Authors:Desogus, G, Todone, F, Brick, P, Onesti, S.
Deposit date:2000-05-10
Release date:2000-07-28
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000
1E22
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LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM complexed with lysine and the non-hydrolysable atp analogue amp-pcp
Descriptor: GLYCEROL, LYSINE, LYSYL-TRNA SYNTHETASE, ...
Authors:Desogus, G, Todone, F, Brick, P, Onesti, S.
Deposit date:2000-05-15
Release date:2000-07-28
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000
1E24
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LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM complexed with lysine and ATP and MN2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, LYSINE, ...
Authors:Desogus, G, Todone, F, Brick, P, Onesti, S.
Deposit date:2000-05-16
Release date:2000-07-28
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000
1G51
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ASPARTYL TRNA SYNTHETASE FROM THERMUS THERMOPHILUS AT 2.4 A RESOLUTION
Descriptor: ADENOSINE MONOPHOSPHATE, ASPARTYL-ADENOSINE-5'-MONOPHOSPHATE, ASPARTYL-TRNA SYNTHETASE, ...
Authors:Poterzsman, A, Delarue, M, Thierry, J.C, Moras, D.
Deposit date:2000-10-30
Release date:2000-12-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Synthesis and recognition of aspartyl-adenylate by Thermus thermophilus aspartyl-tRNA synthetase.
J.Mol.Biol., 244, 1994
1IL2
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Crystal Structure of the E. coli Aspartyl-tRNA Synthetase:Yeast tRNAasp:aspartyl-Adenylate Complex
Descriptor: ASPARTYL TRANSFER RNA, ASPARTYL-ADENOSINE-5'-MONOPHOSPHATE, ASPARTYL-TRNA SYNTHETASE, ...
Authors:Moulinier, L, Eiler, S, Eriani, G, Gangloff, J, Thierry, J.C, Gabriel, K, McClain, W.H, Moras, D.
Deposit date:2001-05-07
Release date:2001-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure of an AspRS-tRNA(Asp) complex reveals a tRNA-dependent control mechanism.
EMBO J., 20, 2001
1L0W
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Aspartyl-tRNA synthetase-1 from space-grown crystals
Descriptor: Aspartyl-tRNA synthetase
Authors:Ng, J.D, Sauter, C, Lorber, B, Kirkland, N, Arnez, J, Giege, R.
Deposit date:2002-02-14
Release date:2002-03-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Comparative analysis of space-grown and earth-grown crystals of an aminoacyl-tRNA synthetase: space-grown crystals are more useful for structural determination.
Acta Crystallogr.,Sect.D, 58, 2002
1N9W
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Crystal structure of the non-discriminating and archaeal-type aspartyl-tRNA synthetase from Thermus thermophilus
Descriptor: aspartyl-tRNA synthetase 2
Authors:Charron, C, Roy, H, Blaise, M, Giege, R, Kern, D.
Deposit date:2002-11-26
Release date:2003-04-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Non-discriminating and discriminating aspartyl-tRNA synthetases differ in the anticodon-binding domain
EMBO J., 22, 2003
1NNH
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Hypothetical protein from Pyrococcus furiosus Pfu-1801964
Descriptor: SODIUM ION, asparaginyl-tRNA synthetase-related peptide
Authors:Tempel, W, Liu, Z.-J, Schubot, F.D, Shah, A, Arendall III, W.B, Rose, J.P, Richardson, D.C, Richardson, J.S, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-01-13
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Hypothetical protein from Pyrococcus furiosus Pfu-1801964
To be published
1WYD
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Crystal Structure of Aspartyl-tRNA synthetase from Sulfolobus tokodaii
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, SULFATE ION, ...
Authors:Maeda, Y, Hossain, M.T, Ubukata, S, Suzuki, K, Sekiguchi, T, Takenaka, A.
Deposit date:2005-02-12
Release date:2006-07-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the nondiscriminating aspartyl-tRNA synthetase from the crenarchaeon Sulfolobus tokodaii strain 7 reveals the recognition mechanism for two different tRNA anticodons
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
1X56
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Crystal structure of asparaginyl-tRNA synthetase from Pyrococcus horikoshii
Descriptor: Asparaginyl-tRNA synthetase
Authors:Iwasaki, W, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-15
Release date:2006-05-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Basis of the Water-assisted Asparagine Recognition by Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 360, 2006
1X55
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Crystal structure of asparaginyl-tRNA synthetase from Pyrococcus horikoshii complexed with asparaginyl-adenylate analogue
Descriptor: 5'-O-[N-(L-ASPARAGINYL)SULFAMOYL]ADENOSINE, Asparaginyl-tRNA synthetase, MAGNESIUM ION, ...
Authors:Iwasaki, W, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-15
Release date:2006-05-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of the Water-assisted Asparagine Recognition by Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 360, 2006
1X54
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Crystal structure of asparaginyl-tRNA synthetase from Pyrococcus horikoshii complexed with asparaginyl-adenylate
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-AMINO-1,4-DIOXOBUTAN-2-AMINIUM ADENOSINE-5'-MONOPHOSPHATE, Asparaginyl-tRNA synthetase, ...
Authors:Iwasaki, W, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-15
Release date:2006-05-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural Basis of the Water-assisted Asparagine Recognition by Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 360, 2006
3BJU
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Crystal Structure of tetrameric form of human lysyl-tRNA synthetase
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, LYSINE, ...
Authors:Guo, M, Yang, X.L, Schimmel, P.
Deposit date:2007-12-04
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation
Proc.Natl.Acad.Sci.Usa, 105, 2008
3E9I
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Lysyl-tRNA synthetase from Bacillus stearothermophilus complexed with L-Lysine hydroxamate-AMP
Descriptor: 5'-O-{(R)-hydroxy[(L-lysylamino)oxy]phosphoryl}adenosine, Lysyl-tRNA synthetase, MAGNESIUM ION, ...
Authors:Sakurama, H, Takita, T, Mikami, B, Itoh, T, Yasukawa, K, Inouye, K.
Deposit date:2008-08-22
Release date:2009-07-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Two crystal structures of lysyl-tRNA synthetase from Bacillus stearothermophilus in complex with lysyladenylate-like compounds: insights into the irreversible formation of the enzyme-bound adenylate of L-lysine hydroxamate
J.Biochem., 145, 2009

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